PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c8h8bA_

Fold library id	PDB Header	Molecule	Title
c8h8bA_	3.16	PDB header: toxin	Chain: A: PDB Molecule: putative rhs-family protein;

Links to external resources
Added to library: Sat Jan 21 13:08:20 2023

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence E C H E K A G D P V S L V T G A E I L T L N D V E L P N G F V W S R T Y R S S K A S R N Q G L G Y G W R H A F Q F E L K E V T D E K H N V T

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T S
S T T T
T T T S T T T T
S S S S T T T T
T T S

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence S W E F I S D S A D E I E F E P V E H G S T S Y Q V Y V G A S C H F L N P N I R I V T L S S G D Q Y R F E L V E D I W L L K Q V R N G I F S

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T T
T T
B
T T T
T T
S S S
S S S S
B
S S S

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence T F Q L R Y S R N H R L I E V A H N K R P V L E C Q Y D K Q G R L V E L L N A K T E Q V L T T Y I Y D E Q D D L V G A T N D L G L T E R Y E

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
B
S S S
T T
B
T T S S B
S S S
S
S S S S
T T S

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240 . . . . . . . . . 250 . . . . . . . . . 260 . . . . . . . . . 270 . . . . . . . . . 280

Sequence Y Q D Q H L I A K R V R P T G F T H Y F E W S G E G S S A K C I R N F G D S G I Y D Y R F H Y E G A K S S Y S D S L D N E W T F I H D E Q G

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S S
S S S
S S S G G G
S S
S S
T T S
S S S

. . . . . . . . . 290 . . . . . . . . . 300 . . . . . . . . . 310 . . . . . . . . . 320 . . . . . . . . . 330 . . . . . . . . . 340 . . . . . . . . . 350

Sequence H L L E K S S P T G R T W Q W H Y D H L G R K E K A V F P D N S T T Q Y Q Y N Q Q G Q L I S K L H S S G A Q I Q Y G Y D S L G K L V K T V S

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S S
S S S S
S S S
T T S
T T S
S S

. . . . . . . . . 360 . . . . . . . . . 370 . . . . . . . . . 380 . . . . . . . . . 390 . . . . . . . . . 400 . . . . . . . . . 410 . . . . . . . . . 420

Sequence P D G D L E K A Y Y N S L G Q R V W D I D A L G C V T E Y E Y D K H G Q V V K R E S E D G K K S R W W W D K Q Q R L V A H E V D G T L L R Y

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T S
T T S
S S
B
B
T T S
B S
B
S S S
T T
S S S

. . . . . . . . . 430 . . . . . . . . . 440 . . . . . . . . . 450 . . . . . . . . . 460 . . . . . . . . . 470 . . . . . . . . . 480 . . . . . . . . . 490

Sequence S Y G A T D L V N G I A Y P D G C V A Q I S Y D D Y G R R T S I R Y F N D E D K V G Y S E E Y A Y D E F S R V A Q I Q T P E G V T S Y Q W G

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S S S
T T S
T T S
T T T T B
S S S S
S S

. . . . . . . . . 500 . . . . . . . . . 510 . . . . . . . . . 520 . . . . . . . . . 530 . . . . . . . . . 540 . . . . . . . . . 550 . . . . . . . . . 560

Sequence A L A Q Q E A V I F P D G S H I S Y E Y D Q Q R N L T K L V R S D G L A F E F W Y D S E G L L S G T V G F D G L H S Q F K Y D S M G R I I R

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S S S
T T T
T T S
T T S
T T S S B T T B
T T S

. . . . . . . . . 570 . . . . . . . . . 580 . . . . . . . . . 590 . . . . . . . . . 600 . . . . . . . . . 610 . . . . . . . . . 620 . . . . . . . . . 630

Sequence K D V A D R T V L Y S Y D D A G F L Q H I K A G N G K N I V E N H F N Y T L G G R L T L A S N R H Q T L Q Y Q Y S S F G H L T K R I Q G Q F

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S
S S S S
B S S S
B
B T T B
B
S S
T T T T

