PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.0

Fold library entry viewer: c6z2xE_

Fold library id	PDB Header	Molecule	Title
c6z2xE_	3.20	PDB header: hydrolase	Chain: E: PDB Molecule: serine/threonine-protein kinase mec1;

Links to external resources
Added to library: Sat Nov 14 10:39:07 2020

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence E S H V K Y L D E L I L A I K D L N S G V D S K V Q I K K V P S L K I L N T L I R N L K D Q R R N N I M K N D T I F S K T V S A L A L L L E

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S T S
S S S
S
T T T S
S S S T T S S

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence Y N P F L L V M K D S N G N F E I Q R L I D D F L N I S V L N Y D N Y H R I W F M R R K L G S W C K A C V E F Y G K P A K F Q L T A H F E N

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S
T T S T T S
T T T S
T T T
S
T T T S T T T
T T T

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence T M N L Y E Q A L T E V L L G K T E L L K F Y D T L K G L Y I L L Y W F T S E Y S T F G N S I A F L D S S L G F T K F D F N F Q R L I R I V

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) G G G T S S
S T S
T T T S
S S S G G G
T T

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240 . . . . . . . . . 250 . . . . . . . . . 260 . . . . . . . . . 270 . . . . . . . . . 280

Sequence L Y V F D S C E L A A L E Y A E I Q L K Y I S L V V D Y V C N R T I S T A L D A P A L V C C E Q L K F V L T T M H H F L D N K Y G L L D N D

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T S S
S S S
S
T T
T T

. . . . . . . . . 290 . . . . . . . . . 300 . . . . . . . . . 310 . . . . . . . . . 320 . . . . . . . . . 330 . . . . . . . . . 340 . . . . . . . . . 350

Sequence P T M A K G I L R L Y S L C I S N D F S K C F V D H F P I D Q W A D F S Q S E H F P F T Q L T N K A L S I V Y F D L K R R S L P V E A L K Y

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T S S S T T S
T T S
T T
S S
S S S
S
G G G

. . . . . . . . . 360 . . . . . . . . . 370 . . . . . . . . . 380 . . . . . . . . . 390 . . . . . . . . . 400 . . . . . . . . . 410 . . . . . . . . . 420

Sequence D N K F N I W V Y Q S E P D S S L K N V T S P F D D R Y K Q L E K L R L L V L K K F N K T E R G T L L K Y R V N Q L S P G F F Q R A G N D F

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S S S
S S
T T T S S
S S
T T T T S
S
T T S S S
S S
S

. . . . . . . . . 430 . . . . . . . . . 440 . . . . . . . . . 450 . . . . . . . . . 460 . . . . . . . . . 470 . . . . . . . . . 480 . . . . . . . . . 490

Sequence K L I L N E A S V S I Q T C F K T N N I T R L T S W T V I L G R L A C L E S E K F S S T K D M D N W Y V C H L C D I E K T G N P F V R I N P

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T S
S S
T T T T T
S S S
S
T T T T S
S S
T T S S S
T

. . . . . . . . . 500 . . . . . . . . . 510 . . . . . . . . . 520 . . . . . . . . . 530 . . . . . . . . . 540 . . . . . . . . . 550 . . . . . . . . . 560

Sequence N R P E A A G K S E I F R I L H S N F L S H P N I D E F S E S L L S G I L F S L H R I F S H F Q P P K L T D G N G Q I N K S F K L V Q K C F

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T
B T T T T
T S S
T T T T S S
S B
S
S S S
S S

. . . . . . . . . 570 . . . . . . . . . 580 . . . . . . . . . 590 . . . . . . . . . 600 . . . . . . . . . 610 . . . . . . . . . 620 . . . . . . . . . 630

Sequence M N S N R Y L R L L S T R I I P L F N I S D S H N S E D E H T A T L I K F L Q S Q K L P V V K E N L V I A W T Q L T L T T S N D V F D T L L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T
S S T T S T
S S S S T T S T T
G G G T T

. . . . . . . . . 640 . . . . . . . . . 650 . . . . . . . . . 660 . . . . . . . . . 670 . . . . . . . . . 680 . . . . . . . . . 690 . . . . . . . . . 700

Sequence L K L I D I F N S D D Y S L R I M M T L Q I K N M A K I L K K T P Y Q L L S P I L P V L L R Q L G K N L V E R K V G F Q N L I E L L G Y S S

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T S S
T T T
T T T T T G G G T S T T T T T S
T

. . . . . . . . . 710 . . . . . . . . . 720 . . . . . . . . . 730 . . . . . . . . . 740 . . . . . . . . . 750 . . . . . . . . . 760 . . . . . . . . . 770

Sequence K T I L D I F Q R Y I I P Y A I I Q Y K S D V L S E I A K I M C D G D T S L I N Q M K V N L L K K N S R Q I F A V A L V K H G L F S L D I L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T T T S S S T T S
S S
S T T S S S S
S T S

. . . . . . . . . 780 . . . . . . . . . 790 . . . . . . . . . 800 . . . . . . . . . 810 . . . . . . . . . 820 . . . . . . . . . 830 . . . . . . . . . 840

