PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.0

Fold library entry viewer: c7pguF_

Fold library id	PDB Header	Molecule	Title
c7pguF_	3.30	PDB header: signaling protein	Chain: F: PDB Molecule: neurofibromin;

Links to external resources
Added to library: Sat Nov 20 08:47:43 2021

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence H R P V E W V Q A V V S R F D E Q L P I K T G Q Q N T H T K V S T E H N K E C L I N I S K Y K F S L V I S G L T T I L K N V N N M R I F G E

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T S T T S
S T T T T T T T T
S
S

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence A A E K N L Y L S Q L I I L D T L E K C L A G Q P K D T M R L D E T M L V K Q L L P E I C H F L H T C R E G N Q H A A E L R N S A S G V L F

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T S
S S
T T S
S
S S

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence S L S C N N F N A V F S R I S T R L Q E L T V C S E D N V D V H D I E L L Q Y I N V D C A K L K R L L K E T A F K F K A L K K V A Q L A V I

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T S S
S S
T T G G G G G T S
T T T

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240 . . . . . . . . . 250 . . . . . . . . . 260 . . . . . . . . . 270 . . . . . . . . . 280

Sequence N S L E K A F W N W V E N Y P D E F T K L Y Q I P Q T D M A E C A E K L F D L V D G F A E S T K R K A A V W P L Q I I L L I L C P E I I Q D

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S
S T T S

. . . . . . . . . 290 . . . . . . . . . 300 . . . . . . . . . 310 . . . . . . . . . 320 . . . . . . . . . 330 . . . . . . . . . 340 . . . . . . . . . 350

Sequence I S K D V V D E N N M N K K L F L D S L R K A L A G H G G S R Q L T E S A A I A C V K L C K A S T Y I N W E D N S V I F L L V Q S M V V D L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S
S S T T T
S S
T T S
S S S

. . . . . . . . . 360 . . . . . . . . . 370 . . . . . . . . . 380 . . . . . . . . . 390 . . . . . . . . . 400 . . . . . . . . . 410 . . . . . . . . . 420

Sequence K N L L F N P S K P F S R G S Q P A D V D L M I D C L V S C F R I S P H N N Q H F K I C L A Q N S P S T F H Y V L V N S L H R I I T N S A L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S
T T S
S S S S S
S S S
S S S S S S

. . . . . . . . . 430 . . . . . . . . . 440 . . . . . . . . . 450 . . . . . . . . . 460 . . . . . . . . . 470 . . . . . . . . . 480 . . . . . . . . . 490

Sequence D W W P K I D A V Y C H S V E L R N M F G E T L H K A V Q G C G T D L E T R S Y K Y L L L S M V K L I H A D P K L L L C N P R K Q G P E T Q

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S S S
G G G G G G G
T T
G G G T S S S
S S S

. . . . . . . . . 500 . . . . . . . . . 510 . . . . . . . . . 520 . . . . . . . . . 530 . . . . . . . . . 540 . . . . . . . . . 550 . . . . . . . . . 560

Sequence G S T A E L I T G L V Q L V P Q S H M P E I A Q E A M E A L L V L H Q L D S I D L W N P D A P V E T F W E I S S Q M L F Y I C K K L T S H Q

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T T T
S S
T T S T T T S T T S
T T S T T S

. . . . . . . . . 570 . . . . . . . . . 580 . . . . . . . . . 590 . . . . . . . . . 600 . . . . . . . . . 610 . . . . . . . . . 620 . . . . . . . . . 630

Sequence M L S S T E I L K W L R E I L I C R N K F L L K N K Q A D R S S G T P P I C R Q A Q T K L E V A L Y M F L W N P D T E A V L V A M S C F R H

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T
T T T T T
S

. . . . . . . . . 640 . . . . . . . . . 650 . . . . . . . . . 660 . . . . . . . . . 670 . . . . . . . . . 680 . . . . . . . . . 690 . . . . . . . . . 700

Sequence L C E E A D I R C G V D E V S V H N L L P N Y N T F M E F A S V S N M M S T G R A A L Q K R V M A L L R R I E H P T A G N T E A W E D T H A

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T T T S T T S S
T T
S

. . . . . . . . . 710 . . . . . . . . . 720 . . . . . . . . . 730 . . . . . . . . . 740 . . . . . . . . . 750 . . . . . . . . . 760 . . . . . . . . . 770

Sequence K W E Q A T K L I L N Y P T D S L Q E W I N M T G F L C A L G G V C L Q A D T P V S K F M D R L L S L M V C N H E K V G L Q I R T N V K D L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T
T
S T T
T T
T T T

. . . . . . . . . 780 . . . . . . . . . 790 . . . . . . . . . 800 . . . . . . . . . 810 . . . . . . . . . 820 . . . . . . . . . 830 . . . . . . . . . 840

Sequence V G L E L S P A L Y P M L F N K L K N T I S K F F D S Q G Q V L L T D T N T Q F V E Q T I A I M K N L L D N H T E G S S E H L G Q A S I E T

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T
G G G G G G T T T
S S S S
T T
T S S

. . . . . . . . . 850 . . . . . . . . . 860 . . . . . . . . . 870 . . . . . . . . . 880 . . . . . . . . . 890 . . . . . . . . . 900 . . . . . . . . . 910

