PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c7mwdA_

Fold library id	PDB Header	Molecule	Title
c7mwdA_	3.70	PDB header: transferase	Chain: A: PDB Molecule: e3 ubiquitin-protein ligase huwe1;

Links to external resources
Added to library: Sat Jul 31 09:00:49 2021

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence A D C R A L I D K L K D E Q L L L E L Q W V D L L D R F D G I L A D A G Q Q L K M L L L A V L N F T A L L I E Y S S I E H L T T L L A S S D

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T
T S
S S

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence M Q V V L A V L N L L Y V F S K R S N Y I T R L G S D K R T P L L T R L Q H L A E S W G G K E N G F G L A E C C R D L H M M K Y P P S A T T

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T T S S
T T T S
B G G G T B
S
G G G T S S
T T T T

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence L H F E F Y I H I E Q L D K I S E S P S E I M E S L T K M Y S I P K D K Q M L L F T H I R L A H G F S N H R K R L Q A V Q A R L H A I S I L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S
S G G G
S
S
T T
T T S

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240 . . . . . . . . . 250 . . . . . . . . . 260 . . . . . . . . . 270 . . . . . . . . . 280

Sequence V Y S S I L Y N G L I E E L V D V L Q I T D K Q L M E I K A A S L R T L T S I V H K L S S I I D C T G T A S Y H G F L P V L V R N C I Q A M

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T
S S T T
T T T S S S S

. . . . . . . . . 290 . . . . . . . . . 300 . . . . . . . . . 310 . . . . . . . . . 320 . . . . . . . . . 330 . . . . . . . . . 340 . . . . . . . . . 350

Sequence I D P S M D P Y P H Q F A T A L F S F L Y H L A S Y D A G G E A L V S C G M M E A L L K V I K F L G D E Q D Q I T F V T R A V R V V D L I T

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S S S S
T S T T
S S

. . . . . . . . . 360 . . . . . . . . . 370 . . . . . . . . . 380 . . . . . . . . . 390 . . . . . . . . . 400 . . . . . . . . . 410 . . . . . . . . . 420

Sequence N L D M A A F Q S H S G L S I F I Y R L E H E V D L C R K E C P F V I K Q C I P Q R A A L L K S M L N F L K K A I Q D P A F S D G I R H V M

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T
T T
T S T T S T T T G G G T T

. . . . . . . . . 430 . . . . . . . . . 440 . . . . . . . . . 450 . . . . . . . . . 460 . . . . . . . . . 470 . . . . . . . . . 480 . . . . . . . . . 490

Sequence D G S L P T S L K H I I S N A E Y Y G P S L F L L A T E V V T V F V F Q E P S L L S S L Q D N G L T D V M L H A L L I K D V P A T R E V L G

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T S S T T T T T S
G G G T T T T S

. . . . . . . . . 500 . . . . . . . . . 510 . . . . . . . . . 520 . . . . . . . . . 530 . . . . . . . . . 540 . . . . . . . . . 550 . . . . . . . . . 560

Sequence S L P N V F S A L C L N A R G L Q S F V Q C Q P F E R L F K V L L S P D Y L P A M R R R R S S D P L G D T A S N L G S A V D E L M R H Q P T

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) G G G S T
G G G G G
G G G S
S T T T S
T T S G G

. . . . . . . . . 570 . . . . . . . . . 580 . . . . . . . . . 590 . . . . . . . . . 600 . . . . . . . . . 610 . . . . . . . . . 620 . . . . . . . . . 630

Sequence L K T D A T T A I I K L L E E I C N L G R D P K Y I C Q K I P I P L M D Y I L N V M K F V E S I L S N N T T D D H C Q E F V N Q K G L L P L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) G S T T
S
S S S T T

. . . . . . . . . 640 . . . . . . . . . 650 . . . . . . . . . 660 . . . . . . . . . 670 . . . . . . . . . 680 . . . . . . . . . 690 . . . . . . . . . 700

Sequence V T I L G L P N L P I D F P T S A A C Q A V A G V C K S I L T L S H E P K V L Q E G L L Q L D S I L S S L E P L H R P I E S P G G S V L L R

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) G G G
T T S
T T S T T S
T T T
G G G T S
S S S

. . . . . . . . . 710 . . . . . . . . . 720 . . . . . . . . . 730 . . . . . . . . . 740 . . . . . . . . . 750 . . . . . . . . . 760 . . . . . . . . . 770

Sequence E L A C A G N V A D A T L S A Q A T P L L H A L T A A H A Y I M M F V H T C R V G Q S E I R S I S V N Q W G S Q L G L S V L S K L S Q L Y C

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T S T T
T T G G G
T T T
S
T S

. . . . . . . . . 780 . . . . . . . . . 790 . . . . . . . . . 800 . . . . . . . . . 810 . . . . . . . . . 820 . . . . . . . . . 830 . . . . . . . . . 840

Sequence S L V W E S T V L L S L C T P N S L P S G C E F G Q A D M Q K L V A M A A R I K Q I K P L L S A S S R L G R A L A E L F G L L V K L C V G P

