PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c8f4nB_

Fold library id	PDB Header	Molecule	Title
c8f4nB_	2.95	PDB header: membrane protein	Chain: B: PDB Molecule: efflux pump membrane transporter;

Links to external resources
Added to library: Sat Dec 31 11:25:45 2022

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence M A N F F I D R P I F A W V L A I L L C L T G T L A I F S L P V E Q Y P D L A P P N V R V T A N Y P G A S A Q T L E N T V T Q V I E Q N M T

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S
T S
B
S S
S
T T
T T

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence G L D N L M Y M S S Q S S G T G Q A S V T L S F K A G T D P D E A V Q Q V Q N Q L Q S A M R K L P Q A V Q N Q G V T V R K T G D T N I L T I

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T
T T T T S
T T
S

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence A F V S T D G S M D K Q D I A D Y V A S N I Q D P L S R V N G V G D I D A Y G S Q Y S M R I W L D P A K L N S F Q M T A K D V T D A I E S Q

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S S S
S
T T S T T S S
T T

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240 . . . . . . . . . 250 . . . . . . . . . 260 . . . . . . . . . 270 . . . . . . . . . 280

Sequence N A Q I A V G Q L G G T P S V D K Q A L N A T I N A Q S L L Q T P E Q F R D I T L R V N Q D G S E V R L G D V A T V E M G A E K Y D Y L S R

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S
T
S S
S S
S
S T
S
B
T T S
B
T T

. . . . . . . . . 290 . . . . . . . . . 300 . . . . . . . . . 310 . . . . . . . . . 320 . . . . . . . . . 330 . . . . . . . . . 340 . . . . . . . . . 350

Sequence F N G K P A S G L G V K L A S G A N E M A T A E L V L N R L D E L A Q Y F P H G L E Y K V A Y E T T S F V K A S I E D V V K T L L E A I A L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T
S S
T
T T S

. . . . . . . . . 360 . . . . . . . . . 370 . . . . . . . . . 380 . . . . . . . . . 390 . . . . . . . . . 400 . . . . . . . . . 410 . . . . . . . . . 420

Sequence V F L V M Y L F L Q N F R A T L I P T I A V P V V L M G T F S V L Y A F G Y S V N T L T M F A M V L A I G L L V D D A I V V V E N V E R I M

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S T T
B

. . . . . . . . . 430 . . . . . . . . . 440 . . . . . . . . . 450 . . . . . . . . . 460 . . . . . . . . . 470 . . . . . . . . . 480 . . . . . . . . . 490

Sequence S E E G L T P R E A T R K S M G Q I Q G A L V G I A M V L S A V F V P M A F F G G T T G A I Y R Q F S I T I V A A M V L S V L V A M I L T P

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T
T T

. . . . . . . . . 500 . . . . . . . . . 510 . . . . . . . . . 520 . . . . . . . . . 530 . . . . . . . . . 540 . . . . . . . . . 550 . . . . . . . . . 560

Sequence A L C A T L L K P L K K G E H H G Q K G F F A W F N Q M F N R N A E R Y E K G V A K I L H R S L R W I V I Y V L L L G G M V F L F L R L P T

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T S
T
S
S
B

. . . . . . . . . 570 . . . . . . . . . 580 . . . . . . . . . 590 . . . . . . . . . 600 . . . . . . . . . 610 . . . . . . . . . 620 . . . . . . . . . 630

Sequence S F L P L E D R G M F T T S V Q L P S G S T Q Q Q T L K V V E Q I E K Y Y F T H E K D N I M S V F A T V G S G P G G N G Q N V A R M F I R L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S
S
S T T
T T T T T S S
S S
S
S S

. . . . . . . . . 640 . . . . . . . . . 650 . . . . . . . . . 660 . . . . . . . . . 670 . . . . . . . . . 680 . . . . . . . . . 690 . . . . . . . . . 700

Sequence K D W S E R D S K T G T S F A I I E R A T K A F N Q I K E A R V I A S S P P A I S G L G S S A G F D M E L Q D H A G A G H D A L M A A R N Q

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T T S
S S S S S
S S
S S T T T
S S S S S S

. . . . . . . . . 710 . . . . . . . . . 720 . . . . . . . . . 730 . . . . . . . . . 740 . . . . . . . . . 750 . . . . . . . . . 760 . . . . . . . . . 770

Sequence L L A L A A E N P E L T R V R H N G L D D S P Q L Q I D I D Q R K A Q A L G V A I D D I N D T L Q T A W G S S Y V N D F M D R G R V K K V Y

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T S S
T T
S T T

. . . . . . . . . 780 . . . . . . . . . 790 . . . . . . . . . 800 . . . . . . . . . 810 . . . . . . . . . 820 . . . . . . . . . 830 . . . . . . . . . 840

Sequence V Q A A A P Y R M L P D D I N L W Y V R N K D G G M V P F S A F A T S R W E T G S P R L E R Y N G Y S A V E I V G E A A P G V S T G T A M D