Sequence M M L N L V R Y V R V L G N M V H A I Q I K T K L C Q L V E V M M A R R D D L S F C Q E M K F R N K M V E Y L T D W V M G T S N Q A A D D D

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T S
S S T T T T T T S
S S T T S
S S T
S

. . . . . . . . . 920 . . . . . . . . . 930 . . . . . . . . . 940 . . . . . . . . . 950 . . . . . . . . . 960 . . . . . . . . . 970 . . . . . . . . . 980

Sequence V K C L T R D L D Q A S M E A V V S L L A G L P L Q P E E G D G V E L M E A K S Q L F L K Y F T L F M N L L N D C S E V E M S R R L A S L R

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) G G G S T T
S
S S S
T T S S
T T

. . . . . . . . . 990 . . . . . . . . . 1000 . . . . . . . . . 1010 . . . . . . . . . 1020 . . . . . . . . . 1030 . . . . . . . . . 1040 . . . . . . . . . 1050

Sequence H C T V L A M S N L L N A N V D S G L M H S I G L G Y H K D L Q T R A T F M E V L T K I L Q Q G T E F D T L A E T V L A D R F E R L V E L V

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T
S T T T G G G G G
S
S
S S
T T
T T T T S

. . . . . . . . . 1060 . . . . . . . . . 1070 . . . . . . . . . 1080 . . . . . . . . . 1090 . . . . . . . . . 1100 . . . . . . . . . 1110 . . . . . . . . . 1120

Sequence T M M G D Q G E L P I A M A L A N V V P C S Q W D E L A R V L V T L F D S R H L L Y Q L L W N M F S K E V E L A D S M Q T L F R G N S L A S

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T
T T T
S
G G G T T
T T G G G G G G S S S

. . . . . . . . . 1130 . . . . . . . . . 1140 . . . . . . . . . 1150 . . . . . . . . . 1160 . . . . . . . . . 1170 . . . . . . . . . 1180 . . . . . . . . . 1190

Sequence K I M T F C F K V Y G A T Y L Q K L L D P L L R I V I T S S D W Q H V S F E V D P T R L E P S E S L E E N Q R N L L Q M T E K F F H A I I S

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S
G G G S S
T T T
S S

. . . . . . . . . 1200 . . . . . . . . . 1210 . . . . . . . . . 1220 . . . . . . . . . 1230 . . . . . . . . . 1240 . . . . . . . . . 1250 . . . . . . . . . 1260

Sequence S S S E F P P Q L R S V C H C L Y Q A T C H S L L N K P Q N S I G A V G S A M F L R F I N P A I V S P Y E A G I L D K K P P P R I E R G L K

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T S T T S
T T
S G G G T S
S S

. . . . . . . . . 1270 . . . . . . . . . 1280 . . . . . . . . . 1290 . . . . . . . . . 1300 . . . . . . . . . 1310 . . . . . . . . . 1320 . . . . . . . . . 1330

Sequence L M S K I L Q S I A N H V L F T K E E H M R P F N D F V K S N F D A A R R F F L D I A S D C P T S D A V N H S L S F I S D G N V L A L H R L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T
S
T T T G G G T T S
S S
S S S

. . . . . . . . . 1340 . . . . . . . . . 1350 . . . . . . . . . 1360 . . . . . . . . . 1370 . . . . . . . . . 1380 . . . . . . . . . 1390 . . . . . . . . . 1400

Sequence L W N N Q E K I G Q Y L S S N R D H K A V G R R P F D K M A T L L A Y L G P P E H K P V A D T H W S S L N L T S S K F E E F M T R H Q V H E

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T S
S S
T T S S
S
S S
S S
S
T T

. . . . . . . . . 1410 . . . . . . . . . 1420 . . . . . . . . . 1430 . . . . . . . . . 1440 . . . . . . . . . 1450 . . . . . . . . . 1460 . . . . . . . . . 1470

Sequence K E E F K A L K T L S I F Y Q A G T S K A G N P I F Y Y V A R R F K T G Q I N G D L L I Y H V L L T L K P Y Y A K P Y E I V V D L T H T G P

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S S S S S T S
T T S
G G G
T T T S
T T T T T T T S
T T
G

. . . . . . . . . 1480 . . . . . . . . . 1490 . . . . . . . . . 1500 . . . . . . . . . 1510 . . . . . . . . . 1520 . . . . . . . . . 1530 . . . . . . . . . 1540

Sequence S N R F K T D F L S K W F V V F P G F A Y D N V S A V Y I Y N C N S W V R E Y T K Y H E R L L T G L K G S K R L V F I D C P G K L A E H I E

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) G G
G G G G S S S
T S
T T T G G G G T T T
S S
S S S

. . . . . . . . . 1550 . . . . . . . . . 1560 . . . . . . . . . 1570 . . . . . . . . . 1580 . . . . . . . . . 1590 . . . . . . . . . 1600 . . . . . . . . . 1610

Sequence H E Q Q K L P A A T L A L E E D L K V F H N A L K L A H K D T K V S I K V G S T A V Q V T S A E R T K V L G Q S V F L N D I Y Y A S E I E E