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S
S S S S
S
S S

. . . . . . . . . 850 . . . . . . . . . 860 . . . . . . . . . 870 . . . . . . . . . 880 . . . . . . . . . 890 . . . . . . . . . 900 . . . . . . . . . 910

Sequence A A R S T A S A L T K L L T K G L S W Q P P P Y T P T P R F R L T F F I C S V G F T S P M L F D E R K Y P Y H L M L Q K F L C S G G H N A L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T
S
T B
T T S
B
S S S

. . . . . . . . . 920 . . . . . . . . . 930 . . . . . . . . . 940 . . . . . . . . . 950 . . . . . . . . . 960 . . . . . . . . . 970 . . . . . . . . . 980

Sequence F E T F N W A L S M G G K V P V S E G L E H S D L P D G T G E F L D A W L M L V E K M V N P T T V L E S P H S L P A K N F P Q F S A L R F L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T T T S
T T
T T
T T
T S
T T

. . . . . . . . . 990 . . . . . . . . . 1000 . . . . . . . . . 1010 . . . . . . . . . 1020 . . . . . . . . . 1030 . . . . . . . . . 1040 . . . . . . . . . 1050

Sequence V V T Q K A A F T C I K N L W N R K P L K V Y G G R M A E S M L A I L C H I L R G E P V I R E R E Q D E L H T F T D T M L P G C F H L L D E

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T S S S
S S S S T T

. . . . . . . . . 1060 . . . . . . . . . 1070 . . . . . . . . . 1080 . . . . . . . . . 1090 . . . . . . . . . 1100 . . . . . . . . . 1110 . . . . . . . . . 1120

Sequence L P D T V Y R V C D L I M T A I K R N G A D Y R D M I L K Q V V N Q V W E A A D V L I K A A L P L T T S D T K T V S E W I S Q M A T L P Q A

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
G G G S
T
S
S S
S S
S S S

. . . . . . . . . 1130 . . . . . . . . . 1140 . . . . . . . . . 1150 . . . . . . . . . 1160 . . . . . . . . . 1170 . . . . . . . . . 1180 . . . . . . . . . 1190

Sequence S N L A T R I L L L T L L F E E L K L P C A W V V E S S G I L N V L I K L L E V V Q P C L Q A A K E Q K E V Q T P K W I T P V L L L I D F Y

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S T
T
T T

. . . . . . . . . 1200 . . . . . . . . . 1210 . . . . . . . . . 1220 . . . . . . . . . 1230 . . . . . . . . . 1240 . . . . . . . . . 1250 . . . . . . . . . 1260

Sequence E K T A I S S K R R A Q M T K Y L Q S N S N N W R W F D D R S G R W C S Y S A S N N S T I D S A W K S G E T S V R F T A G R R R Y T V Q F T

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T S
S S S
T T T T
T T
S T T T T

. . . . . . . . . 1270 . . . . . . . . . 1280 . . . . . . . . . 1290 . . . . . . . . . 1300 . . . . . . . . . 1310 . . . . . . . . . 1320 . . . . . . . . . 1330

Sequence T M V Q V N E E T G N R R P V M L T L L I L I Q G L T E D M V T V L I R A C V S M L G V P V D P D T L H A T L R L C L R L T R D H K Y A M M

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T T T T
T T
T T S

. . . . . . . . . 1340 . . . . . . . . . 1350 . . . . . . . . . 1360 . . . . . . . . . 1370 . . . . . . . . . 1380 . . . . . . . . . 1390 . . . . . . . . . 1400

Sequence F A E L K S T R M I L N L T Q S S G F N G F T P L V T L L L R H I I E D P C T L R H T M E K V V R S A A T S G A G S T T S G V V S G S L G S

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T
B G G G
T T
S
T T
T T
S S G G

. . . . . . . . . 1410 . . . . . . . . . 1420 . . . . . . . . . 1430 . . . . . . . . . 1440 . . . . . . . . . 1450 . . . . . . . . . 1460 . . . . . . . . . 1470

Sequence R E I N Y I L R V L G P A A C R N P D I F T E V A N C C I R I A L P A P R G S G T A S D D E F E N L R I K G P N A V Q L V K T T P L K P S P

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) G B T
S S S
T T T S S S S
B

. . . . . . . . . 1480 . . . . . . . . . 1490 . . . . . . . . . 1500 . . . . . . . . . 1510 . . . . . . . . . 1520 . . . . . . . . . 1530 . . . . . . . . . 1540

Sequence L P V I P D T I K E V I Y D M L N A L A S K P L M P T S T I L R L L A E L V R S Y V G I A T L I A N Y S Y T V G Q S E L I K E D C S V L A F

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
B S S
B
T T S S T T
S
B

. . . . . . . . . 1550 . . . . . . . . . 1560 . . . . . . . . . 1570 . . . . . . . . . 1580 . . . . . . . . . 1590 . . . . . . . . . 1600 . . . . . . . . . 1610

Sequence V L D H L L P H T Q N A E D K D T P A L A R L F L A S L A A A G S G T D A Q V A L V N E V K A A L G R A L A M A E S T E K H A R L Q A V M C

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T S S
S S
S S T T S
T T S
S S

