PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c7uftC_

Fold library id	PDB Header	Molecule	Title
c7uftC_	2.90	PDB header: hydrolase	Chain: C: PDB Molecule: alpha-mannosidase;

Links to external resources
Added to library: Sat Nov 19 14:28:51 2022

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence L K V N R E I D R C K R V M R E R V W P H I H Q V L A Q C T V G A V K N P G E P E M P A A F I T R A V S G Q V I F Q P L A V G E P W G T S W

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T S G G G
S
T T
B
T T S
S
T T

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence G T T W I R V E G Q L P E T L P E G R A I E L V F N L G W L E W P V G G H I E A M A Y R A D G T V I K A L H P R N H W M P L V S A D G V K D

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S
T T
S S
S S
T T T S
T T S
S S
S S S
B

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence R V V N P D G S F V V Y V E G A Y N P N V P S F T V T E L G T K P T G K A D E R Y E F S S I D I A A L D Q D M F D Y W A D L D V V T G S L E

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S S
S S S
S S S
S T T S S
S S
S
T T

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240 . . . . . . . . . 250 . . . . . . . . . 260 . . . . . . . . . 270 . . . . . . . . . 280

Sequence N M N D A D P R Y W K L A K A M Q R S I N L W D E K D Y N T L A L A R K A L D K V M H N P A N A S A M T L T A M G H S H I D S A W L W P V R

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T S
T T S T T
T T
T T T T T T
S S
B
S S S S S

. . . . . . . . . 290 . . . . . . . . . 300 . . . . . . . . . 310 . . . . . . . . . 320 . . . . . . . . . 330 . . . . . . . . . 340 . . . . . . . . . 350

Sequence E T E R K V G R T V S N A L A L M D I D P D F T Y V M S A A Q H F A W L E E R H P D L F E R V K A R I A E G R F I P V G G M W V E S D G T M

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T T T T
S S
T S
S
S S
B
S S S

. . . . . . . . . 360 . . . . . . . . . 370 . . . . . . . . . 380 . . . . . . . . . 390 . . . . . . . . . 400 . . . . . . . . . 410 . . . . . . . . . 420

Sequence P C G E S L I R Q I S Y G K R Y F K E K L G V V P N G I W L P D S F G Y T G A W P Q I A K R S G Y S W F L T Q K L C W N D T T R L P H H S F

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S
T T
S
S
B
S
T T
G G G G
S S
S
S

. . . . . . . . . 430 . . . . . . . . . 440 . . . . . . . . . 450 . . . . . . . . . 460 . . . . . . . . . 470 . . . . . . . . . 480 . . . . . . . . . 490

Sequence M W E G V D G S Q I F T H F P P A D K Y D S D M S A N D M A Y V Q S N Y K D K D L S D R G I L L F G Y G D G G G G P I R E M T M R E H R F E

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S S
T T S
S
T T T T T T
S B
B B
B
T T T T S S

. . . . . . . . . 500 . . . . . . . . . 510 . . . . . . . . . 520 . . . . . . . . . 530 . . . . . . . . . 540 . . . . . . . . . 550 . . . . . . . . . 560

Sequence S F E G M P K V E Y G T P D D F F S K A E T E M K A E A G S E M P R W K G E F Y F E L H R K T L T S Q Q E M K R G C R K E E S M L R T V E Y

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S
T T S
T T
S
B
S S
G G G G S S S

. . . . . . . . . 570 . . . . . . . . . 580 . . . . . . . . . 590 . . . . . . . . . 600 . . . . . . . . . 610 . . . . . . . . . 620 . . . . . . . . . 630

Sequence L G V V A S L E S A D Y V Y P T E R I D R I W K T L L L S Q F H D I L P G S A I E W A H R V A R E E Y A R D L K A L S D I A R D A I A A I A