. . . . . . . . . 640 . . . . . . . . . 650 . . . . . . . . . 660 . . . . . . . . . 670 . . . . . . . . . 680 . . . . . . . . . 690 . . . . . . . . . 700

Sequence E I G E E F N R V G Q R V S Q T L P D K T S F N F S Y D T N G R L S E I R F S D D S L P K I E F Q Y D V M G R L S V T E T E S F R E S K L Y

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T S
B
T T S
B T T T
S S S S S
T T S
T T

. . . . . . . . . 710 . . . . . . . . . 720 . . . . . . . . . 730 . . . . . . . . . 740 . . . . . . . . . 750 . . . . . . . . . 760 . . . . . . . . . 770

Sequence D G V G R L V E Q Q W S G R E K K Y I Y N A Q N R I S S I L D N T A G A T H Y Q Y D T L G Y V T K V S E A G S T S T F E S D S F G N P A L A

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S S
S S
T T S
T T T
S S S S S S S S
B
T T S
B
S

. . . . . . . . . 780 . . . . . . . . . 790 . . . . . . . . . 800 . . . . . . . . . 810 . . . . . . . . . 820 . . . . . . . . . 830 . . . . . . . . . 840

Sequence D S K V M S D R I E A Y A G V R Y K Y D Q Q G N Q V K R E G D G T V Q K R V F D A L S Q L V E V H G D S S I S H Y E Y D A L G R R T K K I T

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S
S S S S T T
S S
S S
T T S
S S
T T S

. . . . . . . . . 850 . . . . . . . . . 860 . . . . . . . . . 870 . . . . . . . . . 880 . . . . . . . . . 890 . . . . . . . . . 900 . . . . . . . . . 910

Sequence Q N G I T E F L W E G E R L L G E R T A D G F R W Y L Y Q P E T Y I P L A V L E N G S I Y L Y E C D Q V G K P E R L K D S A G N I V W S A S

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S S
T T
S S
T T
S T T
S S
T T S S

. . . . . . . . . 920 . . . . . . . . . 930 . . . . . . . . . 940 . . . . . . . . . 950 . . . . . . . . . 960 . . . . . . . . . 970 . . . . . . . . . 980

Sequence Y D V H G F A S I D V E E V R N P L R F Q G Q Y F D Q E T N L H Y N L A R Y Y D P K L G R F I Q Q D P I S I A G G I N H Y Q Y A V N P I Q W

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T S
S S
B
S T T
T T T T S S S S T T T T S S
T T
S
S S
S
T T T B

. . . . . . . . . 990 . . . . . . . . . 1000 . . . . . . . . . 1010 . . . . . . . . . 1020 . . . . . . .

Sequence I A P T G F L C E E G L K R L Q Q M L A E Y Q A Q S D V P Q E V C D Q I L E A A K E S S V G E

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T S S S
B S S
G G G G T S
S S
T T S

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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Phyre2 is part of Genome3D