. . . . . . . . . 1620 . . . . . . . . . 1630 . . . . . . . . . 1640 . . . . . . . . . 1650 . . . . . . . . . 1660 . . . . . . . . . 1670 . . . . . . . . . 1680

Sequence I I S T I M E N N I I R L F L K K G L V N D L A R V P H S L D L S S P N M A N T V N A A L K P L E T L S R I V N Q L S S I P T A L T R W T E

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T T G G G G S
T T
T T
T T S

. . . . . . . . . 1690 . . . . . . . . . 1700 . . . . . . . . . 1710 . . . . . . . . . 1720 . . . . . . . . . 1730 . . . . . . . . . 1740 . . . . . . . . . 1750

Sequence E C K V L D A E S M H D C V S V V K V S I V N H L E F L R D E E L E E R R E K R R K Q L L L D H E A L S C L L V L L F V D E P K L N T S R L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T
S
G G G T S
S S S

. . . . . . . . . 1760 . . . . . . . . . 1770 . . . . . . . . . 1780 . . . . . . . . . 1790 . . . . . . . . . 1800 . . . . . . . . . 1810 . . . . . . . . . 1820

Sequence H R V L R N L C Y H A Q T R H W V I R S L L S I L Q R S S S W L S V S M D A A L G C R T N I F Q I Q T V H I H P Q A A P V V C R H V L D T L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T S
T T S
T T T

. . . . . . . . . 1830 . . . . . . . . . 1840 . . . . . . . . . 1850 . . . . . . . . . 1860 . . . . . . . . . 1870 . . . . . . . . . 1880 . . . . . . . . . 1890

Sequence I Q L A K V D F W D L L V K L D N M E A S P L G Q L M N M L S H P V I R R S S L L T E K L L R L L S L I S I G L T E N Q L Q L S V E V L T S

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S T G G G S
T

. . . . . . . . . 1900 . . . . . . . . . 1910 . . . . . . . . . 1920 . . . . . . . . . 1930 . . . . . . . . . 1940 . . . . . . . . . 1950 . . . . . . . . . 1960

Sequence E E G L E D A A N V L L Q L S R G D S G T R D T V L K L L L N G A R H L G Y T L C K Q I G T L L A E L R E Y N L E E L Q L P S M S M L T S K

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T
G G G S T

. . . . . . . . . 1970 . . . . . . . . . 1980 . . . . . . . . . 1990 . . . . . . . . . 2000 . . . . . . . . . 2010 . . . . . . . . . 2020 . . . . . . . . . 2030

Sequence T S T Q K F F L R V L Q V I I Q L R D L S L D E L W D M L G E C L K E L E E S H D Q H A V L V L Q P A V E A F F L V H A T E Q K F L R F A E

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T
T T T
S G G G G G G S S

. . . . . . . . . 2040 . . . . . . . . . 2050 . . . . . . . . . 2060 . . . . . . . . . 2070 . . . . . . . . . 2080 . . . . . . . . . 2090 . . . . . . . . . 2100

Sequence T H R T V L N Q I L R Q S T T H L A D G P F A V L V D Y I R V L D F D V K R K Y F R Q E L E R L D E G L R K E D M A V H V R R D H V F E D S

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T
S
T T T S G G G G G G S
G G G S
T T T S
T T T

. . . . . . . . . 2110 . . . . . . . . . 2120 . . . . . . . . . 2130 . . . . . . . . . 2140 . . . . . . . . . 2150 . . . . . . . . . 2160 . . . . . . . . . 2170

Sequence Y R E L H R K S P E E M K N R L Y I V F E G E E G Q D A G G L L R E W Y M I I S R E M F N P M Y A L F R T S P G D R V T Y T I N P S S H C N

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T S
T S T T
T T
T T T T
T T T S S S B
T T G G G S

. . . . . . . . . 2180 . . . . . . . . . 2190 . . . . . . . . . 2200 . . . . . . . . . 2210 . . . . . . . . . 2220 . . . . . . . . . 2230 . . . . . . . . . 2240

Sequence P N H L S Y F K F V G R I V A K A V Y D N R L L E C Y F T R S F Y K H I L G K S V R Y T D M E S E D Y H F Y Q G L V Y L L E N D V S T L G Y

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T T
B
T
G G G
T T S
G G G T S S

. . . . . . . . . 2250 . . . . . . . . . 2260 . . . . . . . . . 2270 . . . . . . . . . 2280 . . . . . . . . . 2290 . . . . . . . . . 2300 . . . . . . . . . 2310

Sequence D L T F S T E V Q E F G V C E V R D L K V T E E N K K E Y V H L V C Q M R M T G A I R K Q L A A F L E G F Y E I I P K R L I S I F T E Q E L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S T T
T T T G G G S
T T S

. . . . . . . . . 2320 . . . . . . . . . 2330 . . . . . . . . . 2340 . . . . . . . . . 2350 . . . . . . . . . 2360 . . . . . . . . . 2370 . . . . . . . . . 2380

Sequence E L L I S G L P T I D I D D L K S N T E Y H K Y Q S N S I Q I Q W F W R A L R S F D Q A D R A K F L Q F V T G T S K V P L Q G F A A L E G M

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T
T S S S
T T
S
S
T T
G G G
T

. . . . . . . . . 2390 . . . . . . . . . 2400 . . . . . . . . . 2410 . . . . . . . . . 2420 . . . . . . .

