PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.0

Fold library entry viewer: c6pkwB_

Fold library id	PDB Header	Molecule	Title
c6pkwB_	4.50	PDB header: transport protein	Chain: B: PDB Molecule: transient receptor potential cation channel subfamily m

Links to external resources
Added to library: Sat Aug 31 08:44:15 2019

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence L A S W I K E N I K G K Y V R V S S D T S C E N L Y Q L M T E Q D K F R R G L I K V A Q L T G G T H A G V M K H V G M A V R D Y T H F L L V

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S
S S S S T

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence D D G T Q G H Y G V E I E L R A R L E K L I S K L G V T I P V V C V L N T I Y N S M L N H T P C V T M A L I N R L L K R F F M E L Q I I E W

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S
S S
S S
B
T T
B
T T T T T T T T

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence T K K I Q D I L R M P H L L T V D V A I L Q A L L K A S R S D E H C W E R Q L E L A V A W N R V D I A E S E I F T W T S S D L H P A M F S A

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T
T T B
T
S
G G G G

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240 . . . . . . . . . 250 . . . . . . . . . 260 . . . . . . . . . 270 . . . . . . . . . 280

Sequence L V G D K P E F V R L L L E N G V C V R E F L E R E E T L C E L Y S H L P S C F F L R K L A K R V Q C L S H V S E E V R H L L G S F T Q P L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T S
T
T
S
T T S

. . . . . . . . . 290 . . . . . . . . . 300 . . . . . . . . . 310 . . . . . . . . . 320 . . . . . . . . . 330 . . . . . . . . . 340 . . . . . . . . . 350

Sequence Y I A S R Y K D T V W D P G R D L F L W A V V Q N N R E L A E I G W E Q C R D C I A A A L A A S K I L R K L A Q E S E A T E M L E L A N H Y

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S
T
S S
S

. . . . . . . . . 360 . . . . . . . . . 370 . . . . . . . . . 380 . . . . . . . . . 390 . . . . . . . . . 400 . . . . . . . . . 410 . . . . . . . . . 420

Sequence E K Q A I G V F S E C H S W D A Q R A Q K L L I R I S P S W G R S T C L W L A L E A H D K S F I A H S G V Q A L L T Q I W C G E L S V D N P

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T B B
S S S S S
B
S S T T B
T T S

. . . . . . . . . 430 . . . . . . . . . 440 . . . . . . . . . 450 . . . . . . . . . 460 . . . . . . . . . 470 . . . . . . . . . 480 . . . . . . . . . 490

Sequence H W K V L L C M I F F P L I Y T G F L T F R R D E D I Q R Q A E R T E Q C S S R L M S F L K S P Q V K F Y W N I A S Y F G F L W L F A V V L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T S G G G G G S S
S
B T
T

. . . . . . . . . 500 . . . . . . . . . 510 . . . . . . . . . 520 . . . . . . . . . 530 . . . . . . . . . 540 . . . . . . . . . 550 . . . . . . . . . 560

Sequence M S W R E L L L Y V W L T S L V C E E I R Q L Y H D G F R R K A K M Y I K D L W N I L D V L S I V L F I A G L I C R L Q A S D T V F Y I G K

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T
S S S
S

. . . . . . . . . 570 . . . . . . . . . 580 . . . . . . . . . 590 . . . . . . . . . 600 . . . . . . . . . 610 . . . . . . . . . 620 . . . . . . . . . 630

Sequence V I L C I D F I I F C L R L M A I F S I S R T L G P K I I I V R R M M L D L F F F M F L L S I W V V A Y G V A K Q G I L I E N E E R L N W I

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T S T T T T T S S S
S

. . . . . . . . . 640 . . . . . . . . . 650 . . . . . . . . . 660 . . . . . . . . . 670 . . . . . . . . . 680 . . . . . . . . . 690 . . . . . . . . . 700

Sequence I R G A V Y E P Y I T I F T P V F P E W L T I M M L C V Y L L F A N I L L L N L L I A I F N Y D N T D T I W K F Q R Y E L I K E Y H S R P A

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S
S
S

. . . . . . . . . 710 . . . . . . . . . 720 . . . . . . . . . 730 . . . . . . . . . 740 . . . . . . . . . 750 . . . . . . . . . 760 . . . . . . . . . 770

Sequence L P P P F I L L S H L I L F I R G V F L R H K N F R Q E L E Q T E E E E L L S W E A Y M K D N Y L A S T R Q D E S Q S V E H R I H D T A E K

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S
S S
B
T T

. . . . . . . . . 780 . . . . . . . . . 790 . . . . . . . . . 800 . . . . . . . . . 810 . . . . . . . . . 820 . . . . . . . . . 830 . . . . . . . . . 840