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S S S
T T B T T T T T T
S

. . . . . . . . . 640 . . . . . . . . . 650 . . . . . . . . . 660 . . . . . . . . . 670 . . . . . . . . . 680 . . . . . . . . . 690 . . . . . . . . . 700

Sequence V A N P D V A R I A K A R I S Q F A D V D P W R P A S L V S C G E P V E V N R R E D G S A T L D N G L L C V H V A A D G T V D S M I D L K S

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S T T S
B S S
S S
S S
S S S S
S
T T S
S S
S S S
T T T

. . . . . . . . . 710 . . . . . . . . . 720 . . . . . . . . . 730 . . . . . . . . . 740 . . . . . . . . . 750 . . . . . . . . . 760 . . . . . . . . . 770

Sequence G R E M V A K D H V M G R Y E I L K D E P G V F D A W D V E R D A F L C A T A L A D G H I V S I E T T A D G S A V I V T K N S Y R D D E I S

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T
B
T T
B T
S S
T T T
S T
S S S
T T

. . . . . . . . . 780 . . . . . . . . . 790 . . . . . . . . . 800 . . . . . . . . . 810 . . . . . . . . . 820 . . . . . . . . . 830 . . . . . . . . . 840

Sequence T T I T L R P G K S Q L D F H A D V E W N V P E K L L K V D I P M A L S A S R A Q Y E C Q Y G L I E R P I V K N T E G E E A M F E S C S H R

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T
S S S
S
S S S S S
S T T G G G G S S
S S

. . . . . . . . . 850 . . . . . . . . . 860 . . . . . . . . . 870 . . . . . . . . . 880 . . . . . . . . . 890 . . . . . . . . . 900 . . . . . . . . . 910

Sequence F V R I H D S S Y G I G V A N G S T Y G S D V S S L R D R D D A L A G T M V R M S L V A A P T A P D P R T D I G H H E F D W T V L P C A S V

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S
S S
T T S S
S S
T T
S
S
S S S

. . . . . . . . . 920 . . . . . . . . . 930 . . . . . . . . . 940 . . . . . . . . . 950 . . . . . . . . . 960 . . . . . . . . . 970 . . . . . . . . . 980

Sequence A P L V A A A G E I N A P T I E N M P D I A A P I T L E P I E G T P V I D W I K L A D D G S G D I V A R L Y E A A G A K A K A M L H V G G T

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
B S S B
S S
S S S S
S S S
T T

. . . . . . . . . 990 . . . . . . . . . 1000 . . . . . . . . . 1010 . . . . . . . . . 1020 . . . . . . . . . 1030 . .

Sequence L D G W T V R E T N T L E Q D E S Y P D E P A G L I G G K Q Q A E G A E L A L N P F Q L T T L R L S R A

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S T T
T T S S
T T S
S B S S S S S T T
T T

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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Phyre2 is part of Genome3D