Sequence N G I Q K F Q I H R D D R S T D R L P S A H T C F N Q L D L P A Y E S F E K L R H M L L L A I

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T
S
T T S
T T T T
S

Download: PDB structure FASTA sequence
Hidden Markov model

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Accessibility Statement

Please cite: The Phyre2 web portal for protein modeling, prediction and analysis

Kelley LA et al. Nature Protocols 10, 845-858 (2015) [paper] [Citation link]

© Structural Bioinformatics Group,
Imperial College,
London
Michael Sternberg
Disclaimer

Terms and Conditions

	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	A	D	C	R	A	L	I	D	K	L	K	D	E	Q	L	L	L	E	L	Q	W	V	D	L	L	D	R	F	D	G	I	L	A	D	A	G	Q	Q	L	K	M	L	L	L	A	V	L	N	F	T	A	L	L	I	E	Y	S	S	I	E	H	L	T	T	L	L	A	S	S	D
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																																																						T	T											T	S		S	S
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	M	Q	V	V	L	A	V	L	N	L	L	Y	V	F	S	K	R	S	N	Y	I	T	R	L	G	S	D	K	R	T	P	L	L	T	R	L	Q	H	L	A	E	S	W	G	G	K	E	N	G	F	G	L	A	E	C	C	R	D	L	H	M	M	K	Y	P	P	S	A	T	T
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																				T	T	T	S	S		T	T	T													S				B	G	G	G	T	B							S		G	G	G	T	S	S		T	T	T	T
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	L	H	F	E	F	Y	I	H	I	E	Q	L	D	K	I	S	E	S	P	S	E	I	M	E	S	L	T	K	M	Y	S	I	P	K	D	K	Q	M	L	L	F	T	H	I	R	L	A	H	G	F	S	N	H	R	K	R	L	Q	A	V	Q	A	R	L	H	A	I	S	I	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)										S		S	G	G	G		S													S				T	T															T	T	S
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280
Sequence	V	Y	S	S	I	L	Y	N	G	L	I	E	E	L	V	D	V	L	Q	I	T	D	K	Q	L	M	E	I	K	A	A	S	L	R	T	L	T	S	I	V	H	K	L	S	S	I	I	D	C	T	G	T	A	S	Y	H	G	F	L	P	V	L	V	R	N	C	I	Q	A	M
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)								T	T													S	S	T	T																										T	T	T	S	S	S	S
	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350
Sequence	I	D	P	S	M	D	P	Y	P	H	Q	F	A	T	A	L	F	S	F	L	Y	H	L	A	S	Y	D	A	G	G	E	A	L	V	S	C	G	M	M	E	A	L	L	K	V	I	K	F	L	G	D	E	Q	D	Q	I	T	F	V	T	R	A	V	R	V	V	D	L	I	T
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)		S	S	S	S																				T	S										T	T														S	S
	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence	N	L	D	M	A	A	F	Q	S	H	S	G	L	S	I	F	I	Y	R	L	E	H	E	V	D	L	C	R	K	E	C	P	F	V	I	K	Q	C	I	P	Q	R	A	A	L	L	K	S	M	L	N	F	L	K	K	A	I	Q	D	P	A	F	S	D	G	I	R	H	V	M
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T	T								T	T																																															T	S	T	T	S	T	T	T	G	G	G	T	T
	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490
Sequence	D	G	S	L	P	T	S	L	K	H	I	I	S	N	A	E	Y	Y	G	P	S	L	F	L	L	A	T	E	V	V	T	V	F	V	F	Q	E	P	S	L	L	S	S	L	Q	D	N	G	L	T	D	V	M	L	H	A	L	L	I	K	D	V	P	A	T	R	E	V	L	G
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T	S	S										T	T	T	T	T	S																				G	G	G							T	T										T	T	S
	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560
