PHYRE Protein Fold Recognition Server

Subscribe to Phyre at Google Groups

Email:

Visit Phyre at Google Groups

Protein Homology/analogY Recognition Engine V 2.0

Fold library entry viewer: c8e20A_

Fold library id	PDB Header	Molecule	Title
c8e20A_	3.60	PDB header: signaling protein	Chain: A: PDB Molecule: isoform i of neurofibromin;

Links to external resources
Added to library: Sat Apr 29 08:42:04 2023

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence A H R P V E W V Q A V V S R F D E Q L P I K T G T H T K V S T E H N K E C L I N I S K Y K F S L V I S G L T T I L K N V N N M R I F G E A A

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T S
T T T T T S
S S

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence E K N L Y L S Q L I I L D T L E K C L A G Q P K D T M R L D E T M L V K Q L L P E I C H F L H T C R Q H A A E L R N S A S G V L F S L S C N

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S
G G G
T T T T T T T T T T T

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence N F N A V F S R I S T R L Q E L T V C D N V D V H D I E L L Q Y I N V D C A K L K R L L K E T A F K F K A L K K V A Q L A V I N S L E K A F

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T T S G G G T S
T T S

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240 . . . . . . . . . 250 . . . . . . . . . 260 . . . . . . . . . 270 . . . . . . . . . 280

Sequence W N W V E N Y P D E F T K L Y Q I P Q T D M A E C A E K L F D L V D G F A E S T K R K A A V W P L Q I I L L I L C P E I I Q D I S K D E N N

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T S
S T
G G G

. . . . . . . . . 290 . . . . . . . . . 300 . . . . . . . . . 310 . . . . . . . . . 320 . . . . . . . . . 330 . . . . . . . . . 340 . . . . . . . . . 350

Sequence M N K K L F L D S L R K A L A G H S R Q L T E S A A I A C V K L C K A S T Y I N W E D N S V I F L L V Q S M V V D L K N L L F N P S K P F S

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T
S
S S
T T T
S S S

. . . . . . . . . 360 . . . . . . . . . 370 . . . . . . . . . 380 . . . . . . . . . 390 . . . . . . . . . 400 . . . . . . . . . 410 . . . . . . . . . 420

Sequence A D V D L M I D C L V S C F R I S P H N N Q H F K I C L A Q N S P S T F H Y V L V N S L H R I I T N S A L D W W P K I D A V Y C H S V E L R

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S
S
S S S
S S
S S S S
S
S
G G G

. . . . . . . . . 430 . . . . . . . . . 440 . . . . . . . . . 450 . . . . . . . . . 460 . . . . . . . . . 470 . . . . . . . . . 480 . . . . . . . . . 490

Sequence N M F G E T L H K A V Q T D L E T R S Y K Y L L L S M V K L I H A D P K L L L C N P R K Q G P E T Q G S T A E L I T G L V Q L V P Q S H M P

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T T T T
S
T T
S S G G G G G T T T S S
S

. . . . . . . . . 500 . . . . . . . . . 510 . . . . . . . . . 520 . . . . . . . . . 530 . . . . . . . . . 540 . . . . . . . . . 550 . . . . . . . . . 560

Sequence E I A Q E A M E A L L V L H Q L D S I D L W N P D A P V E T F W E I S S Q M L F Y I C K K L T S H Q M L S S T E I L K W L R E I L I C R N K

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T S T T T
S S
T
T T

. . . . . . . . . 570 . . . . . . . . . 580 . . . . . . . . . 590 . . . . . . . . . 600 . . . . . . . . . 610 . . . . . . . . . 620 . . . . . . . . . 630

Sequence F L L K N K Q A D R S L L F Y G V G T P P I C R Q A Q T K L E V A L Y M F L W N P D T E A V L V A M S C F R H L C E E A D I R C V S V H N L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T T
T T
S S S T
G G G T

. . . . . . . . . 640 . . . . . . . . . 650 . . . . . . . . . 660 . . . . . . . . . 670 . . . . . . . . . 680 . . . . . . . . . 690 . . . . . . . . . 700

Sequence L P N Y N T F M E F A S V S N M M S T G R A A L Q K R V M A L L R R I E H P T A G N T E A W E D T H A K W E Q A T K L I L N Y P L S D T D S

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T S
S S T
S
T T

. . . . . . . . . 710 . . . . . . . . . 720 . . . . . . . . . 730 . . . . . . . . . 740 . . . . . . . . . 750 . . . . . . . . . 760 . . . . . . . . . 770

Sequence L Q E W I N M T G F L C A L G G V C L Q Q R S N S T P V S K F M D R L L S L M V C N H E K V G L Q I R T N V K D L V G L E L S P A L Y P M L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T
T T
T T T S
G G G

. . . . . . . . . 780 . . . . . . . . . 790 . . . . . . . . . 800 . . . . . . . . . 810 . . . . . . . . . 820 . . . . . . . . . 830 . . . . . . . . . 840

