PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c7t3uA_

Fold library id	PDB Header	Molecule	Title
c7t3uA_	3.70	PDB header: metal transport	Chain: A: PDB Molecule: inositol 1,4,5-trisphosphate receptor type 3;

Links to external resources
Added to library: 3.70

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence S S F L H I G D I V S L Y A E G S V N G F I S T L G L V D D R C V V E P A A G D L D N P P K K F R D C L F K V C P M N R Y S A Q K Q Y W K A

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
B T T
S S S
S T T
B
T T T
S S S
T T G G G G

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence K Q T D V V L L Q K L Q H A A Q M E Q K Q N D T E N K K V H G D V V K Y G S V I Q L L H M K S N K Y L T V N K R L P A L L E K N A M R V T L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T T
B
B T T
T T T T
S S
T T

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence D A T G N E G S W L F I Q P F W K L R S N G D N V V V G D K V I L N P V N A G Q P L H A S N Y E L S D N A G C K E V N S V N C N T S W K I N

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S S
S
T T S S S
T T S B
T T
B
S S S
S
B
S S S T T
B
S S

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240 . . . . . . . . . 250 . . . . . . . . . 260 . . . . . . . . . 270 . . . . . . . . . 280

Sequence L F M Q F V L K G G D V V R L F H A E Q E K F L T C D E Y K G K L Q V F L R T T L R Q S A T S A T S S N A L W E V E V V H L Y R F K H L A T

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S
T T T T T T
S
S T T
S S
T T T

. . . . . . . . . 290 . . . . . . . . . 300 . . . . . . . . . 310 . . . . . . . . . 320 . . . . . . . . . 330 . . . . . . . . . 340 . . . . . . . . . 350

Sequence G N Y L A A E E N K Y C L V A V P H G N D I A S L F E L D P T Y V R L R H L C T N T W I Q S T N V P I D I E E E R P I R L M L G T C P T K E

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S
T T
S S
T T T
S
S S S S
S S

. . . . . . . . . 360 . . . . . . . . . 370 . . . . . . . . . 380 . . . . . . . . . 390 . . . . . . . . . 400 . . . . . . . . . 410 . . . . . . . . . 420

Sequence D K E A F A I V S V P V S E I R D L D F A N D A S S M L A S A V E K L N E G F I S Q N D R R F V I Q L L E D L V F F V S D V P N N G Q N V L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T S
S
T
S S
G G

. . . . . . . . . 430 . . . . . . . . . 440 . . . . . . . . . 450 . . . . . . . . . 460 . . . . . . . . . 470 . . . . . . . . . 480 . . . . . . . . . 490

Sequence D I M V T K P N R E R Q K L M R E Q N I L K Q V F G I L K A P F R P L V R L E E L S D Q K N A P Y Q H M F R L C Y R V L R H S Q E D Y R K N

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) G
S S
T T
S S S
S S S S S T S S S

. . . . . . . . . 500 . . . . . . . . . 510 . . . . . . . . . 520 . . . . . . . . . 530 . . . . . . . . . 540 . . . . . . . . . 550 . . . . . . . . . 560

Sequence Q E H I A K Q F G M M Q S Q I G Y D I L A E D T I T A L L H N N R K L L E K H I T K T E V E T F V S L V R K N R E P R F L D Y L S D L C V S

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T
S
S S S S T T T T S
S S

. . . . . . . . . 570 . . . . . . . . . 580 . . . . . . . . . 590 . . . . . . . . . 600 . . . . . . . . . 610 . . . . . . . . . 620 . . . . . . . . . 630

Sequence N H I A I P V T Q E L I C K C V L D P K N S D I L I R T E L R P E V W L T W T D K N N E H H E K S V R Q L A Q E A R A G N A H D E N V L S Y

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T T
S T T T T T S S
T T T T

. . . . . . . . . 640 . . . . . . . . . 650 . . . . . . . . . 660 . . . . . . . . . 670 . . . . . . . . . 680 . . . . . . . . . 690 . . . . . . . . . 700

Sequence Y R Y Q L K L F A R M C L D R Q Y L A I D E I S Q Q L G V D L I F L C M A D E M L P F D L R A S F C H L M L H V H V D R D P Q E L V T P V K