Sequence	S	L	P	N	V	F	S	A	L	C	L	N	A	R	G	L	Q	S	F	V	Q	C	Q	P	F	E	R	L	F	K	V	L	L	S	P	D	Y	L	P	A	M	R	R	R	R	S	S	D	P	L	G	D	T	A	S	N	L	G	S	A	V	D	E	L	M	R	H	Q	P	T
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)										G	G	G	S									T							G	G	G	G	G		G	G	G					S		S	T	T	T	S		T	T																	S	G	G
	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630
Sequence	L	K	T	D	A	T	T	A	I	I	K	L	L	E	E	I	C	N	L	G	R	D	P	K	Y	I	C	Q	K	I	P	I	P	L	M	D	Y	I	L	N	V	M	K	F	V	E	S	I	L	S	N	N	T	T	D	D	H	C	Q	E	F	V	N	Q	K	G	L	L	P	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	G																					S	T	T																												S		S	S	S								T	T
	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.	.	660	.	.	.	.	.	.	.	.	.	670	.	.	.	.	.	.	.	.	.	680	.	.	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700
Sequence	V	T	I	L	G	L	P	N	L	P	I	D	F	P	T	S	A	A	C	Q	A	V	A	G	V	C	K	S	I	L	T	L	S	H	E	P	K	V	L	Q	E	G	L	L	Q	L	D	S	I	L	S	S	L	E	P	L	H	R	P	I	E	S	P	G	G	S	V	L	L	R
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			G	G	G		T	T	S		T	T	S	T	T	S																				T															T	T		G	G	G	T	S			S	S	S
	.	.	.	.	.	.	.	.	.	710	.	.	.	.	.	.	.	.	.	720	.	.	.	.	.	.	.	.	.	730	.	.	.	.	.	.	.	.	.	740	.	.	.	.	.	.	.	.	.	750	.	.	.	.	.	.	.	.	.	760	.	.	.	.	.	.	.	.	.	770
Sequence	E	L	A	C	A	G	N	V	A	D	A	T	L	S	A	Q	A	T	P	L	L	H	A	L	T	A	A	H	A	Y	I	M	M	F	V	H	T	C	R	V	G	Q	S	E	I	R	S	I	S	V	N	Q	W	G	S	Q	L	G	L	S	V	L	S	K	L	S	Q	L	Y	C
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)				T	S	T	T		T	T	G	G	G		T	T	T																						S															T	S
	.	.	.	.	.	.	.	.	.	780	.	.	.	.	.	.	.	.	.	790	.	.	.	.	.	.	.	.	.	800	.	.	.	.	.	.	.	.	.	810	.	.	.	.	.	.	.	.	.	820	.	.	.	.	.	.	.	.	.	830	.	.	.	.	.	.	.	.	.	840
Sequence	S	L	V	W	E	S	T	V	L	L	S	L	C	T	P	N	S	L	P	S	G	C	E	F	G	Q	A	D	M	Q	K	L	V	A	M	A	A	R	I	K	Q	I	K	P	L	L	S	A	S	S	R	L	G	R	A	L	A	E	L	F	G	L	L	V	K	L	C	V	G	P
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)														S		S	S	S	S		S			S	S
	.	.	.	.	.	.	.	.	.	850	.	.	.	.	.	.	.	.	.	860	.	.	.	.	.	.	.	.	.	870	.	.	.	.	.	.	.	.	.	880	.	.	.	.	.	.	.	.	.	890	.	.	.	.	.	.	.	.	.	900	.	.	.	.	.	.	.	.	.	910
Sequence	A	A	R	S	T	A	S	A	L	T	K	L	L	T	K	G	L	S	W	Q	P	P	P	Y	T	P	T	P	R	F	R	L	T	F	F	I	C	S	V	G	F	T	S	P	M	L	F	D	E	R	K	Y	P	Y	H	L	M	L	Q	K	F	L	C	S	G	G	H	N	A	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																							T	T		S		T																			B		T	T	S		B											S	S	S
	.	.	.	.	.	.	.	.	.	920	.	.	.	.	.	.	.	.	.	930	.	.	.	.	.	.	.	.	.	940	.	.	.	.	.	.	.	.	.	950	.	.	.	.	.	.	.	.	.	960	.	.	.	.	.	.	.	.	.	970	.	.	.	.	.	.	.	.	.	980
Sequence	F	E	T	F	N	W	A	L	S	M	G	G	K	V	P	V	S	E	G	L	E	H	S	D	L	P	D	G	T	G	E	F	L	D	A	W	L	M	L	V	E	K	M	V	N	P	T	T	V	L	E	S	P	H	S	L	P	A	K	N	F	P	Q	F	S	A	L	R	F	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)										T	T	T	T	S						T	T		T	T			T	T																						T	S		T	T
	.	.	.	.	.	.	.	.	.	990	.	.	.	.	.	.	.	.	.	1000	.	.	.	.	.	.	.	.	.	1010	.	.	.	.	.	.	.	.	.	1020	.	.	.	.	.	.	.	.	.	1030	.	.	.	.	.	.	.	.	.	1040	.	.	.	.	.	.	.	.	.	1050