Sequence F N K L K N T I S K F F D S Q G Q V L L T D T N T Q F V E Q T I A I M K N L L D N H T E G S S E H L G Q A S I E T M M L N L V R Y V R V L G

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T S B
T T S
B
S
T T T S S
T T

. . . . . . . . . 850 . . . . . . . . . 860 . . . . . . . . . 870 . . . . . . . . . 880 . . . . . . . . . 890 . . . . . . . . . 900 . . . . . . . . . 910

Sequence N M V H A I Q I K T K L C Q L V E V M M A R R D D L S F C Q E M K F R N K M V E Y L T D W V M G T S N Q A A D D D V K C L T R D L D Q A S M

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S S T T T T S
S
T T T S S S S T T T
S

. . . . . . . . . 920 . . . . . . . . . 930 . . . . . . . . . 940 . . . . . . . . . 950 . . . . . . . . . 960 . . . . . . . . . 970 . . . . . . . . . 980

Sequence E A V V S L L A G L P L Q P E E G D G V E L M E A K S Q L F L K Y F T L F M N L L N D C S E M S R R L A S L R H C T V L A M S N L L N A N V

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T
S
S S
T S
T T
G

. . . . . . . . . 990 . . . . . . . . . 1000 . . . . . . . . . 1010 . . . . . . . . . 1020 . . . . . . . . . 1030 . . . . . . . . . 1040 . . . . . . . . . 1050

Sequence D S G L M H S I G L G Y H K D L Q T R A T F M E V L T K I L Q Q G T E F D T L V E L V T M M G D Q G E L P I A M A L A N V V P C S Q W D E L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) G G T G G G G S
S S S S T T T T G G G T T
S T
T T
S
G G G

. . . . . . . . . 1060 . . . . . . . . . 1070 . . . . . . . . . 1080 . . . . . . . . . 1090 . . . . . . . . . 1100 . . . . . . . . . 1110 . . . . . . . . . 1120

Sequence A R V L V T L F D S R H L L Y Q L L W N M F S K E V E L A D S M Q T L F R G N S L A S K I M T F C F K V Y G A T Y L Q K L L D P L S L E E N

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T T T
T T
S G G G S T T
S S S T T T T T T T T T S S
T T G G

. . . . . . . . . 1130 . . . . . . . . . 1140 . . . . . . . . . 1150 . . . . . . . . . 1160 . . . . . . . . . 1170 . . . . . . . . . 1180 . . . . . . . . . 1190

Sequence Q R N L L Q M T E K F F H A I I S S S S E F P P Q L R S V C H C L Y Q V V S Q R F P Q N S I G A V G S A M F L R F I N P A I V S P Y E A P R

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) G T T T T T T
S
S S T T T T T T
S S

. . . . . . . . . 1200 . . . . . . . . . 1210 . . . . . . . . . 1220 . . . . . . . . . 1230 . . . . . . . . . 1240 . . . . . . . . . 1250 . . . . . . . . . 1260

Sequence I E R G L K L M S K I L Q S I A N H H M R P F N D F V K S N F D A A R R F F L D I A S H R L L W N N Q E K I G Q Y L S S R P F D K M A T L L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S G G G G T G G G G T T
T T
S S T T

. . . . . . . . . 1270 . . . . . . . . . 1280 . . . . . . . . . 1290 . . . . . . . . . 1300 . . . . . . . . . 1310 . . . . . . . . . 1320 . . . . . . . . . 1330

Sequence A Y L G P P E K E E F K A L K T L S I F Y Q A G T S K A G N P I F Y Y V A R R F K T G Q I N G D L L I Y H V L L T L K P Y Y A K P Y E I V V

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T
S S T T T T
B T T S
G G G
T T T S
T T T T T T T S

. . . . . . . . . 1340 . . . . . . . . . 1350 . . . . . . . . . 1360 . . . . . . . . . 1370 . . . . . . . . . 1380 . . . . . . . . . 1390 . . . . . . . . . 1400

Sequence D L T H T G P S N R F K T D F L S K W F V V F P G F A Y D N V S A V Y I Y N C N S W V R E Y T K Y H E R L L T G L K G S K R L V F I D C P G

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T
G G G
S
S
T T T T S T T T T T
T T S S

. . . . . . . . . 1410 . . . . . . . . . 1420 . . . . . . . . . 1430 . . . . . . . . . 1440 . . . . . . . . . 1450 . . . . . . . . . 1460 . . . . . . . . . 1470

Sequence K L A E H I E H E Q Q K L P A A T L A L E E D L K V F H N A L K L A H K D T K V S I K V G S T A V Q V T S A E R T K V L G Q S V F L N D I Y

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T B G G G
T T S T T
T T S S S
S S
S
T T