Sequence E T L F L N R A P T F D K G Y I T A Y L P D Y K T L A E I T K L Y K N S V T K D A S D S E N A N M I L C S L R F L I T N F E K D K R H G S K

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T
T T
T T S S S T T
S S S T T
S S
S S S S S S
S S
T T

. . . . . . . . . 850 . . . . . . . . . 860 . . . . . . . . . 870 . . . . . . . . . 880 . . . . . . . . . 890 . . . . . . . . . 900 . . . . . . . . . 910

Sequence Y K N I N N W T D D Q E Q A F Q K K L Q D N I L G I F Q V F S S D I H D V E G R T T Y Y E K L R V I N G I S F L I I Y A P K K S I I S A L A

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T
S T T
G G G T T S S
T T
T S S
S T

. . . . . . . . . 920 . . . . . . . . . 930 . . . . . . . . . 940 . . . . . . . . . 950 . . . . . . . . . 960 . . . . . . . . . 970 . . . . . . . . . 980

Sequence Q I S I C L Q T G L G L K E V R Y E A F R C W H L L V R H L N D E E L S T V I D S L I A F I L Q K W S E F N G K L R N I V Y S I L D T L I K

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S S T T S S
T T T S T
T T

. . . . . . . . . 990 . . . . . . . . . 1000 . . . . . . . . . 1010 . . . . . . . . . 1020 . . . . . . . . . 1030 . . . . . . . . . 1040 . . . . . . . . . 1050

Sequence E K S D L I L K L K P Y T T L A L V G K P E L G I L A R D G Q F A R M V N K I R S T T D L I P I F A N N L K S S N K Y V I N Q N L D D I E V

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T T T
T T
T T T
T T T
S T T S S
S T T T T
S T T

. . . . . . . . . 1060 . . . . . . . . . 1070 . . . . . . . . . 1080 . . . . . . . . . 1090 . . . . . . . . . 1100 . . . . . . . . . 1110 . . . . . . . . . 1120

Sequence Y L R R K Q T E R S I D F T P S D I T L V L G A L L D T S H K F R N L D K D L C E K C A K C I S M I G V L D V T K H E F K R T T Y S E N E V

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T
T T T S
T T T
T T S S S T T

. . . . . . . . . 1130 . . . . . . . . . 1140 . . . . . . . . . 1150 . . . . . . . . . 1160 . . . . . . . . . 1170 . . . . . . . . . 1180 . . . . . . . . . 1190

Sequence Y D L N D S V Q T I K F L I W V I N D I L V P A F W Q S E N P S K Q L F V A L V I Q E S L K Y C G L S S E S W D M N H K E L Y P N E A K L W

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S S T S
S S T T
S S S
T T T T

. . . . . . . . . 1200 . . . . . . . . . 1210 . . . . . . . . . 1220 . . . . . . . . . 1230 . . . . . . . . . 1240 . . . . . . . . . 1250 . . . . . . . . . 1260

Sequence E K F N S V S K T T I Y P L L S S L Y L A Q S W K E Y V P L K Y P S N N F K E G Y K I W V K R F T L D L L K T G T T E N H P L H V F S S L I

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T S
S G G G S
S
T T S
T T T
T S S
T T T S T T S G G G G G G

. . . . . . . . . 1270 . . . . . . . . . 1280 . . . . . . . . . 1290 . . . . . . . . . 1300 . . . . . . . . . 1310 . . . . . . . . . 1320 . . . . . . . . . 1330

Sequence R E D D G S L S N F L L P Y I S L D I I I K A E K G T P Y A D I L N G I I I E F D S I F T C N L E G M N N L Q V D S L R M C Y E S I F R V F

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) G S
S T
S S T T S S
S S S
T T

. . . . . . . . . 1340 . . . . . . . . . 1350 . . . . . . . . . 1360 . . . . . . . . . 1370 . . . . . . . . . 1380 . . . . . . . . . 1390 . . . . . . . . . 1400

Sequence E Y C K K W A T E F K Q N Y S K L H G T F I I K D T K T T N M L L R I D E F L R T T P S D L L A Q R S L E T D S F E R S A L Y L E Q C Y R Q

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T S
S S
S S S T T S S S S
S S S T T T T T
S

. . . . . . . . . 1410 . . . . . . . . . 1420 . . . . . . . . . 1430 . . . . . . . . . 1440 . . . . . . . . . 1450 . . . . . . . . . 1460 . . . . . . . . . 1470

Sequence N P H D K N Q N G Q L L K N L Q I T Y E E I G D I D S L D G V L R T F A T G N L V S K I E E L Q Y S E N W K L A Q D C F N V L G K F S D D P

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S
T T S S
T T T T T T T T T T S S
T T T S S
S
T T G G G T T
T T S
S
S

. . . . . . . . . 1480 . . . . . . . . . 1490 . . . . . . . . . 1500 . . . . . . . . . 1510 . . . . . . . . . 1520 . . . . . . . . . 1530 . . . . . . . . . 1540

Sequence K T T T R M L K S M Y D H Q L Y S Q I I S N S S F H S S D G K I S L S P D V K E W Y S I G L E A A N L E G N V Q T L K N W V E Q I E S L R N