Sequence V G A M S E L L E R E Q E M V X X X X X X X X X X X X X X X X X X X X X X D E E A P H M F A R Q L Q Y P D S T V R R F P V P E E K V S W E V

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S
S S T T T T
S S S
S S
S T T S

. . . . . . . . . 850 . . . . . . . . . 860 . . . . . . . . . 870 . . . . . . . . . 880 . . . . . . . . . 890 . . . . . . . . . 900 . . . . . . . . . 910

Sequence N F S P Y Q P P V Y N Q K H R N P G G R T G I R G K G A L N T L G P N H I L H P I F T R W R D K V L E F L A V W R W A L L G G P A L A Q V L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S
S
T T
S
T T S S S S
B
B

. . . . . . . . . 920 . . . . . . . . . 930 . . . . . . . . . 940 . . . . . . . . . 950 . . . . . . . . . 960 . . . . . . . . . 970 . . . . . . . . . 980

Sequence E R I L G K K L N E G E E V Y K G Y V D D S R N T D N A W V E T S I I T L H C D K N T M A D L N H M V E L Q W R E V S S D A C R C S Y Q R E

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T
T T
S S
T T T S S
S S S
S S

. . . . . .

Sequence A L R Q I A

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)

Download: PDB structure FASTA sequence
Hidden Markov model

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Please cite: The Phyre2 web portal for protein modeling, prediction and analysis

Kelley LA et al. Nature Protocols 10, 845-858 (2015) [paper] [Citation link]

