PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c6qfbB_

Fold library id	PDB Header	Molecule	Title
c6qfbB_	3.25	PDB header: lyase	Chain: B: PDB Molecule: atp-citrate synthase;

Links to external resources
Added to library: Sat Apr 13 08:38:35 2019

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence S A K A I S E Q T G K E L L Y K F I C T T S A I Q N R F K Y A R V T P D T D W A R L L Q D H P W L L S Q N L V V K P D Q L I K R R G K L G L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S
B
S T T
T T
G G G G T S
S S
S S T G G G T

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence V G V N L T L D G V K S W L K P R L G Q E A T V G K A T G F L K N F L I E P F V P H S Q A E E F Y V C I Y A T R E G D Y V L F H H E G G V D

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T T T T
T T
G G G T T S S
S S

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence V G D V D A K A Q K L L V G V D E K L N P E D I K K H L L V H A P E D K K E I L A S F I S G L F N F Y E D L Y F T Y L E I N P L V V T K D G

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S B
S S
T T T T S
G G G T T T T

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240 . . . . . . . . . 250 . . . . . . . . . 260 . . . . . . . . . 270 . . . . . . . . . 280

Sequence V Y V L D L A A K V D A T A D Y I C K V K W G D I E F P P P F G R E A Y P E E A Y I A D L D A K S G A S L K L T L L N P K G R I W T M V A G

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
G G G
S
T T
T S S S S
T T
S
B S

. . . . . . . . . 290 . . . . . . . . . 300 . . . . . . . . . 310 . . . . . . . . . 320 . . . . . . . . . 330 . . . . . . . . . 340 . . . . . . . . . 350

Sequence G G A S V V Y S D T I C D L G G V N E L A N Y G E Y S G A P S E Q Q T Y D Y A K T I L S L M T R E K H P D G K I L I I G G S I A N F T N V A

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T G G G G B
S
T S S
T T
B
B
S S S

. . . . . . . . . 360 . . . . . . . . . 370 . . . . . . . . . 380 . . . . . . . . . 390 . . . . . . . . . 400 . . . . . . . . . 410 . . . . . . . . . 420

Sequence A T F K G I V R A I R D Y Q G P L K E H E V T I F V R R G G P N Y Q E G L R V M G E V G K T T G I P I H V F G T E T H M T A I V G M A L G H

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T T
B S T T
T T S
T T T S

. . . . . . . . . 430 . . . . . . . . . 440 . . . . . . . . . 450 . . . . . . . . . 460 . . . . . . . . . 470 . . . . . . . . . 480 . . . . . . . . . 490

Sequence R P I P K S T T L F S R H T K A I V W G M Q T R A V Q G M L D F D Y V C S R D E P S V A A M V Y P F T G D H K Q K F Y W G H K E I L I P V F

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S
S
T T
S
T T
S S
S
T T S
S T T

. . . . . . . . . 500 . . . . . . . . . 510 . . . . . . . . . 520 . . . . . . . . . 530 . . . . . . . . . 540 . . . . . . . . . 550 . . . . . . . . . 560

Sequence K N M A D A M R K H P E V D V L I N F A S L R S A Y D S T M E T M N Y A Q I R T I A I I A E G I P E A L T R K L I K K A D Q K G V T I I G P

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S
T T
T T
T T
S
T
S

. . . . . . . . . 570 . . . . . . . . . 580 . . . . . . . . . 590 . . . . . . . . . 600 . . . . . . . . . 610 . . . . . . . . . 620 . . . . . . . . . 630

Sequence A T V G G I K P G C F K I G N T G G M L D N I L A S K L Y R P G S V A Y V S R S G G M S N E L N N I I S R T T D G V Y E G V A I G G D R Y P

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S
T T T
T T T T
S T T
S S
S S
S S
S S S S

. . . . . . . . . 640 . . . . . . . . . 650 . . . . . . . . . 660 . . . . . . . . . 670 . . . . . . . . . 680 . . . . . . . . . 690 . . . . . . . . . 700

Sequence G S T F M D H V L R Y Q D T P G V K M I V V L G E I G G T E E Y K I C R G I K E G R L T K P I V C W C I G T C A T M F S S E V Q F G H A G A

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S S
T
T T
S S S S T T T T S
S
S
S

. . . . . . . . . 710 . . . . . . . . . 720 . . . . . . . . . 730 . . . . . . . . . 740 . . . . . . . . . 750 . . . . . . . . . 760 . . . . . . . . . 770

Sequence C A N Q A S E T A V A K N Q A L K E A G V F V P R S F D E L G E I I Q S V Y E D L V A N G V I V P A Q E V P P P T V P M D Y S W A R E L G L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S S
S T
B
S S G G G T T S
T T

. . . . . . . . . 780 . . . . . . . . . 790 . . . . . . . . . 800 . . . . . . . . . 810 . . . . . . . . . 820 . . . . . . . . . 830 . . . . . . . . . 840

Sequence I R K P A S F M T S I C D E R G Q E L I Y A G M P I T E V F K E E M G I G G V L G L L W F Q K R L P K Y S C Q F I E M C L M V T A D H G P A

