PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c5j44B_

Fold library id	PDB Header	Molecule	Title
c5j44B_	2.91	PDB header: hydrolase	Chain: B: PDB Molecule: serine protease sepa autotransporter;

Links to external resources
Added to library: Sat Apr 15 09:09:09 2017

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence A T V S A E I P Y Q I F R D F A E N K G Q F T P G T T N I S I Y D K Q G N L V G K L D K A P M A D F S S A T I T T G S L P P G D H T L Y S P

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T S
T
T T
T T
S
S S S
S S
T T B
S B B T T B
T T S
T

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence Q Y V V T A K H V S G S D T M S F G Y A K N T Y T A V G T N N N S G L D I K T R R L S K L V T E V A P A E V S D I G A V S G A Y Q A G G R F

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T
T T
S
S S S S T T S
S S S S
S S
S S
B
S S
S
T T T T S T T S S

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence T E F Y R L G G G M Q Y V K D K N G N R T Q V Y T N G G F L V G G T V S A L N S Y N N G Q M I T A Q T G D I F N P A N G P L A N Y L N M G D

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S
T T
T T
T T T T
S
T T
G G G
T T B
B
T T

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240 . . . . . . . . . 250 . . . . . . . . . 260 . . . . . . . . . 270 . . . . . . . . . 280

Sequence S G S P L F A Y D S L Q K K W V L I G V L S S G T N Y G N N W V V T T Q D F L G Q Q P Q N D F D K T I A Y T S G E G V L Q W K Y D A A N G T

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T
T T T T
S S
T T B
S
S S S
T T T T

. . . . . . . . . 290 . . . . . . . . . 300 . . . . . . . . . 310 . . . . . . . . . 320 . . . . . . . . . 330 . . . . . . . . . 340 . . . . . . . . . 350

Sequence G T L T Q G N T T W D M H G K K G N D L N A G K N L L F T G N N G E V V L Q N S V N Q G A G Y L Q F A G D Y R V S A L N G Q T W M G G G I I

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T
B T T B G G G
B S S S S S
T T
S S
S S S
B S S

. . . . . . . . . 360 . . . . . . . . . 370 . . . . . . . . . 380 . . . . . . . . . 390 . . . . . . . . . 400 . . . . . . . . . 410 . . . . . . . . . 420

Sequence T D K G T H V L W Q V N G V A G D N L H K T G E G T L T V N G T G V N A G G L K V G D G T V I L N Q Q A D A D G K V Q A F S S V G I A S G R

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T
B
T T
S S S
B S B
S
S S
B
S S S
B S
S
S S

. . . . . . . . . 430 . . . . . . . . . 440 . . . . . . . . . 450 . . . . . . . . . 460 . . . . . . . . . 470 . . . . . . . . . 480 . . . . . . . . . 490

Sequence P T V V L S D S Q Q V N P D N I S W G Y R G G R L E L N G N N L T F T R L Q A A D Y G A I I T N N S E K K S T V T L D L Q T L K A S D I N V

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S T T S S
G G G
T T
T T
S
S T T
S S S
S S
G G G

. . . . . . . . . 500 . . . . . . . . . 510 . . . . . . . . . 520 . . . . . . . . . 530 . . . . . . . . . 540 . . . . . . . . . 550 . . . . . . . . . 560

Sequence P V N T V S I F G G R G A P G D L Y Y D S S T K Q Y F I L K A S S Y S P F F S D L N N S S V W Q N V G K D R N K A I D T V K Q Q K I E A S S

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S
T T
T T T T
S S
S T T G G G S
S S S
S

. . . . . . . . . 570 . . . . . . . . . 580 . . . . . . . . . 590 . . . . . . . . . 600 . . . . . . . . . 610 . . . . . . . . . 620 . . . . . . . . . 630

Sequence Q P Y M Y H G Q L N G N M D V N I P Q L S G K D V L A L D G S V N L P E G S I T K K S G T L I F Q G H P V I H A G T T T S S S Q S D W E T R

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S S
S T T
S
S S
S S
T T
T T
S

. . . . . . . . . 640 . . . . . . . . . 650 . . . . . . . . . 660 . . . . . . . . . 670 . . . . . . . . . 680 . . . . . . . . . 690 . . . . . . . . . 700

Sequence Q F T L E K L K L D A A T F H L S R N G K M Q G D I N A T N G S T V I L G S S R V F T D R S D G T G N A V S S V E G S A T A T T V G D Q S D

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S
T T S S
T
T T T T T T S
S S S S S

. . . . . . . . . 710 . . . . . . . . . 720 . . . . . . . . . 730 . . . . . . . . . 740 . . . . . . . . . 750 . . . . . . . . . 760 . . . . . . . . . 770

Sequence Y S G N V T L E N K S S L Q I M E R F T G G I E A Y D S T V S V T S Q N A V F D R V G S F V N S S L T L G K G A K L T A Q S G I F S T G A V

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S S
S S
S S T
T T
S S
S S

. . . . . . . . . 780 . . . . . . . . . 790 . . . . . . . . . 800 . . . . . . . . . 810 . . . . . . . . . 820 . . . . . . . . . 830 . . . . . . . . . 840