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	L	A	S	W	I	K	E	N	I	K	G	K	Y	V	R	V	S	S	D	T	S	C	E	N	L	Y	Q	L	M	T	E	Q	D	K	F	R	R	G	L	I	K	V	A	Q	L	T	G	G	T	H	A	G	V	M	K	H	V	G	M	A	V	R	D	Y	T	H	F	L	L	V
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																		S	S																														S	S	S	S	T
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	D	D	G	T	Q	G	H	Y	G	V	E	I	E	L	R	A	R	L	E	K	L	I	S	K	L	G	V	T	I	P	V	V	C	V	L	N	T	I	Y	N	S	M	L	N	H	T	P	C	V	T	M	A	L	I	N	R	L	L	K	R	F	F	M	E	L	Q	I	I	E	W
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			S		S	S				S	S																						B											T	T			B			T	T	T	T	T					T	T	T
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	T	K	K	I	Q	D	I	L	R	M	P	H	L	L	T	V	D	V	A	I	L	Q	A	L	L	K	A	S	R	S	D	E	H	C	W	E	R	Q	L	E	L	A	V	A	W	N	R	V	D	I	A	E	S	E	I	F	T	W	T	S	S	D	L	H	P	A	M	F	S	A
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)								T	T			T	T	B																																T		S												G	G	G	G
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280
Sequence	L	V	G	D	K	P	E	F	V	R	L	L	L	E	N	G	V	C	V	R	E	F	L	E	R	E	E	T	L	C	E	L	Y	S	H	L	P	S	C	F	F	L	R	K	L	A	K	R	V	Q	C	L	S	H	V	S	E	E	V	R	H	L	L	G	S	F	T	Q	P	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)		T	S													T																			T			S																											T	T	S
	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350
Sequence	Y	I	A	S	R	Y	K	D	T	V	W	D	P	G	R	D	L	F	L	W	A	V	V	Q	N	N	R	E	L	A	E	I	G	W	E	Q	C	R	D	C	I	A	A	A	L	A	A	S	K	I	L	R	K	L	A	Q	E	S	E	A	T	E	M	L	E	L	A	N	H	Y
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			S	S																					T													S	S																						S
	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence	E	K	Q	A	I	G	V	F	S	E	C	H	S	W	D	A	Q	R	A	Q	K	L	L	I	R	I	S	P	S	W	G	R	S	T	C	L	W	L	A	L	E	A	H	D	K	S	F	I	A	H	S	G	V	Q	A	L	L	T	Q	I	W	C	G	E	L	S	V	D	N	P
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																								T	B	B		S	S	S	S	S		B															S	S													T	T	B		T	T	S
	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490
Sequence	H	W	K	V	L	L	C	M	I	F	F	P	L	I	Y	T	G	F	L	T	F	R	R	D	E	D	I	Q	R	Q	A	E	R	T	E	Q	C	S	S	R	L	M	S	F	L	K	S	P	Q	V	K	F	Y	W	N	I	A	S	Y	F	G	F	L	W	L	F	A	V	V	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T	T								S	G	G	G	G	G	S	S		S		B														T											T
	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560
Sequence	M	S	W	R	E	L	L	L	Y	V	W	L	T	S	L	V	C	E	E	I	R	Q	L	Y	H	D	G	F	R	R	K	A	K	M	Y	I	K	D	L	W	N	I	L	D	V	L	S	I	V	L	F	I	A	G	L	I	C	R	L	Q	A	S	D	T	V	F	Y	I	G	K
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																								T														S	S																					S		S
	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630
Sequence	V	I	L	C	I	D	F	I	I	F	C	L	R	L	M	A	I	F	S	I	S	R	T	L	G	P	K	I	I	I	V	R	R	M	M	L	D	L	F	F	F	M	F	L	L	S	I	W	V	V	A	Y	G	V	A	K	Q	G	I	L	I	E	N	E	E	R	L	N	W	I
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																				T	S	T	T						T	T							T																							S	S	S					S
	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.	.	660	.	.	.	.	.	.	.	.	.	670	.	.	.	.	.	.	.	.	.	680	.	.	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700
Sequence	I	R	G	A	V	Y	E	P	Y	I	T	I	F	T	P	V	F	P	E	W	L	T	I	M	M	L	C	V	Y	L	L	F	A	N	I	L	L	L	N	L	L	I	A	I	F	N	Y	D	N	T	D	T	I	W	K	F	Q	R	Y	E	L	I	K	E	Y	H	S	R	P	A
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																S	S																																																			S		S
	.	.	.	.	.	.	.	.	.	710	.	.	.	.	.	.	.	.	.	720	.	.	.	.	.	.	.	.	.	730	.	.	.	.	.	.	.	.	.	740	.	.	.	.	.	.	.	.	.	750	.	.	.	.	.	.	.	.	.	760	.	.	.	.	.	.	.	.	.	770
Sequence	L	P	P	P	F	I	L	L	S	H	L	I	L	F	I	R	G	V	F	L	R	H	K	N	F	R	Q	E	L	E	Q	T	E	E	E	E	L	L	S	W	E	A	Y	M	K	D	N	Y	L	A	S	T	R	Q	D	E	S	Q	S	V	E	H	R	I	H	D	T	A	E	K
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	S																							S	S		B																														T	T
	.	.	.	.	.	.	.	.	.	780	.	.	.	.	.	.	.	.	.	790	.	.	.	.	.	.	.	.	.	800	.	.	.	.	.	.	.	.	.	810	.	.	.	.	.	.	.	.	.	820	.	.	.	.	.	.	.	.	.	830	.	.	.	.	.	.	.	.	.	840
Sequence	V	G	A	M	S	E	L	L	E	R	E	Q	E	M	V	X	X	X	X	X	X	X	X	X	X	X	X	X	X	X	X	X	X	X	X	X	X	D	E	E	A	P	H	M	F	A	R	Q	L	Q	Y	P	D	S	T	V	R	R	F	P	V	P	E	E	K	V	S	W	E	V
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																																			S									S	S	T	T	T	T		S	S	S		S	S											S	T	T	S
	.	.	.	.	.	.	.	.	.	850	.	.	.	.	.	.	.	.	.	860	.	.	.	.	.	.	.	.	.	870	.	.	.	.	.	.	.	.	.	880	.	.	.	.	.	.	.	.	.	890	.	.	.	.	.	.	.	.	.	900	.	.	.	.	.	.	.	.	.	910
Sequence	N	F	S	P	Y	Q	P	P	V	Y	N	Q	K	H	R	N	P	G	G	R	T	G	I	R	G	K	G	A	L	N	T	L	G	P	N	H	I	L	H	P	I	F	T	R	W	R	D	K	V	L	E	F	L	A	V	W	R	W	A	L	L	G	G	P	A	L	A	Q	V	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			S							S							T	T							S		T	T	S	S	S	S																							B				B
	.	.	.	.	.	.	.	.	.	920	.	.	.	.	.	.	.	.	.	930	.	.	.	.	.	.	.	.	.	940	.	.	.	.	.	.	.	.	.	950	.	.	.	.	.	.	.	.	.	960	.	.	.	.	.	.	.	.	.	970	.	.	.	.	.	.	.	.	.	980
Sequence	E	R	I	L	G	K	K	L	N	E	G	E	E	V	Y	K	G	Y	V	D	D	S	R	N	T	D	N	A	W	V	E	T	S	I	I	T	L	H	C	D	K	N	T	M	A	D	L	N	H	M	V	E	L	Q	W	R	E	V	S	S	D	A	C	R	C	S	Y	Q	R	E
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)								T														T	T			S	S																		T	T	T	S	S											S	S	S		S	S
	.	.	.	.	.	.
Sequence	A	L	R	Q	I	A
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)