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T T T
S
T T S S S
T S S S S
S S

. . . . . . . . . 710 . . . . . . . . . 720 . . . . . . . . . 730 . . . . . . . . . 740 . . . . . . . . . 750 . . . . . . . . . 760 . . . . . . . . . 770

Sequence F A R L W T E I P T A I T I K D Y D S N L N N K F A N T M E F V E D Y L N N V V S E A V P F A N E E K N K L T F E V V S L A H N L I Y F G F

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S
T T T S
S
T T T T
S S S S S S
T T

. . . . . . . . . 780 . . . . . . . . . 790 . . . . . . . . . 800 . . . . . . . . . 810 . . . . . . . . . 820 . . . . . . . . . 830 . . . . . . . . . 840

Sequence Y S F S E L L R L T R T L L G I I D C D I V V M E T K L K I L E I L Q F I L N V R L D Y R I S Y L L S V F K K E F L D R I G E Q A E A M F G

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S
T T
T

. . . . . . . . . 850 . . . . . . . . . 860 . . . . . . . . . 870 . . . . . . . . . 880 . . . . . . . . . 890 . . . . . . . . . 900 . . . . . . . . . 910

Sequence S M L E V D D E G G R M F L R V L I H L T M H D Y A P L V S G A L Q L L F K H F S Q R Q E A M H T F K Q V Q L L I S A Q D V E N Y K V I K S

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S
S
S S T T T S S
T T T T
S S

. . . . . . . . . 920 . . . . . . . . . 930 . . . . . . . . . 940 . . . . . . . . . 950 . . . . . . . . . 960 . . . . . . . . . 970 . . . . . . . . . 980

Sequence E L D R L R T M V E K N Y Q I V K G I L E R L N K M C Q M R K K Q Q R L L K N M D A H K V M L D L L Q I P Y D K G D A K M M E I L R Y T H Q

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T S
S S

. . . . . . . . . 990 . . . . . . . . . 1000 . . . . . . . . . 1010 . . . . . . . . . 1020 . . . . . . . . . 1030 . . . . . . . . . 1040 . . . . . . . . . 1050

Sequence F L Q K F C A G N P G N Q A L L H K H L H L F L T P G L L E A E T M Q H I F L N N Y Q L C S E I S E P V L Q H F V H L L A T H G R H V Q Y L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T S
S
T
S S S T S S
T
S

. . . . . . . . . 1060 . . . . . . . . . 1070 . . . . . . . . . 1080 . . . . . . . . . 1090 . . . . . . . . . 1100 . . . . . . . . . 1110 . . . . . . . . . 1120

Sequence D F L H T V I K A D M I M T E L T N A G D D V V V F Y N D K A S L A H L L D M M K A A R D G V E D H S P L M Y H I S L V D L L A A C A E G K

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T T T S
S T S S
S S S T S S

. . . . . . . . . 1130 . . . . . . . . . 1140 . . . . . . . . . 1150 . . . . . . . . . 1160 . . . . . . . . . 1170 . . . . . . . . . 1180 . . . . . . . . . 1190

Sequence N V Y T E I K C T S L L P L E D V V S V V T H E D C I T E V K M A Y V N F V N H I W T L F E N F T L D M A R V C S D P T L E K Y V L S V V L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S
T S T T
T T T T T S T T T
S T T

. . . . . . . . . 1200 . . . . . . . . . 1210 . . . . . . . . . 1220 . . . . . . . . . 1230 . . . . . . . . . 1240 . . . . . . . . . 1250 . . . . . . . . . 1260

Sequence D T I N A F F S S P F S E N S T S L Q T H Q T I V V Q L L Q S T T R L L E C P W L Q Q Q H K G S V E A C I R T L A M V K N I I E K L Q D I I

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S T T
T T S S
S T T T S T T
T T T T T
T

. . . . . . . . . 1270 . . . . . . . . . 1280 . . . . . . . . . 1290 . . . . . . . . . 1300 . . . . . . . . . 1310 . . . . . . . . . 1320 . . . . . . . . . 1330

Sequence T A L E E R L K P L V Q A E L S V L V D V L H W P E L L F L E G S E A Y Q R C E S G G F L S K L I Q H T K D L M E S E E K L C I K V L R T L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S G G G T S
T T S T T T S T T T T T

