PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c5lj5A_

Fold library id	PDB Header	Molecule	Title
c5lj5A_	3.80	PDB header: splicing	Chain: A: PDB Molecule: pre-mrna-splicing factor 8;

Links to external resources
Added to library: Thu Feb 9 19:50:31 2017

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence Y T P K A E M P P E H L R K I I N T H S D M A S K M Y N T D K K A F L G A L K Y L P H A I L K L L E N M P H P W E Q A K E V K V L Y H T S G

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
B
T S S
S S T T G G G T
T T
S
T T S

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence A I T F V N E T P R V I E P V Y T A Q W S A T W I A M R R E K R D R T H F K R M R F P P F D D D E P P L S Y E Q H I E N I E P L D P I N L P

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S
S S
S S S S
S S S
G G G S S S S S

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence L D S Q D D E Y V K D W L Y D S R P L E E D S K K V N G T S Y K K W S F D L P E M S N L Y R L S T P L R D E V T D K N Y Y Y L F D K K S F F

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T T S T T G G G T S S S S S S S
S S
S S B S
T T
T T T T
S
S G G G T T
S

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240 . . . . . . . . . 250 . . . . . . . . . 260 . . . . . . . . . 270 . . . . . . . . . 280

Sequence N G K A L N N A I P G G P K F E P L Y P R E E E E D Y N E F N S I D R V I F R V P I R S E Y K V A F P H L Y N S R P R S V R I P W Y N N P V

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T
T T S
S S
S
S S S
T T T
S S
T T S S S S
S

. . . . . . . . . 290 . . . . . . . . . 300 . . . . . . . . . 310 . . . . . . . . . 320 . . . . . . . . . 330 . . . . . . . . . 340 . . . . . . . . . 350

Sequence S C I I Q N D E E Y D T P A L F F D P S L E D F A P L L A E E E E L I L P N T K D A M S L Y H S P F P F N R T K G K M V R A Q D V A L A K K

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S S
S
S S
T T T T
S S
T T S
S
S T T
S S

. . . . . . . . . 360 . . . . . . . . . 370 . . . . . . . . . 380 . . . . . . . . . 390 . . . . . . . . . 400 . . . . . . . . . 410 . . . . . . . . . 420

Sequence W F L Q H P D E E Y P V K V K V S Y Q K L L K N Y V L N E L H P T L P T N H N K T K L L K S L K N T K Y F Q Q T T I D W V E A G L Q L C R Q

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S
S S
S
S S
S S S

. . . . . . . . . 430 . . . . . . . . . 440 . . . . . . . . . 450 . . . . . . . . . 460 . . . . . . . . . 470 . . . . . . . . . 480 . . . . . . . . . 490

Sequence G H N M L N L L I H R K G L T Y L H L D Y N F N L K P T K T L T T K E R K K S R L G N S F H L M R E L L K M M K L I V D T H V Q F R L G N V

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S
S
T T S
S S
T
T T T S

. . . . . . . . . 500 . . . . . . . . . 510 . . . . . . . . . 520 . . . . . . . . . 530 . . . . . . . . . 540 . . . . . . . . . 550 . . . . . . . . . 560

Sequence D A F Q L A D G I H Y I L N H I G Q L T G I Y R Y K Y K V M H Q I R A C K D L K H I I Y Y K F N K N L G K G P G C G F W Q P A W R V W L N F

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S
S T T T
T T T S S S
S
S

. . . . . . . . . 570 . . . . . . . . . 580 . . . . . . . . . 590 . . . . . . . . . 600 . . . . . . . . . 610 . . . . . . . . . 620 . . . . . . . . . 630

Sequence L R G T I P L L E R Y I G N L I T R Q F E G R S N E I V K T T T K Q R L D A Y Y D L E L R N S V M D D I L E M M P E S I R Q K K A R T I L Q

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S
S
T T S S T T S
S S

. . . . . . . . . 640 . . . . . . . . . 650 . . . . . . . . . 660 . . . . . . . . . 670 . . . . . . . . . 680 . . . . . . . . . 690 . . . . . . . . . 700

Sequence H L S E A W R C W K A N I P W D V P G M P A P I K K I I E R Y I K S K A D A W V S A A H Y N R E R I K R G A H V E K T M V K K N L G R L T R

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T
S S S
T

. . . . . . . . . 710 . . . . . . . . . 720 . . . . . . . . . 730 . . . . . . . . . 740 . . . . . . . . . 750 . . . . . . . . . 760 . . . . . . . . . 770

Sequence L W I K N E Q E R Q R Q I Q K N G P E I T P E E A T T I F S V M V E W L E S R S F S P I P F P P L T Y K N D T K I L V L A L E D L K D V Y A