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T T
T
T T T
S S S S
S S
S S S
T T
S

. . . . . . . . . 1550 . . . . . . . . . 1560 . . . . . . . . . 1570 . . . . . . . . . 1580 . . . . . . . . . 1590 . . . . . . . . . 1600 . . . . . . . . . 1610

Sequence I D D R E V L L Q Y N I A K A L I A I S N E D P L R T Q K Y I H N S F R L I G T N F I T S S K E T T L L K K Q N L L M K L H S L Y D L S F L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T T T
T T
T T T S
S T T T

. . . . . . . . . 1620 . . . . . . . . . 1630 . . . . . . . . . 1640 . . . . . . . . . 1650 . . . . . . . . . 1660 . . . . . . . . . 1670 . . . . . . . . . 1680

Sequence S S A K D K F E Y K S N T T I L D Y R M E R I G A D F V P N H Y I L S M R K S F D Q L K M N E Q A D A D L G K T F F T L A Q L A R N N A R L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S
S S T T S S
S
T T S
T T

. . . . . . . . . 1690 . . . . . . . . . 1700 . . . . . . . . . 1710 . . . . . . . . . 1720 . . . . . . . . . 1730 . . . . . . . . . 1740 . . . . . . . . . 1750

Sequence D I A S E S L M H C L E R R L P Q A E L E F A E I L W K Q G E N D R A L K I V Q E I H E K Y Q E N S S V N A R D R A A V L L K F T E W L D L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T T
S S S
G G G S S
S
T T T T T T

. . . . . . . . . 1760 . . . . . . . . . 1770 . . . . . . . . . 1780 . . . . . . . . . 1790 . . . . . . . . . 1800 . . . . . . . . . 1810 . . . . . . . . . 1820

Sequence S N N S A S E Q I I K Q Y Q D I F Q I D S K W D K P Y Y S I G L Y Y S R L L E R K K A E G Y I T N G R F E Y R A I S Y F L L A F E K N T A K

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T
S
S
S T S S
S T T T
S

. . . . . . . . . 1830 . . . . . . . . . 1840 . . . . . . . . . 1850 . . . . . . . . . 1860 . . . . . . . . . 1870 . . . . . . . . . 1880 . . . . . . . . . 1890

Sequence V R E N L P K V I T F W L D I A A A S I S E A P R K E M L S K A T E D I C S H V E E A L Q H C P T Y I W Y F V L T Q L L S R L L H S H Q S S

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T T T T T T T T S
T T S
S G G G G G G T T
S
S S S

. . . . . . . . . 1900 . . . . . . . . . 1910 . . . . . . . . . 1920 . . . . . . . . . 1930 . . . . . . . . . 1940 . . . . . . . . . 1950 . . . . . . . . . 1960

Sequence A Q I I M H I L L S L A V E Y P S H I L W Y I T A L V N S N S S K R V L R G K H I L E K Y R Q H S Q N P H D L V S S A L D L T K A L T R V C

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S S S
S S T T S S
S S T T

. . . . . . . . . 1970 . . . . . . . . . 1980 . . . . . . . . . 1990 . . . . . . . . . 2000 . . . . . . . . . 2010 . . . . . . . . . 2020 . . . . . . . . . 2030

Sequence L Q D V K F K F D M N V A P S A M V V P V R K N L D I I S P L E G Y Q P F R P V V S I I R F G S S Y K V F S S L K K P K Q L N I I G S D G N

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T
T T
S
S S B
S
S S
B
S
S S S S
S S

. . . . . . . . . 2040 . . . . . . . . . 2050 . . . . . . . . . 2060 . . . . . . . . . 2070 . . . . . . . . . 2080 . . . . . . . . . 2090 . . . . . . . . . 2100

Sequence I Y G I M C K K E D V R Q D N Q Y M Q F A T T M D F L L S K D I A S R K R S L G I N I Y S V L S L R E D C G I L E M V P N V V T L R S I L S

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S S
T T T
T T T
S T T
S S

. . . . . . . . . 2110 . . . . . . . . . 2120 . . . . . . . . . 2130 . . . . . . . . . 2140 . . . . . . . . . 2150 . . . . . . . . . 2160 . . . . . . . . . 2170

Sequence T K Y E S L K I K Y S L K S L H D R W Q H T A V D G K L E F Y M E Q V D K F P P I L Y Q W F L E N F P D P I N W F N A R N T Y A R S Y A V M

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T T T
S S T T S
S S S
S

. . . . . . . . . 2180 . . . . . . . . . 2190 . . . . . . . . . 2200 . . . . . . . . . 2210 . . . . . . . . . 2220 . . . . . . . . . 2230 . . . . . . . . . 2240

Sequence A M V G H I L G L G D R H C E N I L L D I Q T G K V L H V D L D C L F E K G K R L P V P E I V P F R L T P N L L D A L G I I G T E G T F K K

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T
G G G T T T
T T G G G S S S S
S S
S
S S T T T T

. . . . . . . . . 2250 . . . . . . . . . 2260 . . . . . . . . . 2270 . . . . . . . . . 2280 . . . . . . . . . 2290 . . . . . . . . . 2300 . . . . . . . . . 2310

Sequence S S E V T L A L M R K N E V A L M N V I E T I M Y D R N M D H S I Q K A L K V L R N K I R G I D P Q D G L V L S V A G Q T E T L I Q E A T S

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T T S
S
S T B
S S S
B
S

. . . . . . . . . 2320 . . . . .