. . . . . . . . . 1340 . . . . . . . . . 1350 . . . . . . . . . 1360 . . . . . . . . . 1370 . . . . . . . . . 1380 . . . . . . . . . 1390 . . . . . . . . . 1400

Sequence Q Q M L L K K T K Y G D R G N Q L R K M L L Q N Y L Q S A I A A T Q C R L D K E G A T K L V C D L I T S T K N E K I F Q E S I G L A I H L L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T S
T T T
T S

. . . . . . . . . 1410 . . . . . . . . . 1420 . . . . . . . . . 1430 . . . . . . . . . 1440 . . . . . . . . . 1450 . . . . . . . . . 1460 . . . . . . . . . 1470

Sequence D G G N T E I Q K S F H N L M M S D K K S E R F F K V L H D R M K R A Q Q E T T S V L I M Q P I L R F L Q L L C E N H N R D L Q N F L R C Q

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T
S T T S S S T T T
T T T
T T

. . . . . . . . . 1480 . . . . . . . . . 1490 . . . . . . . . . 1500 . . . . . . . . . 1510 . . . . . . . . . 1520 . . . . . . . . . 1530 . . . . . . . . . 1540

Sequence N N K T N Y N L V C E T L Q F L D I G L L G L Y I N E D N V G L V I Q T L E T L T E Y C Q G P C H E N Q T C I V T H E S N G I D I I T A L I

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T S S S
S
T T T T T S
T T S S S S
S
T T

. . . . . . . . . 1550 . . . . . . . . . 1560 . . . . . . . . . 1570 . . . . . . . . . 1580 . . . . . . . . . 1590 . . . . . . . . . 1600 . . . . . . . . . 1610

Sequence L N D L V L Q L K D N A S K L L L A L M E S N A E R I L I S L R P Q E L V D V I K K A Y L V S P R E V G H N I Y I L A L Q L S R H N K Q L Q

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T
S
T
T T
S

. . . . . . . . . 1620 . . . . . . . . . 1630 . . . . . . . . . 1640 . . . . . . . . . 1650 . . . . . . . . . 1660 . . . . . . . . . 1670 . . . . . . . . . 1680

Sequence H L L K P D P L A Y Y E N H T S Q I E I V R Q D R S M E Q I V F P V P G I C Q F L T E E T K H R L F T T T E Q D E Q G S K V S D F F D Q S S

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T
T S
B
T T S
B
G G G G
T
S S S
S

. . . . . . . . . 1690 . . . . . . . . . 1700 . . . . . . . . . 1710 . . . . . . . . . 1720 . . . . . . . . . 1730 . . . . . . . . . 1740 . . . . . . . . . 1750

Sequence F L H N E M E W Q R K L R S M P L I Y W F S R R M T L W G S I S F N L A V F I N I I I A F F Y P Y I R P L I V A L I L R S I Y Y L G I G P T

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S
S
T
T T

. . . . . . . . . 1760 . . . . . . . . . 1770 . . . . . . . . . 1780 . . . . . . . . . 1790 . . . . . . . . . 1800 . . . . . . . . . 1810 . . . . . . . . . 1820

Sequence L N I L G A L N L T N K I V F V V S F V G N R M E F L Y H V G Y I L T S V L G L F A H E L F Y S I L L F D L I Y R E E T L F N V I K S V T R

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T
T
G G G G G G G G T T
S T

. . . . . . . . . 1830 . . . . . . . . . 1840 . . . . . . . . . 1850 . . . . . . . . . 1860 . . . . . . . . . 1870 . . . . . . . . . 1880 . . . . . . . . . 1890

Sequence N G R S I L L T A L L A L I L V Y L F S I V G F L F L K D D F I L E V D R L S T E R A C D T L L M C I V T V M N H G L R N G G G V G D I L R

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T S T T S
S T T S T T T T S T T G G G G T S

. . . . . . . . . 1900 . . . . . . . . . 1910 . . . . . . . . . 1920 . . . . . . . . . 1930 . . . . . . . . . 1940 . . . . . . . . . 1950 . . . . . . . . . 1960