. . . . . . . . . 1480 . . . . . . . . . 1490 . . . . . . . . . 1500 . . . . . . . . . 1510 . . . . . . . . . 1520 . . . . . . . . . 1530 . . . . . . . . . 1540

Sequence Y A S E I E E I C L V D E N Q F T L T I A N Q G T P L T F M H Q E C E A I V Q S I I H I R T R W E L S Q P D I R P K D V P G T L L N I A L L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) G G G
S S
T T
S
T T T
S S S

. . . . . . . . . 1550 . . . . . . . . . 1560 . . . . . . . . . 1570 . . . . . . . . . 1580 . . . . . . . . . 1590 . . . . . . . . . 1600 . . . . . . . . . 1610

Sequence N L G S S D P S L R S A A Y N L L C A L T C T F N L K I E G Q L L E T S G L C I P A N N T L F I V S I S K T L A A N E P H L T L E F L E E C

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T
S
T
S T T
S S
S
S
S S

. . . . . . . . . 1620 . . . . . . . . . 1630 . . . . . . . . . 1640 . . . . . . . . . 1650 . . . . . . . . . 1660 . . . . . . . . . 1670 . . . . . . . . . 1680

Sequence I S G F S K S S I E L K H L C L E Y M T P W L S N L V R F C K H N D D A K R Q R V T A I L D K L I T M T I N E K Q M Y P S I Q A K I W G S L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S
G G G G S
T T

. . . . . . . . . 1690 . . . . . . . . . 1700 . . . . . . . . . 1710 . . . . . . . . . 1720 . . . . . . . . . 1730 . . . . . . . . . 1740 . . . . . . . . . 1750

Sequence G Q I T D L L D V V L D S F I K T S A T G G L G S I K A E V M A D T A V A L A S G N V K L V S S K V I G R M C K I I D K T C L S P T P T L E

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T
G G G
T T S
G G G S
S S S T

. . . . . . . . . 1760 . . . . . . . . . 1770 . . . . . . . . . 1780 . . . . . . . . . 1790 . . . . . . . . . 1800 . . . . . . . . . 1810 . . . . . . . . . 1820

Sequence Q H L M W D D I A I L A R Y M L M L S F N N S L D V A A H L P Y L F H V V T F L V A T G P L S L R A S T H G L V I N I I H S L C T C S Q L H

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T S T T G G G T T
T T
S S T T
T T S

. . . . . . . . . 1830 . . . . . . . . . 1840 . . . . . . . . . 1850 . . . . . . . . . 1860 . . . . . . . . . 1870 . . . . . . . . . 1880 . . . . . . . . . 1890

Sequence F S E E T K Q V L R L S L T E F S L P K F Y L L F G I S K V K S A A V I A F R S E T F A L T S L E T V T E A L L E I M E A C M R D I P T C K

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T S T T
S
S
S
T T
T T

. . . . . . . . . 1900 . . . . . . . . . 1910 . . . . . . . . . 1920 . . . . . . . . . 1930 . . . . . . . . . 1940 . . . . . . . . . 1950 . . . . . . . . . 1960

Sequence W L D Q W T E L A Q R F A F Q Y N P S L Q P R A L V V F G C I S K R V S H G Q I K Q I I R I L S K A L E S C L K G P D T Y N S Q V L I E A T

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S S
S S
S
S

. . . . . . . . . 1970 . . . . . . . . . 1980 . . . . . . . . . 1990 . . . . . . . . . 2000 . . . . . . . . . 2010 . . . . . . . . . 2020 . . . . . . . . . 2030

Sequence V I A L T K L Q P L L N K D S P L H K A L F W V A V A V L Q L D E V N L Y S A G T A L L E Q N L H T L D S L R I F N D K S P E E V F M A I R

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) G G G S
T T
T T
T T
S S S S

. . . . . . . . . 2040 . . . . . . . . . 2050 . . . . . . . . . 2060 . . . . . . . . . 2070 . . . . . . . . . 2080 . . . . . . . . . 2090 . . . . . . . . . 2100

Sequence N P L E W H C K Q M D H F V G L N F N S N F N F A L V G H L L K G Y R H P S P A I V A R T V R I L H T L L T L V N K H R N C D K F E V N T Q

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) G G G T
T T T
T
S S T T
T T
T T

. . . . . . . . . 2110 . . . . . . . . . 2120 . . . . . . . . . 2130 . . . . . . . . . 2140 . . . . . . . . . 2150 . . . . . . . . . 2160 . . . . . . . . . 2170

Sequence S V A Y L A A L L T V S E E V R S R C V L L D E E V L T D P K I Q A L L L T V L A T L V K Y T T D E F D Q R I L Y E Y L A E A S V V F P K V

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T
S
T T T T T S S
T T T

. . . . . . . . . 2180 . . . . . . . . . 2190 . . . . . . . . . 2200 . . . . . . . . . 2210 . . . . . . . . . 2220 . . . . . . . . . 2230 . . . . . . . . . 2240

Sequence F P V V H N L L D S K I N T L L S L C Q D P N L L N P I H G I V Q S V V Y H E E S P P Q Y Q T S Y L Q S F G F N G L W R F A G P F S K Q T Q

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T T T
G G G T T T T
G G G G T T T S
S S S S

. . . . . . . . . 2250 . . . . . . . . . 2260

Sequence I P D Y A E L I V K F L D A L I D T Y L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T T T

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Close JSmol

Interactive 3D view in JSmol

Phyre is now FREE for commercial users!