	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	L	K	V	N	R	E	I	D	R	C	K	R	V	M	R	E	R	V	W	P	H	I	H	Q	V	L	A	Q	C	T	V	G	A	V	K	N	P	G	E	P	E	M	P	A	A	F	I	T	R	A	V	S	G	Q	V	I	F	Q	P	L	A	V	G	E	P	W	G	T	S	W
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																		T	S	G	G	G																S														T	T						B			T	T	S			S		T	T
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	G	T	T	W	I	R	V	E	G	Q	L	P	E	T	L	P	E	G	R	A	I	E	L	V	F	N	L	G	W	L	E	W	P	V	G	G	H	I	E	A	M	A	Y	R	A	D	G	T	V	I	K	A	L	H	P	R	N	H	W	M	P	L	V	S	A	D	G	V	K	D
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)													S	S			T	T									S	S			S	S		T	T	T	S								T	T	S								S	S									S	S	S		B
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	R	V	V	N	P	D	G	S	F	V	V	Y	V	E	G	A	Y	N	P	N	V	P	S	F	T	V	T	E	L	G	T	K	P	T	G	K	A	D	E	R	Y	E	F	S	S	I	D	I	A	A	L	D	Q	D	M	F	D	Y	W	A	D	L	D	V	V	T	G	S	L	E
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	S	S			S	S	S																S	S	S			S	T	T	S	S			S	S			S																														T	T
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280
Sequence	N	M	N	D	A	D	P	R	Y	W	K	L	A	K	A	M	Q	R	S	I	N	L	W	D	E	K	D	Y	N	T	L	A	L	A	R	K	A	L	D	K	V	M	H	N	P	A	N	A	S	A	M	T	L	T	A	M	G	H	S	H	I	D	S	A	W	L	W	P	V	R
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T	S		T	T	S															T	T			T	T		T										T	T	T	T	T						S	S												B		S	S	S	S	S
	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350
Sequence	E	T	E	R	K	V	G	R	T	V	S	N	A	L	A	L	M	D	I	D	P	D	F	T	Y	V	M	S	A	A	Q	H	F	A	W	L	E	E	R	H	P	D	L	F	E	R	V	K	A	R	I	A	E	G	R	F	I	P	V	G	G	M	W	V	E	S	D	G	T	M
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)															T	T	T	T	T		S	S																																T	S					S			S	S		B		S	S	S
	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence	P	C	G	E	S	L	I	R	Q	I	S	Y	G	K	R	Y	F	K	E	K	L	G	V	V	P	N	G	I	W	L	P	D	S	F	G	Y	T	G	A	W	P	Q	I	A	K	R	S	G	Y	S	W	F	L	T	Q	K	L	C	W	N	D	T	T	R	L	P	H	H	S	F
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	S																			T	T											S		S		B		S									T	T								G	G	G	G		S	S				S		S
	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490
Sequence	M	W	E	G	V	D	G	S	Q	I	F	T	H	F	P	P	A	D	K	Y	D	S	D	M	S	A	N	D	M	A	Y	V	Q	S	N	Y	K	D	K	D	L	S	D	R	G	I	L	L	F	G	Y	G	D	G	G	G	G	P	I	R	E	M	T	M	R	E	H	R	F	E
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)					S	S	S									T	T	S		S																	T	T	T	T	T	T								S	B		B	B			B								T	T	T	T	S	S
	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560
Sequence	S	F	E	G	M	P	K	V	E	Y	G	T	P	D	D	F	F	S	K	A	E	T	E	M	K	A	E	A	G	S	E	M	P	R	W	K	G	E	F	Y	F	E	L	H	R	K	T	L	T	S	Q	Q	E	M	K	R	G	C	R	K	E	E	S	M	L	R	T	V	E	Y
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	S		T	T	S																									T	T						S		B			S	S		G	G	G	G	S	S	S
	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630
