|   |
3 | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | |
. | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | |
. | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | |
. | . | . | . | . | . | . | 70 | . | . | . | . | . | . | |
|
|
Predicted Secondary structure |   |
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
| . |
|  |  |  |  |  |  |
|
|  |  |  |  |  |
|
|
|
| . |
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  | . |  |  |
|
|
|
|  |  |  |  |  |
|
|
| . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
Query Sequence |   |
Q | R | I | L | V | L | G | A | S | G | Y | I | G | Q | H | L | V | R | T | L | S | Q | Q | G | . |
H | Q | I | L | A | A | A | R | H | V | D | R | L | A | K | L | Q | L | . |
A | N | V | S | C | H | K | V | D | L | S | W | P | D | N | L | P | A | . |
L | L | Q | D | I | D | T | V | Y | F | L | V | H | S | . |
. |
. |
Query Conservation |   |
|   |
|
|
|
|
|
|
|
|   |
|
|   |   |
|
|   |   |
|
|   |   |
| . |   |   |
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |   | . |   |   |
|
|   |
|   |   |
|
|   |
|   |   |   |
|   |   | . |
|
|   |
|
|
|   |
|
|   |
|
|   |   | . | . | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
Template Conservation |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |
|
|   |   |
|
|   |   |
|   |
|   |
|   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|
|
|
|   |   |   |   |
Template Sequence |   |
T | R | V | L | I | L | G | V | N | G | F | I | G | N | H | L | T | E | R | L | L | R | E | D | H | Y | E | V | Y | G | L | D | I | G | S | D | A | I | S | R | F | L | N | H | P | H | F | H | F | V | E | G | D | I | S | I | H | S | E | W | I | E | Y | H | V | K | K | C | D | V | V | L | P | L | V | A | I | A | T | P |
Template Known Secondary structure |   |
 |  |  |  |  |  | T | T | T | S |  |  |  |  |  |  |  |  |  |  |  |  | S | S | S |  |  |  |  |  |  |  | S |
|
| T | T | T | G | G | G | T | T |
| T | T |  |  |  |  |  |
|
| T | T | T |
|  |  |  |  |  |  |  |  |  |  |
| S |  |  |  |  |
|
|
|
|
|
| T |
Template Predicted Secondary structure |   |
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
316 | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . |
  |
  |   |
|
|
|
77 | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . |
Predicted Secondary structure |   |
. | . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
M | G | E | G | G | D | F | I | A | Q | E | R | Q | V | A | L | N | V | R | D | A | L | R | E | V | P | V | K | Q | L | I | F | L | S | S | L | Q | A | P | P | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
H | E | Q | S | D | H | L | R | A | R | Q | A | T | A | D | I | L |
Query Conservation |   |
. | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |
|
|   |   |   |   |
|   |
|   |
|   |   |
|
|   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |
|   |
|   |   |
|
|   |   |   |
|   |   |
|
Alig confidence |   |
. | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|   |
|
|
|
|
|
|   |   |   |   | . |   |
|
|
|   |   |
|
|   |   |
|
|
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|   |   |
|
|   |   |
|
|   |   |   |
Template Sequence |   |
I | E | Y | T | R | N | P | L | R | V | F | E | L | D | F | E | E | N | L | R | I | I | R | Y | C | V | K | Y | R | . |
K | R | I | I | F | P | S | T | S | E | V | Y | G | M | C | S | D | K | Y | F | D | E | D | H | S | N | L | I | V | G | P | V | N | K | P | R | W | I | Y | S | V | S | K | Q | L | L | D | R | V | I |
Template Known Secondary structure |   |
 |  |  |  |  | S |  |  |  |  |  |  |  |  | T |  |  |  |  |  |  |  |  |  |  |  |  | T | T | . |
|  |  |  |  |  |
|
| G | G | G | G | B | T |
|
| S | S | S | B |
| T | T | T |
|
|
| B |
|
|
| T | T |
| T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . |
|  |  |  |  |  |
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
396 | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | |
. | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . |
  |
  |   |
|
|
|
|
134 | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
. | . | . | . |  |  |  |
|
|
|  |  |  |  |  |
|
|  |  |  |
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
Query SS confidence |   |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
R | E | A | N | V | P | V | T | E | L | R | A | G | I | I | V | G | A | G | S | A | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