All images and data generated by Phyre2 are free to use in any publication with acknowledgement
Accessibility Statement

Please cite: The Phyre2 web portal for protein modeling, prediction and analysis

Kelley LA et al. Nature Protocols 10, 845-858 (2015) [paper] [Citation link]

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

Disclaimer

Terms and Conditions

Structural Biology Group logo Imperial logo

BBSRC logo
Phyre2 is part of Genome3D

	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	A	H	R	P	V	E	W	V	Q	A	V	V	S	R	F	D	E	Q	L	P	I	K	T	G	T	H	T	K	V	S	T	E	H	N	K	E	C	L	I	N	I	S	K	Y	K	F	S	L	V	I	S	G	L	T	T	I	L	K	N	V	N	N	M	R	I	F	G	E	A	A
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)		T																S																								T	T	T	T	T																S					S	S
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	E	K	N	L	Y	L	S	Q	L	I	I	L	D	T	L	E	K	C	L	A	G	Q	P	K	D	T	M	R	L	D	E	T	M	L	V	K	Q	L	L	P	E	I	C	H	F	L	H	T	C	R	Q	H	A	A	E	L	R	N	S	A	S	G	V	L	F	S	L	S	C	N
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																						S		G	G	G		T	T	T	T											T	T	T	T	T	T	T
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	N	F	N	A	V	F	S	R	I	S	T	R	L	Q	E	L	T	V	C	D	N	V	D	V	H	D	I	E	L	L	Q	Y	I	N	V	D	C	A	K	L	K	R	L	L	K	E	T	A	F	K	F	K	A	L	K	K	V	A	Q	L	A	V	I	N	S	L	E	K	A	F
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																									T	T	T	S	G	G	G	T	S																			T	T	S
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280
Sequence	W	N	W	V	E	N	Y	P	D	E	F	T	K	L	Y	Q	I	P	Q	T	D	M	A	E	C	A	E	K	L	F	D	L	V	D	G	F	A	E	S	T	K	R	K	A	A	V	W	P	L	Q	I	I	L	L	I	L	C	P	E	I	I	Q	D	I	S	K	D	E	N	N
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)								T	T								S																						S																	T												G	G	G
	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350
Sequence	M	N	K	K	L	F	L	D	S	L	R	K	A	L	A	G	H	S	R	Q	L	T	E	S	A	A	I	A	C	V	K	L	C	K	A	S	T	Y	I	N	W	E	D	N	S	V	I	F	L	L	V	Q	S	M	V	V	D	L	K	N	L	L	F	N	P	S	K	P	F	S
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)															T	T																							S		S	S			T	T																	T		S	S	S
	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence	A	D	V	D	L	M	I	D	C	L	V	S	C	F	R	I	S	P	H	N	N	Q	H	F	K	I	C	L	A	Q	N	S	P	S	T	F	H	Y	V	L	V	N	S	L	H	R	I	I	T	N	S	A	L	D	W	W	P	K	I	D	A	V	Y	C	H	S	V	E	L	R
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																		S	S									S		S	S	S																	S	S			S	S	S	S			S		S		G	G	G
	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490
Sequence	N	M	F	G	E	T	L	H	K	A	V	Q	T	D	L	E	T	R	S	Y	K	Y	L	L	L	S	M	V	K	L	I	H	A	D	P	K	L	L	L	C	N	P	R	K	Q	G	P	E	T	Q	G	S	T	A	E	L	I	T	G	L	V	Q	L	V	P	Q	S	H	M	P
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)							T	T	T	T	T																								S							T	T		S	S	G	G	G	G	G	T										T	T	S	S			S