Sequence E D N L S K M Y I G W L P F W

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T S
G G G
S

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Please cite: The Phyre2 web portal for protein modeling, prediction and analysis

Kelley LA et al. Nature Protocols 10, 845-858 (2015) [paper] [Citation link]

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	E	S	H	V	K	Y	L	D	E	L	I	L	A	I	K	D	L	N	S	G	V	D	S	K	V	Q	I	K	K	V	P	S	L	K	I	L	N	T	L	I	R	N	L	K	D	Q	R	R	N	N	I	M	K	N	D	T	I	F	S	K	T	V	S	A	L	A	L	L	L	E
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			S														T	S		S	S	S						S																T	T	T	S		S	S	S	T	T	S	S
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	Y	N	P	F	L	L	V	M	K	D	S	N	G	N	F	E	I	Q	R	L	I	D	D	F	L	N	I	S	V	L	N	Y	D	N	Y	H	R	I	W	F	M	R	R	K	L	G	S	W	C	K	A	C	V	E	F	Y	G	K	P	A	K	F	Q	L	T	A	H	F	E	N
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	S		T	T	S	T	T	S			T	T	T	S		T														T	T		S																	T	T	T	S	T	T	T						T	T	T
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	T	M	N	L	Y	E	Q	A	L	T	E	V	L	L	G	K	T	E	L	L	K	F	Y	D	T	L	K	G	L	Y	I	L	L	Y	W	F	T	S	E	Y	S	T	F	G	N	S	I	A	F	L	D	S	S	L	G	F	T	K	F	D	F	N	F	Q	R	L	I	R	I	V
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)										G	G	G	T	S	S				S																		T	S		T	T	T	S		S	S	S	G	G	G				T	T
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280
Sequence	L	Y	V	F	D	S	C	E	L	A	A	L	E	Y	A	E	I	Q	L	K	Y	I	S	L	V	V	D	Y	V	C	N	R	T	I	S	T	A	L	D	A	P	A	L	V	C	C	E	Q	L	K	F	V	L	T	T	M	H	H	F	L	D	N	K	Y	G	L	L	D	N	D
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																															T	S	S				S	S	S					S																		T	T					T	T
	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350
Sequence	P	T	M	A	K	G	I	L	R	L	Y	S	L	C	I	S	N	D	F	S	K	C	F	V	D	H	F	P	I	D	Q	W	A	D	F	S	Q	S	E	H	F	P	F	T	Q	L	T	N	K	A	L	S	I	V	Y	F	D	L	K	R	R	S	L	P	V	E	A	L	K	Y
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)													T	T	S	S	S	T	T								S			T	T	S			T	T		S	S		S	S	S																				S		G	G	G
	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence	D	N	K	F	N	I	W	V	Y	Q	S	E	P	D	S	S	L	K	N	V	T	S	P	F	D	D	R	Y	K	Q	L	E	K	L	R	L	L	V	L	K	K	F	N	K	T	E	R	G	T	L	L	K	Y	R	V	N	Q	L	S	P	G	F	F	Q	R	A	G	N	D	F
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)		S	S	S	S								S	S				T	T	T	S	S				S	S		T	T											T	T	S			S											T	T	S	S	S			S	S			S
	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490
Sequence	K	L	I	L	N	E	A	S	V	S	I	Q	T	C	F	K	T	N	N	I	T	R	L	T	S	W	T	V	I	L	G	R	L	A	C	L	E	S	E	K	F	S	S	T	K	D	M	D	N	W	Y	V	C	H	L	C	D	I	E	K	T	G	N	P	F	V	R	I	N	P
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)													T	S		S	S			T	T																		T	T	T						S	S	S			S		T	T	T	T	S			S	S		T	T	S	S	S		T
	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560
Sequence	N	R	P	E	A	A	G	K	S	E	I	F	R	I	L	H	S	N	F	L	S	H	P	N	I	D	E	F	S	E	S	L	L	S	G	I	L	F	S	L	H	R	I	F	S	H	F	Q	P	P	K	L	T	D	G	N	G	Q	I	N	K	S	F	K	L	V	Q	K	C	F