A | F | E | V | M | R | D | M | V | Y | N | L | P | V | L | T | P | P | R | W | V | R | S | R | T | T | P | I | A | L | E | N | L | L | H | Y | L | V | A | L | L | D | H | P |
Query Conservation |   |
. | . | . | . |   |   |   |
|
|   |   |
|
|
|
|   |   |   |
|   |
|   |   |   |   | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |
|   |
|
|
|   |   |
|   |   |
|
|   |   |
|
Alig confidence |   |
. | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |
|
|   |   |   |
|
|
|
|   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |
|   |
|   |
|   |
|   |   |   |
|   |
|
|   |
|   |
|
|
|   |
|
|   |   |
|
|   |   |   |
Template Sequence |   |
W | A | Y | G | E | K | E | G | L | Q | F | T | L | F | R | P | F | N | W | M | G | P | R | L | D | N | L | N | A | A | R | I | G | S | S | R | A | I | T | Q | L | I | L | N | L | V | E | G | S | P | I | K | L | I | D | G | G | K | Q | K | R | C | F | T | D | I | R | D | G | I | E | A | L | Y | R | I | I | E | N | A |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
| S |  |  | S | T | T | S | S |
|  |  |  |  | T | T | T |
| S |
|  |  |  |  |  |  |  |  |  |  |  | T |
|
|  |  |  |  | G | G | G |
|
|  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | G |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
475 | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . |
  |
  |   |
199 | |
|
200 | . | . | . | . | . | . | . | . | . | 210 | . | . | |
. | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . |
Predicted Secondary structure |   |
| . | . |
|
|
|
|  |  |  |
|
|
|
|
|  | . |  |
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |
|
|  |  |
Query SS confidence |   |
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | . |
. |
S | E | H | R | I | F | E | A | A | G | P | E | V | . |
L | S | Y | Q | Q | Q | F | E | H | F | M | A | V | S | G | K | R | R | W | L | I | P | I | P | L | P | T | R | W | I | S | V | W | F | L | N | V | I | T | S | V | P | P | T | T | A | R | A | L | I | Q | G | L | K | H | D | L | L | A | D | D | T | A |
Query Conservation |   |
  | . | . |   |   |
|   |   |   |   |
|   |
|
|
|   | . |
|
|   |   |
|
|   |   |   |   |
|   |   |   |
|   |   |   |   |   |
|   |
|
|   |   |   |   |   |
|
|   |   |   |
|   |   |
|   |   |
|
|   |   |   |
|   |   |
|
|   |   |
|   |   |   |   |
|   |   |   |   |   |
Alig confidence |   |
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |
|   |
|
|
|
|
|
|   |   |   |   |   |
|
|   |
|
|   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . |   |   |   |
|   |
|
|
Template Sequence |   |
G | N | R | C | D | G | E | I | I | N | I | G | N | P | E | N | E | A | S | I | E | E | L | G | E | M | L | L | A | S | F | E | K | H | P | L | R | H | H | F | P | P | F | A | G | F | R | V | V | E | S | S | S | Y | Y | G | K | G | Y | Q | D | V | E | H | . |
. |
. |
. |
. |
. |
. |
. |
. |
R | K | P | S | I | R | N |
Template Known Secondary structure |   |
G | G | T | T | T | T |  |  |  |  |  |
|
| G | G | G |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| T | T | G | G | G | S |
|
|
|
|
|  |  |  |  |
| T |  |  |  |  |
| T | T |
|
|
|
| S |
| . | . | . | . | . | . | . | . | . |
|
| B |
|
|  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
555 | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . | . | . | . | . | 610 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
. | 620 | . | . | . | . | . |
  |
  |   |
276 | . | . | |
. | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  | . |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
Query SS confidence |   |
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | R | A | . |
L | I | P | Q | R | L | I | A | F | D | D | A | V | R | S | T | L | K | E | E | E | K | L | V | N | S | S |
Query Conservation |   |
|   |   | . |
|   |   |   |   |
|   |   |   |   |   |
|
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|   |   |
|
|
|   |
|   |   |
|
|
|
|
|
|   |   |
|
|
|   |
|   |
|   |   |   |   |   |
Template Sequence |   |
A | H | R | C | L | D | W | E | P | K | I | D | M | Q | E | T | I | D | E | T | L | D | F | F | L | R | T | V | D | L | T |
Template Known Secondary structure |   |
 |  |  |  |  |
|
|
|
|
| S |
|  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S |
|
|
|
Template Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
626 | . | . | . | 630 | . | . | . | . | . | . | . | . | . | 640 | . | . | . | . | . | . | . | . | . | 650 | . | . | . | . | . | . |
  |