	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	E	C	H	E	K	A	G	D	P	V	S	L	V	T	G	A	E	I	L	T	L	N	D	V	E	L	P	N	G	F	V	W	S	R	T	Y	R	S	S	K	A	S	R	N	Q	G	L	G	Y	G	W	R	H	A	F	Q	F	E	L	K	E	V	T	D	E	K	H	N	V	T
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)					T	T	S					S	T	T	T												T	T	T									S	T	T	T	T			S	S	S	S	T	T				T	T										T	T	S
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	S	W	E	F	I	S	D	S	A	D	E	I	E	F	E	P	V	E	H	G	S	T	S	Y	Q	V	Y	V	G	A	S	C	H	F	L	N	P	N	I	R	I	V	T	L	S	S	G	D	Q	Y	R	F	E	L	V	E	D	I	W	L	L	K	Q	V	R	N	G	I	F	S
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)							T	T	T										T	T		B				T	T	T									T	T							S	S	S								S	S	S	S					B				S	S	S
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	T	F	Q	L	R	Y	S	R	N	H	R	L	I	E	V	A	H	N	K	R	P	V	L	E	C	Q	Y	D	K	Q	G	R	L	V	E	L	L	N	A	K	T	E	Q	V	L	T	T	Y	I	Y	D	E	Q	D	D	L	V	G	A	T	N	D	L	G	L	T	E	R	Y	E
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			B					S	S	S								T	T								B		T	T	S	S	B						S	S	S				S							S	S	S	S							T	T	S
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280
Sequence	Y	Q	D	Q	H	L	I	A	K	R	V	R	P	T	G	F	T	H	Y	F	E	W	S	G	E	G	S	S	A	K	C	I	R	N	F	G	D	S	G	I	Y	D	Y	R	F	H	Y	E	G	A	K	S	S	Y	S	D	S	L	D	N	E	W	T	F	I	H	D	E	Q	G
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			S	S	S								S	S	S								S	S	S	G	G	G										S	S										S	S							T	T	S									S	S	S
	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350
Sequence	H	L	L	E	K	S	S	P	T	G	R	T	W	Q	W	H	Y	D	H	L	G	R	K	E	K	A	V	F	P	D	N	S	T	T	Q	Y	Q	Y	N	Q	Q	G	Q	L	I	S	K	L	H	S	S	G	A	Q	I	Q	Y	G	Y	D	S	L	G	K	L	V	K	T	V	S
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)								S	S	S									S	S	S	S							S	S	S									T	T	S								T	T	S									S	S
	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence	P	D	G	D	L	E	K	A	Y	Y	N	S	L	G	Q	R	V	W	D	I	D	A	L	G	C	V	T	E	Y	E	Y	D	K	H	G	Q	V	V	K	R	E	S	E	D	G	K	K	S	R	W	W	W	D	K	Q	Q	R	L	V	A	H	E	V	D	G	T	L	L	R	Y
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T	T	S									T	T	S								S	S					B			B		T	T	S		B	S			B		S	S	S									T	T								S	S	S
	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490
Sequence	S	Y	G	A	T	D	L	V	N	G	I	A	Y	P	D	G	C	V	A	Q	I	S	Y	D	D	Y	G	R	R	T	S	I	R	Y	F	N	D	E	D	K	V	G	Y	S	E	E	Y	A	Y	D	E	F	S	R	V	A	Q	I	Q	T	P	E	G	V	T	S	Y	Q	W	G
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)				S	S	S	S							T	T	S									T	T	S										T	T	T	T	B										S	S	S	S							S	S
	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560
Sequence	A	L	A	Q	Q	E	A	V	I	F	P	D	G	S	H	I	S	Y	E	Y	D	Q	Q	R	N	L	T	K	L	V	R	S	D	G	L	A	F	E	F	W	Y	D	S	E	G	L	L	S	G	T	V	G	F	D	G	L	H	S	Q	F	K	Y	D	S	M	G	R	I	I	R
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	S	S	S								T	T	T									T	T	S								T	T	S									T	T	S	S						B	T	T	B									T	T	S
	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630
