PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c4xtiA_

Fold library id	PDB Header	Molecule	Title
c4xtiA_	PDB header: oxidoreductase	Chain: A: PDB Molecule: inosine-5'-monophosphate dehydrogenase,inosine-5'-	PDBTitle: structure of imp dehydrogenase of ashbya gossypii with imp bound to2 the active site

Links to external resources
Added to library: Sat Jul 25 08:27:26 2015

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence Y R D A A T A L E H L A T Y A E K D G L S V E Q L M G G L T Y N D F L V L P G K I D F P S S E V V L S S R L T K K I T L N A P F V S S P M D

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
G G G G G G S S S
S S B
G G G
S
G G G
B
S S S S
S S
S
T

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence T V T E A D M A I H M A L L G G I G I I H H N C T A E E Q A E M V R R V K K Y L A S K S A D T K Q L L C G A A I G T I D A D R Q R L A M L V

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T
S T T
S S
T
B
T T T
B
S S T

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence E A G L D V V V L D S S Q G N S V F Q I N M I K W I K E T F P D L Q V I A G N V V T R E Q A A S L I H A G A D G L R I G M G S G S I C I T Q

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T
S S
S
S S S
S T
S
S S
S T T B

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240 . . . . . . . . . 250 . . . . . . . . . 260 . . . . . . . . . 270 . . . . . . . . . 280

Sequence E V M A C G R P Q G T A V Y N V T Q F A N Q F G V P C I A D G G V Q N I G H I T K A I A L G A S T V M M G G M L A G T T E S P G E Y F F R K

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
G G G T
S
S T T
S S T T T T T B T T S S S

. . . . . . . . . 290 . . . . . . . . . 300 . . . . . . . . . 310 . . . . . . . . . 320 . . . . . . . . . 330 . . . . . . . . . 340 . . . . . . . . . 350

Sequence R L K T Y R G M G S I D A M Q K L V A Q G V T G S V I D K G S I K K Y I P Y L Y N G L Q H S C Q D I G V R S L V E F R E K V D S G S V R F E

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T S T
B
B
T
S B T
S

. . . . . . . . . 360 . . . . . . . . . 370 . . .

Sequence F R T P S A Q L E G G V H N L H S Y E K R L F

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S
S
S

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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Phyre2 is part of Genome3D

	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	Y	R	D	A	A	T	A	L	E	H	L	A	T	Y	A	E	K	D	G	L	S	V	E	Q	L	M	G	G	L	T	Y	N	D	F	L	V	L	P	G	K	I	D	F	P	S	S	E	V	V	L	S	S	R	L	T	K	K	I	T	L	N	A	P	F	V	S	S	P	M	D
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)				G	G	G					G	G	G	S	S	S		S	S	B											G	G	G										S		G	G	G		B					S	S	S	S				S	S						S		T
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	T	V	T	E	A	D	M	A	I	H	M	A	L	L	G	G	I	G	I	I	H	H	N	C	T	A	E	E	Q	A	E	M	V	R	R	V	K	K	Y	L	A	S	K	S	A	D	T	K	Q	L	L	C	G	A	A	I	G	T	I	D	A	D	R	Q	R	L	A	M	L	V
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T	T		S										T	T								S	S														T					B		T	T	T			B								S	S	T
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	E	A	G	L	D	V	V	V	L	D	S	S	Q	G	N	S	V	F	Q	I	N	M	I	K	W	I	K	E	T	F	P	D	L	Q	V	I	A	G	N	V	V	T	R	E	Q	A	A	S	L	I	H	A	G	A	D	G	L	R	I	G	M	G	S	G	S	I	C	I	T	Q
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)		T	T									S	S			S															S	S	S									S											T		S						S	S		S	T	T	B
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280
Sequence	E	V	M	A	C	G	R	P	Q	G	T	A	V	Y	N	V	T	Q	F	A	N	Q	F	G	V	P	C	I	A	D	G	G	V	Q	N	I	G	H	I	T	K	A	I	A	L	G	A	S	T	V	M	M	G	G	M	L	A	G	T	T	E	S	P	G	E	Y	F	F	R	K
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																					G	G	G	T							S				S										T	T		S					S	T	T	T	T	T	B	T	T	S	S	S
	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350
Sequence	R	L	K	T	Y	R	G	M	G	S	I	D	A	M	Q	K	L	V	A	Q	G	V	T	G	S	V	I	D	K	G	S	I	K	K	Y	I	P	Y	L	Y	N	G	L	Q	H	S	C	Q	D	I	G	V	R	S	L	V	E	F	R	E	K	V	D	S	G	S	V	R	F	E
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)								T	T	S					T						B									B																					T		S	B											T		S
	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.
Sequence	F	R	T	P	S	A	Q	L	E	G	G	V	H	N	L	H	S	Y	E	K	R	L	F
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)											S			S		S