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 Protein Homology/analogY Recognition Engine V 2.0


 

Fold library entry viewer: c5a63A_

Fold library idPDB HeaderMoleculeTitle
c5a63A_PDB header: hydrolaseChain: A: PDB Molecule: nicastrin;PDBTitle: cryo-em structure of the human gamma-secretase complex at 3.42 angstrom resolution.


Added to library: Sat Aug 8 08:30:13 2015
 
Links to external resources


 1........10.........20.........30.........40.........50.........60.........70
Sequence NSVERKIYIPLNKTAPCVRLLNATHQIGCQSSISGDTGVIHVVEKEEDLQWVLTDGPNPPYMVLLESKHF
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Known secondary structure (DSSP)

S



SS

B
SS

SSTS
SSSSBTTT
 .........80.........90.........100.........110.........120.........130.........140
Sequence TRDLMEKLKGRTSRIAGLAVSLTKPSPASGFSPSVQCPNDGFGVYSNSYGPEFAHCREIQWNSLGNGLAY
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Known secondary structure (DSSP)
TTTT




SS

SS



S
SSTTTTTSS

SSS
GGGTT
SS

SSTT



TT
 .........150.........160.........170.........180.........190.........200.........210
Sequence EDFSFPIFLLEDENETKVIKQCYQDHNLSQNGSAPTFPLCAMQLFSHMHAVISTATCMRRSSIQSTFSIN
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Known secondary structure (DSSP) SSS

S


BTTTB

S
BBS

S
TSSS
 .........220.........230.........240.........250.........260.........270.........280
Sequence PEIVCDPLSDYNVWSMLKPINTTGTLKPDDRVVVAATRLDSRSFFWNVAPGAESAVASFVTQLAAAEALQ
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Known secondary structure (DSSP)





SS



SS


SSS





SSSS



TTTT
 .........290.........300.........310.........320.........330.........340.........350
Sequence KAPDVTTLPRNVMFVFFQGETFDYIGSSRMVYDMEKGKFPVQLENVDSFVELGQVALRTSLELWMHTDPV
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Known secondary structure (DSSP) SSTTSS
SSTTTTTTTTTT
SSS
TTTS
S

TTS

 .........360.........370.........380.........390.........400.........410.........420
Sequence SQKNESVRNQVEDLLATLEKSGAGVPAVILRRPNQSQPLPPSSLQRFLRARNISGVVLADHSGAFHNKYY
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Known secondary structure (DSSP) ST
TTS

SS




S
S


S
SSS
S
SST
 .........430.........440.........450.........460.........470.........480.........490
Sequence QSIYDTAENINVSYPEWLSPEEDLNFVTDTAKALADVATVLGRALYELAGGTNFSDTVQADPQTVTRLLY
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Known secondary structure (DSSP) TSTT
ST



SS

ST


T

S
TTT



 .........500.........510.........520.........530.........540.........550.........560
Sequence GFLIKANNSWFQSILRQDLRSYLGDGPLQHYIAVSSPTNTTYVVQYALANLTGTVVNLTREQCQDPSKVP
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Known secondary structure (DSSP) T
SSSSTTGGGS
TTGGGG

SS






SSSS
S



TTTSS
 .........570.........580.........590.........600.........610.........620.........630
Sequence SENKDLYEYSWVQGPLHSNETDRLPRCVRSTARLARALSPAFELSQWSSTEYSTWTESRWKDIRARIFLI
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Known secondary structure (DSSP) SS
TTT




BTTTTB







TT

S
SSS



BS

 .........640.........650.........660.....
Sequence ASKELELITLTVGFGILIFSLIVTYCINAKADVLF
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Known secondary structure (DSSP)
T


Download:PDB structure FASTA sequence

Hidden Markov model

Image coloured by rainbow N → C terminus
Interactive 3D view in JSmol


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Accessibility Statement
Please cite: The Phyre2 web portal for protein modeling, prediction and analysis
Kelley LA et al. Nature Protocols 10, 845-858 (2015) [paper] [Citation link]
 
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