Sequence K P S K D E S L F P A R V V Y D L L F F F I V I I I V L N L I F G V I I D T F A D L R S E K Q K K E E I L K T T C F I C G L E R D K F D N K

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T S T T T T T S
T T T
S G G G S S S

. . . . . . . . . 1970 . . . . . . . . . 1980 . . . . . . . . . 1990 . . . . . . . . . 2000 . . . . . . . . . 2010

Sequence T V S F E E H I K L E H N M W N Y L Y F I V L V R V K N K T D Y T G P E S Y V A Q M I c 7 t 3 u A _

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S S
T T T T S
T T S
T T T
T T
S

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	S	S	F	L	H	I	G	D	I	V	S	L	Y	A	E	G	S	V	N	G	F	I	S	T	L	G	L	V	D	D	R	C	V	V	E	P	A	A	G	D	L	D	N	P	P	K	K	F	R	D	C	L	F	K	V	C	P	M	N	R	Y	S	A	Q	K	Q	Y	W	K	A
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)					B	T	T									S	S	S								S	T	T						B		T	T	T			S	S	S			T	T	G	G	G	G
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	K	Q	T	D	V	V	L	L	Q	K	L	Q	H	A	A	Q	M	E	Q	K	Q	N	D	T	E	N	K	K	V	H	G	D	V	V	K	Y	G	S	V	I	Q	L	L	H	M	K	S	N	K	Y	L	T	V	N	K	R	L	P	A	L	L	E	K	N	A	M	R	V	T	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																													T	T	T		B		B	T	T								T	T	T	T												S	S		T	T
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	D	A	T	G	N	E	G	S	W	L	F	I	Q	P	F	W	K	L	R	S	N	G	D	N	V	V	V	G	D	K	V	I	L	N	P	V	N	A	G	Q	P	L	H	A	S	N	Y	E	L	S	D	N	A	G	C	K	E	V	N	S	V	N	C	N	T	S	W	K	I	N
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)		S	S			S									T	T	S	S	S		T	T	S	B			T	T		B						S	S	S								S		B		S	S	S	T	T		B					S	S
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280
Sequence	L	F	M	Q	F	V	L	K	G	G	D	V	V	R	L	F	H	A	E	Q	E	K	F	L	T	C	D	E	Y	K	G	K	L	Q	V	F	L	R	T	T	L	R	Q	S	A	T	S	A	T	S	S	N	A	L	W	E	V	E	V	V	H	L	Y	R	F	K	H	L	A	T
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)									S	S								T	T	T	T									T	T												S		S	T	T				S	S																T	T	T
	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350
Sequence	G	N	Y	L	A	A	E	E	N	K	Y	C	L	V	A	V	P	H	G	N	D	I	A	S	L	F	E	L	D	P	T	Y	V	R	L	R	H	L	C	T	N	T	W	I	Q	S	T	N	V	P	I	D	I	E	E	E	R	P	I	R	L	M	L	G	T	C	P	T	K	E
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																	S		T	T		S	S															T	T	T											S			S	S	S	S										S	S
	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence	D	K	E	A	F	A	I	V	S	V	P	V	S	E	I	R	D	L	D	F	A	N	D	A	S	S	M	L	A	S	A	V	E	K	L	N	E	G	F	I	S	Q	N	D	R	R	F	V	I	Q	L	L	E	D	L	V	F	F	V	S	D	V	P	N	N	G	Q	N	V	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T	T	S																																			S																							T					S	S		G	G