Sequence	L	G	V	V	A	S	L	E	S	A	D	Y	V	Y	P	T	E	R	I	D	R	I	W	K	T	L	L	L	S	Q	F	H	D	I	L	P	G	S	A	I	E	W	A	H	R	V	A	R	E	E	Y	A	R	D	L	K	A	L	S	D	I	A	R	D	A	I	A	A	I	A
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)									S	S	S																		T	T	B	T	T	T	T	T	T		S
	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.	.	660	.	.	.	.	.	.	.	.	.	670	.	.	.	.	.	.	.	.	.	680	.	.	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700
Sequence	V	A	N	P	D	V	A	R	I	A	K	A	R	I	S	Q	F	A	D	V	D	P	W	R	P	A	S	L	V	S	C	G	E	P	V	E	V	N	R	R	E	D	G	S	A	T	L	D	N	G	L	L	C	V	H	V	A	A	D	G	T	V	D	S	M	I	D	L	K	S
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			S	T	T	S			B	S	S					S	S		S	S		S	S	S				S				S									T	T	S							S	S							S	S	S								T	T	T
	.	.	.	.	.	.	.	.	.	710	.	.	.	.	.	.	.	.	.	720	.	.	.	.	.	.	.	.	.	730	.	.	.	.	.	.	.	.	.	740	.	.	.	.	.	.	.	.	.	750	.	.	.	.	.	.	.	.	.	760	.	.	.	.	.	.	.	.	.	770
Sequence	G	R	E	M	V	A	K	D	H	V	M	G	R	Y	E	I	L	K	D	E	P	G	V	F	D	A	W	D	V	E	R	D	A	F	L	C	A	T	A	L	A	D	G	H	I	V	S	I	E	T	T	A	D	G	S	A	V	I	V	T	K	N	S	Y	R	D	D	E	I	S
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T				B		T	T			B	T										S	S		T	T	T				S	T																				S	S	S											T	T
	.	.	.	.	.	.	.	.	.	780	.	.	.	.	.	.	.	.	.	790	.	.	.	.	.	.	.	.	.	800	.	.	.	.	.	.	.	.	.	810	.	.	.	.	.	.	.	.	.	820	.	.	.	.	.	.	.	.	.	830	.	.	.	.	.	.	.	.	.	840
Sequence	T	T	I	T	L	R	P	G	K	S	Q	L	D	F	H	A	D	V	E	W	N	V	P	E	K	L	L	K	V	D	I	P	M	A	L	S	A	S	R	A	Q	Y	E	C	Q	Y	G	L	I	E	R	P	I	V	K	N	T	E	G	E	E	A	M	F	E	S	C	S	H	R
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)							T	T															S	S										S				S							S	S	S						S	S			S	T	T	G	G	G	G	S	S				S	S
	.	.	.	.	.	.	.	.	.	850	.	.	.	.	.	.	.	.	.	860	.	.	.	.	.	.	.	.	.	870	.	.	.	.	.	.	.	.	.	880	.	.	.	.	.	.	.	.	.	890	.	.	.	.	.	.	.	.	.	900	.	.	.	.	.	.	.	.	.	910
Sequence	F	V	R	I	H	D	S	S	Y	G	I	G	V	A	N	G	S	T	Y	G	S	D	V	S	S	L	R	D	R	D	D	A	L	A	G	T	M	V	R	M	S	L	V	A	A	P	T	A	P	D	P	R	T	D	I	G	H	H	E	F	D	W	T	V	L	P	C	A	S	V
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)							S	S								S	S												T	T	S	S																S	S		T	T		S		S												S	S	S
	.	.	.	.	.	.	.	.	.	920	.	.	.	.	.	.	.	.	.	930	.	.	.	.	.	.	.	.	.	940	.	.	.	.	.	.	.	.	.	950	.	.	.	.	.	.	.	.	.	960	.	.	.	.	.	.	.	.	.	970	.	.	.	.	.	.	.	.	.	980
Sequence	A	P	L	V	A	A	A	G	E	I	N	A	P	T	I	E	N	M	P	D	I	A	A	P	I	T	L	E	P	I	E	G	T	P	V	I	D	W	I	K	L	A	D	D	G	S	G	D	I	V	A	R	L	Y	E	A	A	G	A	K	A	K	A	M	L	H	V	G	G	T
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)															B	S	S	B						S								S											S	S	S	S											S	S	S										T	T
	.	.	.	.	.	.	.	.	.	990	.	.	.	.	.	.	.	.	.	1000	.	.	.	.	.	.	.	.	.	1010	.	.	.	.	.	.	.	.	.	1020	.	.	.	.	.	.	.	.	.	1030	.	.
Sequence	L	D	G	W	T	V	R	E	T	N	T	L	E	Q	D	E	S	Y	P	D	E	P	A	G	L	I	G	G	K	Q	Q	A	E	G	A	E	L	A	L	N	P	F	Q	L	T	T	L	R	L	S	R	A
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	S	T	T								T	T	S	S					T	T	S			S	B	S	S	S	S			S	T	T							T	T