Sequence	V	V	T	Q	K	A	A	F	T	C	I	K	N	L	W	N	R	K	P	L	K	V	Y	G	G	R	M	A	E	S	M	L	A	I	L	C	H	I	L	R	G	E	P	V	I	R	E	R	E	Q	D	E	L	H	T	F	T	D	T	M	L	P	G	C	F	H	L	L	D	E
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)													T	T	S	S	S				S	S	S	S																						T	T
	.	.	.	.	.	.	.	.	.	1060	.	.	.	.	.	.	.	.	.	1070	.	.	.	.	.	.	.	.	.	1080	.	.	.	.	.	.	.	.	.	1090	.	.	.	.	.	.	.	.	.	1100	.	.	.	.	.	.	.	.	.	1110	.	.	.	.	.	.	.	.	.	1120
Sequence	L	P	D	T	V	Y	R	V	C	D	L	I	M	T	A	I	K	R	N	G	A	D	Y	R	D	M	I	L	K	Q	V	V	N	Q	V	W	E	A	A	D	V	L	I	K	A	A	L	P	L	T	T	S	D	T	K	T	V	S	E	W	I	S	Q	M	A	T	L	P	Q	A
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)		G	G	G															S																										T		S			S	S		S	S		S	S										S
	.	.	.	.	.	.	.	.	.	1130	.	.	.	.	.	.	.	.	.	1140	.	.	.	.	.	.	.	.	.	1150	.	.	.	.	.	.	.	.	.	1160	.	.	.	.	.	.	.	.	.	1170	.	.	.	.	.	.	.	.	.	1180	.	.	.	.	.	.	.	.	.	1190
Sequence	S	N	L	A	T	R	I	L	L	L	T	L	L	F	E	E	L	K	L	P	C	A	W	V	V	E	S	S	G	I	L	N	V	L	I	K	L	L	E	V	V	Q	P	C	L	Q	A	A	K	E	Q	K	E	V	Q	T	P	K	W	I	T	P	V	L	L	L	I	D	F	Y
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																	S											T																								T						T	T
	.	.	.	.	.	.	.	.	.	1200	.	.	.	.	.	.	.	.	.	1210	.	.	.	.	.	.	.	.	.	1220	.	.	.	.	.	.	.	.	.	1230	.	.	.	.	.	.	.	.	.	1240	.	.	.	.	.	.	.	.	.	1250	.	.	.	.	.	.	.	.	.	1260
Sequence	E	K	T	A	I	S	S	K	R	R	A	Q	M	T	K	Y	L	Q	S	N	S	N	N	W	R	W	F	D	D	R	S	G	R	W	C	S	Y	S	A	S	N	N	S	T	I	D	S	A	W	K	S	G	E	T	S	V	R	F	T	A	G	R	R	R	Y	T	V	Q	F	T
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)															T	T	S		S	S	S								T	T	T	T																			T	T		S							T	T							T	T
	.	.	.	.	.	.	.	.	.	1270	.	.	.	.	.	.	.	.	.	1280	.	.	.	.	.	.	.	.	.	1290	.	.	.	.	.	.	.	.	.	1300	.	.	.	.	.	.	.	.	.	1310	.	.	.	.	.	.	.	.	.	1320	.	.	.	.	.	.	.	.	.	1330
Sequence	T	M	V	Q	V	N	E	E	T	G	N	R	R	P	V	M	L	T	L	L	I	L	I	Q	G	L	T	E	D	M	V	T	V	L	I	R	A	C	V	S	M	L	G	V	P	V	D	P	D	T	L	H	A	T	L	R	L	C	L	R	L	T	R	D	H	K	Y	A	M	M
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T	T					T	T	T																																			T	T																	T	T	S
	.	.	.	.	.	.	.	.	.	1340	.	.	.	.	.	.	.	.	.	1350	.	.	.	.	.	.	.	.	.	1360	.	.	.	.	.	.	.	.	.	1370	.	.	.	.	.	.	.	.	.	1380	.	.	.	.	.	.	.	.	.	1390	.	.	.	.	.	.	.	.	.	1400
Sequence	F	A	E	L	K	S	T	R	M	I	L	N	L	T	Q	S	S	G	F	N	G	F	T	P	L	V	T	L	L	L	R	H	I	I	E	D	P	C	T	L	R	H	T	M	E	K	V	V	R	S	A	A	T	S	G	A	G	S	T	T	S	G	V	V	S	G	S	L	G	S
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)				T	T									B	G	G	G			T	T																																	S					T	T				T	T		S	S	G	G
	.	.	.	.	.	.	.	.	.	1410	.	.	.	.	.	.	.	.	.	1420	.	.	.	.	.	.	.	.	.	1430	.	.	.	.	.	.	.	.	.	1440	.	.	.	.	.	.	.	.	.	1450	.	.	.	.	.	.	.	.	.	1460	.	.	.	.	.	.	.	.	.	1470
Sequence	R	E	I	N	Y	I	L	R	V	L	G	P	A	A	C	R	N	P	D	I	F	T	E	V	A	N	C	C	I	R	I	A	L	P	A	P	R	G	S	G	T	A	S	D	D	E	F	E	N	L	R	I	K	G	P	N	A	V	Q	L	V	K	T	T	P	L	K	P	S	P
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	G	B								T																											S	S	S		T	T	T										S	S	S	S				B
	.	.	.	.	.	.	.	.	.	1480	.	.	.	.	.	.	.	.	.	1490	.	.	.	.	.	.	.	.	.	1500	.	.	.	.	.	.	.	.	.	1510	.	.	.	.	.	.	.	.	.	1520	.	.	.	.	.	.	.	.	.	1530	.	.	.	.	.	.	.	.	.	1540
