PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c4yxpA_

Fold library id	PDB Header	Molecule	Title
c4yxpA_	PDB header: viral protein	Chain: A: PDB Molecule: mrna export factor;	PDBTitle: the structure of the folded domain of the signature multifunctional2 protein icp27 from herpes simplex virus-1 reveals an intertwined3 dimer.

Links to external resources
Added to library: Sat Jun 20 08:39:34 2015

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence A D T I D A T T R L V L R S I S E R A A V D R I S E S F G R S A Q V M H D P F G G Q P F P A A N S P W A P V L A G Q F D A E T R R V S W E T

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T
T T S T T T T
T T
T T S
T T T T

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence L V A H G P S L Y R T F A G N P R A A S T A K A M R D C V L R Q E N F I E A L A S A D E T L A W C K M C I H H N L P L R P Q D P I I G T T A

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T
B
T T S T

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence A V L D N L A T R L R P F L Q C Y L K A R G L C G L D E L C S R R R L A D I K D I A S F V F V I L A R L A N R V E R G V A E I D Y A T L G V

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T
G G G
S T
S S B
G G G G T

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240 . . . . . . . . . 250 . . . . . . . . . 260 . . . . . . . .

Sequence G V G E K M H F Y L P G A C M A G L I E I L D T H R Q E C S S R V C E L T A S H I V A P P Y V H G K Y F Y C N S L F

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T
T T
T T G G G T
S
S
S
S

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	A	D	T	I	D	A	T	T	R	L	V	L	R	S	I	S	E	R	A	A	V	D	R	I	S	E	S	F	G	R	S	A	Q	V	M	H	D	P	F	G	G	Q	P	F	P	A	A	N	S	P	W	A	P	V	L	A	G	Q	F	D	A	E	T	R	R	V	S	W	E	T
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)														T																					T	T	S	T	T	T	T						T	T		T	T					S					T	T	T	T
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	L	V	A	H	G	P	S	L	Y	R	T	F	A	G	N	P	R	A	A	S	T	A	K	A	M	R	D	C	V	L	R	Q	E	N	F	I	E	A	L	A	S	A	D	E	T	L	A	W	C	K	M	C	I	H	H	N	L	P	L	R	P	Q	D	P	I	I	G	T	T	A
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																																																							T	T			B		T	T	S					T
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	A	V	L	D	N	L	A	T	R	L	R	P	F	L	Q	C	Y	L	K	A	R	G	L	C	G	L	D	E	L	C	S	R	R	R	L	A	D	I	K	D	I	A	S	F	V	F	V	I	L	A	R	L	A	N	R	V	E	R	G	V	A	E	I	D	Y	A	T	L	G	V
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																						T													G	G	G			S																			T		S	S	B		G	G	G	G	T
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.
Sequence	G	V	G	E	K	M	H	F	Y	L	P	G	A	C	M	A	G	L	I	E	I	L	D	T	H	R	Q	E	C	S	S	R	V	C	E	L	T	A	S	H	I	V	A	P	P	Y	V	H	G	K	Y	F	Y	C	N	S	L	F
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)		T	T				T	T			T	T													G	G	G	T															S		S			S								S