Sequence	K	D	V	A	D	R	T	V	L	Y	S	Y	D	D	A	G	F	L	Q	H	I	K	A	G	N	G	K	N	I	V	E	N	H	F	N	Y	T	L	G	G	R	L	T	L	A	S	N	R	H	Q	T	L	Q	Y	Q	Y	S	S	F	G	H	L	T	K	R	I	Q	G	Q	F
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)				S	S									S	S	S	S							B	S	S	S		B								B	T	T	B				B				S	S										T	T								T	T
	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.	.	660	.	.	.	.	.	.	.	.	.	670	.	.	.	.	.	.	.	.	.	680	.	.	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700
Sequence	E	I	G	E	E	F	N	R	V	G	Q	R	V	S	Q	T	L	P	D	K	T	S	F	N	F	S	Y	D	T	N	G	R	L	S	E	I	R	F	S	D	D	S	L	P	K	I	E	F	Q	Y	D	V	M	G	R	L	S	V	T	E	T	E	S	F	R	E	S	K	L	Y
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)								T	T	S					B			T	T	S			B						T	T	T								S	S	S	S	S									T	T	S								T	T
	.	.	.	.	.	.	.	.	.	710	.	.	.	.	.	.	.	.	.	720	.	.	.	.	.	.	.	.	.	730	.	.	.	.	.	.	.	.	.	740	.	.	.	.	.	.	.	.	.	750	.	.	.	.	.	.	.	.	.	760	.	.	.	.	.	.	.	.	.	770
Sequence	D	G	V	G	R	L	V	E	Q	Q	W	S	G	R	E	K	K	Y	I	Y	N	A	Q	N	R	I	S	S	I	L	D	N	T	A	G	A	T	H	Y	Q	Y	D	T	L	G	Y	V	T	K	V	S	E	A	G	S	T	S	T	F	E	S	D	S	F	G	N	P	A	L	A
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)		S	S	S								S	S									T	T	S								T	T	T									S	S	S	S						S	S	S	S						B		T	T	S		B			S
	.	.	.	.	.	.	.	.	.	780	.	.	.	.	.	.	.	.	.	790	.	.	.	.	.	.	.	.	.	800	.	.	.	.	.	.	.	.	.	810	.	.	.	.	.	.	.	.	.	820	.	.	.	.	.	.	.	.	.	830	.	.	.	.	.	.	.	.	.	840
Sequence	D	S	K	V	M	S	D	R	I	E	A	Y	A	G	V	R	Y	K	Y	D	Q	Q	G	N	Q	V	K	R	E	G	D	G	T	V	Q	K	R	V	F	D	A	L	S	Q	L	V	E	V	H	G	D	S	S	I	S	H	Y	E	Y	D	A	L	G	R	R	T	K	K	I	T
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	S				S	S	S	S					T	T							S	S									S	S									T	T	S								S	S									T	T	S
	.	.	.	.	.	.	.	.	.	850	.	.	.	.	.	.	.	.	.	860	.	.	.	.	.	.	.	.	.	870	.	.	.	.	.	.	.	.	.	880	.	.	.	.	.	.	.	.	.	890	.	.	.	.	.	.	.	.	.	900	.	.	.	.	.	.	.	.	.	910
Sequence	Q	N	G	I	T	E	F	L	W	E	G	E	R	L	L	G	E	R	T	A	D	G	F	R	W	Y	L	Y	Q	P	E	T	Y	I	P	L	A	V	L	E	N	G	S	I	Y	L	Y	E	C	D	Q	V	G	K	P	E	R	L	K	D	S	A	G	N	I	V	W	S	A	S
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	S	S									T	T								S	S									T	T						S				T	T									S	S									T	T	S	S
	.	.	.	.	.	.	.	.	.	920	.	.	.	.	.	.	.	.	.	930	.	.	.	.	.	.	.	.	.	940	.	.	.	.	.	.	.	.	.	950	.	.	.	.	.	.	.	.	.	960	.	.	.	.	.	.	.	.	.	970	.	.	.	.	.	.	.	.	.	980
Sequence	Y	D	V	H	G	F	A	S	I	D	V	E	E	V	R	N	P	L	R	F	Q	G	Q	Y	F	D	Q	E	T	N	L	H	Y	N	L	A	R	Y	Y	D	P	K	L	G	R	F	I	Q	Q	D	P	I	S	I	A	G	G	I	N	H	Y	Q	Y	A	V	N	P	I	Q	W
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			T	T	S								S	S				B		S	T	T					T	T	T	T				S	S	S	S				T	T	T	T			S	S			T	T						S		S	S				S		T	T	T	B
	.	.	.	.	.	.	.	.	.	990	.	.	.	.	.	.	.	.	.	1000	.	.	.	.	.	.	.	.	.	1010	.	.	.	.	.	.	.	.	.	1020	.	.	.	.	.	.	.
Sequence	I	A	P	T	G	F	L	C	E	E	G	L	K	R	L	Q	Q	M	L	A	E	Y	Q	A	Q	S	D	V	P	Q	E	V	C	D	Q	I	L	E	A	A	K	E	S	S	V	G	E
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			T	T	S	S	S			B	S	S			G	G	G	G	T	S							S	S														T	T	S