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S
S T T S S S
T T T T
S
S S
S S

. . . . . . . . . 850 . . . . . . . . . 860 . . . . . . . . . 870 . . . . . . . . . 880 . . . . . . . . . 890 . . . . . . . . . 900 . . . . . . . . . 910

Sequence V S G A H N T I I C A R A G K D L V S S L T S G L L T I G D R F G G A L D A A A K M F S K A F D S G I I P M E F V N K M K K E G K L I M G I

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S T T
T T B T T T B S
T T
T
T T B

. . . . . . . . . 920 . . . . . . . . . 930 . . . . . . . . . 940 . . . . . . . . . 950 . . . . . . . . . 960 . . . . . . . . . 970 . . . . . . . . . 980

Sequence G H R V K S I N N P D M R V Q I L K D Y V R Q H F P A T P L L D Y A L E V E K I T T S K K P N L I L N V D G L I G V A F V D M L R N C G S F

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S
S S S
S
T T S T T
B
S S S S

. . . . . . . . . 990 . . . . . . . . . 1000 . . . . . . . . . 1010 . . . . . . . . . 1020 . . . . . . . . . 1030 . . . . .

Sequence T R E E A D E Y I D I G A L N G I F V L G R S M G F I G H Y L D Q K R L K Q G L Y R H P W D D I S Y V L P E H

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T T
G G G

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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Phyre2 is part of Genome3D

