|Protein Homology/analogY Recognition Engine V 2.0
You must login to use expert mode
|Submit both a sequence and a structure. Phyre will attempt to align the sequence and structure and construct a model of your sequence
|Submit a file containing up to 100 sequences for automated modelling by Phyre (to increase limit contact Harry Powell)
|Use Phyre in reverse. Submit a PDB structure and search that structure against a wide range of genomes
|Search your sequence against a wide range of genomes
5651661 submissions since Feb 14 2011
Missense3D Portal: a suite of resources for the analysis of amino acid substitutions in proteins
GWYRE: contains modeled and experimentally determined structures of human proteins and protein complexes, annotated by phenotypic effects of genetic mutations.
Cambridge 2019 Workshop | Older Workshops | Phyre2 paper
Phyre is now FREE for commercial users!
All images and data generated by Phyre2 are free to use in any publication with acknowledgementAccessibility Statement
|Please cite: The Phyre2 web portal for protein modeling, prediction and analysis
|Kelley LA et al. Nature Protocols 10, 845-858 (2015) [paper] [Citation link]