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T T
T T S S
T T
S S S
S S S S
T T
G G G

. . . . . . . . . 1620 . . . . . . . . . 1630 . . . . . . . . . 1640 . . . . . . . . . 1650 . . . . . . . . . 1660 . . . . . . . . . 1670 . . . . . . . . . 1680

Sequence I C L V D E N Q F T L T I A N Q G T P L T F M H Q E C E A I V Q S I I H I R T R W E L S Q P D S I P Q H T K I R P K D V P G T L L N I A L L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S
S S T T S
S
T T
S
G G G

. . . . . . . . . 1690 . . . . . . . . . 1700 . . . . . . . . . 1710 . . . . . . . . . 1720 . . . . . . . . . 1730 . . . . . . . . . 1740 . . . . . . . . . 1750

Sequence N L G S S D P S L R S A A Y N L L C A L T C T F N L K I E G Q L L E T S G L C I P A N N T L F I V S I S K T L A A N E P H L T L E F L E E C

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T
S
S
S S
S S
S
T
G G G

. . . . . . . . . 1760 . . . . . . . . . 1770 . . . . . . . . . 1780 . . . . . . . . . 1790 . . . . . . . . . 1800 . . . . . . . . . 1810 . . . . . . . . . 1820

Sequence I S G F S K S S I E L K H L C L E Y M T P W L S N L V R F C K H N D D A K R Q R V T A I L D K L I T M T I N E K Q M Y P S I Q A K I W G S L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T S
G G G G G G G T S T T S S S
S S

. . . . . . . . . 1830 . . . . . . . . . 1840 . . . . . . . . . 1850 . . . . . . . . . 1860 . . . . . . . . . 1870 . . . . . . . . . 1880 . . . . . . . . . 1890

Sequence G Q I T D L L D V V L D S F I K T S A T G G L G S I K A E V M A D T A V A L A S G N V K L V S S K V I G R M C K I I D K T C L S P T P T L E

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T
G G G
T T
G G G S S
S S S T

. . . . . . . . . 1900 . . . . . . . . . 1910 . . . . . . . . . 1920 . . . . . . . . . 1930 . . . . . . . . . 1940 . . . . . . . . . 1950 . . . . . . . . . 1960

Sequence Q H L M W D D I A I L A R Y M L M L S F N N S L D V A A H L P Y L F H V V T F L V A T G P L S L R A S T H G L V I N I I H S L C T C S Q L H

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T S T T G G G T T
T T
S
T
S S S

. . . . . . . . . 1970 . . . . . . . . . 1980 . . . . . . . . . 1990 . . . . . . . . . 2000 . . . . . . . . . 2010 . . . . . . . . . 2020 . . . . . . . . . 2030

Sequence F S E E T K Q V L R L S L T E F S L P K F Y L L F G I S K V K S A A V I A F R S S Y R D R S F S P G S Y E R E T F A L T S L E T V T E A L L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T S T T
T T
S
T T T T T

. . . . . . . . . 2040 . . . . . . . . . 2050 . . . . . . . . . 2060 . . . . . . . . . 2070 . . . . . . . . . 2080 . . . . . . . . . 2090 . . . . . . . . . 2100

Sequence E I M E A C M R D I P T C K W L D Q W T E L A Q R F A F Q Y N P S L Q P R A L V V F G C I S K R V S H G Q I K Q I I R I L S K A L E S C L K

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T S T T
T S
T T T

. . . . . . . . . 2110 . . . . . . . . . 2120 . . . . . . . . . 2130 . . . . . . . . . 2140 . . . . . . . . . 2150 . . . . . . . . . 2160 . . . . . . . . . 2170

Sequence G P D T Y N S Q V L I E A T V I A L T K L Q P L L N K D S P L H K A L F W V A V A V L Q L D E V N L Y S A G T A L L E Q N L H T L D S L R I

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S S
G G G S
T T
T T S
T T S

. . . . . . . . . 2180 . . . . . . . . . 2190 . . . . . . . . . 2200 . . . . . . . . . 2210 . . . . . . . . . 2220 . . . . . . . . . 2230 . . . . . . . . . 2240

Sequence F N D K S P E E V F M A I R N P L E W H C K Q M D H F V G L N F N S N F N F A L V G H L L K G Y R H P S P A I V A R T V R I L H T L L T L V

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S S S S
T G G G T
T T T
S G G G G
S S

. . . . . . . . . 2250 . . . . . . . . . 2260 . . . . . . . . . 2270 . . . . . . . . . 2280 . . . . . . . . . 2290 . . . . . . . . . 2300 . . . . . . . . . 2310

Sequence N K H R N C D K F E V N T Q S V A Y L A A L L T V S E E V R S R C S L K H R S N V L L D E E V L T D P K I Q A L L L T V L A T L V K Y T T D

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T
T T T
S T T T T T T
B
S
B
S S
T T T
S

. . . . . . . . . 2320 . . . . . . . . . 2330 . . . . . . . . . 2340 . . . . . . . . . 2350 . . . . . . . . . 2360 . . . . . . . . . 2370 . . . . . . . . . 2380

Sequence E F D Q R I L Y E Y L A E A S V V F P K V F P V V H N L L D S K I N T L L S L C Q D P N L L N P I H G I V Q S V V Y H E E S P P Q Y Q T S Y

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T T G G G G
T T S
S S
T T

. . . . . . . . . 2390 . . . . . . . . . 2400 . . . . . . . . . 2410 . . . . . . . . . 2420 . . .