	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560
Sequence	E	I	A	Q	E	A	M	E	A	L	L	V	L	H	Q	L	D	S	I	D	L	W	N	P	D	A	P	V	E	T	F	W	E	I	S	S	Q	M	L	F	Y	I	C	K	K	L	T	S	H	Q	M	L	S	S	T	E	I	L	K	W	L	R	E	I	L	I	C	R	N	K
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)														T	S					T	T	T		S	S																								T			T	T
	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630
Sequence	F	L	L	K	N	K	Q	A	D	R	S	L	L	F	Y	G	V	G	T	P	P	I	C	R	Q	A	Q	T	K	L	E	V	A	L	Y	M	F	L	W	N	P	D	T	E	A	V	L	V	A	M	S	C	F	R	H	L	C	E	E	A	D	I	R	C	V	S	V	H	N	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)														T	T	T																						T	T		S	S	S	T																							G	G	G	T
	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.	.	660	.	.	.	.	.	.	.	.	.	670	.	.	.	.	.	.	.	.	.	680	.	.	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700
Sequence	L	P	N	Y	N	T	F	M	E	F	A	S	V	S	N	M	M	S	T	G	R	A	A	L	Q	K	R	V	M	A	L	L	R	R	I	E	H	P	T	A	G	N	T	E	A	W	E	D	T	H	A	K	W	E	Q	A	T	K	L	I	L	N	Y	P	L	S	D	T	D	S
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)		T	T													S			S	S														T			S																													T	T
	.	.	.	.	.	.	.	.	.	710	.	.	.	.	.	.	.	.	.	720	.	.	.	.	.	.	.	.	.	730	.	.	.	.	.	.	.	.	.	740	.	.	.	.	.	.	.	.	.	750	.	.	.	.	.	.	.	.	.	760	.	.	.	.	.	.	.	.	.	770
Sequence	L	Q	E	W	I	N	M	T	G	F	L	C	A	L	G	G	V	C	L	Q	Q	R	S	N	S	T	P	V	S	K	F	M	D	R	L	L	S	L	M	V	C	N	H	E	K	V	G	L	Q	I	R	T	N	V	K	D	L	V	G	L	E	L	S	P	A	L	Y	P	M	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																						T	T																T	T				T	T	T																S		G	G	G
	.	.	.	.	.	.	.	.	.	780	.	.	.	.	.	.	.	.	.	790	.	.	.	.	.	.	.	.	.	800	.	.	.	.	.	.	.	.	.	810	.	.	.	.	.	.	.	.	.	820	.	.	.	.	.	.	.	.	.	830	.	.	.	.	.	.	.	.	.	840
Sequence	F	N	K	L	K	N	T	I	S	K	F	F	D	S	Q	G	Q	V	L	L	T	D	T	N	T	Q	F	V	E	Q	T	I	A	I	M	K	N	L	L	D	N	H	T	E	G	S	S	E	H	L	G	Q	A	S	I	E	T	M	M	L	N	L	V	R	Y	V	R	V	L	G
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)									T	T	S	B		T	T	S		B																							S			T	T						T	S	S															T	T
	.	.	.	.	.	.	.	.	.	850	.	.	.	.	.	.	.	.	.	860	.	.	.	.	.	.	.	.	.	870	.	.	.	.	.	.	.	.	.	880	.	.	.	.	.	.	.	.	.	890	.	.	.	.	.	.	.	.	.	900	.	.	.	.	.	.	.	.	.	910
Sequence	N	M	V	H	A	I	Q	I	K	T	K	L	C	Q	L	V	E	V	M	M	A	R	R	D	D	L	S	F	C	Q	E	M	K	F	R	N	K	M	V	E	Y	L	T	D	W	V	M	G	T	S	N	Q	A	A	D	D	D	V	K	C	L	T	R	D	L	D	Q	A	S	M
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	S	S																				T	T	T	T	S			S														T	T	T	S	S	S	S	T	T	T			S
	.	.	.	.	.	.	.	.	.	920	.	.	.	.	.	.	.	.	.	930	.	.	.	.	.	.	.	.	.	940	.	.	.	.	.	.	.	.	.	950	.	.	.	.	.	.	.	.	.	960	.	.	.	.	.	.	.	.	.	970	.	.	.	.	.	.	.	.	.	980
Sequence	E	A	V	V	S	L	L	A	G	L	P	L	Q	P	E	E	G	D	G	V	E	L	M	E	A	K	S	Q	L	F	L	K	Y	F	T	L	F	M	N	L	L	N	D	C	S	E	M	S	R	R	L	A	S	L	R	H	C	T	V	L	A	M	S	N	L	L	N	A	N	V
