PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c5c8eC_

Fold library id	PDB Header	Molecule	Title
c5c8eC_	PDB header: transcription regulator/dna	Chain: C: PDB Molecule: light-dependent transcriptional regulator carh;	PDBTitle: crystal structure of thermus thermophilus carh bound to2 adenosylcobalamin and a 26-bp dna segment

Links to external resources
Added to library: Sat Oct 3 08:24:07 2015

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence H M T S S G V Y T I A E V E A M T G L S A E V L R Q W E R R Y G F P K P R R T P G G H R L Y S A E D V E A L K T I K R W L E E G A T P K A A

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S
T T T
T
S
S S S

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence I R R Y L A Q E V R P E D L G T G L L E A L L R G D L A G A E A L F R R G L R F W G P E G V L E H L L L P V L R E V G E A W H R G E I G V A

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S
T T T T
T T S S

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence E E H L A S T F L R A R L Q E L L D L A G F P P G P P V L V T T P P G E R H E I G A M L A A Y H L R R K G V P A L Y L G P D T P L P D L R A

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S
S S S
T T
T T T
S

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240 . . . . . . . . . 250 . . . . . . . . . 260 . . . . . . . . . 270 . . . . . . . . .

Sequence L A R R L G A G A V V L S A V L S E P L R A L P D G A L K D L A P R V F L G G Q G A G P E E A R R L G A E Y M E D L K G L A E A L W L P R

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T
S
S S S T S
T T T T T T S S S S T T
T
S S

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	H	M	T	S	S	G	V	Y	T	I	A	E	V	E	A	M	T	G	L	S	A	E	V	L	R	Q	W	E	R	R	Y	G	F	P	K	P	R	R	T	P	G	G	H	R	L	Y	S	A	E	D	V	E	A	L	K	T	I	K	R	W	L	E	E	G	A	T	P	K	A	A
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)				S	S										T	T	T														T			S						S	S	S
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	I	R	R	Y	L	A	Q	E	V	R	P	E	D	L	G	T	G	L	L	E	A	L	L	R	G	D	L	A	G	A	E	A	L	F	R	R	G	L	R	F	W	G	P	E	G	V	L	E	H	L	L	L	P	V	L	R	E	V	G	E	A	W	H	R	G	E	I	G	V	A
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)								S			T	T												T	T																									T															T	S	S
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	E	E	H	L	A	S	T	F	L	R	A	R	L	Q	E	L	L	D	L	A	G	F	P	P	G	P	P	V	L	V	T	T	P	P	G	E	R	H	E	I	G	A	M	L	A	A	Y	H	L	R	R	K	G	V	P	A	L	Y	L	G	P	D	T	P	L	P	D	L	R	A
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																				S				S	S	S								T	T																T	T	T								S
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.
Sequence	L	A	R	R	L	G	A	G	A	V	V	L	S	A	V	L	S	E	P	L	R	A	L	P	D	G	A	L	K	D	L	A	P	R	V	F	L	G	G	Q	G	A	G	P	E	E	A	R	R	L	G	A	E	Y	M	E	D	L	K	G	L	A	E	A	L	W	L	P	R
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)						T		S							S	S	S					T	S		T	T	T	T	T	T	S	S	S						S	T	T										T							S									S