	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490
Sequence	D	I	M	V	T	K	P	N	R	E	R	Q	K	L	M	R	E	Q	N	I	L	K	Q	V	F	G	I	L	K	A	P	F	R	P	L	V	R	L	E	E	L	S	D	Q	K	N	A	P	Y	Q	H	M	F	R	L	C	Y	R	V	L	R	H	S	Q	E	D	Y	R	K	N
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	G				S	S												T	T																			S	S	S		S	S	S	S	S																	T	S	S	S
	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560
Sequence	Q	E	H	I	A	K	Q	F	G	M	M	Q	S	Q	I	G	Y	D	I	L	A	E	D	T	I	T	A	L	L	H	N	N	R	K	L	L	E	K	H	I	T	K	T	E	V	E	T	F	V	S	L	V	R	K	N	R	E	P	R	F	L	D	Y	L	S	D	L	C	V	S
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)							T							S		S	S	S	S	T	T								T	T	S																																						S	S
	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630
Sequence	N	H	I	A	I	P	V	T	Q	E	L	I	C	K	C	V	L	D	P	K	N	S	D	I	L	I	R	T	E	L	R	P	E	V	W	L	T	W	T	D	K	N	N	E	H	H	E	K	S	V	R	Q	L	A	Q	E	A	R	A	G	N	A	H	D	E	N	V	L	S	Y
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T	T	T															S	T	T	T	T	T	S	S															T	T	T	T
	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.	.	660	.	.	.	.	.	.	.	.	.	670	.	.	.	.	.	.	.	.	.	680	.	.	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700
Sequence	Y	R	Y	Q	L	K	L	F	A	R	M	C	L	D	R	Q	Y	L	A	I	D	E	I	S	Q	Q	L	G	V	D	L	I	F	L	C	M	A	D	E	M	L	P	F	D	L	R	A	S	F	C	H	L	M	L	H	V	H	V	D	R	D	P	Q	E	L	V	T	P	V	K
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)												T	T	T	T												S										T	T	S	S	S																	T	S	S	S	S						S	S
	.	.	.	.	.	.	.	.	.	710	.	.	.	.	.	.	.	.	.	720	.	.	.	.	.	.	.	.	.	730	.	.	.	.	.	.	.	.	.	740	.	.	.	.	.	.	.	.	.	750	.	.	.	.	.	.	.	.	.	760	.	.	.	.	.	.	.	.	.	770
Sequence	F	A	R	L	W	T	E	I	P	T	A	I	T	I	K	D	Y	D	S	N	L	N	N	K	F	A	N	T	M	E	F	V	E	D	Y	L	N	N	V	V	S	E	A	V	P	F	A	N	E	E	K	N	K	L	T	F	E	V	V	S	L	A	H	N	L	I	Y	F	G	F
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	S				T	T	T	S		S				T	T					T	T																				S	S	S	S	S	S																						T	T
	.	.	.	.	.	.	.	.	.	780	.	.	.	.	.	.	.	.	.	790	.	.	.	.	.	.	.	.	.	800	.	.	.	.	.	.	.	.	.	810	.	.	.	.	.	.	.	.	.	820	.	.	.	.	.	.	.	.	.	830	.	.	.	.	.	.	.	.	.	840
Sequence	Y	S	F	S	E	L	L	R	L	T	R	T	L	L	G	I	I	D	C	D	I	V	V	M	E	T	K	L	K	I	L	E	I	L	Q	F	I	L	N	V	R	L	D	Y	R	I	S	Y	L	L	S	V	F	K	K	E	F	L	D	R	I	G	E	Q	A	E	A	M	F	G
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	S															T	T																																																				T