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)								T	T						S			S	S																								T	S				T	T																					G
	.	.	.	.	.	.	.	.	.	990	.	.	.	.	.	.	.	.	.	1000	.	.	.	.	.	.	.	.	.	1010	.	.	.	.	.	.	.	.	.	1020	.	.	.	.	.	.	.	.	.	1030	.	.	.	.	.	.	.	.	.	1040	.	.	.	.	.	.	.	.	.	1050
Sequence	D	S	G	L	M	H	S	I	G	L	G	Y	H	K	D	L	Q	T	R	A	T	F	M	E	V	L	T	K	I	L	Q	Q	G	T	E	F	D	T	L	V	E	L	V	T	M	M	G	D	Q	G	E	L	P	I	A	M	A	L	A	N	V	V	P	C	S	Q	W	D	E	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	G	G	T					G	G	G	G	S			S	S	S	S									T	T	T	T	G	G	G	T	T							S						T		T	T											S		G	G	G
	.	.	.	.	.	.	.	.	.	1060	.	.	.	.	.	.	.	.	.	1070	.	.	.	.	.	.	.	.	.	1080	.	.	.	.	.	.	.	.	.	1090	.	.	.	.	.	.	.	.	.	1100	.	.	.	.	.	.	.	.	.	1110	.	.	.	.	.	.	.	.	.	1120
Sequence	A	R	V	L	V	T	L	F	D	S	R	H	L	L	Y	Q	L	L	W	N	M	F	S	K	E	V	E	L	A	D	S	M	Q	T	L	F	R	G	N	S	L	A	S	K	I	M	T	F	C	F	K	V	Y	G	A	T	Y	L	Q	K	L	L	D	P	L	S	L	E	E	N
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)									T	T	T	T										T	T							S	G	G	G	S	T	T		S	S	S	T	T	T	T	T									T	T	T	T					S	S				T	T	G	G
	.	.	.	.	.	.	.	.	.	1130	.	.	.	.	.	.	.	.	.	1140	.	.	.	.	.	.	.	.	.	1150	.	.	.	.	.	.	.	.	.	1160	.	.	.	.	.	.	.	.	.	1170	.	.	.	.	.	.	.	.	.	1180	.	.	.	.	.	.	.	.	.	1190
Sequence	Q	R	N	L	L	Q	M	T	E	K	F	F	H	A	I	I	S	S	S	S	E	F	P	P	Q	L	R	S	V	C	H	C	L	Y	Q	V	V	S	Q	R	F	P	Q	N	S	I	G	A	V	G	S	A	M	F	L	R	F	I	N	P	A	I	V	S	P	Y	E	A	P	R
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	G	T	T															T	T	T	T																						S		S	S												T	T	T	T	T	T		S	S
	.	.	.	.	.	.	.	.	.	1200	.	.	.	.	.	.	.	.	.	1210	.	.	.	.	.	.	.	.	.	1220	.	.	.	.	.	.	.	.	.	1230	.	.	.	.	.	.	.	.	.	1240	.	.	.	.	.	.	.	.	.	1250	.	.	.	.	.	.	.	.	.	1260
Sequence	I	E	R	G	L	K	L	M	S	K	I	L	Q	S	I	A	N	H	H	M	R	P	F	N	D	F	V	K	S	N	F	D	A	A	R	R	F	F	L	D	I	A	S	H	R	L	L	W	N	N	Q	E	K	I	G	Q	Y	L	S	S	R	P	F	D	K	M	A	T	L	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																					S	G	G	G	G	T	G	G	G	G	T	T																		T									T				S	S					T	T
	.	.	.	.	.	.	.	.	.	1270	.	.	.	.	.	.	.	.	.	1280	.	.	.	.	.	.	.	.	.	1290	.	.	.	.	.	.	.	.	.	1300	.	.	.	.	.	.	.	.	.	1310	.	.	.	.	.	.	.	.	.	1320	.	.	.	.	.	.	.	.	.	1330
Sequence	A	Y	L	G	P	P	E	K	E	E	F	K	A	L	K	T	L	S	I	F	Y	Q	A	G	T	S	K	A	G	N	P	I	F	Y	Y	V	A	R	R	F	K	T	G	Q	I	N	G	D	L	L	I	Y	H	V	L	L	T	L	K	P	Y	Y	A	K	P	Y	E	I	V	V
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T	T										S	S	T	T	T	T									B	T	T	S								G	G	G			T	T	T	S												T	T	T	T	T	T	T	S
	.	.	.	.	.	.	.	.	.	1340	.	.	.	.	.	.	.	.	.	1350	.	.	.	.	.	.	.	.	.	1360	.	.	.	.	.	.	.	.	.	1370	.	.	.	.	.	.	.	.	.	1380	.	.	.	.	.	.	.	.	.	1390	.	.	.	.	.	.	.	.	.	1400
Sequence	D	L	T	H	T	G	P	S	N	R	F	K	T	D	F	L	S	K	W	F	V	V	F	P	G	F	A	Y	D	N	V	S	A	V	Y	I	Y	N	C	N	S	W	V	R	E	Y	T	K	Y	H	E	R	L	L	T	G	L	K	G	S	K	R	L	V	F	I	D	C	P	G
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			T	T			G	G	G														S															S												T	T	T	T	S	T	T	T	T	T		T	T					S	S