Sequence D V K E N A S L T L T G M P S A Q K Q G Y Y S P V I S T T E G I N L E D N A S F S V K N M G Y L S S D I H A G T T A A T I N L G D S D A D A

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T
S S S T T
S
T T
S S
T T S
S
S S S

. . . . . . . . . 850 . . . . . . . . . 860 . . . . . . . . . 870 . . . . . . . . . 880 . . . . . . . . . 890 . . . . . . . . . 900 . . . . . . . . . 910

Sequence G K T D S P L F S S L M K G Y N A V L R G S I T G A Q S T V N M I N A L W Y S D G K S E A G A L K A K G S R I E L G D G K H F A T L Q V K E

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S T T S T T
S
S
S
S
S
S S S

. . . . . . . . . 920 . . . . . . . . . 930 . . . . . . . . . 940 . . . . . . . . . 950 . . . . . . . . . 960 . . . . . . . . . 970 . . . . . . . . . 980

Sequence L S A D N T T F L M H T N N S R A D Q L N V T D K L S G S N N S V L V D F L N K P A S E M S V T L I T A P K G S D E K T F T A G T Q Q I G F

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S
S S
B
S
S S
S S
T T
T T S
T T

. . . . . . . . . 990 . . . . . . . . . 1000 . . . . . .