	.	.	.	.	.	.	.	.	.	850	.	.	.	.	.	.	.	.	.	860	.	.	.	.	.	.	.	.	.	870	.	.	.	.	.	.	.	.	.	880	.	.	.	.	.	.	.	.	.	890	.	.	.	.	.	.	.	.	.	900	.	.	.	.	.	.	.	.	.	910
Sequence	S	M	L	E	V	D	D	E	G	G	R	M	F	L	R	V	L	I	H	L	T	M	H	D	Y	A	P	L	V	S	G	A	L	Q	L	L	F	K	H	F	S	Q	R	Q	E	A	M	H	T	F	K	Q	V	Q	L	L	I	S	A	Q	D	V	E	N	Y	K	V	I	K	S
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			S		S		S	S	T	T												T	S	S																T	T										T	T						S	S
	.	.	.	.	.	.	.	.	.	920	.	.	.	.	.	.	.	.	.	930	.	.	.	.	.	.	.	.	.	940	.	.	.	.	.	.	.	.	.	950	.	.	.	.	.	.	.	.	.	960	.	.	.	.	.	.	.	.	.	970	.	.	.	.	.	.	.	.	.	980
Sequence	E	L	D	R	L	R	T	M	V	E	K	N	Y	Q	I	V	K	G	I	L	E	R	L	N	K	M	C	Q	M	R	K	K	Q	Q	R	L	L	K	N	M	D	A	H	K	V	M	L	D	L	L	Q	I	P	Y	D	K	G	D	A	K	M	M	E	I	L	R	Y	T	H	Q
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																																									T											S				S	S
	.	.	.	.	.	.	.	.	.	990	.	.	.	.	.	.	.	.	.	1000	.	.	.	.	.	.	.	.	.	1010	.	.	.	.	.	.	.	.	.	1020	.	.	.	.	.	.	.	.	.	1030	.	.	.	.	.	.	.	.	.	1040	.	.	.	.	.	.	.	.	.	1050
Sequence	F	L	Q	K	F	C	A	G	N	P	G	N	Q	A	L	L	H	K	H	L	H	L	F	L	T	P	G	L	L	E	A	E	T	M	Q	H	I	F	L	N	N	Y	Q	L	C	S	E	I	S	E	P	V	L	Q	H	F	V	H	L	L	A	T	H	G	R	H	V	Q	Y	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)					T	S		S											T						S	S	S											T	S	S							T																		S
	.	.	.	.	.	.	.	.	.	1060	.	.	.	.	.	.	.	.	.	1070	.	.	.	.	.	.	.	.	.	1080	.	.	.	.	.	.	.	.	.	1090	.	.	.	.	.	.	.	.	.	1100	.	.	.	.	.	.	.	.	.	1110	.	.	.	.	.	.	.	.	.	1120
Sequence	D	F	L	H	T	V	I	K	A	D	M	I	M	T	E	L	T	N	A	G	D	D	V	V	V	F	Y	N	D	K	A	S	L	A	H	L	L	D	M	M	K	A	A	R	D	G	V	E	D	H	S	P	L	M	Y	H	I	S	L	V	D	L	L	A	A	C	A	E	G	K
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																				T	T	T	T	S					S														T	S	S				S	S	S																T	S	S
	.	.	.	.	.	.	.	.	.	1130	.	.	.	.	.	.	.	.	.	1140	.	.	.	.	.	.	.	.	.	1150	.	.	.	.	.	.	.	.	.	1160	.	.	.	.	.	.	.	.	.	1170	.	.	.	.	.	.	.	.	.	1180	.	.	.	.	.	.	.	.	.	1190
Sequence	N	V	Y	T	E	I	K	C	T	S	L	L	P	L	E	D	V	V	S	V	V	T	H	E	D	C	I	T	E	V	K	M	A	Y	V	N	F	V	N	H	I	W	T	L	F	E	N	F	T	L	D	M	A	R	V	C	S	D	P	T	L	E	K	Y	V	L	S	V	V	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)												S										T	S	T	T																T	T	T								T	T	S	T	T	T				S	T	T
	.	.	.	.	.	.	.	.	.	1200	.	.	.	.	.	.	.	.	.	1210	.	.	.	.	.	.	.	.	.	1220	.	.	.	.	.	.	.	.	.	1230	.	.	.	.	.	.	.	.	.	1240	.	.	.	.	.	.	.	.	.	1250	.	.	.	.	.	.	.	.	.	1260
Sequence	D	T	I	N	A	F	F	S	S	P	F	S	E	N	S	T	S	L	Q	T	H	Q	T	I	V	V	Q	L	L	Q	S	T	T	R	L	L	E	C	P	W	L	Q	Q	Q	H	K	G	S	V	E	A	C	I	R	T	L	A	M	V	K	N	I	I	E	K	L	Q	D	I	I