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T
S S
T
T T
T T S

. . . . . . . . . 780 . . . . . . . . . 790 . . . . . . . . . 800 . . . . . . . . . 810 . . . . . . . . . 820 . . . . . . . . . 830 . . . . . . . . . 840

Sequence S K V R L N A S E R E E L A L I E E A Y D N P H D T L N R I K K Y L L T Q R V F K P V D I T M M E N Y Q N I S P V Y S V D P L E K I T D A Y

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S
S
T T S

. . . . . . . . . 850 . . . . . . . . . 860 . . . . . . . . . 870 . . . . . . . . . 880 . . . . . . . . . 890 . . . . . . . . . 900 . . . . . . . . . 910

Sequence L D Q Y L W Y E A D Q R K L F P N W I K P S D S E I P P L L V Y K W T Q G I N N L S E I W D V S R G Q S A V L L E T T L G E M A E K I D F T

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T
S
T T
T T S S S
S T T
S
S S
B T T T T T

. . . . . . . . . 920 . . . . . . . . . 930 . . . . . . . . . 940 . . . . . . . . . 950 . . . . . . . . . 960 . . . . . . . . . 970 . . . . . . . . . 980

Sequence L L N R L L R L I V D P N I A D Y I T A K N N V V I N F K D M S H V N K Y G L I R G L K F A S F I F Q Y Y G L V I D L L L L G Q E R A T D L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S
S
T T
S S
S S S T T

. . . . . . . . . 990 . . . . . . . . . 1000 . . . . . . . . . 1010 . . . . . . . . . 1020 . . . . . . . . . 1030 . . . . . . . . . 1040 . . . . . . . . . 1050

Sequence A G P A N N P N E F M Q F K S K E V E K A H P I R L Y T R Y L D R I Y M L F H F E E D E G E E L T D E Y L A E N P D P N F E N S I G Y N N R

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S S
T T
S
S S
S S
S
S S
S S T T

. . . . . . . . . 1060 . . . . . . . . . 1070 . . . . . . . . . 1080 . . . . . . . . . 1090 . . . . . . . . . 1100 . . . . . . . . . 1110 . . . . . . . . . 1120

Sequence K C W P K D S R M R L I R Q D V N L G R A V F W E I Q S R V P T S L T S I K W E N A F V S V Y S K N N P N L L F S M C G F E V R I L P R Q R

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T S
T T T S
T T S
T T T
B
T T T
S S S
T T T T T

. . . . . . . . . 1130 . . . . . . . . . 1140 . . . . . . . . . 1150 . . . . . . . . . 1160 . . . . . . . . . 1170 . . . . . . . . . 1180 . . . . . . . . . 1190

Sequence M E E V V S N D E G V W D L V D E R T K Q R T A K A Y L K V S E E E I K K F D S R I R G I L M A S G S T T F T K V A A K W N T S L I S L F T

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S S S
S S
T T T
S S
S S S

. . . . . . . . . 1200 . . . . . . . . . 1210 . . . . . . . . . 1220 . . . . . . . . . 1230 . . . . . . . . . 1240 . . . . . . . . . 1250 . . . . . . . . . 1260

Sequence Y F R E A I V A T E P L L D I L V K G E T R I Q N R V K L G L N S K M P T R F P P A V F Y T P K E L G G L G M I S A S H I L I P A S D L S W

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S S G G G T T
T T
T T T S
T S
G G G T S
S S
B

. . . . . . . . . 1270 . . . . . . . . . 1280 . . . . . . . . . 1290 . . . . . . . . . 1300 . . . . . . . . . 1310 . . . . . . . . . 1320 . . . . . . . . . 1330

Sequence S K Q T D T G I T H F R A G M T H E D E K L I P T I F R Y I T T W E N E F L D S Q R V W A E Y A T K R Q E A I Q Q N R R L A F E E L E G S W

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S S S
S B
S
S S
G G G G S
T
T T T S T T S S

. . . . . . . . . 1340 . . . . . . . . . 1350 . . . . . . . . . 1360 . . . . . . . . . 1370 . . . . . . . . . 1380 . . . . . . . . . 1390 . . . . . . . . . 1400

Sequence D R G I P R I S T L F Q R D R H T L A Y D R G H R I R R E F K Q Y S L E R N S P F W W T N S H H D G K L W N L N A Y R T D V I Q A L G G I E

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S
B T T B G G G S S S T T T T
S
S S
T T
S
S
T T

. . . . . . . . . 1410 . . . . . . . . . 1420 . . . . . . . . . 1430 . . . . . . . . . 1440 . . . . . . . . . 1450 . . . . . . . . . 1460 . . . . . . . . . 1470

