PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c6m49B_

Fold library id	PDB Header	Molecule	Title
c6m49B_	3.70	PDB header: membrane protein	Chain: B: PDB Molecule: sterol regulatory element-binding protein cleavage-

Links to external resources
Added to library: Sat Jan 23 09:00:41 2021

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence E R L R E K I S R A F Y N H G L L C A S Y P I P I I L F T G F C I L A C C Y P L L K L V A E L I P L V T T Y I I L F A Y I Y F S T R K I D M

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T
S
T T T T T

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence V K S K W G L A L A A V V T V L S S L L M S V G L C T L F G L T P T L N G G E I F P Y L V V V I G L E N V L V L T K S V V S T P V D L E V K

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T
T
S
S T S
S S S
S S

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence L R I A Q G L S S E S W S I M K N M A T E L G I I L I G Y F T L V P A I Q E F C L F A V V G L V S D F F L Q M L F F T T V L S I D I R R M E

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T T S

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . .

Sequence L A R L A Q R L I M A G T V V W I G I L V Y T D P A G L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T T

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	E	R	L	R	E	K	I	S	R	A	F	Y	N	H	G	L	L	C	A	S	Y	P	I	P	I	I	L	F	T	G	F	C	I	L	A	C	C	Y	P	L	L	K	L	V	A	E	L	I	P	L	V	T	T	Y	I	I	L	F	A	Y	I	Y	F	S	T	R	K	I	D	M
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)		T																				S																							T	T	T																				T	T
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	V	K	S	K	W	G	L	A	L	A	A	V	V	T	V	L	S	S	L	L	M	S	V	G	L	C	T	L	F	G	L	T	P	T	L	N	G	G	E	I	F	P	Y	L	V	V	V	I	G	L	E	N	V	L	V	L	T	K	S	V	V	S	T	P	V	D	L	E	V	K
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T	T			T																														S															S												T	S		S	S	S		S	S
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	L	R	I	A	Q	G	L	S	S	E	S	W	S	I	M	K	N	M	A	T	E	L	G	I	I	L	I	G	Y	F	T	L	V	P	A	I	Q	E	F	C	L	F	A	V	V	G	L	V	S	D	F	F	L	Q	M	L	F	F	T	T	V	L	S	I	D	I	R	R	M	E
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)									T	T																				T	S
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.
Sequence	L	A	R	L	A	Q	R	L	I	M	A	G	T	V	V	W	I	G	I	L	V	Y	T	D	P	A	G	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																								T	T	T