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)									S	T	T		T	T	S	S		S					T									T					T	S	T	T			T												T	T	T	T			T
	.	.	.	.	.	.	.	.	.	1270	.	.	.	.	.	.	.	.	.	1280	.	.	.	.	.	.	.	.	.	1290	.	.	.	.	.	.	.	.	.	1300	.	.	.	.	.	.	.	.	.	1310	.	.	.	.	.	.	.	.	.	1320	.	.	.	.	.	.	.	.	.	1330
Sequence	T	A	L	E	E	R	L	K	P	L	V	Q	A	E	L	S	V	L	V	D	V	L	H	W	P	E	L	L	F	L	E	G	S	E	A	Y	Q	R	C	E	S	G	G	F	L	S	K	L	I	Q	H	T	K	D	L	M	E	S	E	E	K	L	C	I	K	V	L	R	T	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																								S	G	G	G	T	S		T	T	S						T	T	T	S												T	T	T	T	T
	.	.	.	.	.	.	.	.	.	1340	.	.	.	.	.	.	.	.	.	1350	.	.	.	.	.	.	.	.	.	1360	.	.	.	.	.	.	.	.	.	1370	.	.	.	.	.	.	.	.	.	1380	.	.	.	.	.	.	.	.	.	1390	.	.	.	.	.	.	.	.	.	1400
Sequence	Q	Q	M	L	L	K	K	T	K	Y	G	D	R	G	N	Q	L	R	K	M	L	L	Q	N	Y	L	Q	S	A	I	A	A	T	Q	C	R	L	D	K	E	G	A	T	K	L	V	C	D	L	I	T	S	T	K	N	E	K	I	F	Q	E	S	I	G	L	A	I	H	L	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)				T	S																																				T										T	T																	T	S
	.	.	.	.	.	.	.	.	.	1410	.	.	.	.	.	.	.	.	.	1420	.	.	.	.	.	.	.	.	.	1430	.	.	.	.	.	.	.	.	.	1440	.	.	.	.	.	.	.	.	.	1450	.	.	.	.	.	.	.	.	.	1460	.	.	.	.	.	.	.	.	.	1470
Sequence	D	G	G	N	T	E	I	Q	K	S	F	H	N	L	M	M	S	D	K	K	S	E	R	F	F	K	V	L	H	D	R	M	K	R	A	Q	Q	E	T	T	S	V	L	I	M	Q	P	I	L	R	F	L	Q	L	L	C	E	N	H	N	R	D	L	Q	N	F	L	R	C	Q
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T	T																S	T	T													S	S	S	T	T	T																			T	T	T										T	T
	.	.	.	.	.	.	.	.	.	1480	.	.	.	.	.	.	.	.	.	1490	.	.	.	.	.	.	.	.	.	1500	.	.	.	.	.	.	.	.	.	1510	.	.	.	.	.	.	.	.	.	1520	.	.	.	.	.	.	.	.	.	1530	.	.	.	.	.	.	.	.	.	1540
Sequence	N	N	K	T	N	Y	N	L	V	C	E	T	L	Q	F	L	D	I	G	L	L	G	L	Y	I	N	E	D	N	V	G	L	V	I	Q	T	L	E	T	L	T	E	Y	C	Q	G	P	C	H	E	N	Q	T	C	I	V	T	H	E	S	N	G	I	D	I	I	T	A	L	I
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T	S	S	S				S												T	T	T	T	T	S		T	T	S																S	S	S										S		T	T
	.	.	.	.	.	.	.	.	.	1550	.	.	.	.	.	.	.	.	.	1560	.	.	.	.	.	.	.	.	.	1570	.	.	.	.	.	.	.	.	.	1580	.	.	.	.	.	.	.	.	.	1590	.	.	.	.	.	.	.	.	.	1600	.	.	.	.	.	.	.	.	.	1610
Sequence	L	N	D	L	V	L	Q	L	K	D	N	A	S	K	L	L	L	A	L	M	E	S	N	A	E	R	I	L	I	S	L	R	P	Q	E	L	V	D	V	I	K	K	A	Y	L	V	S	P	R	E	V	G	H	N	I	Y	I	L	A	L	Q	L	S	R	H	N	K	Q	L	Q
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																			T	T											S													T																				T	T		S
	.	.	.	.	.	.	.	.	.	1620	.	.	.	.	.	.	.	.	.	1630	.	.	.	.	.	.	.	.	.	1640	.	.	.	.	.	.	.	.	.	1650	.	.	.	.	.	.	.	.	.	1660	.	.	.	.	.	.	.	.	.	1670	.	.	.	.	.	.	.	.	.	1680