Sequence T I L E H T L F K G T G F N S W E G L F W E K A S G F E D S M Q F K K L T H A Q R T G L S Q I P N R R F T L W W S P T I N R A N V Y V G F L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S S G G G G T
S
S S S
S
T T
T T S S S
S S S
S S
T S
S S
S S

. . . . . . . . . 1480 . . . . . . . . . 1490 . . . . . . . . . 1500 . . . . . . . . . 1510 . . . . . . . . . 1520 . . . . . . . . . 1530 . . . . . . . . . 1540

Sequence V Q L D L T G I F L H G K I P T L K I S L I Q I F R A H L W Q K I H E S I V F D I C Q I L D G E L D V L Q I E S V T K E T V H P R K S Y K M

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T S S
S
T T T T T T T T T T
G G G G G
S

. . . . . . . . . 1550 . . . . . . . . . 1560 . . . . . . . . . 1570 . . . . . . . . . 1580 . . . . . . . . . 1590 . . . . . . . . . 1600 . . . . . . . . . 1610

Sequence N S S A A D I T M E S V H E W E V S K P S L L H E T N D S F K G L I T N K M W F D V Q L R Y G D Y D S H D I S R Y V R A K F L D Y T T D N V

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S S
S
S S S
S
S S
T T T
S S

. . . . . . . . . 1620 . . . . . . . . . 1630 . . . . . . . . . 1640 . . . . . . . . . 1650 . . . . . . . . . 1660 . . . . . . . . . 1670 . . . . . . . . . 1680

Sequence S M Y P S P T G V M I G I D L A Y N M Y D A Y G N W F N G L K P L I Q N S M R T I M K A N P A L Y V L R E R I R K G L Q I Y Q S S N Y A E L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S
S S S
T T T T
T T
T
T T S G G G

. . . . . . . . . 1690 . . . . . . . . . 1700 . . . . . . . . . 1710 . . . . . . . . . 1720 . . . . . . . . . 1730 . . . . . . . . . 1740 . . . . . . . . . 1750

Sequence F N N D I K L F V D D T N V Y R V T V H K T F E G N V A T K A I N G C I F T L N P K T G H L F L K I I H T S V W A G Q K R L S Q L A K W K T

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) G S S S
T T S S
B
S S
B
T T T
G G G G T T
S

. . . . . . . . . 1760 . . . . . . . . . 1770 . . . . . . . . . 1780 . . . . . . . . . 1790 . . . . . . . . . 1800 . . . . . . . . . 1810 . . . . . . . . . 1820

Sequence A E E V S A L V R S L P K E E Q P K Q I I V T R K A M L D P L E V H M L D F P N I A I R P T E L R L P F S A A M S I D K L S D V V M K A T E

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S
T T T
S S S G G G T T S
S S S
S
G G G G G T T S S
S S

. . . . . . . . . 1830 . . . . . . . . . 1840 . . . . . . . . . 1850 . . . . . . . . . 1860 . . . . . . . . . 1870 . . . . . . . . . 1880 . . . . . . . . . 1890

Sequence P Q M V L F N I Y D D W L D R I S S Y T A F S R L T L L L R A L K T N E E S A K M I L L S D P T I T I K S Y H L W P S F T D E Q W I T I E S

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S S S
T T T S
T S S T T S
B
T T
S S B

. . . . . . . . . 1900 . . . . . . . . . 1910 . . . . . . . . . 1920 . . . . . . . . . 1930 . . . . . . . . . 1940 . . . . . . . . . 1950 . . . . . . . . . 1960

Sequence Q M R D L I L T E Y G R K Y N V N I S A L T Q T E I K D I I L G N E W R K S A I A N T L L Y L R L K N I Y V S A D D F V E E Q N V Y V L P K

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T
G G G G G G G G G S
T T S

. . . . . . . . . 1970 . . . . . . . . . 1980 . . . . . . . . . 1990 . . . . . . . . . 2000 . . . . . . . . . 2010 . . . . . . . . . 2020 . . . . . . . . . 2030

Sequence N L L K K F I E I S D V K I Q V A A F I Y G M S A K D H P K V K E I K T V V L V P Q L G H V G S V Q I S N I P D I G D L P D T E G L E L L G

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T S
S S S
S S
T T
T T
T T S T T
T T

. . . . . . . . . 2040 . . . . . . . . . 2050 . . . . . . . . . 2060 . . . . . . . . . 2070 . . . . . . . . . 2080 . . . . . . . . . 2090 . . . . . . . . . 2100

Sequence W I H T Q T E E L K F M A A S E V A T H S K L F A D K K R D C I D I S I F S T P G S V S L S A Y N L T D E G Y Q W G E E N K D I M N V L S E

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S S
S S
T T T
T T
T T
S S
T T T

. . . . . . . . . 2110 . . . . . . . . . 2120 . . . . . . . . . 2130 . . . . . . . . . 2140 . . . . . . . . . 2150 . . . . . . . . . 2160 . . . . . . . .

