PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c4yhaF_

Fold library id	PDB Header	Molecule	Title
c4yhaF_	PDB header: lyase	Chain: F: PDB Molecule: alpha-carbonic anhydrase;	PDBTitle: crystal structure of the complex of helicobacter pylori -alpha2 carbonic anhydrase with methazolamide

Links to external resources
Added to library: Sat Jul 4 08:20:05 2015

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence W D Y K N K E N G P H R W D K L H K D F E V C K S G K S Q S P I N I E H Y Y H T Q D K A D L Q F K Y A A S K P K A V F F T H H T L K A S F E

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S S S T T S G G G
G G G G
S S
S
S
S
S T T

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence P T N H I N Y R G H D Y V L D N V H F H A P M E F L I N N K T R P L S A H F V H K D A K G R L L V L A I G F E E E N P N L D P I L E G I Q K

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T S T T S S
S
T T B
S
T T
G G G T T T T T S S S

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence K D A F L P K S I N Y Y H F N G S L T A P P C T E G V A W F V I E E P L E V S A K Q L A E I K K R M K N S P N Q R P V Q P D Y N T V I I K S

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S
S
S S T T
T T T T T T S S T T T T T

. . . . .

Sequence S A E T R

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	W	D	Y	K	N	K	E	N	G	P	H	R	W	D	K	L	H	K	D	F	E	V	C	K	S	G	K	S	Q	S	P	I	N	I	E	H	Y	Y	H	T	Q	D	K	A	D	L	Q	F	K	Y	A	A	S	K	P	K	A	V	F	F	T	H	H	T	L	K	A	S	F	E
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			S	S	S	S	T	T	S	G	G	G						G	G	G	G						S	S		S											S				S											S						T	T
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	P	T	N	H	I	N	Y	R	G	H	D	Y	V	L	D	N	V	H	F	H	A	P	M	E	F	L	I	N	N	K	T	R	P	L	S	A	H	F	V	H	K	D	A	K	G	R	L	L	V	L	A	I	G	F	E	E	E	N	P	N	L	D	P	I	L	E	G	I	Q	K
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T	T	S					T	T												S	S		S				T	T	B			S										T	T															G	G	G	T	T	T	T	T	S	S	S
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	K	D	A	F	L	P	K	S	I	N	Y	Y	H	F	N	G	S	L	T	A	P	P	C	T	E	G	V	A	W	F	V	I	E	E	P	L	E	V	S	A	K	Q	L	A	E	I	K	K	R	M	K	N	S	P	N	Q	R	P	V	Q	P	D	Y	N	T	V	I	I	K	S
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)				S	S		S												S	S	T	T																		T	T	T	T	T	T	S	S	T	T	T	T	T
	.	.	.	.	.
Sequence	S	A	E	T	R
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)