Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	S	L	P	F	L	R	T	L	Q	G	D	R	F	F	Q	L	L	I	L	V	G	I	G	L	S	F	F	V	P	F	A	P	K	S	W	P	A	A	I	D	W	H	T	I	I	T	L	S	G	L	M	L	L	T	K	G	V	E	L
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		S	G	Y	F	D	V	L	G	R	K	M	V	R	R	F	A	T	E	R	R	L	A	M	F	M	V	L	A	A	A	L	L	S	T	F	L	T	N	D	V	A	L	F	I	V	V	P	L	T	I	T	L	K	R	L	C	E	I	P	V
Secondary structure
SS confidence
Disorder																																																									?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		N	R	L	I	I	F	E	A	L	A	V	N	A	G	S	L	L	T	P	I	G	N	P	Q	N	I	L	I	W	G	R	S	G	L	S	F	A	G	F	I	A	Q	M	A	P	L	A	G	A	M	M	L	T	L	L	L	L	C	W	C
Secondary structure
SS confidence
Disorder																				?											?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		C	F	P	G	K	A	M	Q	Y	H	T	G	V	Q	T	P	E	W	K	P	R	L	V	W	S	C	L	G	L	Y	I	V	F	L	T	A	L	E	F	K	Q	E	L	W	G	L	V	I	V	A	A	G	F	A	L	L	A	R	R	V
Secondary structure
SS confidence
Disorder					?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		V	L	S	V	D	W	T	L	L	L	V	F	M	A	M	F	I	D	V	H	L	L	T	Q	L	P	A	L	Q	G	V	L	G	N	V	S	H	L	S	E	P	G	L	W	L	T	A	I	G	L	S	Q	V	I	S	N	V	P	S	T
Secondary structure
SS confidence
Disorder																																									?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		I	L	L	L	N	Y	V	P	P	S	L	L	L	V	W	A	V	N	V	G	G	F	G	L	L	P	G	S	L	A	N	L	I	A	L	R	M	A	N	D	R	R	I	W	W	R	F	H	L	Y	S	I	P	M	L	L	W	A	A	L
Secondary structure
SS confidence
Disorder																																									?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.
Sequence		V	G	Y	V	L	L	V	I	L	P	A	N
Secondary structure
SS confidence
Disorder											?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2bbj chain B Region: 144 - 186 Aligned: 40 Modelled: 43 Confidence: 22.0% Identity: 25% PDB header:metal transport/membrane protein Chain: B: PDB Molecule:divalent cation transport-related protein; PDBTitle: crystal structure of the cora mg2+ transporter Phyre2 PDB 3qnq chain D Region: 120 - 196 Aligned: 77 Modelled: 77 Confidence: 17.4% Identity: 10% PDB header:membrane protein, transport protein Chain: D: PDB Molecule:pts system, cellobiose-specific iic component; PDBTitle: crystal structure of the transporter chbc, the iic component from the2 n,n'-diacetylchitobiose-specific phosphotransferase system Phyre2 PDB 2w8a chain C Region: 80 - 203 Aligned: 116 Modelled: 124 Confidence: 9.2% Identity: 9% PDB header:membrane protein Chain: C: PDB Molecule:glycine betaine transporter betp; PDBTitle: crystal structure of the sodium-coupled glycine betaine2 symporter betp from corynebacterium glutamicum with bound3 substrate Phyre2 1 c2bbjB_ 2 c3qnqD_ 3 c2w8aC_

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c2bbjB_ 22.0 25 PDB header:metal transport/membrane protein Chain: B: PDB Molecule:divalent cation transport-related protein; PDBTitle: crystal structure of the cora mg2+ transporter 2 c3qnqD_ 17.4 10 PDB header:membrane protein, transport protein Chain: D: PDB Molecule:pts system, cellobiose-specific iic component; PDBTitle: crystal structure of the transporter chbc, the iic component from the2 n,n'-diacetylchitobiose-specific phosphotransferase system 3 c2w8aC_ 9.2 9 PDB header:membrane protein Chain: C: PDB Molecule:glycine betaine transporter betp; PDBTitle: crystal structure of the sodium-coupled glycine betaine2 symporter betp from corynebacterium glutamicum with bound3 substrate

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0