Sequence	L	P	V	I	P	D	T	I	K	E	V	I	Y	D	M	L	N	A	L	A	S	K	P	L	M	P	T	S	T	I	L	R	L	L	A	E	L	V	R	S	Y	V	G	I	A	T	L	I	A	N	Y	S	Y	T	V	G	Q	S	E	L	I	K	E	D	C	S	V	L	A	F
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																							B	S	S																											B			T	T	S	S	T	T			S			B
	.	.	.	.	.	.	.	.	.	1550	.	.	.	.	.	.	.	.	.	1560	.	.	.	.	.	.	.	.	.	1570	.	.	.	.	.	.	.	.	.	1580	.	.	.	.	.	.	.	.	.	1590	.	.	.	.	.	.	.	.	.	1600	.	.	.	.	.	.	.	.	.	1610
Sequence	V	L	D	H	L	L	P	H	T	Q	N	A	E	D	K	D	T	P	A	L	A	R	L	F	L	A	S	L	A	A	A	G	S	G	T	D	A	Q	V	A	L	V	N	E	V	K	A	A	L	G	R	A	L	A	M	A	E	S	T	E	K	H	A	R	L	Q	A	V	M	C
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)				T	T	S	S			S	S		S	S	T	T															S			T	T																				S		S	S
	.	.	.	.	.	.	.	.	.	1620	.	.	.	.	.	.	.	.	.	1630	.	.	.	.	.	.	.	.	.	1640	.	.	.	.	.	.	.	.	.	1650	.	.	.	.	.	.	.	.	.	1660	.	.	.	.	.	.	.	.	.	1670	.	.	.	.	.	.	.	.	.	1680
Sequence	I	I	S	T	I	M	E	N	N	I	I	R	L	F	L	K	K	G	L	V	N	D	L	A	R	V	P	H	S	L	D	L	S	S	P	N	M	A	N	T	V	N	A	A	L	K	P	L	E	T	L	S	R	I	V	N	Q	L	S	S	I	P	T	A	L	T	R	W	T	E
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																	T	T							T	G	G	G	G	S		T	T		T	T																							T	T	S
	.	.	.	.	.	.	.	.	.	1690	.	.	.	.	.	.	.	.	.	1700	.	.	.	.	.	.	.	.	.	1710	.	.	.	.	.	.	.	.	.	1720	.	.	.	.	.	.	.	.	.	1730	.	.	.	.	.	.	.	.	.	1740	.	.	.	.	.	.	.	.	.	1750
Sequence	E	C	K	V	L	D	A	E	S	M	H	D	C	V	S	V	V	K	V	S	I	V	N	H	L	E	F	L	R	D	E	E	L	E	E	R	R	E	K	R	R	K	Q	L	L	L	D	H	E	A	L	S	C	L	L	V	L	L	F	V	D	E	P	K	L	N	T	S	R	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)							T	T																																						S										G	G	G	T	S			S	S	S
	.	.	.	.	.	.	.	.	.	1760	.	.	.	.	.	.	.	.	.	1770	.	.	.	.	.	.	.	.	.	1780	.	.	.	.	.	.	.	.	.	1790	.	.	.	.	.	.	.	.	.	1800	.	.	.	.	.	.	.	.	.	1810	.	.	.	.	.	.	.	.	.	1820
Sequence	H	R	V	L	R	N	L	C	Y	H	A	Q	T	R	H	W	V	I	R	S	L	L	S	I	L	Q	R	S	S	S	W	L	S	V	S	M	D	A	A	L	G	C	R	T	N	I	F	Q	I	Q	T	V	H	I	H	P	Q	A	A	P	V	V	C	R	H	V	L	D	T	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)								T	T	S																														T	T					S										T	T	T
	.	.	.	.	.	.	.	.	.	1830	.	.	.	.	.	.	.	.	.	1840	.	.	.	.	.	.	.	.	.	1850	.	.	.	.	.	.	.	.	.	1860	.	.	.	.	.	.	.	.	.	1870	.	.	.	.	.	.	.	.	.	1880	.	.	.	.	.	.	.	.	.	1890
Sequence	I	Q	L	A	K	V	D	F	W	D	L	L	V	K	L	D	N	M	E	A	S	P	L	G	Q	L	M	N	M	L	S	H	P	V	I	R	R	S	S	L	L	T	E	K	L	L	R	L	L	S	L	I	S	I	G	L	T	E	N	Q	L	Q	L	S	V	E	V	L	T	S
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																					S	T							G	G	G	S																					T
	.	.	.	.	.	.	.	.	.	1900	.	.	.	.	.	.	.	.	.	1910	.	.	.	.	.	.	.	.	.	1920	.	.	.	.	.	.	.	.	.	1930	.	.	.	.	.	.	.	.	.	1940	.	.	.	.	.	.	.	.	.	1950	.	.	.	.	.	.	.	.	.	1960
Sequence	E	E	G	L	E	D	A	A	N	V	L	L	Q	L	S	R	G	D	S	G	T	R	D	T	V	L	K	L	L	L	N	G	A	R	H	L	G	Y	T	L	C	K	Q	I	G	T	L	L	A	E	L	R	E	Y	N	L	E	E	L	Q	L	P	S	M	S	M	L	T	S	K
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																T	T																																													G	G	G					S	T