Sequence G F E P T F S T H A Q L L L S D R I T G N F I I P S G N V W N Y T F M G T A F N Q E G D Y N F K Y G I P L E F Y N E M H R P V H F L Q F

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S
G G G
S S S
S S
B
S T T T T T
T T
T T
G G G
T T

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

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Accessibility Statement

Please cite: The Phyre2 web portal for protein modeling, prediction and analysis

Kelley LA et al. Nature Protocols 10, 845-858 (2015) [paper] [Citation link]

© Structural Bioinformatics Group,
Imperial College,
London
Michael Sternberg
Disclaimer

Terms and Conditions

	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	Y	T	P	K	A	E	M	P	P	E	H	L	R	K	I	I	N	T	H	S	D	M	A	S	K	M	Y	N	T	D	K	K	A	F	L	G	A	L	K	Y	L	P	H	A	I	L	K	L	L	E	N	M	P	H	P	W	E	Q	A	K	E	V	K	V	L	Y	H	T	S	G
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)						B													T	S	S			S	S	T	T											G	G	G											T				T	T		S										T	T	S
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	A	I	T	F	V	N	E	T	P	R	V	I	E	P	V	Y	T	A	Q	W	S	A	T	W	I	A	M	R	R	E	K	R	D	R	T	H	F	K	R	M	R	F	P	P	F	D	D	D	E	P	P	L	S	Y	E	Q	H	I	E	N	I	E	P	L	D	P	I	N	L	P
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	S																																		S	S						S	S	S	S		S	S	S					G	G	G	S	S	S	S	S
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	L	D	S	Q	D	D	E	Y	V	K	D	W	L	Y	D	S	R	P	L	E	E	D	S	K	K	V	N	G	T	S	Y	K	K	W	S	F	D	L	P	E	M	S	N	L	Y	R	L	S	T	P	L	R	D	E	V	T	D	K	N	Y	Y	Y	L	F	D	K	K	S	F	F
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			T	T	T	S	T	T	G	G	G	T	S	S	S	S	S	S	S		S	S		S	S	B	S		T	T																		T	T	T	T					S		S	G	G	G	T	T		S
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280
Sequence	N	G	K	A	L	N	N	A	I	P	G	G	P	K	F	E	P	L	Y	P	R	E	E	E	E	D	Y	N	E	F	N	S	I	D	R	V	I	F	R	V	P	I	R	S	E	Y	K	V	A	F	P	H	L	Y	N	S	R	P	R	S	V	R	I	P	W	Y	N	N	P	V
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)						T				T	T	S						S	S								S		S	S	S		T	T	T				S	S								T	T	S					S	S	S			S
	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350
Sequence	S	C	I	I	Q	N	D	E	E	Y	D	T	P	A	L	F	F	D	P	S	L	E	D	F	A	P	L	L	A	E	E	E	E	L	I	L	P	N	T	K	D	A	M	S	L	Y	H	S	P	F	P	F	N	R	T	K	G	K	M	V	R	A	Q	D	V	A	L	A	K	K
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)						S	S	S			S				S	S											T	T	T	T				S	S		T	T										S							S							S	T	T			S	S
	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence	W	F	L	Q	H	P	D	E	E	Y	P	V	K	V	K	V	S	Y	Q	K	L	L	K	N	Y	V	L	N	E	L	H	P	T	L	P	T	N	H	N	K	T	K	L	L	K	S	L	K	N	T	K	Y	F	Q	Q	T	T	I	D	W	V	E	A	G	L	Q	L	C	R	Q
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)				S				S	S																						S						S	S												S	S	S
