PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c8ov6C_

Fold library id	PDB Header	Molecule	Title
c8ov6C_	3.77	PDB header: transcription	Chain: C: PDB Molecule: bromodomain-containing protein 4;

Links to external resources
Added to library: Sat May 20 09:25:47 2023

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence T N Q L Q Y L L R V V L K T L W K H Q F A W P F Q Q P V D A V K L N L P D Y Y K I I K T P M D M G T I K K R L E N N Y Y W N A Q E C I Q D F

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T S T T
G G G S S
T
T T
S S
T T
S S T

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence N T M F T N C Y I Y N K P G D D I V L M A E A L E K L F L Q K I N E L P T K V S E Q L K C C S G I L K E M F A K K H A A Y A W P F Y K P V D

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S
T T
T T
T S T T S T T T S G G G S S

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence V E A L G L H D Y C D I I K H P M D M S T I K S K L E A R E Y R D A Q E F G A D V R L M F S N C Y K Y N P P D H E V V A M A R K L Q D V F E

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T T S
S T
S S
T T
S S S
S S S

. . . . . . .

Sequence M R F A K M P

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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Phyre2 is part of Genome3D

	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	T	N	Q	L	Q	Y	L	L	R	V	V	L	K	T	L	W	K	H	Q	F	A	W	P	F	Q	Q	P	V	D	A	V	K	L	N	L	P	D	Y	Y	K	I	I	K	T	P	M	D	M	G	T	I	K	K	R	L	E	N	N	Y	Y	W	N	A	Q	E	C	I	Q	D	F
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)										T								S	T	T		G	G	G	S	S								T		T	T						S	S													T	T			S	S	T
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	N	T	M	F	T	N	C	Y	I	Y	N	K	P	G	D	D	I	V	L	M	A	E	A	L	E	K	L	F	L	Q	K	I	N	E	L	P	T	K	V	S	E	Q	L	K	C	C	S	G	I	L	K	E	M	F	A	K	K	H	A	A	Y	A	W	P	F	Y	K	P	V	D
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)											S		T	T																			T	T																				T	S	T	T	S	T	T	T	S	G	G	G	S	S
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	V	E	A	L	G	L	H	D	Y	C	D	I	I	K	H	P	M	D	M	S	T	I	K	S	K	L	E	A	R	E	Y	R	D	A	Q	E	F	G	A	D	V	R	L	M	F	S	N	C	Y	K	Y	N	P	P	D	H	E	V	V	A	M	A	R	K	L	Q	D	V	F	E
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T	T	T	S			S	T						S	S													T	T			S	S																			S		S	S	S
	.	.	.	.	.	.	.
Sequence	M	R	F	A	K	M	P
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)				T	T