	.	.	.	.	.	.	.	.	.	1970	.	.	.	.	.	.	.	.	.	1980	.	.	.	.	.	.	.	.	.	1990	.	.	.	.	.	.	.	.	.	2000	.	.	.	.	.	.	.	.	.	2010	.	.	.	.	.	.	.	.	.	2020	.	.	.	.	.	.	.	.	.	2030
Sequence	T	S	T	Q	K	F	F	L	R	V	L	Q	V	I	I	Q	L	R	D	L	S	L	D	E	L	W	D	M	L	G	E	C	L	K	E	L	E	E	S	H	D	Q	H	A	V	L	V	L	Q	P	A	V	E	A	F	F	L	V	H	A	T	E	Q	K	F	L	R	F	A	E
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T																																					T	T	T		S	G	G	G	G	G	G											S	S
	.	.	.	.	.	.	.	.	.	2040	.	.	.	.	.	.	.	.	.	2050	.	.	.	.	.	.	.	.	.	2060	.	.	.	.	.	.	.	.	.	2070	.	.	.	.	.	.	.	.	.	2080	.	.	.	.	.	.	.	.	.	2090	.	.	.	.	.	.	.	.	.	2100
Sequence	T	H	R	T	V	L	N	Q	I	L	R	Q	S	T	T	H	L	A	D	G	P	F	A	V	L	V	D	Y	I	R	V	L	D	F	D	V	K	R	K	Y	F	R	Q	E	L	E	R	L	D	E	G	L	R	K	E	D	M	A	V	H	V	R	R	D	H	V	F	E	D	S
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)		T													S		T	T	T	S	G	G	G	G	G	G	S		G	G	G	S																	T	T	T	S											T	T	T
	.	.	.	.	.	.	.	.	.	2110	.	.	.	.	.	.	.	.	.	2120	.	.	.	.	.	.	.	.	.	2130	.	.	.	.	.	.	.	.	.	2140	.	.	.	.	.	.	.	.	.	2150	.	.	.	.	.	.	.	.	.	2160	.	.	.	.	.	.	.	.	.	2170
Sequence	Y	R	E	L	H	R	K	S	P	E	E	M	K	N	R	L	Y	I	V	F	E	G	E	E	G	Q	D	A	G	G	L	L	R	E	W	Y	M	I	I	S	R	E	M	F	N	P	M	Y	A	L	F	R	T	S	P	G	D	R	V	T	Y	T	I	N	P	S	S	H	C	N
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)					T	T	S						T	S							T	T																					T	T		T	T	T	T						T	T	T	S	S	S	B				T	T	G	G	G	S
	.	.	.	.	.	.	.	.	.	2180	.	.	.	.	.	.	.	.	.	2190	.	.	.	.	.	.	.	.	.	2200	.	.	.	.	.	.	.	.	.	2210	.	.	.	.	.	.	.	.	.	2220	.	.	.	.	.	.	.	.	.	2230	.	.	.	.	.	.	.	.	.	2240
Sequence	P	N	H	L	S	Y	F	K	F	V	G	R	I	V	A	K	A	V	Y	D	N	R	L	L	E	C	Y	F	T	R	S	F	Y	K	H	I	L	G	K	S	V	R	Y	T	D	M	E	S	E	D	Y	H	F	Y	Q	G	L	V	Y	L	L	E	N	D	V	S	T	L	G	Y
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T	T																			T							B										T					G	G	G																T	T	S		G	G	G	T	S	S
	.	.	.	.	.	.	.	.	.	2250	.	.	.	.	.	.	.	.	.	2260	.	.	.	.	.	.	.	.	.	2270	.	.	.	.	.	.	.	.	.	2280	.	.	.	.	.	.	.	.	.	2290	.	.	.	.	.	.	.	.	.	2300	.	.	.	.	.	.	.	.	.	2310
Sequence	D	L	T	F	S	T	E	V	Q	E	F	G	V	C	E	V	R	D	L	K	V	T	E	E	N	K	K	E	Y	V	H	L	V	C	Q	M	R	M	T	G	A	I	R	K	Q	L	A	A	F	L	E	G	F	Y	E	I	I	P	K	R	L	I	S	I	F	T	E	Q	E	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)				S							T	T											T	T	T															G	G	G															S						T	T	S
	.	.	.	.	.	.	.	.	.	2320	.	.	.	.	.	.	.	.	.	2330	.	.	.	.	.	.	.	.	.	2340	.	.	.	.	.	.	.	.	.	2350	.	.	.	.	.	.	.	.	.	2360	.	.	.	.	.	.	.	.	.	2370	.	.	.	.	.	.	.	.	.	2380
Sequence	E	L	L	I	S	G	L	P	T	I	D	I	D	D	L	K	S	N	T	E	Y	H	K	Y	Q	S	N	S	I	Q	I	Q	W	F	W	R	A	L	R	S	F	D	Q	A	D	R	A	K	F	L	Q	F	V	T	G	T	S	K	V	P	L	Q	G	F	A	A	L	E	G	M
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)					T													T				S	S	S		T	T														S														S						T	T		G	G	G				T
	.	.	.	.	.	.	.	.	.	2390	.	.	.	.	.	.	.	.	.	2400	.	.	.	.	.	.	.	.	.	2410	.	.	.	.	.	.	.	.	.	2420	.	.	.	.	.	.	.
Sequence	N	G	I	Q	K	F	Q	I	H	R	D	D	R	S	T	D	R	L	P	S	A	H	T	C	F	N	Q	L	D	L	P	A	Y	E	S	F	E	K	L	R	H	M	L	L	L	A	I
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T												S		T	T	S						T	T	T	T								S