|   |
3 | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | |
. | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | |
|
. | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
| . |
|  |  |  |  |  |  |
|
|  |  |  |  |  |
| . | . |
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Q | R | I | L | V | L | G | A | S | G | Y | I | G | Q | H | L | V | R | T | L | S | Q | Q | G | . |
H | Q | I | L | A | A | A | R | H | V | D | R | L | A | K | . |
. |
L | Q | L | A | N | V | S | C | H | K | V | D | L | S | W | P | D | N | L | P | A | L | L | Q | D | I | D | T | V | Y | F | L | V | H | S | M | G | E |
Query Conservation |   |
|   |
|
|
|
|
|
|
|
|   |
|
|   |   |
|
|   |   |
|
|   |   |
| . |   |   |
|   |
|
|   |
|   |   |   |   |   |   |   | . | . |   |   |   |   |   |
|
|   |
|   |   |
|
|   |
|   |   |   |
|   |   |
|
|   |
|
|
|   |
|
|   |
|
|   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |
|
|
|
|
|
|
|
|   |
|
|   |   |
|   |   |   |
|
|   |   |
|   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |
|   |   |   |
|   |   |   |   |   |
Template Sequence |   |
K | L | V | V | V | F | G | G | T | G | A | Q | G | G | S | V | A | R | T | L | L | E | D | G | T | F | K | V | R | V | V | T | R | N | P | R | K | K | A | A | K | E | L | R | L | Q | G | A | E | V | V | Q | G | D | Q | D | D | Q | V | I | M | E | L | A | L | N | G | A | Y | A | T | F | I | V | T | N | Y | W | E | S |
Template Known Secondary structure |   |
|  |  |  |  |  | T | T | T | S |  |  |  |  |  |  |  |  |  |  |  |  |  |
| S | S |  |  |  |  |  |  | S | S | T | T | S |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |
|
| S | S |
|  |  |  |  |  |  |  |  | T | T |
| S |  |  |  |  |  |
|
| S | S | S |
|
Template Predicted Secondary structure |   |
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
5 | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . |
  |
  |   |
80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | |
|
|
|
. | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|  |  |  |
|
|
|
|
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | G | D | F | I | A | Q | E | R | Q | V | A | L | N | V | R | D | A | L | R | E | V | P | V | K | Q | L | I | F | L | S | S | L | Q | A | . |
. |
. |
. |
P | P | H | E | Q | S | D | H | L | R | A | R | Q | A | T | A | D | I | L | R | E | A | N | V | P | V | T | E | L | R | A | G | I | I | V | G | A | G | S | A | A |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |
|
|   |   |   |   |
|   |
|   |
|   |   |
|
|   |   |   | . | . | . | . |   |   |   |   |   |
|   |
|   |   |
|
|   |   |   |
|   |   |
|   |   |   |
|
|   |   |
|
|
|
|   |   |   |
|   |
|   |   |   |   |   |
Alig confidence |   |
. | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
. |
. |
C | S | Q | E | Q | E | V | K | Q | G | K | L | L | A | D | L | A | R | R | L | G | L | H | Y | V | V | Y | S | G | L | E | N | I | K | K | L | T | A | G | R | L | A | A | A | H | F | D | G | K | G | E | V | E | E | Y | F | R | D | I | G | V | P | M | T | S | V | R | L | P | C | Y | F | E | N | L | L | S | H |
Template Known Secondary structure |   |
. | . | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  | T | T |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  | T |
|
|  |  |  |  |  |
|
|  |  | G | G | G | G | T | T | T |
Template Predicted Secondary structure |   |
. | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
85 | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . |
  |
  |   |
156 | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
F | E | V | M | R | D | M | V | Y | N | L | P | V | L | T | P | P | R | W | V | R | S | R | T | T | P | I | A | L | E | N | L | L | H | Y | L | V | A | L | L | D | H | P | A | S | E | H | R | I | F | E | A | A | G | P | E | V | L | S | Y | Q | Q | Q | F | E | H | F | M | A | V | S | G | K | R | R | W | L | I | P | I |
Query Conservation |   |
  |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |
|   |
|
|
|   |   |
|   |   |
|
|   |   |
|   |   |   |
|   |   |   |   |
|   |
|
|
|   |
|
|   |   |
|
|   |   |   |   |
|   |   |   |
|   |   |   |   |   |
|   |
|
Alig confidence |   |
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
Template Sequence |   |
F | . |
. |
. |
. |
. |
. |
. |
. |
L | P | Q | K | A | P | D | G | K | S | Y | L | V | P | M | D | G | M | S | V | S | D | L | G | P | V | V | L | S | L | L | K | M | P | E | K | Y | V | G | Q | N | I | G | L | S | T | C | R | H | T | A | E | E | Y | A | A | L | L | T | K | H | T | R | K | V | V | H | D | A | K | M |
Template Known Secondary structure |   |
T | . | . | . | . | . | . | . | . |
|
| B | T | T | T | T |  |  |
|
|
|
|
|  |  |  |  |
| G | G | G |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  | T | T |
|  |  |  |
|
| S |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  | T | S |
|
|  |  |
|
|
|
Template Predicted Secondary structure |   |
 | . | . | . | . | . | . | . | . |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
163 | |
|
|
|
|
|
|
|
. | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . |
  |
  |   |
236 | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . |
Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
P | L | P | T | R | W | I | S | V | W | F | L | N | V | I | T | S | V | P | P | T | T | A | R | A | L | I | Q | G | L | K | H | D | L | L | A | D | D | T | A | L | R | A | L | I | P | Q | R | L | I | A | F | D | D | A | V | R | S |
Query Conservation |   |
|   |   |   |   |   |
|
|   |   |   |
|   |   |
|   |   |
|
|   |   |   |
|   |   |
|
|   |   |
|   |   |   |   |
|   |   |   |   |   |
|   |   |
|   |   |   |   |
|   |   |   |   |   |
|
|   |   |
Alig confidence |   |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| . |   |   |   |   |   |   |   |
|
|
|
|   |   |
Template Sequence |   |
T | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
P | E | D | Y | E | K | D | L | A | N | M | F | R | F | Y | A | L | R | P | D | R | D | I | E | L | T | L | R | L | . |
N | P | K | A | L | T | L | D | Q | W | L | E | Q |
Template Known Secondary structure |   |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | T | T | T | T | T |
|
|
|  |  |  |  |  |  |  | T | T |
|
|
|
|
|  |  |  |  |  |  |  | . |
| T | T |
|
|
|  |  |  |  |  |  | T |
Template Predicted Secondary structure |   |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  | . |
|
|
|
|
|
|  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
242 | |
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | |
. | . | . | . | . | . | . | . | 280 | . | . | . | . |
  |