|   |
3 | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | |
|
. | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 |
Predicted Secondary structure |   |
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
| . | . |
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Q | R | I | L | V | L | G | A | S | G | Y | I | G | Q | H | L | V | R | T | L | S | Q | Q | G | H | Q | I | L | A | A | A | R | H | V | D | R | L | A | K | L | Q | L | A | N | V | S | C | H | K | V | D | L | S | W | P | D | N | L | P | A | L | L | Q | . |
. |
D | I | D | T | V | Y | F | L | V | H | S | M | G | E | G |
Query Conservation |   |
|   |
|
|
|
|
|
|
|
|   |
|
|   |   |
|
|   |   |
|
|   |   |
|   |   |
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |
|
|   |
|   |   |   |
|   |   |
|
|   | . | . |
|
|
|   |
|
|   |
|
|   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|
|
|
|
|
|
|
|
|   |
|
|   |   |
|
|   |   |
|   |   |   |
|   |   |
|   |   |   |   |
|   | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
M | R | T | L | I | T | G | A | S | G | Q | L | G | I | E | L | S | R | L | L | S | E | R | H | E | V | I | K | V | Y | N | S | S | . |
. |
. |
. |
. |
. |
. |
. |
. |
E | I | Q | G | G | Y | K | L | D | L | T | D | F | P | R | L | E | D | F | I | I | K | K | R | P | D | V | I | I | N | A | A | A | M | T | D | V | D |
Template Known Secondary structure |   |
|
|  |  |  |  | S | T | T | S |  |  |  |  |  |  |  |  |  |  | T | T | T | S |
|  |  |  |  |
| S | S | S | . | . | . | . | . | . | . | . | . |
|
| S | S | B |
|
|
|
| T | T |
|  |  |  |  |  |  |  |  |  |  |  |
|
| S |  |  |  |  |
|
|
|
|
|
|  |  |
Template Predicted Secondary structure |   |
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | |
|
|
|
|
|
|
|
|
. | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . |
  |
  |   |
|
|
|
|
|
|
81 | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
. | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . |
Predicted Secondary structure |   |
. | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
. |
. |
G | D | F | I | A | Q | E | R | Q | V | A | L | N | V | R | D | A | L | R | E | V | P | V | K | Q | L | I | F | L | S | S | L | Q | A | P | P | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
H | E | Q | S | D | H | L | R | A | R | Q | A | T | A | D | I | L | R | E | A | N | V | P | V | T | E | L |
Query Conservation |   |
. | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |
|
|   |   |   |   |
|   |
|   |
|   |   |
|
|   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . |   |   |   |
|   |
|   |   |
|
|   |   |   |
|   |   |
|   |   |   |
|
|   |   |
|
|
|
Alig confidence |   |
. | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   | . | . |   |   |   |   |   |   |   |   |
Template Sequence |   |
K | C | E | I | E | K | E | K | A | Y | K | I | N | A | E | A | V | R | H | I | V | R | A | G | K | V | I | D | S | Y | I | V | H | I | S | T | D | Y | V | F | D | G | E | K | G | N | Y | K | E | E | D | I | P | N | P | I | N | Y | Y | G | L | S | K | L | L | G | E | T | F | A | . |
. |
L | Q | D | D | S | L | I | I |
Template Known Secondary structure |   |
 |  |  |  |
|  |  |  |  |  |  |  |  | T |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |  |  | G | G | G | S |
| S | S | S |
| S | B |
| T | T | S |
|
|
|
| S | S |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . |
|
| T | T |
|  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  | . | . |  |
|
|
|  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
72 | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | |
|
. | . | . | . | . | . | . | . |
  |
  |   |
144 | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . |
Predicted Secondary structure |   |
 |
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|  |  |
|  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | A | G | I | I | V | G | A | G | S | A | A | F | E | V | M | R | D | M | V | Y | N | L | P | V | L | T | P | P | R | W | V | R | S | R | T | T | P | I | A | L | E | N | L | L | H | Y | L | V | A | L | L | D | H | P | A | S | E | H | R | I | F | E | A | A | G | P | E | V | L | S | Y | Q | Q | Q | F | E | H | F | M |
Query Conservation |   |
|   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |
|   |
|
|
|   |   |
|   |   |
|
|   |   |
|   |   |   |
|   |   |   |   |
|   |
|
|
|   |
|
|   |   |
|
|   |   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . |   |   |   |   |   |   |
|   |
|   |
|   |
|   |
|   |   |   |   |   |   |   |   |   | . | . |   |   |   |   |
|   |   |   | . |   |   |   |
|   |   |
|   |   |   |   |
|   |
Template Sequence |   |
R | T | S | G | I | F | R | N | K | G | F | P | I | Y | V | Y | K | T | L | K | E | G | K | T | V | F | A | F | . |
. |
. |
. |
K | G | Y | Y | S | P | I | S | A | R | K | L | A | S | A | I | L | E | L | L | E | L | R | K | . |
. |
T | G | I | I | H | V | A | G | . |
E | R | I | S | R | F | E | L | A | L | K | I | K |
Template Known Secondary structure |   |
 |  |
|
|  |  | S | S | S | S |  |  |  |  |  |  |  |  |  | T | T | T |
|
|  |  |  |  | . | . | . | . | S |
|  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| . | . |
|  |  |  |  |
|
|
| . |
|
|  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |
|
|
|  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
| . | . | . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| . | . |
|
|  |  |  |
|
|
| . |
|
|
|
|  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | |
|
|
|
. | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | |
|
. | . | . | . | . | . | . | . | |
210 | . | . | . | . | . | . | . | . | . | 220 | . | . |
  |
  |   |
224 | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | V | S | G | K | R | R | W | L | I | P | I | P | L | P | T | R | W | I | S | V | W | F | L | N | V | I | T | S | V | P | P | T | T | A | R | A | L | I | Q | G | L | K | H | D | L | L | A | D | D | T | A | L | R | A | L | I | P | Q | R | L | I | A | F | D |
Query Conservation |   |
  |   |   |
|   |   |   |   |   |
|   |
|
|   |   |   |   |   |
|
|   |   |   |
|   |   |
|   |   |
|
|   |   |   |
|   |   |
|
|   |   |
|   |   |   |   |
|   |   |   |   |   |
|   |   |
|   |   |   |   |
|   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |
|   |
|
|   |   |   |   |
|
|   |   |   |   |   |   |   |
Template Sequence |   |
E | K | F | N | L | P | G | E | V | K | E | V | D | E | V | R | G | W | I | A | K | R | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
P | Y | D | S | S | L | D | S | S | R | A | R | K | I | L | S | T | D | F | Y | T | L | D |
Template Known Secondary structure |   |
 |  |  |
|
|
|
|
|  |  |  |  | S | S |
| T | T |
|
| S |
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
| S | B |
|
| B |
|
|  |  |  |  |  |  |
|
| S |
|
| S | S |
|
|
Template Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|  |  |  |  |
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
223 | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . |
  |