PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: d1tffa_

Fold library id	Fold	Superfamily	Family
d1tffa_	Cysteine proteinases	Cysteine proteinases	Ubiquitin thiolesterase protein OTUB2 (Otubain-2)

Links to external resources
Added to library: Tue Mar 16 12:26:32 2010

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence N L I S E K C D I L S I L R D H P E N R I Y R R K I E E L S K R F T A I R K T K G D R N C F Y R A L G Y S Y L E S L L G K S R E I F K F K E

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
B
B
T T S
S G G G G G
B
S S
T T

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence R V L Q T P N D L L A A G F E E H K F R N F F N A F Y S V V E L V E K D G S V S S L L K V F N D Q S A S D H I V Q F L R L L T S A F I R N R

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T
T
T S T

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence A D F F R H F I D E E X D I K D F C T H E V E P X A T E C D H I Q I T A L S Q A L S I A L Q V E Y V D H H V F P E A A T P S V Y L L Y K T S

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) G G G S
T T S
T S S T T
T
S S
S T T

. . . . . . . . . 220 .

Sequence H Y N I L Y A A D K H

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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Phyre2 is part of Genome3D

	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	N	L	I	S	E	K	C	D	I	L	S	I	L	R	D	H	P	E	N	R	I	Y	R	R	K	I	E	E	L	S	K	R	F	T	A	I	R	K	T	K	G	D	R	N	C	F	Y	R	A	L	G	Y	S	Y	L	E	S	L	L	G	K	S	R	E	I	F	K	F	K	E
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			B				B		T	T					S		S	G	G	G	G	G																	B			S	S																T	T
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	R	V	L	Q	T	P	N	D	L	L	A	A	G	F	E	E	H	K	F	R	N	F	F	N	A	F	Y	S	V	V	E	L	V	E	K	D	G	S	V	S	S	L	L	K	V	F	N	D	Q	S	A	S	D	H	I	V	Q	F	L	R	L	L	T	S	A	F	I	R	N	R
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)												T	T																							T											T	S																						T
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	A	D	F	F	R	H	F	I	D	E	E	X	D	I	K	D	F	C	T	H	E	V	E	P	X	A	T	E	C	D	H	I	Q	I	T	A	L	S	Q	A	L	S	I	A	L	Q	V	E	Y	V	D	H	H	V	F	P	E	A	A	T	P	S	V	Y	L	L	Y	K	T	S
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)					G	G	G	S		T	T	S										T	S	S	T	T																T																	S	S		S							T	T
	.	.	.	.	.	.	.	.	.	220	.
Sequence	H	Y	N	I	L	Y	A	A	D	K	H
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)