Sequence S N V T P V I S T E K T D D A T K W V L T G Y Q T T

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	A	T	V	S	A	E	I	P	Y	Q	I	F	R	D	F	A	E	N	K	G	Q	F	T	P	G	T	T	N	I	S	I	Y	D	K	Q	G	N	L	V	G	K	L	D	K	A	P	M	A	D	F	S	S	A	T	I	T	T	G	S	L	P	P	G	D	H	T	L	Y	S	P
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)					T	T	S											T		T	T			T	T			S						S	S	S								S	S						T	T	B		S	B	B	T	T	B		T	T	S						T
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	Q	Y	V	V	T	A	K	H	V	S	G	S	D	T	M	S	F	G	Y	A	K	N	T	Y	T	A	V	G	T	N	N	N	S	G	L	D	I	K	T	R	R	L	S	K	L	V	T	E	V	A	P	A	E	V	S	D	I	G	A	V	S	G	A	Y	Q	A	G	G	R	F
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T						T	T			S		S				S	S	S	T	T	S											S	S	S	S							S	S				S	S					B		S	S		S		T	T	T	T	S	T	T	S	S
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	T	E	F	Y	R	L	G	G	G	M	Q	Y	V	K	D	K	N	G	N	R	T	Q	V	Y	T	N	G	G	F	L	V	G	G	T	V	S	A	L	N	S	Y	N	N	G	Q	M	I	T	A	Q	T	G	D	I	F	N	P	A	N	G	P	L	A	N	Y	L	N	M	G	D
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)									S							T	T									T	T															T	T	T	T							S		T	T		G	G	G		T	T	B		B			T	T
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280
Sequence	S	G	S	P	L	F	A	Y	D	S	L	Q	K	K	W	V	L	I	G	V	L	S	S	G	T	N	Y	G	N	N	W	V	V	T	T	Q	D	F	L	G	Q	Q	P	Q	N	D	F	D	K	T	I	A	Y	T	S	G	E	G	V	L	Q	W	K	Y	D	A	A	N	G	T
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T	T								T	T	T	T													S	S													T						T	B		S						S	S	S									T	T	T	T
	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350
Sequence	G	T	L	T	Q	G	N	T	T	W	D	M	H	G	K	K	G	N	D	L	N	A	G	K	N	L	L	F	T	G	N	N	G	E	V	V	L	Q	N	S	V	N	Q	G	A	G	Y	L	Q	F	A	G	D	Y	R	V	S	A	L	N	G	Q	T	W	M	G	G	G	I	I
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)						T	T									B	T	T	B	G	G	G			B					S	S	S						S	S					T	T						S	S							S	S	S		B			S	S
	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence	T	D	K	G	T	H	V	L	W	Q	V	N	G	V	A	G	D	N	L	H	K	T	G	E	G	T	L	T	V	N	G	T	G	V	N	A	G	G	L	K	V	G	D	G	T	V	I	L	N	Q	Q	A	D	A	D	G	K	V	Q	A	F	S	S	V	G	I	A	S	G	R
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			T	T								B			T	T							S	S	S							B	S	B			S						S	S							B			S	S	S			B	S		S						S	S
	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490
Sequence	P	T	V	V	L	S	D	S	Q	Q	V	N	P	D	N	I	S	W	G	Y	R	G	G	R	L	E	L	N	G	N	N	L	T	F	T	R	L	Q	A	A	D	Y	G	A	I	I	T	N	N	S	E	K	K	S	T	V	T	L	D	L	Q	T	L	K	A	S	D	I	N	V
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)						S	S	T	T	S	S		G	G	G					T	T							T	T						S						S	T	T							S	S	S										S	S		G	G	G
	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560
Sequence	P	V	N	T	V	S	I	F	G	G	R	G	A	P	G	D	L	Y	Y	D	S	S	T	K	Q	Y	F	I	L	K	A	S	S	Y	S	P	F	F	S	D	L	N	N	S	S	V	W	Q	N	V	G	K	D	R	N	K	A	I	D	T	V	K	Q	Q	K	I	E	A	S	S
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)							S	S						T	T						T	T	T	T							S	S				S	T	T	G	G	G	S		S	S	S						S
	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630
Sequence	Q	P	Y	M	Y	H	G	Q	L	N	G	N	M	D	V	N	I	P	Q	L	S	G	K	D	V	L	A	L	D	G	S	V	N	L	P	E	G	S	I	T	K	K	S	G	T	L	I	F	Q	G	H	P	V	I	H	A	G	T	T	T	S	S	S	Q	S	D	W	E	T	R
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)							S				S	S									S	T	T							S					S	S							S	S												T	T					T	T		S
	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.	.	660	.	.	.	.	.	.	.	.	.	670	.	.	.	.	.	.	.	.	.	680	.	.	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700
Sequence	Q	F	T	L	E	K	L	K	L	D	A	A	T	F	H	L	S	R	N	G	K	M	Q	G	D	I	N	A	T	N	G	S	T	V	I	L	G	S	S	R	V	F	T	D	R	S	D	G	T	G	N	A	V	S	S	V	E	G	S	A	T	A	T	T	V	G	D	Q	S	D
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)											S							T	T											S	S						T								T	T	T	T	T	T	S													S	S	S	S	S
	.	.	.	.	.	.	.	.	.	710	.	.	.	.	.	.	.	.	.	720	.	.	.	.	.	.	.	.	.	730	.	.	.	.	.	.	.	.	.	740	.	.	.	.	.	.	.	.	.	750	.	.	.	.	.	.	.	.	.	760	.	.	.	.	.	.	.	.	.	770
Sequence	Y	S	G	N	V	T	L	E	N	K	S	S	L	Q	I	M	E	R	F	T	G	G	I	E	A	Y	D	S	T	V	S	V	T	S	Q	N	A	V	F	D	R	V	G	S	F	V	N	S	S	L	T	L	G	K	G	A	K	L	T	A	Q	S	G	I	F	S	T	G	A	V
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)									S	S							S										S								S	S											T							T	T						S	S					S	S
	.	.	.	.	.	.	.	.	.	780	.	.	.	.	.	.	.	.	.	790	.	.	.	.	.	.	.	.	.	800	.	.	.	.	.	.	.	.	.	810	.	.	.	.	.	.	.	.	.	820	.	.	.	.	.	.	.	.	.	830	.	.	.	.	.	.	.	.	.	840
Sequence	D	V	K	E	N	A	S	L	T	L	T	G	M	P	S	A	Q	K	Q	G	Y	Y	S	P	V	I	S	T	T	E	G	I	N	L	E	D	N	A	S	F	S	V	K	N	M	G	Y	L	S	S	D	I	H	A	G	T	T	A	A	T	I	N	L	G	D	S	D	A	D	A
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)				T	T											S	S	S	T	T										S						T	T							S	S										T	T	S							S			S	S	S
	.	.	.	.	.	.	.	.	.	850	.	.	.	.	.	.	.	.	.	860	.	.	.	.	.	.	.	.	.	870	.	.	.	.	.	.	.	.	.	880	.	.	.	.	.	.	.	.	.	890	.	.	.	.	.	.	.	.	.	900	.	.	.	.	.	.	.	.	.	910
Sequence	G	K	T	D	S	P	L	F	S	S	L	M	K	G	Y	N	A	V	L	R	G	S	I	T	G	A	Q	S	T	V	N	M	I	N	A	L	W	Y	S	D	G	K	S	E	A	G	A	L	K	A	K	G	S	R	I	E	L	G	D	G	K	H	F	A	T	L	Q	V	K	E
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)					S	T					T	S	T	T		S					S													S							S											S								S	S	S
	.	.	.	.	.	.	.	.	.	920	.	.	.	.	.	.	.	.	.	930	.	.	.	.	.	.	.	.	.	940	.	.	.	.	.	.	.	.	.	950	.	.	.	.	.	.	.	.	.	960	.	.	.	.	.	.	.	.	.	970	.	.	.	.	.	.	.	.	.	980
Sequence	L	S	A	D	N	T	T	F	L	M	H	T	N	N	S	R	A	D	Q	L	N	V	T	D	K	L	S	G	S	N	N	S	V	L	V	D	F	L	N	K	P	A	S	E	M	S	V	T	L	I	T	A	P	K	G	S	D	E	K	T	F	T	A	G	T	Q	Q	I	G	F
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)					S									S	S		B												S									S	S				S	S										T	T			T	T	S									T	T
	.	.	.	.	.	.	.	.	.	990	.	.	.	.	.	.	.	.	.	1000	.	.	.	.	.	.
Sequence	S	N	V	T	P	V	I	S	T	E	K	T	D	D	A	T	K	W	V	L	T	G	Y	Q	T	T
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)													S	S