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T			B	T	T	T	T											T	S	S		T	T	T	T	S	S																			S	B				S			S	S	S				S	S
	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630
Sequence	M	N	S	N	R	Y	L	R	L	L	S	T	R	I	I	P	L	F	N	I	S	D	S	H	N	S	E	D	E	H	T	A	T	L	I	K	F	L	Q	S	Q	K	L	P	V	V	K	E	N	L	V	I	A	W	T	Q	L	T	L	T	T	S	N	D	V	F	D	T	L	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T		S	S								T	T	S					T			S	S	S	S	T	T	S											T	T				G	G	G													T	T
	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.	.	660	.	.	.	.	.	.	.	.	.	670	.	.	.	.	.	.	.	.	.	680	.	.	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700
Sequence	L	K	L	I	D	I	F	N	S	D	D	Y	S	L	R	I	M	M	T	L	Q	I	K	N	M	A	K	I	L	K	K	T	P	Y	Q	L	L	S	P	I	L	P	V	L	L	R	Q	L	G	K	N	L	V	E	R	K	V	G	F	Q	N	L	I	E	L	L	G	Y	S	S
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)								T	S	S																		T	T	T								T	T	T					T	T	G	G	G	T	S	T	T	T	T												T	S		T
	.	.	.	.	.	.	.	.	.	710	.	.	.	.	.	.	.	.	.	720	.	.	.	.	.	.	.	.	.	730	.	.	.	.	.	.	.	.	.	740	.	.	.	.	.	.	.	.	.	750	.	.	.	.	.	.	.	.	.	760	.	.	.	.	.	.	.	.	.	770
Sequence	K	T	I	L	D	I	F	Q	R	Y	I	I	P	Y	A	I	I	Q	Y	K	S	D	V	L	S	E	I	A	K	I	M	C	D	G	D	T	S	L	I	N	Q	M	K	V	N	L	L	K	K	N	S	R	Q	I	F	A	V	A	L	V	K	H	G	L	F	S	L	D	I	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T	T	T	T	S	S	S									T	T	S		S	S		S									T	T	S	S	S	S													S											T	S
	.	.	.	.	.	.	.	.	.	780	.	.	.	.	.	.	.	.	.	790	.	.	.	.	.	.	.	.	.	800	.	.	.	.	.	.	.	.	.	810	.	.	.	.	.	.	.	.	.	820	.	.	.	.	.	.	.	.	.	830	.	.	.	.	.	.	.	.	.	840
Sequence	E	T	L	F	L	N	R	A	P	T	F	D	K	G	Y	I	T	A	Y	L	P	D	Y	K	T	L	A	E	I	T	K	L	Y	K	N	S	V	T	K	D	A	S	D	S	E	N	A	N	M	I	L	C	S	L	R	F	L	I	T	N	F	E	K	D	K	R	H	G	S	K
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)						T	T		T	T		T	T	S	S	S	T	T		S	S	S									T	T					S	S																				S	S	S	S	S	S		S	S			T	T
	.	.	.	.	.	.	.	.	.	850	.	.	.	.	.	.	.	.	.	860	.	.	.	.	.	.	.	.	.	870	.	.	.	.	.	.	.	.	.	880	.	.	.	.	.	.	.	.	.	890	.	.	.	.	.	.	.	.	.	900	.	.	.	.	.	.	.	.	.	910
Sequence	Y	K	N	I	N	N	W	T	D	D	Q	E	Q	A	F	Q	K	K	L	Q	D	N	I	L	G	I	F	Q	V	F	S	S	D	I	H	D	V	E	G	R	T	T	Y	Y	E	K	L	R	V	I	N	G	I	S	F	L	I	I	Y	A	P	K	K	S	I	I	S	A	L	A
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T	T		S	T	T			G	G	G										T	T	S												S		T	T					T																S	S		S						T
	.	.	.	.	.	.	.	.	.	920	.	.	.	.	.	.	.	.	.	930	.	.	.	.	.	.	.	.	.	940	.	.	.	.	.	.	.	.	.	950	.	.	.	.	.	.	.	.	.	960	.	.	.	.	.	.	.	.	.	970	.	.	.	.	.	.	.	.	.	980
Sequence	Q	I	S	I	C	L	Q	T	G	L	G	L	K	E	V	R	Y	E	A	F	R	C	W	H	L	L	V	R	H	L	N	D	E	E	L	S	T	V	I	D	S	L	I	A	F	I	L	Q	K	W	S	E	F	N	G	K	L	R	N	I	V	Y	S	I	L	D	T	L	I	K
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)												S	S	T	T														S	S						T	T	T	S										T		T	T
	.	.	.	.	.	.	.	.	.	990	.	.	.	.	.	.	.	.	.	1000	.	.	.	.	.	.	.	.	.	1010	.	.	.	.	.	.	.	.	.	1020	.	.	.	.	.	.	.	.	.	1030	.	.	.	.	.	.	.	.	.	1040	.	.	.	.	.	.	.	.	.	1050