	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	S	A	K	A	I	S	E	Q	T	G	K	E	L	L	Y	K	F	I	C	T	T	S	A	I	Q	N	R	F	K	Y	A	R	V	T	P	D	T	D	W	A	R	L	L	Q	D	H	P	W	L	L	S	Q	N	L	V	V	K	P	D	Q	L	I	K	R	R	G	K	L	G	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																					S	S		B		S	T	T							T	T											G	G	G	G	T	S								S	S		S	S	T	G	G	G	T
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	V	G	V	N	L	T	L	D	G	V	K	S	W	L	K	P	R	L	G	Q	E	A	T	V	G	K	A	T	G	F	L	K	N	F	L	I	E	P	F	V	P	H	S	Q	A	E	E	F	Y	V	C	I	Y	A	T	R	E	G	D	Y	V	L	F	H	H	E	G	G	V	D
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)															T	T	T	T	T						T	T																		G	G	G										T	T								S	S		S	S
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	V	G	D	V	D	A	K	A	Q	K	L	L	V	G	V	D	E	K	L	N	P	E	D	I	K	K	H	L	L	V	H	A	P	E	D	K	K	E	I	L	A	S	F	I	S	G	L	F	N	F	Y	E	D	L	Y	F	T	Y	L	E	I	N	P	L	V	V	T	K	D	G
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)								S	B						S	S												T	T	T	T	S		G	G	G																		T	T													T	T
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280
Sequence	V	Y	V	L	D	L	A	A	K	V	D	A	T	A	D	Y	I	C	K	V	K	W	G	D	I	E	F	P	P	P	F	G	R	E	A	Y	P	E	E	A	Y	I	A	D	L	D	A	K	S	G	A	S	L	K	L	T	L	L	N	P	K	G	R	I	W	T	M	V	A	G
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)												G	G	G										S							T	T																T	S	S	S							S		T	T		S						B	S
	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350
Sequence	G	G	A	S	V	V	Y	S	D	T	I	C	D	L	G	G	V	N	E	L	A	N	Y	G	E	Y	S	G	A	P	S	E	Q	Q	T	Y	D	Y	A	K	T	I	L	S	L	M	T	R	E	K	H	P	D	G	K	I	L	I	I	G	G	S	I	A	N	F	T	N	V	A
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)														T	T	G	G	G	G	B								S																			T	S	S			T	T								B		B		S	S	S
	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence	A	T	F	K	G	I	V	R	A	I	R	D	Y	Q	G	P	L	K	E	H	E	V	T	I	F	V	R	R	G	G	P	N	Y	Q	E	G	L	R	V	M	G	E	V	G	K	T	T	G	I	P	I	H	V	F	G	T	E	T	H	M	T	A	I	V	G	M	A	L	G	H
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)													T							T	T								B	S	T	T																								T	T	S		T	T								T	S
	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490
Sequence	R	P	I	P	K	S	T	T	L	F	S	R	H	T	K	A	I	V	W	G	M	Q	T	R	A	V	Q	G	M	L	D	F	D	Y	V	C	S	R	D	E	P	S	V	A	A	M	V	Y	P	F	T	G	D	H	K	Q	K	F	Y	W	G	H	K	E	I	L	I	P	V	F
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	S						S					T	T							S																T	T		S	S		S							T	T	S		S								T	T
	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560
Sequence	K	N	M	A	D	A	M	R	K	H	P	E	V	D	V	L	I	N	F	A	S	L	R	S	A	Y	D	S	T	M	E	T	M	N	Y	A	Q	I	R	T	I	A	I	I	A	E	G	I	P	E	A	L	T	R	K	L	I	K	K	A	D	Q	K	G	V	T	I	I	G	P
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	S										T	T																					T	T		T	T									S																		T						S
	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630
Sequence	A	T	V	G	G	I	K	P	G	C	F	K	I	G	N	T	G	G	M	L	D	N	I	L	A	S	K	L	Y	R	P	G	S	V	A	Y	V	S	R	S	G	G	M	S	N	E	L	N	N	I	I	S	R	T	T	D	G	V	Y	E	G	V	A	I	G	G	D	R	Y	P
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	S							T	T	T				T	T	T	T		S							T	T		S	S			S						S																S	S										S	S	S	S
	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.	.	660	.	.	.	.	.	.	.	.	.	670	.	.	.	.	.	.	.	.	.	680	.	.	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700
Sequence	G	S	T	F	M	D	H	V	L	R	Y	Q	D	T	P	G	V	K	M	I	V	V	L	G	E	I	G	G	T	E	E	Y	K	I	C	R	G	I	K	E	G	R	L	T	K	P	I	V	C	W	C	I	G	T	C	A	T	M	F	S	S	E	V	Q	F	G	H	A	G	A
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	S	S											T		T	T										S	S	S	S	T	T									T	T	S			S													S												S
	.	.	.	.	.	.	.	.	.	710	.	.	.	.	.	.	.	.	.	720	.	.	.	.	.	.	.	.	.	730	.	.	.	.	.	.	.	.	.	740	.	.	.	.	.	.	.	.	.	750	.	.	.	.	.	.	.	.	.	760	.	.	.	.	.	.	.	.	.	770
Sequence	C	A	N	Q	A	S	E	T	A	V	A	K	N	Q	A	L	K	E	A	G	V	F	V	P	R	S	F	D	E	L	G	E	I	I	Q	S	V	Y	E	D	L	V	A	N	G	V	I	V	P	A	Q	E	V	P	P	P	T	V	P	M	D	Y	S	W	A	R	E	L	G	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	S	S						S												T		B			S	S	G	G	G															T	T	S																						T	T
	.	.	.	.	.	.	.	.	.	780	.	.	.	.	.	.	.	.	.	790	.	.	.	.	.	.	.	.	.	800	.	.	.	.	.	.	.	.	.	810	.	.	.	.	.	.	.	.	.	820	.	.	.	.	.	.	.	.	.	830	.	.	.	.	.	.	.	.	.	840
Sequence	I	R	K	P	A	S	F	M	T	S	I	C	D	E	R	G	Q	E	L	I	Y	A	G	M	P	I	T	E	V	F	K	E	E	M	G	I	G	G	V	L	G	L	L	W	F	Q	K	R	L	P	K	Y	S	C	Q	F	I	E	M	C	L	M	V	T	A	D	H	G	P	A
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)						S					S			T	T	S	S	S				T	T									T	T														S																	S	S				S	S
	.	.	.	.	.	.	.	.	.	850	.	.	.	.	.	.	.	.	.	860	.	.	.	.	.	.	.	.	.	870	.	.	.	.	.	.	.	.	.	880	.	.	.	.	.	.	.	.	.	890	.	.	.	.	.	.	.	.	.	900	.	.	.	.	.	.	.	.	.	910
Sequence	V	S	G	A	H	N	T	I	I	C	A	R	A	G	K	D	L	V	S	S	L	T	S	G	L	L	T	I	G	D	R	F	G	G	A	L	D	A	A	A	K	M	F	S	K	A	F	D	S	G	I	I	P	M	E	F	V	N	K	M	K	K	E	G	K	L	I	M	G	I
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	S												T	T												T	T	B	T	T	T	B	S																T	T														T				T	T	B
	.	.	.	.	.	.	.	.	.	920	.	.	.	.	.	.	.	.	.	930	.	.	.	.	.	.	.	.	.	940	.	.	.	.	.	.	.	.	.	950	.	.	.	.	.	.	.	.	.	960	.	.	.	.	.	.	.	.	.	970	.	.	.	.	.	.	.	.	.	980
Sequence	G	H	R	V	K	S	I	N	N	P	D	M	R	V	Q	I	L	K	D	Y	V	R	Q	H	F	P	A	T	P	L	L	D	Y	A	L	E	V	E	K	I	T	T	S	K	K	P	N	L	I	L	N	V	D	G	L	I	G	V	A	F	V	D	M	L	R	N	C	G	S	F
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			S	S			S	S	S																	S																	T	T	S	T	T			B																	S	S	S	S
	.	.	.	.	.	.	.	.	.	990	.	.	.	.	.	.	.	.	.	1000	.	.	.	.	.	.	.	.	.	1010	.	.	.	.	.	.	.	.	.	1020	.	.	.	.	.	.	.	.	.	1030	.	.	.	.	.
Sequence	T	R	E	E	A	D	E	Y	I	D	I	G	A	L	N	G	I	F	V	L	G	R	S	M	G	F	I	G	H	Y	L	D	Q	K	R	L	K	Q	G	L	Y	R	H	P	W	D	D	I	S	Y	V	L	P	E	H
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)												T																								T	T								G	G	G