Sequence L Q S F G F N G L W R F A G P F S K Q T Q I P D Y A E L I V K F L D A L I D T Y L P G

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T T T S T S
S S
S

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Please cite: The Phyre2 web portal for protein modeling, prediction and analysis

Kelley LA et al. Nature Protocols 10, 845-858 (2015) [paper] [Citation link]

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	H	R	P	V	E	W	V	Q	A	V	V	S	R	F	D	E	Q	L	P	I	K	T	G	Q	Q	N	T	H	T	K	V	S	T	E	H	N	K	E	C	L	I	N	I	S	K	Y	K	F	S	L	V	I	S	G	L	T	T	I	L	K	N	V	N	N	M	R	I	F	G	E
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																T	T	S	T	T	S				S	T	T	T	T	T														T	T	T																		S					S
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	A	A	E	K	N	L	Y	L	S	Q	L	I	I	L	D	T	L	E	K	C	L	A	G	Q	P	K	D	T	M	R	L	D	E	T	M	L	V	K	Q	L	L	P	E	I	C	H	F	L	H	T	C	R	E	G	N	Q	H	A	A	E	L	R	N	S	A	S	G	V	L	F
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																							T	S		S	S												T	T									S				S		S	S
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	S	L	S	C	N	N	F	N	A	V	F	S	R	I	S	T	R	L	Q	E	L	T	V	C	S	E	D	N	V	D	V	H	D	I	E	L	L	Q	Y	I	N	V	D	C	A	K	L	K	R	L	L	K	E	T	A	F	K	F	K	A	L	K	K	V	A	Q	L	A	V	I
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)		T	T	S	S																				S	S						T	T	G	G	G	G	G	T	S																		T	T	T
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280
Sequence	N	S	L	E	K	A	F	W	N	W	V	E	N	Y	P	D	E	F	T	K	L	Y	Q	I	P	Q	T	D	M	A	E	C	A	E	K	L	F	D	L	V	D	G	F	A	E	S	T	K	R	K	A	A	V	W	P	L	Q	I	I	L	L	I	L	C	P	E	I	I	Q	D
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																								S																						S																T	T	S
	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350
Sequence	I	S	K	D	V	V	D	E	N	N	M	N	K	K	L	F	L	D	S	L	R	K	A	L	A	G	H	G	G	S	R	Q	L	T	E	S	A	A	I	A	C	V	K	L	C	K	A	S	T	Y	I	N	W	E	D	N	S	V	I	F	L	L	V	Q	S	M	V	V	D	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			S				S	S	T	T																T		S	S																				T	T	S		S	S	S
	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence	K	N	L	L	F	N	P	S	K	P	F	S	R	G	S	Q	P	A	D	V	D	L	M	I	D	C	L	V	S	C	F	R	I	S	P	H	N	N	Q	H	F	K	I	C	L	A	Q	N	S	P	S	T	F	H	Y	V	L	V	N	S	L	H	R	I	I	T	N	S	A	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)					S		T	T	S					S	S	S	S	S																S	S	S			S	S						S	S	S	S
	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490
Sequence	D	W	W	P	K	I	D	A	V	Y	C	H	S	V	E	L	R	N	M	F	G	E	T	L	H	K	A	V	Q	G	C	G	T	D	L	E	T	R	S	Y	K	Y	L	L	L	S	M	V	K	L	I	H	A	D	P	K	L	L	L	C	N	P	R	K	Q	G	P	E	T	Q
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	S	S	S			G	G	G	G	G	G	G																																								T	T		G	G	G	T	S	S	S						S	S	S
	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560
Sequence	G	S	T	A	E	L	I	T	G	L	V	Q	L	V	P	Q	S	H	M	P	E	I	A	Q	E	A	M	E	A	L	L	V	L	H	Q	L	D	S	I	D	L	W	N	P	D	A	P	V	E	T	F	W	E	I	S	S	Q	M	L	F	Y	I	C	K	K	L	T	S	H	Q