Sequence	E	K	S	D	L	I	L	K	L	K	P	Y	T	T	L	A	L	V	G	K	P	E	L	G	I	L	A	R	D	G	Q	F	A	R	M	V	N	K	I	R	S	T	T	D	L	I	P	I	F	A	N	N	L	K	S	S	N	K	Y	V	I	N	Q	N	L	D	D	I	E	V
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T	T						T	T		T								T		T	T	T			T	T	T		S										T	T	S	S			S					T	T	T	T			S	T	T
	.	.	.	.	.	.	.	.	.	1060	.	.	.	.	.	.	.	.	.	1070	.	.	.	.	.	.	.	.	.	1080	.	.	.	.	.	.	.	.	.	1090	.	.	.	.	.	.	.	.	.	1100	.	.	.	.	.	.	.	.	.	1110	.	.	.	.	.	.	.	.	.	1120
Sequence	Y	L	R	R	K	Q	T	E	R	S	I	D	F	T	P	S	D	I	T	L	V	L	G	A	L	L	D	T	S	H	K	F	R	N	L	D	K	D	L	C	E	K	C	A	K	C	I	S	M	I	G	V	L	D	V	T	K	H	E	F	K	R	T	T	Y	S	E	N	E	V
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)									T																							T	T	T	S																				T	T	T						T	T	S	S	S	T	T
	.	.	.	.	.	.	.	.	.	1130	.	.	.	.	.	.	.	.	.	1140	.	.	.	.	.	.	.	.	.	1150	.	.	.	.	.	.	.	.	.	1160	.	.	.	.	.	.	.	.	.	1170	.	.	.	.	.	.	.	.	.	1180	.	.	.	.	.	.	.	.	.	1190
Sequence	Y	D	L	N	D	S	V	Q	T	I	K	F	L	I	W	V	I	N	D	I	L	V	P	A	F	W	Q	S	E	N	P	S	K	Q	L	F	V	A	L	V	I	Q	E	S	L	K	Y	C	G	L	S	S	E	S	W	D	M	N	H	K	E	L	Y	P	N	E	A	K	L	W
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			S	S	S															T							S		S	S																		T	T		S	S	S			T	T	T	T
	.	.	.	.	.	.	.	.	.	1200	.	.	.	.	.	.	.	.	.	1210	.	.	.	.	.	.	.	.	.	1220	.	.	.	.	.	.	.	.	.	1230	.	.	.	.	.	.	.	.	.	1240	.	.	.	.	.	.	.	.	.	1250	.	.	.	.	.	.	.	.	.	1260
Sequence	E	K	F	N	S	V	S	K	T	T	I	Y	P	L	L	S	S	L	Y	L	A	Q	S	W	K	E	Y	V	P	L	K	Y	P	S	N	N	F	K	E	G	Y	K	I	W	V	K	R	F	T	L	D	L	L	K	T	G	T	T	E	N	H	P	L	H	V	F	S	S	L	I
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T	T	S									S	G	G	G	S									S							T	T	S			T	T	T															T	S	S		T	T	T	S	T	T	S	G	G	G	G	G	G
	.	.	.	.	.	.	.	.	.	1270	.	.	.	.	.	.	.	.	.	1280	.	.	.	.	.	.	.	.	.	1290	.	.	.	.	.	.	.	.	.	1300	.	.	.	.	.	.	.	.	.	1310	.	.	.	.	.	.	.	.	.	1320	.	.	.	.	.	.	.	.	.	1330
Sequence	R	E	D	D	G	S	L	S	N	F	L	L	P	Y	I	S	L	D	I	I	I	K	A	E	K	G	T	P	Y	A	D	I	L	N	G	I	I	I	E	F	D	S	I	F	T	C	N	L	E	G	M	N	N	L	Q	V	D	S	L	R	M	C	Y	E	S	I	F	R	V	F
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	G	S			S																T			S	S	T	T																		S	S			S	S	S		T	T
	.	.	.	.	.	.	.	.	.	1340	.	.	.	.	.	.	.	.	.	1350	.	.	.	.	.	.	.	.	.	1360	.	.	.	.	.	.	.	.	.	1370	.	.	.	.	.	.	.	.	.	1380	.	.	.	.	.	.	.	.	.	1390	.	.	.	.	.	.	.	.	.	1400
Sequence	E	Y	C	K	K	W	A	T	E	F	K	Q	N	Y	S	K	L	H	G	T	F	I	I	K	D	T	K	T	T	N	M	L	L	R	I	D	E	F	L	R	T	T	P	S	D	L	L	A	Q	R	S	L	E	T	D	S	F	E	R	S	A	L	Y	L	E	Q	C	Y	R	Q
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																	T	S		S	S				S	S	S										T	T	S	S	S	S		S	S	S	T	T					T	T	T															S
	.	.	.	.	.	.	.	.	.	1410	.	.	.	.	.	.	.	.	.	1420	.	.	.	.	.	.	.	.	.	1430	.	.	.	.	.	.	.	.	.	1440	.	.	.	.	.	.	.	.	.	1450	.	.	.	.	.	.	.	.	.	1460	.	.	.	.	.	.	.	.	.	1470
Sequence	N	P	H	D	K	N	Q	N	G	Q	L	L	K	N	L	Q	I	T	Y	E	E	I	G	D	I	D	S	L	D	G	V	L	R	T	F	A	T	G	N	L	V	S	K	I	E	E	L	Q	Y	S	E	N	W	K	L	A	Q	D	C	F	N	V	L	G	K	F	S	D	D	P
