PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c5btrB_

Fold library id	PDB Header	Molecule	Title
c5btrB_	PDB header: hydrolase/substrate	Chain: B: PDB Molecule: nad-dependent protein deacetylase sirtuin-1,nad-dependent	PDBTitle: crystal structure of sirt1 in complex with resveratrol and an amc-2 containing peptide

Links to external resources
Added to library: Sat Jul 11 08:22:36 2015

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence S R D N L L F G D E I I T N G S D W T P R P R I G P Y T F V Q Q H L M I G T D P R T I L K D L L P E T I P P P E L D D M T L W Q I V I N I L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S S
S
S S
T
S T T
T T

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence S E P P K R K K R K D I N T I E D A V K L L Q E S K K I I V L T G A G V S V S S G I P D F R S R D G I Y A R L A V D F P D L P D P Q A M F D

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S
T T
S
S S
G G G S T T T T
S S S S S S
T T
S G G G G G B

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence I E Y F R K D P R P F F K F A K E I Y P G Q F Q P S L C H K F I A L S D K E G K L L R N Y T Q N I D T L E Q V A G I Q R I I Q C H G S F A T

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T S
T T
S
T T
S S T T

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240 . . . . . . . . . 250 . . . . . . . . . 260 . . . . . . . . . 270 . . . . . . . . . 280

Sequence A S C L I C K Y K V D C E A V R G D I F N Q V V P R C P R C P A D E P L A I M K P E I V F F G E N L P E Q F H R A M K Y D K D E V D L L I V

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S S S
T T
B
S S S
T T
T T
B
B T S
T T T
S

. . . . . . . . . 290 . . . . . . . . . 300 . . . . . . . . . 310 . . . . . . . . . 320 . . . . . . . . . 330 . . . . . . . . . 340 . . . . . . . . . 350

Sequence I G S S L K V R P V A L I P S S I P H E V P Q I L I N R E P L P H L H F D V E L L G D C D V I I N E L C H R L G G E Y A K L S S N I T E Q Y

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S
S T T G G G S
T T S
S S
T T
S S
T T
S S

. . . . . . . . . 360 . . . . . .

Sequence L F L P P N R Y I F H G A E V Y

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T T
T T

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	S	R	D	N	L	L	F	G	D	E	I	I	T	N	G	S	D	W	T	P	R	P	R	I	G	P	Y	T	F	V	Q	Q	H	L	M	I	G	T	D	P	R	T	I	L	K	D	L	L	P	E	T	I	P	P	P	E	L	D	D	M	T	L	W	Q	I	V	I	N	I	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			S	S	S			S										S	S																		T											S	T	T					T	T
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	S	E	P	P	K	R	K	K	R	K	D	I	N	T	I	E	D	A	V	K	L	L	Q	E	S	K	K	I	I	V	L	T	G	A	G	V	S	V	S	S	G	I	P	D	F	R	S	R	D	G	I	Y	A	R	L	A	V	D	F	P	D	L	P	D	P	Q	A	M	F	D
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)		S								T	T			S												S	S							G	G	G	S	T	T	T	T				S	S	S	S	S	S										T	T			S	G	G	G	G	G	B
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	I	E	Y	F	R	K	D	P	R	P	F	F	K	F	A	K	E	I	Y	P	G	Q	F	Q	P	S	L	C	H	K	F	I	A	L	S	D	K	E	G	K	L	L	R	N	Y	T	Q	N	I	D	T	L	E	Q	V	A	G	I	Q	R	I	I	Q	C	H	G	S	F	A	T
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																				T	T	S																T	T											S						T	T		S	S				T	T
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280
Sequence	A	S	C	L	I	C	K	Y	K	V	D	C	E	A	V	R	G	D	I	F	N	Q	V	V	P	R	C	P	R	C	P	A	D	E	P	L	A	I	M	K	P	E	I	V	F	F	G	E	N	L	P	E	Q	F	H	R	A	M	K	Y	D	K	D	E	V	D	L	L	I	V
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)				S	S	S															T	T				B		S	S	S		T	T		T	T		B								B	T	S														T	T	T		S
	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350
Sequence	I	G	S	S	L	K	V	R	P	V	A	L	I	P	S	S	I	P	H	E	V	P	Q	I	L	I	N	R	E	P	L	P	H	L	H	F	D	V	E	L	L	G	D	C	D	V	I	I	N	E	L	C	H	R	L	G	G	E	Y	A	K	L	S	S	N	I	T	E	Q	Y
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)		S					S	T	T	G	G	G					S		T	T	S							S	S			T	T				S					S																			T	T							S	S
	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.
Sequence	L	F	L	P	P	N	R	Y	I	F	H	G	A	E	V	Y
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)				T	T	T					T	T