	.	.	.	.	.	.	.	.	.	1410	.	.	.	.	.	.	.	.	.	1420	.	.	.	.	.	.	.	.	.	1430	.	.	.	.	.	.	.	.	.	1440	.	.	.	.	.	.	.	.	.	1450	.	.	.	.	.	.	.	.	.	1460	.	.	.	.	.	.	.	.	.	1470
Sequence	K	L	A	E	H	I	E	H	E	Q	Q	K	L	P	A	A	T	L	A	L	E	E	D	L	K	V	F	H	N	A	L	K	L	A	H	K	D	T	K	V	S	I	K	V	G	S	T	A	V	Q	V	T	S	A	E	R	T	K	V	L	G	Q	S	V	F	L	N	D	I	Y
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)					T	B	G	G	G										T	T	S	T	T					T	T					S	S	S										S	S								S					T	T
	.	.	.	.	.	.	.	.	.	1480	.	.	.	.	.	.	.	.	.	1490	.	.	.	.	.	.	.	.	.	1500	.	.	.	.	.	.	.	.	.	1510	.	.	.	.	.	.	.	.	.	1520	.	.	.	.	.	.	.	.	.	1530	.	.	.	.	.	.	.	.	.	1540
Sequence	Y	A	S	E	I	E	E	I	C	L	V	D	E	N	Q	F	T	L	T	I	A	N	Q	G	T	P	L	T	F	M	H	Q	E	C	E	A	I	V	Q	S	I	I	H	I	R	T	R	W	E	L	S	Q	P	D	I	R	P	K	D	V	P	G	T	L	L	N	I	A	L	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)		G	G	G									S	S							T	T		S								T	T																		T						S	S	S
	.	.	.	.	.	.	.	.	.	1550	.	.	.	.	.	.	.	.	.	1560	.	.	.	.	.	.	.	.	.	1570	.	.	.	.	.	.	.	.	.	1580	.	.	.	.	.	.	.	.	.	1590	.	.	.	.	.	.	.	.	.	1600	.	.	.	.	.	.	.	.	.	1610
Sequence	N	L	G	S	S	D	P	S	L	R	S	A	A	Y	N	L	L	C	A	L	T	C	T	F	N	L	K	I	E	G	Q	L	L	E	T	S	G	L	C	I	P	A	N	N	T	L	F	I	V	S	I	S	K	T	L	A	A	N	E	P	H	L	T	L	E	F	L	E	E	C
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			T		S																				T			S	T	T						S	S					S																			S		S	S
	.	.	.	.	.	.	.	.	.	1620	.	.	.	.	.	.	.	.	.	1630	.	.	.	.	.	.	.	.	.	1640	.	.	.	.	.	.	.	.	.	1650	.	.	.	.	.	.	.	.	.	1660	.	.	.	.	.	.	.	.	.	1670	.	.	.	.	.	.	.	.	.	1680
Sequence	I	S	G	F	S	K	S	S	I	E	L	K	H	L	C	L	E	Y	M	T	P	W	L	S	N	L	V	R	F	C	K	H	N	D	D	A	K	R	Q	R	V	T	A	I	L	D	K	L	I	T	M	T	I	N	E	K	Q	M	Y	P	S	I	Q	A	K	I	W	G	S	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)							S																	G	G	G	G					S																									T	T
	.	.	.	.	.	.	.	.	.	1690	.	.	.	.	.	.	.	.	.	1700	.	.	.	.	.	.	.	.	.	1710	.	.	.	.	.	.	.	.	.	1720	.	.	.	.	.	.	.	.	.	1730	.	.	.	.	.	.	.	.	.	1740	.	.	.	.	.	.	.	.	.	1750
Sequence	G	Q	I	T	D	L	L	D	V	V	L	D	S	F	I	K	T	S	A	T	G	G	L	G	S	I	K	A	E	V	M	A	D	T	A	V	A	L	A	S	G	N	V	K	L	V	S	S	K	V	I	G	R	M	C	K	I	I	D	K	T	C	L	S	P	T	P	T	L	E
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T	T		G	G	G																	T	T	S																																				G	G	G	S			S	S	S	T
	.	.	.	.	.	.	.	.	.	1760	.	.	.	.	.	.	.	.	.	1770	.	.	.	.	.	.	.	.	.	1780	.	.	.	.	.	.	.	.	.	1790	.	.	.	.	.	.	.	.	.	1800	.	.	.	.	.	.	.	.	.	1810	.	.	.	.	.	.	.	.	.	1820
Sequence	Q	H	L	M	W	D	D	I	A	I	L	A	R	Y	M	L	M	L	S	F	N	N	S	L	D	V	A	A	H	L	P	Y	L	F	H	V	V	T	F	L	V	A	T	G	P	L	S	L	R	A	S	T	H	G	L	V	I	N	I	I	H	S	L	C	T	C	S	Q	L	H
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T	S	T	T																G	G	G	T	T																	T	T		S	S																			T	T		T	T	S