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)												T	T	T	T		S	S															T	T	S	T	T	T	S	T	T	S		T	T	S																					T	T	S
	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630
Sequence	M	L	S	S	T	E	I	L	K	W	L	R	E	I	L	I	C	R	N	K	F	L	L	K	N	K	Q	A	D	R	S	S	G	T	P	P	I	C	R	Q	A	Q	T	K	L	E	V	A	L	Y	M	F	L	W	N	P	D	T	E	A	V	L	V	A	M	S	C	F	R	H
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)		T	T																																										T						T	T	T	T		S
	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.	.	660	.	.	.	.	.	.	.	.	.	670	.	.	.	.	.	.	.	.	.	680	.	.	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700
Sequence	L	C	E	E	A	D	I	R	C	G	V	D	E	V	S	V	H	N	L	L	P	N	Y	N	T	F	M	E	F	A	S	V	S	N	M	M	S	T	G	R	A	A	L	Q	K	R	V	M	A	L	L	R	R	I	E	H	P	T	A	G	N	T	E	A	W	E	D	T	H	A
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)												T	T	T	T					S	T	T												S	S																	T	T			S
	.	.	.	.	.	.	.	.	.	710	.	.	.	.	.	.	.	.	.	720	.	.	.	.	.	.	.	.	.	730	.	.	.	.	.	.	.	.	.	740	.	.	.	.	.	.	.	.	.	750	.	.	.	.	.	.	.	.	.	760	.	.	.	.	.	.	.	.	.	770
Sequence	K	W	E	Q	A	T	K	L	I	L	N	Y	P	T	D	S	L	Q	E	W	I	N	M	T	G	F	L	C	A	L	G	G	V	C	L	Q	A	D	T	P	V	S	K	F	M	D	R	L	L	S	L	M	V	C	N	H	E	K	V	G	L	Q	I	R	T	N	V	K	D	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)											T																			T		S	T	T																		T	T				T	T	T
	.	.	.	.	.	.	.	.	.	780	.	.	.	.	.	.	.	.	.	790	.	.	.	.	.	.	.	.	.	800	.	.	.	.	.	.	.	.	.	810	.	.	.	.	.	.	.	.	.	820	.	.	.	.	.	.	.	.	.	830	.	.	.	.	.	.	.	.	.	840
Sequence	V	G	L	E	L	S	P	A	L	Y	P	M	L	F	N	K	L	K	N	T	I	S	K	F	F	D	S	Q	G	Q	V	L	L	T	D	T	N	T	Q	F	V	E	Q	T	I	A	I	M	K	N	L	L	D	N	H	T	E	G	S	S	E	H	L	G	Q	A	S	I	E	T
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)				T			G	G	G													G	G	G			T	T	T						S	S																	S	S			T	T						T	S	S
	.	.	.	.	.	.	.	.	.	850	.	.	.	.	.	.	.	.	.	860	.	.	.	.	.	.	.	.	.	870	.	.	.	.	.	.	.	.	.	880	.	.	.	.	.	.	.	.	.	890	.	.	.	.	.	.	.	.	.	900	.	.	.	.	.	.	.	.	.	910
Sequence	M	M	L	N	L	V	R	Y	V	R	V	L	G	N	M	V	H	A	I	Q	I	K	T	K	L	C	Q	L	V	E	V	M	M	A	R	R	D	D	L	S	F	C	Q	E	M	K	F	R	N	K	M	V	E	Y	L	T	D	W	V	M	G	T	S	N	Q	A	A	D	D	D
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)										T	T	S		S	S	T	T																		T	T	T	T	S			S	S													T	T	S			S	S						T		S
	.	.	.	.	.	.	.	.	.	920	.	.	.	.	.	.	.	.	.	930	.	.	.	.	.	.	.	.	.	940	.	.	.	.	.	.	.	.	.	950	.	.	.	.	.	.	.	.	.	960	.	.	.	.	.	.	.	.	.	970	.	.	.	.	.	.	.	.	.	980
Sequence	V	K	C	L	T	R	D	L	D	Q	A	S	M	E	A	V	V	S	L	L	A	G	L	P	L	Q	P	E	E	G	D	G	V	E	L	M	E	A	K	S	Q	L	F	L	K	Y	F	T	L	F	M	N	L	L	N	D	C	S	E	V	E	M	S	R	R	L	A	S	L	R
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	G	G	G																	S	T	T							S		S	S	S																							T	T	S	S				T	T
	.	.	.	.	.	.	.	.	.	990	.	.	.	.	.	.	.	.	.	1000	.	.	.	.	.	.	.	.	.	1010	.	.	.	.	.	.	.	.	.	1020	.	.	.	.	.	.	.	.	.	1030	.	.	.	.	.	.	.	.	.	1040	.	.	.	.	.	.	.	.	.	1050
Sequence	H	C	T	V	L	A	M	S	N	L	L	N	A	N	V	D	S	G	L	M	H	S	I	G	L	G	Y	H	K	D	L	Q	T	R	A	T	F	M	E	V	L	T	K	I	L	Q	Q	G	T	E	F	D	T	L	A	E	T	V	L	A	D	R	F	E	R	L	V	E	L	V