	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490
Sequence	G	H	N	M	L	N	L	L	I	H	R	K	G	L	T	Y	L	H	L	D	Y	N	F	N	L	K	P	T	K	T	L	T	T	K	E	R	K	K	S	R	L	G	N	S	F	H	L	M	R	E	L	L	K	M	M	K	L	I	V	D	T	H	V	Q	F	R	L	G	N	V
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)													S			S					T	T	S					S	S										T																												T	T	T	S
	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560
Sequence	D	A	F	Q	L	A	D	G	I	H	Y	I	L	N	H	I	G	Q	L	T	G	I	Y	R	Y	K	Y	K	V	M	H	Q	I	R	A	C	K	D	L	K	H	I	I	Y	Y	K	F	N	K	N	L	G	K	G	P	G	C	G	F	W	Q	P	A	W	R	V	W	L	N	F
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																				S		S	T	T	T		T	T																				T	S	S	S		S		S
	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630
Sequence	L	R	G	T	I	P	L	L	E	R	Y	I	G	N	L	I	T	R	Q	F	E	G	R	S	N	E	I	V	K	T	T	T	K	Q	R	L	D	A	Y	Y	D	L	E	L	R	N	S	V	M	D	D	I	L	E	M	M	P	E	S	I	R	Q	K	K	A	R	T	I	L	Q
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																					S			S						T	T	S	S	T	T																					S			S	S
	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.	.	660	.	.	.	.	.	.	.	.	.	670	.	.	.	.	.	.	.	.	.	680	.	.	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700
Sequence	H	L	S	E	A	W	R	C	W	K	A	N	I	P	W	D	V	P	G	M	P	A	P	I	K	K	I	I	E	R	Y	I	K	S	K	A	D	A	W	V	S	A	A	H	Y	N	R	E	R	I	K	R	G	A	H	V	E	K	T	M	V	K	K	N	L	G	R	L	T	R
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)												T						S	S	S																																	T
	.	.	.	.	.	.	.	.	.	710	.	.	.	.	.	.	.	.	.	720	.	.	.	.	.	.	.	.	.	730	.	.	.	.	.	.	.	.	.	740	.	.	.	.	.	.	.	.	.	750	.	.	.	.	.	.	.	.	.	760	.	.	.	.	.	.	.	.	.	770
Sequence	L	W	I	K	N	E	Q	E	R	Q	R	Q	I	Q	K	N	G	P	E	I	T	P	E	E	A	T	T	I	F	S	V	M	V	E	W	L	E	S	R	S	F	S	P	I	P	F	P	P	L	T	Y	K	N	D	T	K	I	L	V	L	A	L	E	D	L	K	D	V	Y	A
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																T			S	S																				T									T	T		T	T																	S
	.	.	.	.	.	.	.	.	.	780	.	.	.	.	.	.	.	.	.	790	.	.	.	.	.	.	.	.	.	800	.	.	.	.	.	.	.	.	.	810	.	.	.	.	.	.	.	.	.	820	.	.	.	.	.	.	.	.	.	830	.	.	.	.	.	.	.	.	.	840
Sequence	S	K	V	R	L	N	A	S	E	R	E	E	L	A	L	I	E	E	A	Y	D	N	P	H	D	T	L	N	R	I	K	K	Y	L	L	T	Q	R	V	F	K	P	V	D	I	T	M	M	E	N	Y	Q	N	I	S	P	V	Y	S	V	D	P	L	E	K	I	T	D	A	Y
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	S		S																																																T	T	S
	.	.	.	.	.	.	.	.	.	850	.	.	.	.	.	.	.	.	.	860	.	.	.	.	.	.	.	.	.	870	.	.	.	.	.	.	.	.	.	880	.	.	.	.	.	.	.	.	.	890	.	.	.	.	.	.	.	.	.	900	.	.	.	.	.	.	.	.	.	910
Sequence	L	D	Q	Y	L	W	Y	E	A	D	Q	R	K	L	F	P	N	W	I	K	P	S	D	S	E	I	P	P	L	L	V	Y	K	W	T	Q	G	I	N	N	L	S	E	I	W	D	V	S	R	G	Q	S	A	V	L	L	E	T	T	L	G	E	M	A	E	K	I	D	F	T
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)													T		S		T	T			T	T	S	S	S																S	T	T		S			S	S												B	T	T	T	T	T
