|   |
4 | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | |
|
|
|
|
|
. | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | |
|
. | . | . | . | 70 | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |
|
|
| . | . | . | . | . | . |
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
| . | . |
|
|
|  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | I | L | V | L | G | A | S | G | Y | I | G | Q | H | L | V | R | T | L | S | Q | Q | G | H | Q | I | L | A | A | A | R | H | V | D | R | L | A | K | L | Q | . |
. |
. |
. |
. |
. |
L | A | N | V | S | C | H | K | V | D | L | S | W | P | D | N | L | P | A | L | L | Q | . |
. |
D | I | D | T | V | Y | F | L | V | H |
Query Conservation |   |
  |
|
|
|
|
|
|
|
|   |
|
|   |   |
|
|   |   |
|
|   |   |
|   |   |
|   |
|
|   |
|   |   |   |   |   |   |   |   |   | . | . | . | . | . | . |   |   |   |
|
|   |
|   |   |
|
|   |
|   |   |   |
|   |   |
|
|   | . | . |
|
|
|   |
|
|   |
|
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|
|
|
|
|
|
|
|
|
|
|   |   |
|
|   |   |
|
|   |   |
|   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|
|   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
Template Sequence |   |
K | L | L | I | T | G | G | C | G | F | L | G | S | N | L | A | S | F | A | L | S | Q | G | I | D | L | I | V | F | D | N | L | S | R | K | G | A | T | D | N | L | H | W | L | S | S | L | G | N | F | E | F | V | H | G | D | I | R | N | K | N | D | V | T | R | L | I | T | K | Y | M | P | D | S | C | F | H | L | A | G |
Template Known Secondary structure |   |
 |  |  |  |  | T | T | T | S |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |  |
|
|
| S | T | T |  |  |  |  |  |  |  |  |  | T | T |
|
|
|  |  |  |  |
|
| T | T |
|  |  |  |  |  |  |  |  |  |  |  |
|
| S |  |  |  |  |
|
|
|
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
3 | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . |
  |
  |   |
76 | . | . | . | 80 | |
|
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . |
Predicted Secondary structure |   |
|
|
|
|  | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
Query SS confidence |   |
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
Query Sequence |   |
S | M | G | E | G | . |
. |
. |
. |
. |
. |
. |
G | D | F | I | A | Q | E | R | Q | V | A | L | N | V | R | D | A | L | R | E | V | P | V | K | Q | L | I | F | L | S | S | L | Q | A | P | P | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
H | E | Q |
Query Conservation |   |
  |   |   |   |   | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |
|
|   |   |   |   |
|   |
|   |
|   |   |
|
|   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |
Alig confidence |   |
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
Q | V | A | M | T | T | S | I | D | N | P | C | M | D | F | E | I | N | V | G | G | T | L | N | L | L | E | A | V | R | Q | Y | N | S | N | C | N | I | I | Y | S | S | T | N | K | V | Y | G | D | L | E | Q | Y | K | Y | N | E | T | E | T | R | Y | T | C | V | D | K | P | N | G | Y | D | E | S | T | Q | L | D | F | H |
Template Known Secondary structure |   |
|
|
|  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| T | T |
|  |  |  |  |  |  |  | G | G | G | G | T | T |
| T | T | S |
|  |  |  |
| S | S |
|  |  |  | T | T |
| T | T |
| B |
| T | T | S |
|
|
|
|
|
Template Predicted Secondary structure |   |
 |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
83 | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . |
  |
  |   |
120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | |
|
|
|
. | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . |  |  |  |
|
|
|  |  |  |  |  |
|
|  |  |  |
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
S | D | H | L | R | A | R | Q | A | T | A | D | I | L | . |
. |
. |
. |
R | E | A | N | V | P | V | T | E | L | R | A | G | I | I | V | G | A | G | S | A | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
A | F | E | V | M | R | D | M | V | Y | N | L | P | V | L | T | P | P | R | W | V | R | S | R | T | T | P | I | A | L |
Query Conservation |   |
|   |
|   |   |
|
|   |   |   |
|   |   |
| . | . | . | . |   |   |   |
|
|   |   |
|
|
|
|   |   |   |
|   |
|   |   |   |   | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
Template Sequence |   |
S | P | Y | G | C | S | K | G | A | A | D | Q | Y | M | L | D | Y | A | R | I | F | G | L | N | T | V | V | F | R | H | S | S | M | Y | G | G | R | Q | F | A | T | Y | D | Q | G | W | V | G | W | F | C | Q | K | A | V | E | I | K | N | G | I | N | K | P | F | T | I | S | G | N | G | K | Q | V | R | D | V | L | H | A |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|  |  |
| T | T |
|
|
| B | T | T | B |
|  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
|
|  |  |  |  | S | S | S |
|
|  |  |  |
|  |  |  |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
163 | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . |
  |
  |   |
185 | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | |
|
|
200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |
|
|
| . | . | . |
|
|
|
|  |  |  |
|
|
|
|
|  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | N | L | L | H | Y | L | V | A | L | L | D | H | P | A | . |
. |
. |
S | E | H | R | I | F | E | A | A | G | P | E | V | L | S | Y | Q | Q | Q | F | E | H | F | M | A | V | S | G | K | R | R | W | L | I | P | I | P | L | P | T | R | W | I | S | V | W | F | L | N | V | I | T | S | V | P | P | T | T | A | R | A | L |
Query Conservation |   |
  |
|
|
|   |   |
|   |   |
|
|   |   |
|   | . | . | . |   |   |
|   |   |   |   |
|   |
|
|
|   |
|
|   |   |
|
|   |   |   |   |
|   |   |   |
|   |   |   |   |   |
|   |
|
|   |   |   |   |   |
|
|   |   |   |
|   |   |
|   |   |
|
|   |   |   |
|   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Sequence |   |
E | D | M | I | S | L | Y | F | T | A | L | A | N | V | S | K | I | R | G | N | A | F | N | I | G | G | T | I | V | N | S | L | S | L | L | E | L | F | K | L | L | E | D | Y | C | N | I | D | M | R | F | T | N | L | P | V | R | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  | T |  |  |  |  | T | T |
|  |  |  |  | S | S |
| G | G | G |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
|
|
|  |  |  |  |
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
243 | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |
  |   |
262 | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | |
. | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 |
Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|  |  |
|
|  |  |  |  |  | . |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
I | Q | G | L | K | H | D | L | L | A | D | D | T | A | L | R | A | . |
L | I | P | Q | R | L | I | A | F | D | D | A | V | R | S | T | L | K | E | E | E | K |
Query Conservation |   |
|   |   |
|   |   |   |   |
|   |   |   |   |   |
|   |   | . |
|   |   |   |   |
|   |   |   |   |   |
|
|   |   |
|
|   |   |   |   |   |
Alig confidence |   |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |   |
|
|   |   |
|   |   |   |   |   |
|   |
|   |   |   |   |   |
|   |   |   |
Template Sequence |   |
. |
E | S | D | Q | R | V | F | V | A | D | I | K | K | I | T | N | A | I | D | W | S | P | K | V | S | A | K | D | G | V | Q | K | M | Y | D | W | T | S | S |
Template Known Secondary structure |   |
. | S | S |
|
| S |  |  |
| B |
|
|  |  |  |  |  |  |  |
|
|
|
|
| S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
. |
|
|
|
|
|  |  |  |  |
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . |
  |