PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: d1dowa_

Fold library id	Fold	Superfamily	Family
d1dowa_	Four-helical up-and-down bundle	alpha-catenin/vinculin-like	alpha-catenin/vinculin

Links to external resources
Added to library: Tue Mar 16 13:53:33 2010

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence K A H V L A A S V E Q A T E N F L E K G D K I A K E S Q F L K E E L V V A V E D V R K Q G D L X K S A A G E F A D D P C S S V K R G N X V R

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T
S S S S T T

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence A A R A L L S A V T R L L I L A D X A D V Y K L L V Q L K V V E D G I L K L R N A G N E Q D L G I Q Y K A L K P E V D K L N I X A A K R Q Q

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T
S S T

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . .

Sequence E L K D V G N R D Q X A A A R G I L Q K N V P I L Y T A S Q A C L Q H P D V A A Y K A N R D L I Y K Q L Q Q A V T G I S N A A Q A

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T
T T
T

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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All images and data generated by Phyre2 are free to use in any publication with acknowledgement
Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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Phyre2 is part of Genome3D

	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	K	A	H	V	L	A	A	S	V	E	Q	A	T	E	N	F	L	E	K	G	D	K	I	A	K	E	S	Q	F	L	K	E	E	L	V	V	A	V	E	D	V	R	K	Q	G	D	L	X	K	S	A	A	G	E	F	A	D	D	P	C	S	S	V	K	R	G	N	X	V	R
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)		T																										S	S	S																												S	T	T
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	A	A	R	A	L	L	S	A	V	T	R	L	L	I	L	A	D	X	A	D	V	Y	K	L	L	V	Q	L	K	V	V	E	D	G	I	L	K	L	R	N	A	G	N	E	Q	D	L	G	I	Q	Y	K	A	L	K	P	E	V	D	K	L	N	I	X	A	A	K	R	Q	Q
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																																								T		S	S																											T
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.
Sequence	E	L	K	D	V	G	N	R	D	Q	X	A	A	A	R	G	I	L	Q	K	N	V	P	I	L	Y	T	A	S	Q	A	C	L	Q	H	P	D	V	A	A	Y	K	A	N	R	D	L	I	Y	K	Q	L	Q	Q	A	V	T	G	I	S	N	A	A	Q	A
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T																																			T	T																											T