PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c6iz0A_

Fold library id	PDB Header	Molecule	Title
c6iz0A_	2.30	PDB header: membrane protein	Chain: A: PDB Molecule: trimeric intracellular cation channel type a;

Links to external resources
Added to library: Sat May 4 08:13:55 2019

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence Q L G E L A A A F A S V P V F P L F D A A Y F I V S V L Y L K Y E P G A V E M S R K S P F A S W L C A M L H C F G S Y I L A D L L L G E S P

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T
T T S T T
T T S
T

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence I H Y F S N N S S V I L A T A V W Y L I F F C P M N L F Y K C V S F L P V K L I F V A M K E V V R V R A I A A G V H H A H H Q Y H H G W F I

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T G G G G
G G G T S
T T

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence M M A T G W V K G S G V A L M S N F E Q L L R G V W R P E T N E I L H M S F P T K A S L Y G T V L F T L Q Q T H W L P V S E A N L V F F F T

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) G G G G G T T
T T
T T T S
T T
S
S

. . . . . . . . . 220 . . . .

Sequence M F M I V C K V F M T A T H

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	Q	L	G	E	L	A	A	A	F	A	S	V	P	V	F	P	L	F	D	A	A	Y	F	I	V	S	V	L	Y	L	K	Y	E	P	G	A	V	E	M	S	R	K	S	P	F	A	S	W	L	C	A	M	L	H	C	F	G	S	Y	I	L	A	D	L	L	L	G	E	S	P
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)										T	T				T	T																	S	T	T																															T	T	S		T
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	I	H	Y	F	S	N	N	S	S	V	I	L	A	T	A	V	W	Y	L	I	F	F	C	P	M	N	L	F	Y	K	C	V	S	F	L	P	V	K	L	I	F	V	A	M	K	E	V	V	R	V	R	A	I	A	A	G	V	H	H	A	H	H	Q	Y	H	H	G	W	F	I
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T	G	G	G	G																			G	G	G							T	S																															T	T
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	M	M	A	T	G	W	V	K	G	S	G	V	A	L	M	S	N	F	E	Q	L	L	R	G	V	W	R	P	E	T	N	E	I	L	H	M	S	F	P	T	K	A	S	L	Y	G	T	V	L	F	T	L	Q	Q	T	H	W	L	P	V	S	E	A	N	L	V	F	F	F	T
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)											G	G	G	G	G								T	T				T	T			T	T	T	S																				T	T		S		S
	.	.	.	.	.	.	.	.	.	220	.	.	.	.
Sequence	M	F	M	I	V	C	K	V	F	M	T	A	T	H
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)