|   |
315 | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Q | A | A | V | L | G | A | G | I | M | G | G | G | I | A | Y | Q | S | A | W | K | G | V | P | V | V | M | K | D | I | N | D | K | S | L | T | L | G | M | T | E | A | A | K | L | L | N | K | Q | L | E | R | G | K | I | D | G | L | K | L | A | G | V | I | S | T | I | H | P | T | L | D | Y | A | G | F | D | R | V | D |
Query Conservation |   |
  |
|   |
|
|
|
|
|   |
|
|   |   |
|
|   |   |   |
|   |
|
|   |   |
|   |
|   |
|   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|   |
|
|
|
|
|   |
|
|   |   |
|
|   |   |   |
| . |   |
|   |   |
|   |
|   |
|   |   |   |   |   |
|   |   |   |   |   |   |
|   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|
|
Template Sequence |   |
K | V | F | V | I | G | A | G | L | X | G | R | G | I | A | I | A | I | A | . |
S | K | H | E | V | V | L | Q | D | V | S | E | K | A | L | E | A | A | R | E | Q | I | P | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
E | E | L | L | S | K | I | E | F | T | T | T | L | E | K | V | K | D | C | D |
Template Known Secondary structure |   |
 |  |  |  |  |
|
| S |  |  |  |  |  |  |  |  |  |  |  | . | T | T | S |  |  |  |  |  |
| S |
|  |  |  |  |  |  |  |  |  |  | S |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | G | G | G | G | G | G |  |  |  |  | S | S |
| T | T | G | G | G |
| S |
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  | . |
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
2 | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | |
. | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . |
  |
  |   |
395 | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
I | V | V | E | A | V | V | E | N | P | K | V | K | K | A | V | L | A | E | T | E | Q | K | V | R | Q | D | T | V | L | A | S | N | T | S | T | I | P | I | S | E | L | A | N | A | L | E | R | P | E | N | F | C | G | M | H | F | F | N | P | V | H | R | M | P | L | V | E | I | I | R | G | E | K | S | S | D | E | T | I |
Query Conservation |   |
|
|
|
|
|
|   |
|   |
|   |   |
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |
|
|
|
|
|
|
|
|
|   |
|   |   |
|
|   |   |   |   |   |
|   |
|   |
|
|   |
|
|
|
|
|   |   |   |   |   |
|
|
|
|
|   |   |   |   |
|   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|
|
|
|
|   |
|
|   |   |   |
|   |   |   |   |   |   |
|
|   |   |   | . | . |   |
|
|
|
|
|
|
|
|   |
|   |
|   |   |
|
|   |   |   |   |   |
|   |
|   |   |
|   |
|
|   |   |
|   |   |   |   |   |
|
|
|
|
|   |   |   |   |
|   |   |   |   |   |
Template Sequence |   |
I | V | X | E | A | V | F | E | D | L | N | T | K | V | E | V | L | R | E | V | E | R | L | T | . |
. |
N | A | P | L | C | S | N | T | S | V | I | S | V | D | D | I | A | E | R | L | D | S | P | S | R | F | L | G | V | H | W | X | N | P | P | H | V | X | P | L | V | E | I | V | I | S | R | F | T | D | S | K | T | V |
Template Known Secondary structure |   |
 |  |  |  |
|
|
| S |
|  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| . | . |
| S |
|  |  |  |
|
| S | S | S |
|  |  |  |  |  | T | T | S | S |
| G | G | G |  |  |  |  |  |  |
| S | S | T | T | T |
|
|  |  |  |  |  |  |
| T | T |
|
|  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| . | . |
|
|  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
64 | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | |
|
. | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . |
  |
  |   |
475 | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | |
|
|
. | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
| . | . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | K | V | V | A | W | A | S | K | M | G | K | T | P | I | V | V | N | D | C | P | G | F | F | V | N | R | V | L | F | P | Y | F | A | G | F | S | Q | L | L | R | D | G | A | D | F | R | K | I | D | K | V | M | E | K | Q | F | G | W | . |
. |
. |
P | M | G | P | A | Y | L | L | D | V | V | G | I | D | T | A | H | H |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |
|
|
|   |
|
|   |
|   |
|   |
|
|
|
|   |
|
|
|   |   |   |   |   |   |
|
|   |   |
|   |   |
|
|   |   |   |   |   |
|
|   |
|   |   |   |   |   |
|   | . | . | . |
|   |
|
|
|   |
|   |
|   |   |
|
|
|
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |
|
|   |
|
|   |   |   | . | . |   |
|   |
|   |
|
|
|   |   |
|   |   |   |
|
|   |   |
|
|   |
|
|   |
|   |   |
|
|
|   |
|   |   |   |   |   |
|   |   |   |   |   |   |
|
|
|   |   |   |
|   |   |
|
|
|   |   |   |   |
Template Sequence |   |
A | F | V | E | G | F | L | R | E | L | G | K | E | V | V | V | C | K | . |
. |
G | Q | S | L | V | N | R | F | N | A | A | V | L | S | E | A | S | R | X | I | E | E | G | V | R | A | E | D | V | D | R | V | W | K | H | H | L | G | L | L | Y | T | L | F | G | P | L | G | N | L | D | Y | I | G | L | D | V | A | Y | Y |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |  | . | . | S | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
|  |  |  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |
| . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
142 | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | |
|
160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . |
  |
  |   |
552 | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . | . | . | . | . | 610 | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | Q | A | V | M | A | A | G | F | P | Q | R | M | Q | K | D | Y | R | D | A | I | D | A | L | F | D | A | N | R | F | G | Q | K | N | G | L | G | F | W | R | Y | K | E | D | S | K | G | K | P | K | K | E | E | D | A | A | V | E | D | L |
Query Conservation |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|   |   |
|   |
|
|   |
|
|
|   |
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |
|   |   |   |   |   |
| . |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |
|   |
|
|   |
|   |
|   |
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
Template Sequence |   |
A | S | L | Y | L | Y | K | R | F | G | D | . |
E | K | F | K | P | P | E | W | L | Q | E | K | I | K | K | G | E | V | G | V | K | A | G | K | G | I | Y | E | Y | G | P | K | A | Y | E | E | R | V | E | R | L | K | K | L | L | R | F | L |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|
| . | G | G | G | S |
|
|  |  |  |  |  |  |  |  | T | T |
|
| B | G | G | G | T | B | S | S | S | B |
|
| T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
| . |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
220 | . | . | . | . | . | . | . | . | . | 230 | |
. | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . |
  |