	.	.	.	.	.	.	.	.	.	920	.	.	.	.	.	.	.	.	.	930	.	.	.	.	.	.	.	.	.	940	.	.	.	.	.	.	.	.	.	950	.	.	.	.	.	.	.	.	.	960	.	.	.	.	.	.	.	.	.	970	.	.	.	.	.	.	.	.	.	980
Sequence	L	L	N	R	L	L	R	L	I	V	D	P	N	I	A	D	Y	I	T	A	K	N	N	V	V	I	N	F	K	D	M	S	H	V	N	K	Y	G	L	I	R	G	L	K	F	A	S	F	I	F	Q	Y	Y	G	L	V	I	D	L	L	L	L	G	Q	E	R	A	T	D	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)										S													S						T	T							S	S			S	S	S	T	T
	.	.	.	.	.	.	.	.	.	990	.	.	.	.	.	.	.	.	.	1000	.	.	.	.	.	.	.	.	.	1010	.	.	.	.	.	.	.	.	.	1020	.	.	.	.	.	.	.	.	.	1030	.	.	.	.	.	.	.	.	.	1040	.	.	.	.	.	.	.	.	.	1050
Sequence	A	G	P	A	N	N	P	N	E	F	M	Q	F	K	S	K	E	V	E	K	A	H	P	I	R	L	Y	T	R	Y	L	D	R	I	Y	M	L	F	H	F	E	E	D	E	G	E	E	L	T	D	E	Y	L	A	E	N	P	D	P	N	F	E	N	S	I	G	Y	N	N	R
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)				S	S	S				T	T			S								S	S								S	S																								S			S	S			S	S	T	T
	.	.	.	.	.	.	.	.	.	1060	.	.	.	.	.	.	.	.	.	1070	.	.	.	.	.	.	.	.	.	1080	.	.	.	.	.	.	.	.	.	1090	.	.	.	.	.	.	.	.	.	1100	.	.	.	.	.	.	.	.	.	1110	.	.	.	.	.	.	.	.	.	1120
Sequence	K	C	W	P	K	D	S	R	M	R	L	I	R	Q	D	V	N	L	G	R	A	V	F	W	E	I	Q	S	R	V	P	T	S	L	T	S	I	K	W	E	N	A	F	V	S	V	Y	S	K	N	N	P	N	L	L	F	S	M	C	G	F	E	V	R	I	L	P	R	Q	R
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T	T	S		T	T	T	S					T	T																S		T	T	T		B			T	T	T							S	S	S									T	T								T	T	T
	.	.	.	.	.	.	.	.	.	1130	.	.	.	.	.	.	.	.	.	1140	.	.	.	.	.	.	.	.	.	1150	.	.	.	.	.	.	.	.	.	1160	.	.	.	.	.	.	.	.	.	1170	.	.	.	.	.	.	.	.	.	1180	.	.	.	.	.	.	.	.	.	1190
Sequence	M	E	E	V	V	S	N	D	E	G	V	W	D	L	V	D	E	R	T	K	Q	R	T	A	K	A	Y	L	K	V	S	E	E	E	I	K	K	F	D	S	R	I	R	G	I	L	M	A	S	G	S	T	T	F	T	K	V	A	A	K	W	N	T	S	L	I	S	L	F	T
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	S	S	S						S	S							T	T	T																												S	S		S	S	S
	.	.	.	.	.	.	.	.	.	1200	.	.	.	.	.	.	.	.	.	1210	.	.	.	.	.	.	.	.	.	1220	.	.	.	.	.	.	.	.	.	1230	.	.	.	.	.	.	.	.	.	1240	.	.	.	.	.	.	.	.	.	1250	.	.	.	.	.	.	.	.	.	1260
Sequence	Y	F	R	E	A	I	V	A	T	E	P	L	L	D	I	L	V	K	G	E	T	R	I	Q	N	R	V	K	L	G	L	N	S	K	M	P	T	R	F	P	P	A	V	F	Y	T	P	K	E	L	G	G	L	G	M	I	S	A	S	H	I	L	I	P	A	S	D	L	S	W
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)		S	S	G	G	G	T	T																							T	T				T	T	T	S		T					S		G	G	G	T	S								S	S			B
	.	.	.	.	.	.	.	.	.	1270	.	.	.	.	.	.	.	.	.	1280	.	.	.	.	.	.	.	.	.	1290	.	.	.	.	.	.	.	.	.	1300	.	.	.	.	.	.	.	.	.	1310	.	.	.	.	.	.	.	.	.	1320	.	.	.	.	.	.	.	.	.	1330
Sequence	S	K	Q	T	D	T	G	I	T	H	F	R	A	G	M	T	H	E	D	E	K	L	I	P	T	I	F	R	Y	I	T	T	W	E	N	E	F	L	D	S	Q	R	V	W	A	E	Y	A	T	K	R	Q	E	A	I	Q	Q	N	R	R	L	A	F	E	E	L	E	G	S	W
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)		S	S	S						S	B				S				S	S						G	G	G	G	S																												T					T	T	T	S	T	T	S	S
