PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c7w7rD_

Fold library id	PDB Header	Molecule	Title
c7w7rD_	3.46	PDB header: membrane protein	Chain: D: PDB Molecule: aquaporin 1;

Links to external resources
Added to library: Sat Oct 15 13:05:28 2022

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence M A R E F K S K N F W K A V L A E L V G M T L F I F L S L S A A I G N S T N P D Q E V K V S L A F G L A I A T L A Q S L G H I S G A H L N P

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S S
T

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence A V T L G M L A S C Q I S V L K A V M Y I V A Q M L G S A L A S G I V Y G T R P N G N A N L G L N A L S G V T P S Q G V G I E L L A T F Q L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T S S
S
T T
T T S
S S

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence V L C V I A V T D K R R R D V T G S A P L A I G L S V C L G H L A A I S Y T G C G I N P A R S F G P A L I L N N F E N H W V Y W V G P M C G

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T
T T
S
S
T T T T
T T T T T T T
T T T T

. . . . . . . . . 220 . . . . .

Sequence G V A A A L I Y D F L L A P K

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T T S

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	M	A	R	E	F	K	S	K	N	F	W	K	A	V	L	A	E	L	V	G	M	T	L	F	I	F	L	S	L	S	A	A	I	G	N	S	T	N	P	D	Q	E	V	K	V	S	L	A	F	G	L	A	I	A	T	L	A	Q	S	L	G	H	I	S	G	A	H	L	N	P
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)				S	S	S																											T
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	A	V	T	L	G	M	L	A	S	C	Q	I	S	V	L	K	A	V	M	Y	I	V	A	Q	M	L	G	S	A	L	A	S	G	I	V	Y	G	T	R	P	N	G	N	A	N	L	G	L	N	A	L	S	G	V	T	P	S	Q	G	V	G	I	E	L	L	A	T	F	Q	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)									T	T	S	S																											S				T	T		T	T	S				S	S
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	V	L	C	V	I	A	V	T	D	K	R	R	R	D	V	T	G	S	A	P	L	A	I	G	L	S	V	C	L	G	H	L	A	A	I	S	Y	T	G	C	G	I	N	P	A	R	S	F	G	P	A	L	I	L	N	N	F	E	N	H	W	V	Y	W	V	G	P	M	C	G
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)								T		T	T		S				S																		T	T	T	T						T	T	T	T	T						T	T			T	T	T	T
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.
Sequence	G	V	A	A	A	L	I	Y	D	F	L	L	A	P	K
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)										T	T	T	S