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T
S S
T T G G G G
T T
S T T
T T

. . . . . . . . . 850 . . . . . . . . . 860 . . . . . . . . . 870 . . . . . . . . . 880 . . . . . . . . . 890 . . . . . . . . . 900 . . . . . . . . . 910

Sequence I M E S L V K Q L P N G F G L E W T A M S Y Q E R L S G A Q A P A L Y A I S L L V V F L C L A A L Y E S W S V P F S V M L V V P L G V I G A

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S
T T
T T
S T T

. . . . . . . . . 920 . . . . . . . . . 930 . . . . . . . . . 940 . . . . . . . . . 950 . . . . . . . . . 960 . . . . . . . . . 970 . . . . . . . . . 980

Sequence L L A T W M R G L E N D V Y F Q V G L L T V I G L S A K N A I L I V E F A N E M N Q K G H D L F E A T L H A C R Q R L R P I L M T S L A F I

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T
B
T

. . . . . . . . . 990 . . . . . . . . . 1000 . . . . . . . . . 1010 . . . . . . . . . 1020 . . . . . . . . . 1030 . . . .

Sequence F G V L P M A T S T G A G S G G Q H A V G T G V M G G M I S A T I L A I Y F V P L F F V L V R R R F P L K P

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S T
S T T S

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

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Accessibility Statement

Please cite: The Phyre2 web portal for protein modeling, prediction and analysis

Kelley LA et al. Nature Protocols 10, 845-858 (2015) [paper] [Citation link]

© Structural Bioinformatics Group,
Imperial College,
London
Michael Sternberg
Disclaimer