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)													T						S	T	T	T	G	G	G	G	G		S																		S		S	S		T	T						T	T	T	T	S
	.	.	.	.	.	.	.	.	.	1060	.	.	.	.	.	.	.	.	.	1070	.	.	.	.	.	.	.	.	.	1080	.	.	.	.	.	.	.	.	.	1090	.	.	.	.	.	.	.	.	.	1100	.	.	.	.	.	.	.	.	.	1110	.	.	.	.	.	.	.	.	.	1120
Sequence	T	M	M	G	D	Q	G	E	L	P	I	A	M	A	L	A	N	V	V	P	C	S	Q	W	D	E	L	A	R	V	L	V	T	L	F	D	S	R	H	L	L	Y	Q	L	L	W	N	M	F	S	K	E	V	E	L	A	D	S	M	Q	T	L	F	R	G	N	S	L	A	S
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T				T	T	T												S		G	G	G															T	T																		T	T	G	G	G	G	G	G	S	S	S
	.	.	.	.	.	.	.	.	.	1130	.	.	.	.	.	.	.	.	.	1140	.	.	.	.	.	.	.	.	.	1150	.	.	.	.	.	.	.	.	.	1160	.	.	.	.	.	.	.	.	.	1170	.	.	.	.	.	.	.	.	.	1180	.	.	.	.	.	.	.	.	.	1190
Sequence	K	I	M	T	F	C	F	K	V	Y	G	A	T	Y	L	Q	K	L	L	D	P	L	L	R	I	V	I	T	S	S	D	W	Q	H	V	S	F	E	V	D	P	T	R	L	E	P	S	E	S	L	E	E	N	Q	R	N	L	L	Q	M	T	E	K	F	F	H	A	I	I	S
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)											S																			G	G	G	S	S							T	T	T			S	S
	.	.	.	.	.	.	.	.	.	1200	.	.	.	.	.	.	.	.	.	1210	.	.	.	.	.	.	.	.	.	1220	.	.	.	.	.	.	.	.	.	1230	.	.	.	.	.	.	.	.	.	1240	.	.	.	.	.	.	.	.	.	1250	.	.	.	.	.	.	.	.	.	1260
Sequence	S	S	S	E	F	P	P	Q	L	R	S	V	C	H	C	L	Y	Q	A	T	C	H	S	L	L	N	K	P	Q	N	S	I	G	A	V	G	S	A	M	F	L	R	F	I	N	P	A	I	V	S	P	Y	E	A	G	I	L	D	K	K	P	P	P	R	I	E	R	G	L	K
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T	S	T	T	S																																						T	T							S	G	G	G	T	S		S	S
	.	.	.	.	.	.	.	.	.	1270	.	.	.	.	.	.	.	.	.	1280	.	.	.	.	.	.	.	.	.	1290	.	.	.	.	.	.	.	.	.	1300	.	.	.	.	.	.	.	.	.	1310	.	.	.	.	.	.	.	.	.	1320	.	.	.	.	.	.	.	.	.	1330
Sequence	L	M	S	K	I	L	Q	S	I	A	N	H	V	L	F	T	K	E	E	H	M	R	P	F	N	D	F	V	K	S	N	F	D	A	A	R	R	F	F	L	D	I	A	S	D	C	P	T	S	D	A	V	N	H	S	L	S	F	I	S	D	G	N	V	L	A	L	H	R	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)												T					S		T	T	T	G	G	G							T													T	S		S	S		S	S	S
	.	.	.	.	.	.	.	.	.	1340	.	.	.	.	.	.	.	.	.	1350	.	.	.	.	.	.	.	.	.	1360	.	.	.	.	.	.	.	.	.	1370	.	.	.	.	.	.	.	.	.	1380	.	.	.	.	.	.	.	.	.	1390	.	.	.	.	.	.	.	.	.	1400
Sequence	L	W	N	N	Q	E	K	I	G	Q	Y	L	S	S	N	R	D	H	K	A	V	G	R	R	P	F	D	K	M	A	T	L	L	A	Y	L	G	P	P	E	H	K	P	V	A	D	T	H	W	S	S	L	N	L	T	S	S	K	F	E	E	F	M	T	R	H	Q	V	H	E
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)				T											S			S	S		T	T	S	S														S								S	S					S	S													S			T	T
	.	.	.	.	.	.	.	.	.	1410	.	.	.	.	.	.	.	.	.	1420	.	.	.	.	.	.	.	.	.	1430	.	.	.	.	.	.	.	.	.	1440	.	.	.	.	.	.	.	.	.	1450	.	.	.	.	.	.	.	.	.	1460	.	.	.	.	.	.	.	.	.	1470
Sequence	K	E	E	F	K	A	L	K	T	L	S	I	F	Y	Q	A	G	T	S	K	A	G	N	P	I	F	Y	Y	V	A	R	R	F	K	T	G	Q	I	N	G	D	L	L	I	Y	H	V	L	L	T	L	K	P	Y	Y	A	K	P	Y	E	I	V	V	D	L	T	H	T	G	P
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	S	S	S	S	S						T	S								T	T	S								G	G	G			T	T	T	S												T	T	T	T	T	T	T	S									T	T			G
	.	.	.	.	.	.	.	.	.	1480	.	.	.	.	.	.	.	.	.	1490	.	.	.	.	.	.	.	.	.	1500	.	.	.	.	.	.	.	.	.	1510	.	.	.	.	.	.	.	.	.	1520	.	.	.	.	.	.	.	.	.	1530	.	.	.	.	.	.	.	.	.	1540