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	S		T	T	S	S		T	T	T	T	T	T	T	T	T					T	S	S			T	T						T	S	S			S							T	T	G	G	G	T	T													T	T	S		S		S
	.	.	.	.	.	.	.	.	.	1480	.	.	.	.	.	.	.	.	.	1490	.	.	.	.	.	.	.	.	.	1500	.	.	.	.	.	.	.	.	.	1510	.	.	.	.	.	.	.	.	.	1520	.	.	.	.	.	.	.	.	.	1530	.	.	.	.	.	.	.	.	.	1540
Sequence	K	T	T	T	R	M	L	K	S	M	Y	D	H	Q	L	Y	S	Q	I	I	S	N	S	S	F	H	S	S	D	G	K	I	S	L	S	P	D	V	K	E	W	Y	S	I	G	L	E	A	A	N	L	E	G	N	V	Q	T	L	K	N	W	V	E	Q	I	E	S	L	R	N
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)												T	T	T							T		T	T	T		S	S	S	S			S	S		S	S															S														T	T		S
	.	.	.	.	.	.	.	.	.	1550	.	.	.	.	.	.	.	.	.	1560	.	.	.	.	.	.	.	.	.	1570	.	.	.	.	.	.	.	.	.	1580	.	.	.	.	.	.	.	.	.	1590	.	.	.	.	.	.	.	.	.	1600	.	.	.	.	.	.	.	.	.	1610
Sequence	I	D	D	R	E	V	L	L	Q	Y	N	I	A	K	A	L	I	A	I	S	N	E	D	P	L	R	T	Q	K	Y	I	H	N	S	F	R	L	I	G	T	N	F	I	T	S	S	K	E	T	T	L	L	K	K	Q	N	L	L	M	K	L	H	S	L	Y	D	L	S	F	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)				T	T																T	T																			T	T				T	T	T	S		S	T	T	T
	.	.	.	.	.	.	.	.	.	1620	.	.	.	.	.	.	.	.	.	1630	.	.	.	.	.	.	.	.	.	1640	.	.	.	.	.	.	.	.	.	1650	.	.	.	.	.	.	.	.	.	1660	.	.	.	.	.	.	.	.	.	1670	.	.	.	.	.	.	.	.	.	1680
Sequence	S	S	A	K	D	K	F	E	Y	K	S	N	T	T	I	L	D	Y	R	M	E	R	I	G	A	D	F	V	P	N	H	Y	I	L	S	M	R	K	S	F	D	Q	L	K	M	N	E	Q	A	D	A	D	L	G	K	T	F	F	T	L	A	Q	L	A	R	N	N	A	R	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)		S		S	S															T	T	S	S		S																	T	T	S																							T	T
	.	.	.	.	.	.	.	.	.	1690	.	.	.	.	.	.	.	.	.	1700	.	.	.	.	.	.	.	.	.	1710	.	.	.	.	.	.	.	.	.	1720	.	.	.	.	.	.	.	.	.	1730	.	.	.	.	.	.	.	.	.	1740	.	.	.	.	.	.	.	.	.	1750
Sequence	D	I	A	S	E	S	L	M	H	C	L	E	R	R	L	P	Q	A	E	L	E	F	A	E	I	L	W	K	Q	G	E	N	D	R	A	L	K	I	V	Q	E	I	H	E	K	Y	Q	E	N	S	S	V	N	A	R	D	R	A	A	V	L	L	K	F	T	E	W	L	D	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)								T					T	T		S	S													S															G	G	G	S	S		S		T	T	T	T	T													T
	.	.	.	.	.	.	.	.	.	1760	.	.	.	.	.	.	.	.	.	1770	.	.	.	.	.	.	.	.	.	1780	.	.	.	.	.	.	.	.	.	1790	.	.	.	.	.	.	.	.	.	1800	.	.	.	.	.	.	.	.	.	1810	.	.	.	.	.	.	.	.	.	1820
Sequence	S	N	N	S	A	S	E	Q	I	I	K	Q	Y	Q	D	I	F	Q	I	D	S	K	W	D	K	P	Y	Y	S	I	G	L	Y	Y	S	R	L	L	E	R	K	K	A	E	G	Y	I	T	N	G	R	F	E	Y	R	A	I	S	Y	F	L	L	A	F	E	K	N	T	A	K
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T	T		S																		S		S																			T	S	S					S														T	T	T				S
	.	.	.	.	.	.	.	.	.	1830	.	.	.	.	.	.	.	.	.	1840	.	.	.	.	.	.	.	.	.	1850	.	.	.	.	.	.	.	.	.	1860	.	.	.	.	.	.	.	.	.	1870	.	.	.	.	.	.	.	.	.	1880	.	.	.	.	.	.	.	.	.	1890
Sequence	V	R	E	N	L	P	K	V	I	T	F	W	L	D	I	A	A	A	S	I	S	E	A	P	R	K	E	M	L	S	K	A	T	E	D	I	C	S	H	V	E	E	A	L	Q	H	C	P	T	Y	I	W	Y	F	V	L	T	Q	L	L	S	R	L	L	H	S	H	Q	S	S
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)		T	T	T					T	T	T	T	T	T								S																							T	T	S		S	G	G	G	G	G	G						T	T				S		S	S	S