Terms and Conditions

	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	M	A	N	F	F	I	D	R	P	I	F	A	W	V	L	A	I	L	L	C	L	T	G	T	L	A	I	F	S	L	P	V	E	Q	Y	P	D	L	A	P	P	N	V	R	V	T	A	N	Y	P	G	A	S	A	Q	T	L	E	N	T	V	T	Q	V	I	E	Q	N	M	T
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)							S																						T	S		B		S	S				S											T	T										T									T
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	G	L	D	N	L	M	Y	M	S	S	Q	S	S	G	T	G	Q	A	S	V	T	L	S	F	K	A	G	T	D	P	D	E	A	V	Q	Q	V	Q	N	Q	L	Q	S	A	M	R	K	L	P	Q	A	V	Q	N	Q	G	V	T	V	R	K	T	G	D	T	N	I	L	T	I
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T		T	T										T	T	S										T	T																					S
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	A	F	V	S	T	D	G	S	M	D	K	Q	D	I	A	D	Y	V	A	S	N	I	Q	D	P	L	S	R	V	N	G	V	G	D	I	D	A	Y	G	S	Q	Y	S	M	R	I	W	L	D	P	A	K	L	N	S	F	Q	M	T	A	K	D	V	T	D	A	I	E	S	Q
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)					S	S	S		S													T						T	S	T	T							S	S																	T	T
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280
Sequence	N	A	Q	I	A	V	G	Q	L	G	G	T	P	S	V	D	K	Q	A	L	N	A	T	I	N	A	Q	S	L	L	Q	T	P	E	Q	F	R	D	I	T	L	R	V	N	Q	D	G	S	E	V	R	L	G	D	V	A	T	V	E	M	G	A	E	K	Y	D	Y	L	S	R
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	S									T		S	S			S	S									S						S						T			S		B		T	T	S		B															T	T
	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350
Sequence	F	N	G	K	P	A	S	G	L	G	V	K	L	A	S	G	A	N	E	M	A	T	A	E	L	V	L	N	R	L	D	E	L	A	Q	Y	F	P	H	G	L	E	Y	K	V	A	Y	E	T	T	S	F	V	K	A	S	I	E	D	V	V	K	T	L	L	E	A	I	A	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)		T	T												S	S																				T			T	T									S
	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence	V	F	L	V	M	Y	L	F	L	Q	N	F	R	A	T	L	I	P	T	I	A	V	P	V	V	L	M	G	T	F	S	V	L	Y	A	F	G	Y	S	V	N	T	L	T	M	F	A	M	V	L	A	I	G	L	L	V	D	D	A	I	V	V	V	E	N	V	E	R	I	M
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)											S																									T	T			B
	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490
Sequence	S	E	E	G	L	T	P	R	E	A	T	R	K	S	M	G	Q	I	Q	G	A	L	V	G	I	A	M	V	L	S	A	V	F	V	P	M	A	F	F	G	G	T	T	G	A	I	Y	R	Q	F	S	I	T	I	V	A	A	M	V	L	S	V	L	V	A	M	I	L	T	P
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																																T	T																																	T	T
	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560
Sequence	A	L	C	A	T	L	L	K	P	L	K	K	G	E	H	H	G	Q	K	G	F	F	A	W	F	N	Q	M	F	N	R	N	A	E	R	Y	E	K	G	V	A	K	I	L	H	R	S	L	R	W	I	V	I	Y	V	L	L	L	G	G	M	V	F	L	F	L	R	L	P	T
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)						T	S							T						S																																																S		B
	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630
Sequence	S	F	L	P	L	E	D	R	G	M	F	T	T	S	V	Q	L	P	S	G	S	T	Q	Q	Q	T	L	K	V	V	E	Q	I	E	K	Y	Y	F	T	H	E	K	D	N	I	M	S	V	F	A	T	V	G	S	G	P	G	G	N	G	Q	N	V	A	R	M	F	I	R	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)		S							S									S	T	T																				T	T	T	T	T									S	S		S	S		S		S	S
	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.	.	660	.	.	.	.	.	.	.	.	.	670	.	.	.	.	.	.	.	.	.	680	.	.	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700
Sequence	K	D	W	S	E	R	D	S	K	T	G	T	S	F	A	I	I	E	R	A	T	K	A	F	N	Q	I	K	E	A	R	V	I	A	S	S	P	P	A	I	S	G	L	G	S	S	A	G	F	D	M	E	L	Q	D	H	A	G	A	G	H	D	A	L	M	A	A	R	N	Q
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			T	T	T	S		S	S	S	S	S																	S	S									S	S	T	T	T		S	S	S	S								S	S
	.	.	.	.	.	.	.	.	.	710	.	.	.	.	.	.	.	.	.	720	.	.	.	.	.	.	.	.	.	730	.	.	.	.	.	.	.	.	.	740	.	.	.	.	.	.	.	.	.	750	.	.	.	.	.	.	.	.	.	760	.	.	.	.	.	.	.	.	.	770
Sequence	L	L	A	L	A	A	E	N	P	E	L	T	R	V	R	H	N	G	L	D	D	S	P	Q	L	Q	I	D	I	D	Q	R	K	A	Q	A	L	G	V	A	I	D	D	I	N	D	T	L	Q	T	A	W	G	S	S	Y	V	N	D	F	M	D	R	G	R	V	K	K	V	Y
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)									T	T							S	S																			T	T															S										T	T
	.	.	.	.	.	.	.	.	.	780	.	.	.	.	.	.	.	.	.	790	.	.	.	.	.	.	.	.	.	800	.	.	.	.	.	.	.	.	.	810	.	.	.	.	.	.	.	.	.	820	.	.	.	.	.	.	.	.	.	830	.	.	.	.	.	.	.	.	.	840
Sequence	V	Q	A	A	A	P	Y	R	M	L	P	D	D	I	N	L	W	Y	V	R	N	K	D	G	G	M	V	P	F	S	A	F	A	T	S	R	W	E	T	G	S	P	R	L	E	R	Y	N	G	Y	S	A	V	E	I	V	G	E	A	A	P	G	V	S	T	G	T	A	M	D
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)					T	T		S	S		T	T	G	G	G	G						T	T																			S						T	T												T	T
	.	.	.	.	.	.	.	.	.	850	.	.	.	.	.	.	.	.	.	860	.	.	.	.	.	.	.	.	.	870	.	.	.	.	.	.	.	.	.	880	.	.	.	.	.	.	.	.	.	890	.	.	.	.	.	.	.	.	.	900	.	.	.	.	.	.	.	.	.	910
Sequence	I	M	E	S	L	V	K	Q	L	P	N	G	F	G	L	E	W	T	A	M	S	Y	Q	E	R	L	S	G	A	Q	A	P	A	L	Y	A	I	S	L	L	V	V	F	L	C	L	A	A	L	Y	E	S	W	S	V	P	F	S	V	M	L	V	V	P	L	G	V	I	G	A
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)									S		T	T							T																																T		S								T	T
	.	.	.	.	.	.	.	.	.	920	.	.	.	.	.	.	.	.	.	930	.	.	.	.	.	.	.	.	.	940	.	.	.	.	.	.	.	.	.	950	.	.	.	.	.	.	.	.	.	960	.	.	.	.	.	.	.	.	.	970	.	.	.	.	.	.	.	.	.	980
Sequence	L	L	A	T	W	M	R	G	L	E	N	D	V	Y	F	Q	V	G	L	L	T	V	I	G	L	S	A	K	N	A	I	L	I	V	E	F	A	N	E	M	N	Q	K	G	H	D	L	F	E	A	T	L	H	A	C	R	Q	R	L	R	P	I	L	M	T	S	L	A	F	I
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)								T			B																																	T
	.	.	.	.	.	.	.	.	.	990	.	.	.	.	.	.	.	.	.	1000	.	.	.	.	.	.	.	.	.	1010	.	.	.	.	.	.	.	.	.	1020	.	.	.	.	.	.	.	.	.	1030	.	.	.	.
Sequence	F	G	V	L	P	M	A	T	S	T	G	A	G	S	G	G	Q	H	A	V	G	T	G	V	M	G	G	M	I	S	A	T	I	L	A	I	Y	F	V	P	L	F	F	V	L	V	R	R	R	F	P	L	K	P
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			S					T			S	T	T																																					S