Sequence	S	N	R	F	K	T	D	F	L	S	K	W	F	V	V	F	P	G	F	A	Y	D	N	V	S	A	V	Y	I	Y	N	C	N	S	W	V	R	E	Y	T	K	Y	H	E	R	L	L	T	G	L	K	G	S	K	R	L	V	F	I	D	C	P	G	K	L	A	E	H	I	E
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	G	G								G	G	G	G	S	S	S							T								S												T	T	T	G	G	G	G	T	T	T		S	S					S	S								S
	.	.	.	.	.	.	.	.	.	1550	.	.	.	.	.	.	.	.	.	1560	.	.	.	.	.	.	.	.	.	1570	.	.	.	.	.	.	.	.	.	1580	.	.	.	.	.	.	.	.	.	1590	.	.	.	.	.	.	.	.	.	1600	.	.	.	.	.	.	.	.	.	1610
Sequence	H	E	Q	Q	K	L	P	A	A	T	L	A	L	E	E	D	L	K	V	F	H	N	A	L	K	L	A	H	K	D	T	K	V	S	I	K	V	G	S	T	A	V	Q	V	T	S	A	E	R	T	K	V	L	G	Q	S	V	F	L	N	D	I	Y	Y	A	S	E	I	E	E
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T	T	T										T	T	S	S					T	T					S	S	S										S	S							S	S					T	T											G	G	G
	.	.	.	.	.	.	.	.	.	1620	.	.	.	.	.	.	.	.	.	1630	.	.	.	.	.	.	.	.	.	1640	.	.	.	.	.	.	.	.	.	1650	.	.	.	.	.	.	.	.	.	1660	.	.	.	.	.	.	.	.	.	1670	.	.	.	.	.	.	.	.	.	1680
Sequence	I	C	L	V	D	E	N	Q	F	T	L	T	I	A	N	Q	G	T	P	L	T	F	M	H	Q	E	C	E	A	I	V	Q	S	I	I	H	I	R	T	R	W	E	L	S	Q	P	D	S	I	P	Q	H	T	K	I	R	P	K	D	V	P	G	T	L	L	N	I	A	L	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)				S		S	S							T	T	S		S							T	T																										S					G	G	G
	.	.	.	.	.	.	.	.	.	1690	.	.	.	.	.	.	.	.	.	1700	.	.	.	.	.	.	.	.	.	1710	.	.	.	.	.	.	.	.	.	1720	.	.	.	.	.	.	.	.	.	1730	.	.	.	.	.	.	.	.	.	1740	.	.	.	.	.	.	.	.	.	1750
Sequence	N	L	G	S	S	D	P	S	L	R	S	A	A	Y	N	L	L	C	A	L	T	C	T	F	N	L	K	I	E	G	Q	L	L	E	T	S	G	L	C	I	P	A	N	N	T	L	F	I	V	S	I	S	K	T	L	A	A	N	E	P	H	L	T	L	E	F	L	E	E	C
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)		T	T		S																			S					S	S						S	S					S																T		G	G	G
	.	.	.	.	.	.	.	.	.	1760	.	.	.	.	.	.	.	.	.	1770	.	.	.	.	.	.	.	.	.	1780	.	.	.	.	.	.	.	.	.	1790	.	.	.	.	.	.	.	.	.	1800	.	.	.	.	.	.	.	.	.	1810	.	.	.	.	.	.	.	.	.	1820
Sequence	I	S	G	F	S	K	S	S	I	E	L	K	H	L	C	L	E	Y	M	T	P	W	L	S	N	L	V	R	F	C	K	H	N	D	D	A	K	R	Q	R	V	T	A	I	L	D	K	L	I	T	M	T	I	N	E	K	Q	M	Y	P	S	I	Q	A	K	I	W	G	S	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)					T	T	S													G	G	G	G	G	G	G					T	S	T	T	S	S	S																				S	S
	.	.	.	.	.	.	.	.	.	1830	.	.	.	.	.	.	.	.	.	1840	.	.	.	.	.	.	.	.	.	1850	.	.	.	.	.	.	.	.	.	1860	.	.	.	.	.	.	.	.	.	1870	.	.	.	.	.	.	.	.	.	1880	.	.	.	.	.	.	.	.	.	1890
Sequence	G	Q	I	T	D	L	L	D	V	V	L	D	S	F	I	K	T	S	A	T	G	G	L	G	S	I	K	A	E	V	M	A	D	T	A	V	A	L	A	S	G	N	V	K	L	V	S	S	K	V	I	G	R	M	C	K	I	I	D	K	T	C	L	S	P	T	P	T	L	E
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T	T		G	G	G																	T	T																																				G	G	G	S	S			S	S	S	T
	.	.	.	.	.	.	.	.	.	1900	.	.	.	.	.	.	.	.	.	1910	.	.	.	.	.	.	.	.	.	1920	.	.	.	.	.	.	.	.	.	1930	.	.	.	.	.	.	.	.	.	1940	.	.	.	.	.	.	.	.	.	1950	.	.	.	.	.	.	.	.	.	1960
Sequence	Q	H	L	M	W	D	D	I	A	I	L	A	R	Y	M	L	M	L	S	F	N	N	S	L	D	V	A	A	H	L	P	Y	L	F	H	V	V	T	F	L	V	A	T	G	P	L	S	L	R	A	S	T	H	G	L	V	I	N	I	I	H	S	L	C	T	C	S	Q	L	H
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T	S	T	T																G	G	G	T	T																	T	T		S																					T		S	S	S
