PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c4xdyB_

Fold library id	PDB Header	Molecule	Title
c4xdyB_	PDB header: oxidoreductase	Chain: B: PDB Molecule: ketol-acid reductoisomerase;	PDBTitle: structure of nadh-preferring ketol-acid reductoisomerase from an2 uncultured archean

Links to external resources
Added to library: Sat Apr 25 08:20:30 2015

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence M E I L H D E D V D D S I L R D K T I A V M G Y G A Q G D A Q A N C L K D S G I N V V I G E T E I L G G N K N P S W E K A K E D G F E V L P

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
B
G G G
G G G T T
S T T
S T T
T T

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence I D K A A E K G D V V H I L L P D E V Q P A I Y E N Q I K P Q L K A G K A L C F S H G F N I C F K R I V P P E D V D V I M V A P K A P G T E

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S
S
T T T T G G G
T T
S S S T T S
T T S S S

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence E R K A Y L E G F G V P G L V A V K Q N P S G E A R E V A L A M T K A M H W T K A G I L E C T F E Q E T Y E D L F G E Q C V L C G G L V E L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T
T T S
T T G G G T
T T T

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240 . . . . . . . . . 250 . . . . . . . . . 260 . . . . . . . . . 270 . . . . . . . . . 280

Sequence M R N G F E V L V E A G Y P P E M A Y F E C V H E M K L I V D L V W Q G G I K R M A E V I S N T A E Y G M W A V G H Q I I G P E V K E K M K

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T
T S
S

. . . . . . . . . 290 . . . . . . . . . 300 . . . . . . . . . 310 . . . . . . . . . 320 . . . . . . . . . 330 .

Sequence E A L K R V E N G E F A N E W V D E Y K R G I P F L K A S R E K M G E H Q V E T V G A E I R K L F A Q

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T S T T
S T

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

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Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	M	E	I	L	H	D	E	D	V	D	D	S	I	L	R	D	K	T	I	A	V	M	G	Y	G	A	Q	G	D	A	Q	A	N	C	L	K	D	S	G	I	N	V	V	I	G	E	T	E	I	L	G	G	N	K	N	P	S	W	E	K	A	K	E	D	G	F	E	V	L	P
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)				B		G	G	G				G	G	G	T	T									S													T	T									S			T	T												T	T
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	I	D	K	A	A	E	K	G	D	V	V	H	I	L	L	P	D	E	V	Q	P	A	I	Y	E	N	Q	I	K	P	Q	L	K	A	G	K	A	L	C	F	S	H	G	F	N	I	C	F	K	R	I	V	P	P	E	D	V	D	V	I	M	V	A	P	K	A	P	G	T	E
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)									S						S		T	T	T									T	G	G	G			T	T						S	S	S					T	T	S					T	T	S								S	S
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	E	R	K	A	Y	L	E	G	F	G	V	P	G	L	V	A	V	K	Q	N	P	S	G	E	A	R	E	V	A	L	A	M	T	K	A	M	H	W	T	K	A	G	I	L	E	C	T	F	E	Q	E	T	Y	E	D	L	F	G	E	Q	C	V	L	C	G	G	L	V	E	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)							T	T													T	T	S													T	T	G	G	G	T																					T	T	T
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280
Sequence	M	R	N	G	F	E	V	L	V	E	A	G	Y	P	P	E	M	A	Y	F	E	C	V	H	E	M	K	L	I	V	D	L	V	W	Q	G	G	I	K	R	M	A	E	V	I	S	N	T	A	E	Y	G	M	W	A	V	G	H	Q	I	I	G	P	E	V	K	E	K	M	K
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)											T	T											T																						S																S
	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.
Sequence	E	A	L	K	R	V	E	N	G	E	F	A	N	E	W	V	D	E	Y	K	R	G	I	P	F	L	K	A	S	R	E	K	M	G	E	H	Q	V	E	T	V	G	A	E	I	R	K	L	F	A	Q
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)								T	S												T	T														S												T