	.	.	.	.	.	.	.	.	.	1830	.	.	.	.	.	.	.	.	.	1840	.	.	.	.	.	.	.	.	.	1850	.	.	.	.	.	.	.	.	.	1860	.	.	.	.	.	.	.	.	.	1870	.	.	.	.	.	.	.	.	.	1880	.	.	.	.	.	.	.	.	.	1890
Sequence	F	S	E	E	T	K	Q	V	L	R	L	S	L	T	E	F	S	L	P	K	F	Y	L	L	F	G	I	S	K	V	K	S	A	A	V	I	A	F	R	S	E	T	F	A	L	T	S	L	E	T	V	T	E	A	L	L	E	I	M	E	A	C	M	R	D	I	P	T	C	K
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																T	T	S							T	T			S		S							S																										T	T		T	T
	.	.	.	.	.	.	.	.	.	1900	.	.	.	.	.	.	.	.	.	1910	.	.	.	.	.	.	.	.	.	1920	.	.	.	.	.	.	.	.	.	1930	.	.	.	.	.	.	.	.	.	1940	.	.	.	.	.	.	.	.	.	1950	.	.	.	.	.	.	.	.	.	1960
Sequence	W	L	D	Q	W	T	E	L	A	Q	R	F	A	F	Q	Y	N	P	S	L	Q	P	R	A	L	V	V	F	G	C	I	S	K	R	V	S	H	G	Q	I	K	Q	I	I	R	I	L	S	K	A	L	E	S	C	L	K	G	P	D	T	Y	N	S	Q	V	L	I	E	A	T
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)														S	S			S	S														S																									S
	.	.	.	.	.	.	.	.	.	1970	.	.	.	.	.	.	.	.	.	1980	.	.	.	.	.	.	.	.	.	1990	.	.	.	.	.	.	.	.	.	2000	.	.	.	.	.	.	.	.	.	2010	.	.	.	.	.	.	.	.	.	2020	.	.	.	.	.	.	.	.	.	2030
Sequence	V	I	A	L	T	K	L	Q	P	L	L	N	K	D	S	P	L	H	K	A	L	F	W	V	A	V	A	V	L	Q	L	D	E	V	N	L	Y	S	A	G	T	A	L	L	E	Q	N	L	H	T	L	D	S	L	R	I	F	N	D	K	S	P	E	E	V	F	M	A	I	R
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)								G	G	G	S		T	T		T															T																							T	T		S	S	S	S
	.	.	.	.	.	.	.	.	.	2040	.	.	.	.	.	.	.	.	.	2050	.	.	.	.	.	.	.	.	.	2060	.	.	.	.	.	.	.	.	.	2070	.	.	.	.	.	.	.	.	.	2080	.	.	.	.	.	.	.	.	.	2090	.	.	.	.	.	.	.	.	.	2100
Sequence	N	P	L	E	W	H	C	K	Q	M	D	H	F	V	G	L	N	F	N	S	N	F	N	F	A	L	V	G	H	L	L	K	G	Y	R	H	P	S	P	A	I	V	A	R	T	V	R	I	L	H	T	L	L	T	L	V	N	K	H	R	N	C	D	K	F	E	V	N	T	Q
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	G	G	G												T			T	T	T											T						S	S																						T	T			T	T				T	T
	.	.	.	.	.	.	.	.	.	2110	.	.	.	.	.	.	.	.	.	2120	.	.	.	.	.	.	.	.	.	2130	.	.	.	.	.	.	.	.	.	2140	.	.	.	.	.	.	.	.	.	2150	.	.	.	.	.	.	.	.	.	2160	.	.	.	.	.	.	.	.	.	2170
Sequence	S	V	A	Y	L	A	A	L	L	T	V	S	E	E	V	R	S	R	C	V	L	L	D	E	E	V	L	T	D	P	K	I	Q	A	L	L	L	T	V	L	A	T	L	V	K	Y	T	T	D	E	F	D	Q	R	I	L	Y	E	Y	L	A	E	A	S	V	V	F	P	K	V
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)										T	T											S		T	T	T	T	T	S																	S																						T	T	T
	.	.	.	.	.	.	.	.	.	2180	.	.	.	.	.	.	.	.	.	2190	.	.	.	.	.	.	.	.	.	2200	.	.	.	.	.	.	.	.	.	2210	.	.	.	.	.	.	.	.	.	2220	.	.	.	.	.	.	.	.	.	2230	.	.	.	.	.	.	.	.	.	2240
Sequence	F	P	V	V	H	N	L	L	D	S	K	I	N	T	L	L	S	L	C	Q	D	P	N	L	L	N	P	I	H	G	I	V	Q	S	V	V	Y	H	E	E	S	P	P	Q	Y	Q	T	S	Y	L	Q	S	F	G	F	N	G	L	W	R	F	A	G	P	F	S	K	Q	T	Q
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T	T	T	T																																							G	G	G	T						T	T	T		G	G	G	G	T	T	T	S				S	S	S	S
	.	.	.	.	.	.	.	.	.	2250	.	.	.	.	.	.	.	.	.	2260
Sequence	I	P	D	Y	A	E	L	I	V	K	F	L	D	A	L	I	D	T	Y	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T	T	T	T