	.	.	.	.	.	.	.	.	.	1970	.	.	.	.	.	.	.	.	.	1980	.	.	.	.	.	.	.	.	.	1990	.	.	.	.	.	.	.	.	.	2000	.	.	.	.	.	.	.	.	.	2010	.	.	.	.	.	.	.	.	.	2020	.	.	.	.	.	.	.	.	.	2030
Sequence	F	S	E	E	T	K	Q	V	L	R	L	S	L	T	E	F	S	L	P	K	F	Y	L	L	F	G	I	S	K	V	K	S	A	A	V	I	A	F	R	S	S	Y	R	D	R	S	F	S	P	G	S	Y	E	R	E	T	F	A	L	T	S	L	E	T	V	T	E	A	L	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																T	T	S							T	T		T	T		S									T	T	T	T	T
	.	.	.	.	.	.	.	.	.	2040	.	.	.	.	.	.	.	.	.	2050	.	.	.	.	.	.	.	.	.	2060	.	.	.	.	.	.	.	.	.	2070	.	.	.	.	.	.	.	.	.	2080	.	.	.	.	.	.	.	.	.	2090	.	.	.	.	.	.	.	.	.	2100
Sequence	E	I	M	E	A	C	M	R	D	I	P	T	C	K	W	L	D	Q	W	T	E	L	A	Q	R	F	A	F	Q	Y	N	P	S	L	Q	P	R	A	L	V	V	F	G	C	I	S	K	R	V	S	H	G	Q	I	K	Q	I	I	R	I	L	S	K	A	L	E	S	C	L	K
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)									T	S	T	T																T	S			T	T	T
	.	.	.	.	.	.	.	.	.	2110	.	.	.	.	.	.	.	.	.	2120	.	.	.	.	.	.	.	.	.	2130	.	.	.	.	.	.	.	.	.	2140	.	.	.	.	.	.	.	.	.	2150	.	.	.	.	.	.	.	.	.	2160	.	.	.	.	.	.	.	.	.	2170
Sequence	G	P	D	T	Y	N	S	Q	V	L	I	E	A	T	V	I	A	L	T	K	L	Q	P	L	L	N	K	D	S	P	L	H	K	A	L	F	W	V	A	V	A	V	L	Q	L	D	E	V	N	L	Y	S	A	G	T	A	L	L	E	Q	N	L	H	T	L	D	S	L	R	I
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	S	S																				G	G	G	S		T	T		T														T	S																							T	T	S
	.	.	.	.	.	.	.	.	.	2180	.	.	.	.	.	.	.	.	.	2190	.	.	.	.	.	.	.	.	.	2200	.	.	.	.	.	.	.	.	.	2210	.	.	.	.	.	.	.	.	.	2220	.	.	.	.	.	.	.	.	.	2230	.	.	.	.	.	.	.	.	.	2240
Sequence	F	N	D	K	S	P	E	E	V	F	M	A	I	R	N	P	L	E	W	H	C	K	Q	M	D	H	F	V	G	L	N	F	N	S	N	F	N	F	A	L	V	G	H	L	L	K	G	Y	R	H	P	S	P	A	I	V	A	R	T	V	R	I	L	H	T	L	L	T	L	V
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	S	S	S	S										T	G	G	G												T			T	T	T											S	G	G	G	G		S	S
	.	.	.	.	.	.	.	.	.	2250	.	.	.	.	.	.	.	.	.	2260	.	.	.	.	.	.	.	.	.	2270	.	.	.	.	.	.	.	.	.	2280	.	.	.	.	.	.	.	.	.	2290	.	.	.	.	.	.	.	.	.	2300	.	.	.	.	.	.	.	.	.	2310
Sequence	N	K	H	R	N	C	D	K	F	E	V	N	T	Q	S	V	A	Y	L	A	A	L	L	T	V	S	E	E	V	R	S	R	C	S	L	K	H	R	S	N	V	L	L	D	E	E	V	L	T	D	P	K	I	Q	A	L	L	L	T	V	L	A	T	L	V	K	Y	T	T	D
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)					T		T	T	T			S	T	T	T								T	T	T								B			S				B		S	S		T	T	T			S
	.	.	.	.	.	.	.	.	.	2320	.	.	.	.	.	.	.	.	.	2330	.	.	.	.	.	.	.	.	.	2340	.	.	.	.	.	.	.	.	.	2350	.	.	.	.	.	.	.	.	.	2360	.	.	.	.	.	.	.	.	.	2370	.	.	.	.	.	.	.	.	.	2380
Sequence	E	F	D	Q	R	I	L	Y	E	Y	L	A	E	A	S	V	V	F	P	K	V	F	P	V	V	H	N	L	L	D	S	K	I	N	T	L	L	S	L	C	Q	D	P	N	L	L	N	P	I	H	G	I	V	Q	S	V	V	Y	H	E	E	S	P	P	Q	Y	Q	T	S	Y
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																			T	T	T	G	G	G	G																																			T	T	S			S	S		T	T
	.	.	.	.	.	.	.	.	.	2390	.	.	.	.	.	.	.	.	.	2400	.	.	.	.	.	.	.	.	.	2410	.	.	.	.	.	.	.	.	.	2420	.	.	.
Sequence	L	Q	S	F	G	F	N	G	L	W	R	F	A	G	P	F	S	K	Q	T	Q	I	P	D	Y	A	E	L	I	V	K	F	L	D	A	L	I	D	T	Y	L	P	G
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)				T	T	T	T	S					T	S				S	S					S