Sequence	H	L	L	K	P	D	P	L	A	Y	Y	E	N	H	T	S	Q	I	E	I	V	R	Q	D	R	S	M	E	Q	I	V	F	P	V	P	G	I	C	Q	F	L	T	E	E	T	K	H	R	L	F	T	T	T	E	Q	D	E	Q	G	S	K	V	S	D	F	F	D	Q	S	S
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			T										T	S							B		T	T	S		B									G	G	G	G													T					S	S	S		S
	.	.	.	.	.	.	.	.	.	1690	.	.	.	.	.	.	.	.	.	1700	.	.	.	.	.	.	.	.	.	1710	.	.	.	.	.	.	.	.	.	1720	.	.	.	.	.	.	.	.	.	1730	.	.	.	.	.	.	.	.	.	1740	.	.	.	.	.	.	.	.	.	1750
Sequence	F	L	H	N	E	M	E	W	Q	R	K	L	R	S	M	P	L	I	Y	W	F	S	R	R	M	T	L	W	G	S	I	S	F	N	L	A	V	F	I	N	I	I	I	A	F	F	Y	P	Y	I	R	P	L	I	V	A	L	I	L	R	S	I	Y	Y	L	G	I	G	P	T
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)															S																															S																			T		T	T
	.	.	.	.	.	.	.	.	.	1760	.	.	.	.	.	.	.	.	.	1770	.	.	.	.	.	.	.	.	.	1780	.	.	.	.	.	.	.	.	.	1790	.	.	.	.	.	.	.	.	.	1800	.	.	.	.	.	.	.	.	.	1810	.	.	.	.	.	.	.	.	.	1820
Sequence	L	N	I	L	G	A	L	N	L	T	N	K	I	V	F	V	V	S	F	V	G	N	R	M	E	F	L	Y	H	V	G	Y	I	L	T	S	V	L	G	L	F	A	H	E	L	F	Y	S	I	L	L	F	D	L	I	Y	R	E	E	T	L	F	N	V	I	K	S	V	T	R
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																						T																				T		G	G	G	G	G	G	G	G	T	T						S											T
	.	.	.	.	.	.	.	.	.	1830	.	.	.	.	.	.	.	.	.	1840	.	.	.	.	.	.	.	.	.	1850	.	.	.	.	.	.	.	.	.	1860	.	.	.	.	.	.	.	.	.	1870	.	.	.	.	.	.	.	.	.	1880	.	.	.	.	.	.	.	.	.	1890
Sequence	N	G	R	S	I	L	L	T	A	L	L	A	L	I	L	V	Y	L	F	S	I	V	G	F	L	F	L	K	D	D	F	I	L	E	V	D	R	L	S	T	E	R	A	C	D	T	L	L	M	C	I	V	T	V	M	N	H	G	L	R	N	G	G	G	V	G	D	I	L	R
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T																									T	S	T	T	S													S	T	T	S											T	T	T	T	S	T	T	G	G	G	G	T	S
	.	.	.	.	.	.	.	.	.	1900	.	.	.	.	.	.	.	.	.	1910	.	.	.	.	.	.	.	.	.	1920	.	.	.	.	.	.	.	.	.	1930	.	.	.	.	.	.	.	.	.	1940	.	.	.	.	.	.	.	.	.	1950	.	.	.	.	.	.	.	.	.	1960
Sequence	K	P	S	K	D	E	S	L	F	P	A	R	V	V	Y	D	L	L	F	F	F	I	V	I	I	I	V	L	N	L	I	F	G	V	I	I	D	T	F	A	D	L	R	S	E	K	Q	K	K	E	E	I	L	K	T	T	C	F	I	C	G	L	E	R	D	K	F	D	N	K
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)				T	T	S	T	T																T	T	T																														S		T	T	T				S	G	G	G	S	S	S
	.	.	.	.	.	.	.	.	.	1970	.	.	.	.	.	.	.	.	.	1980	.	.	.	.	.	.	.	.	.	1990	.	.	.	.	.	.	.	.	.	2000	.	.	.	.	.	.	.	.	.	2010
Sequence	T	V	S	F	E	E	H	I	K	L	E	H	N	M	W	N	Y	L	Y	F	I	V	L	V	R	V	K	N	K	T	D	Y	T	G	P	E	S	Y	V	A	Q	M	I	c	7	t	3	u	A	_
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	S	S						T	T	T	T	S													T	T	S		T	T	T														T	T				S