	.	.	.	.	.	.	.	.	.	1900	.	.	.	.	.	.	.	.	.	1910	.	.	.	.	.	.	.	.	.	1920	.	.	.	.	.	.	.	.	.	1930	.	.	.	.	.	.	.	.	.	1940	.	.	.	.	.	.	.	.	.	1950	.	.	.	.	.	.	.	.	.	1960
Sequence	A	Q	I	I	M	H	I	L	L	S	L	A	V	E	Y	P	S	H	I	L	W	Y	I	T	A	L	V	N	S	N	S	S	K	R	V	L	R	G	K	H	I	L	E	K	Y	R	Q	H	S	Q	N	P	H	D	L	V	S	S	A	L	D	L	T	K	A	L	T	R	V	C
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)														S	S												S			S	S	T	T															S	S				S	S															T	T
	.	.	.	.	.	.	.	.	.	1970	.	.	.	.	.	.	.	.	.	1980	.	.	.	.	.	.	.	.	.	1990	.	.	.	.	.	.	.	.	.	2000	.	.	.	.	.	.	.	.	.	2010	.	.	.	.	.	.	.	.	.	2020	.	.	.	.	.	.	.	.	.	2030
Sequence	L	Q	D	V	K	F	K	F	D	M	N	V	A	P	S	A	M	V	V	P	V	R	K	N	L	D	I	I	S	P	L	E	G	Y	Q	P	F	R	P	V	V	S	I	I	R	F	G	S	S	Y	K	V	F	S	S	L	K	K	P	K	Q	L	N	I	I	G	S	D	G	N
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T										T	T		S		S	S	B			S															S	S					B						S						S	S	S	S										S	S
	.	.	.	.	.	.	.	.	.	2040	.	.	.	.	.	.	.	.	.	2050	.	.	.	.	.	.	.	.	.	2060	.	.	.	.	.	.	.	.	.	2070	.	.	.	.	.	.	.	.	.	2080	.	.	.	.	.	.	.	.	.	2090	.	.	.	.	.	.	.	.	.	2100
Sequence	I	Y	G	I	M	C	K	K	E	D	V	R	Q	D	N	Q	Y	M	Q	F	A	T	T	M	D	F	L	L	S	K	D	I	A	S	R	K	R	S	L	G	I	N	I	Y	S	V	L	S	L	R	E	D	C	G	I	L	E	M	V	P	N	V	V	T	L	R	S	I	L	S
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)								S	S		T																		T	T						T	T	T												S	T	T								S	S
	.	.	.	.	.	.	.	.	.	2110	.	.	.	.	.	.	.	.	.	2120	.	.	.	.	.	.	.	.	.	2130	.	.	.	.	.	.	.	.	.	2140	.	.	.	.	.	.	.	.	.	2150	.	.	.	.	.	.	.	.	.	2160	.	.	.	.	.	.	.	.	.	2170
Sequence	T	K	Y	E	S	L	K	I	K	Y	S	L	K	S	L	H	D	R	W	Q	H	T	A	V	D	G	K	L	E	F	Y	M	E	Q	V	D	K	F	P	P	I	L	Y	Q	W	F	L	E	N	F	P	D	P	I	N	W	F	N	A	R	N	T	Y	A	R	S	Y	A	V	M
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)				T	T	T	T					S	S	T	T							S		S	S													S														S
	.	.	.	.	.	.	.	.	.	2180	.	.	.	.	.	.	.	.	.	2190	.	.	.	.	.	.	.	.	.	2200	.	.	.	.	.	.	.	.	.	2210	.	.	.	.	.	.	.	.	.	2220	.	.	.	.	.	.	.	.	.	2230	.	.	.	.	.	.	.	.	.	2240
Sequence	A	M	V	G	H	I	L	G	L	G	D	R	H	C	E	N	I	L	L	D	I	Q	T	G	K	V	L	H	V	D	L	D	C	L	F	E	K	G	K	R	L	P	V	P	E	I	V	P	F	R	L	T	P	N	L	L	D	A	L	G	I	I	G	T	E	G	T	F	K	K
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)							T	T						G	G	G					T	T	T												T	T	G	G	G	S	S	S	S					S	S										S		S	S	T	T	T	T
	.	.	.	.	.	.	.	.	.	2250	.	.	.	.	.	.	.	.	.	2260	.	.	.	.	.	.	.	.	.	2270	.	.	.	.	.	.	.	.	.	2280	.	.	.	.	.	.	.	.	.	2290	.	.	.	.	.	.	.	.	.	2300	.	.	.	.	.	.	.	.	.	2310
Sequence	S	S	E	V	T	L	A	L	M	R	K	N	E	V	A	L	M	N	V	I	E	T	I	M	Y	D	R	N	M	D	H	S	I	Q	K	A	L	K	V	L	R	N	K	I	R	G	I	D	P	Q	D	G	L	V	L	S	V	A	G	Q	T	E	T	L	I	Q	E	A	T	S
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)												T									T	T					S		S		S															T	B		S	S	S			B															S
	.	.	.	.	.	.	.	.	.	2320	.	.	.	.	.
Sequence	E	D	N	L	S	K	M	Y	I	G	W	L	P	F	W
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)					T	T	S		G	G	G		S