	.	.	.	.	.	.	.	.	.	1340	.	.	.	.	.	.	.	.	.	1350	.	.	.	.	.	.	.	.	.	1360	.	.	.	.	.	.	.	.	.	1370	.	.	.	.	.	.	.	.	.	1380	.	.	.	.	.	.	.	.	.	1390	.	.	.	.	.	.	.	.	.	1400
Sequence	D	R	G	I	P	R	I	S	T	L	F	Q	R	D	R	H	T	L	A	Y	D	R	G	H	R	I	R	R	E	F	K	Q	Y	S	L	E	R	N	S	P	F	W	W	T	N	S	H	H	D	G	K	L	W	N	L	N	A	Y	R	T	D	V	I	Q	A	L	G	G	I	E
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	S		B	T	T	B	G	G	G	S	S	S	T	T					T	T			S													S	S			T	T		S									S														T	T
	.	.	.	.	.	.	.	.	.	1410	.	.	.	.	.	.	.	.	.	1420	.	.	.	.	.	.	.	.	.	1430	.	.	.	.	.	.	.	.	.	1440	.	.	.	.	.	.	.	.	.	1450	.	.	.	.	.	.	.	.	.	1460	.	.	.	.	.	.	.	.	.	1470
Sequence	T	I	L	E	H	T	L	F	K	G	T	G	F	N	S	W	E	G	L	F	W	E	K	A	S	G	F	E	D	S	M	Q	F	K	K	L	T	H	A	Q	R	T	G	L	S	Q	I	P	N	R	R	F	T	L	W	W	S	P	T	I	N	R	A	N	V	Y	V	G	F	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)						S	S	G	G	G	G	T		S		S	S	S				S							T	T		T	T	S	S	S			S	S	S		S	S												T					S		S	S		S	S
	.	.	.	.	.	.	.	.	.	1480	.	.	.	.	.	.	.	.	.	1490	.	.	.	.	.	.	.	.	.	1500	.	.	.	.	.	.	.	.	.	1510	.	.	.	.	.	.	.	.	.	1520	.	.	.	.	.	.	.	.	.	1530	.	.	.	.	.	.	.	.	.	1540
Sequence	V	Q	L	D	L	T	G	I	F	L	H	G	K	I	P	T	L	K	I	S	L	I	Q	I	F	R	A	H	L	W	Q	K	I	H	E	S	I	V	F	D	I	C	Q	I	L	D	G	E	L	D	V	L	Q	I	E	S	V	T	K	E	T	V	H	P	R	K	S	Y	K	M
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)				T	T	S	S					S													T	T	T	T																				T	T	T	T	T	T											G	G	G	G	G		S
	.	.	.	.	.	.	.	.	.	1550	.	.	.	.	.	.	.	.	.	1560	.	.	.	.	.	.	.	.	.	1570	.	.	.	.	.	.	.	.	.	1580	.	.	.	.	.	.	.	.	.	1590	.	.	.	.	.	.	.	.	.	1600	.	.	.	.	.	.	.	.	.	1610
Sequence	N	S	S	A	A	D	I	T	M	E	S	V	H	E	W	E	V	S	K	P	S	L	L	H	E	T	N	D	S	F	K	G	L	I	T	N	K	M	W	F	D	V	Q	L	R	Y	G	D	Y	D	S	H	D	I	S	R	Y	V	R	A	K	F	L	D	Y	T	T	D	N	V
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	S	S				S														S			S	S		S					S	S																	T	T	T																	S	S
	.	.	.	.	.	.	.	.	.	1620	.	.	.	.	.	.	.	.	.	1630	.	.	.	.	.	.	.	.	.	1640	.	.	.	.	.	.	.	.	.	1650	.	.	.	.	.	.	.	.	.	1660	.	.	.	.	.	.	.	.	.	1670	.	.	.	.	.	.	.	.	.	1680
Sequence	S	M	Y	P	S	P	T	G	V	M	I	G	I	D	L	A	Y	N	M	Y	D	A	Y	G	N	W	F	N	G	L	K	P	L	I	Q	N	S	M	R	T	I	M	K	A	N	P	A	L	Y	V	L	R	E	R	I	R	K	G	L	Q	I	Y	Q	S	S	N	Y	A	E	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)		S		S	S	S									T	T	T	T										T	T																															T					T	T	S	G	G	G
	.	.	.	.	.	.	.	.	.	1690	.	.	.	.	.	.	.	.	.	1700	.	.	.	.	.	.	.	.	.	1710	.	.	.	.	.	.	.	.	.	1720	.	.	.	.	.	.	.	.	.	1730	.	.	.	.	.	.	.	.	.	1740	.	.	.	.	.	.	.	.	.	1750
Sequence	F	N	N	D	I	K	L	F	V	D	D	T	N	V	Y	R	V	T	V	H	K	T	F	E	G	N	V	A	T	K	A	I	N	G	C	I	F	T	L	N	P	K	T	G	H	L	F	L	K	I	I	H	T	S	V	W	A	G	Q	K	R	L	S	Q	L	A	K	W	K	T
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	G	S	S	S								T	T	S	S						B		S	S			B														T	T	T										G	G	G	G	T	T			S
	.	.	.	.	.	.	.	.	.	1760	.	.	.	.	.	.	.	.	.	1770	.	.	.	.	.	.	.	.	.	1780	.	.	.	.	.	.	.	.	.	1790	.	.	.	.	.	.	.	.	.	1800	.	.	.	.	.	.	.	.	.	1810	.	.	.	.	.	.	.	.	.	1820
Sequence	A	E	E	V	S	A	L	V	R	S	L	P	K	E	E	Q	P	K	Q	I	I	V	T	R	K	A	M	L	D	P	L	E	V	H	M	L	D	F	P	N	I	A	I	R	P	T	E	L	R	L	P	F	S	A	A	M	S	I	D	K	L	S	D	V	V	M	K	A	T	E
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)											S		T	T	T			S					S	S	G	G	G								T	T	S		S	S	S						S				G	G	G	G	G	T	T	S									S		S	S
	.	.	.	.	.	.	.	.	.	1830	.	.	.	.	.	.	.	.	.	1840	.	.	.	.	.	.	.	.	.	1850	.	.	.	.	.	.	.	.	.	1860	.	.	.	.	.	.	.	.	.	1870	.	.	.	.	.	.	.	.	.	1880	.	.	.	.	.	.	.	.	.	1890
Sequence	P	Q	M	V	L	F	N	I	Y	D	D	W	L	D	R	I	S	S	Y	T	A	F	S	R	L	T	L	L	L	R	A	L	K	T	N	E	E	S	A	K	M	I	L	L	S	D	P	T	I	T	I	K	S	Y	H	L	W	P	S	F	T	D	E	Q	W	I	T	I	E	S
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)								S	S	S	S		T	T	T	S																												T	S	S	T	T	S		B		T	T		S	S	B
	.	.	.	.	.	.	.	.	.	1900	.	.	.	.	.	.	.	.	.	1910	.	.	.	.	.	.	.	.	.	1920	.	.	.	.	.	.	.	.	.	1930	.	.	.	.	.	.	.	.	.	1940	.	.	.	.	.	.	.	.	.	1950	.	.	.	.	.	.	.	.	.	1960
Sequence	Q	M	R	D	L	I	L	T	E	Y	G	R	K	Y	N	V	N	I	S	A	L	T	Q	T	E	I	K	D	I	I	L	G	N	E	W	R	K	S	A	I	A	N	T	L	L	Y	L	R	L	K	N	I	Y	V	S	A	D	D	F	V	E	E	Q	N	V	Y	V	L	P	K
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																															T											G	G	G	G	G	G	G	G	G	S										T	T	S
	.	.	.	.	.	.	.	.	.	1970	.	.	.	.	.	.	.	.	.	1980	.	.	.	.	.	.	.	.	.	1990	.	.	.	.	.	.	.	.	.	2000	.	.	.	.	.	.	.	.	.	2010	.	.	.	.	.	.	.	.	.	2020	.	.	.	.	.	.	.	.	.	2030
Sequence	N	L	L	K	K	F	I	E	I	S	D	V	K	I	Q	V	A	A	F	I	Y	G	M	S	A	K	D	H	P	K	V	K	E	I	K	T	V	V	L	V	P	Q	L	G	H	V	G	S	V	Q	I	S	N	I	P	D	I	G	D	L	P	D	T	E	G	L	E	L	L	G
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)									T	S		S	S	S												S	S		T	T																T	T											T	T	S	T	T		T	T
	.	.	.	.	.	.	.	.	.	2040	.	.	.	.	.	.	.	.	.	2050	.	.	.	.	.	.	.	.	.	2060	.	.	.	.	.	.	.	.	.	2070	.	.	.	.	.	.	.	.	.	2080	.	.	.	.	.	.	.	.	.	2090	.	.	.	.	.	.	.	.	.	2100
Sequence	W	I	H	T	Q	T	E	E	L	K	F	M	A	A	S	E	V	A	T	H	S	K	L	F	A	D	K	K	R	D	C	I	D	I	S	I	F	S	T	P	G	S	V	S	L	S	A	Y	N	L	T	D	E	G	Y	Q	W	G	E	E	N	K	D	I	M	N	V	L	S	E
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)						S	S			S	S														T	T	T		T	T										T	T																					S	S			T	T	T
	.	.	.	.	.	.	.	.	.	2110	.	.	.	.	.	.	.	.	.	2120	.	.	.	.	.	.	.	.	.	2130	.	.	.	.	.	.	.	.	.	2140	.	.	.	.	.	.	.	.	.	2150	.	.	.	.	.	.	.	.	.	2160	.	.	.	.	.	.	.	.
Sequence	G	F	E	P	T	F	S	T	H	A	Q	L	L	L	S	D	R	I	T	G	N	F	I	I	P	S	G	N	V	W	N	Y	T	F	M	G	T	A	F	N	Q	E	G	D	Y	N	F	K	Y	G	I	P	L	E	F	Y	N	E	M	H	R	P	V	H	F	L	Q	F
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	S			G	G	G										S	S	S								S	S				B		S	T	T	T	T	T			T	T													T	T		G	G	G		T	T