PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c4x7qA_

Fold library id	PDB Header	Molecule	Title
c4x7qA_	PDB header: transferase/transferase inhibitor	Chain: A: PDB Molecule: serine/threonine-protein kinase pim-2;	PDBTitle: pim2 kinase in complex with compound 1s

Links to external resources
Added to library: Sat Feb 14 09:18:09 2015

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence Y R L G P L L G K G G F G T V F A G H R L Q V A I K V I P R L E V A L L W K V G H P G V I R L L D W F F M L V L E R P L P A Q D L F D Y I T

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T
S B
S S

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence E K G P L G E G P S R C F F G Q V V A A I Q H C H S R G V V H R D I K D E N I L I D L R R G C A K L I D F G S G A D G T R V Y S P P E W I S

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S
T T T
S G G G T T T T
T T
G G G S

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence R H Q Y H A L P A T V W S L G I L L Y D M V C G D I P F E R D Q E I L E A E L H F P A H V S P D C C A L I R R C L A P K P S S R P S L E E I

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S
S
S T
T T S
T
S S G G G S

. . . . . . .

Sequence L L D P W M Q

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T S
-

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	Y	R	L	G	P	L	L	G	K	G	G	F	G	T	V	F	A	G	H	R	L	Q	V	A	I	K	V	I	P	R	L	E	V	A	L	L	W	K	V	G	H	P	G	V	I	R	L	L	D	W	F	F	M	L	V	L	E	R	P	L	P	A	Q	D	L	F	D	Y	I	T
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)											T	T																															S	B																S	S
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	E	K	G	P	L	G	E	G	P	S	R	C	F	F	G	Q	V	V	A	A	I	Q	H	C	H	S	R	G	V	V	H	R	D	I	K	D	E	N	I	L	I	D	L	R	R	G	C	A	K	L	I	D	F	G	S	G	A	D	G	T	R	V	Y	S	P	P	E	W	I	S
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)				S																						T	T	T							S	G	G	G					T	T	T	T								T	T						G	G	G	S
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	R	H	Q	Y	H	A	L	P	A	T	V	W	S	L	G	I	L	L	Y	D	M	V	C	G	D	I	P	F	E	R	D	Q	E	I	L	E	A	E	L	H	F	P	A	H	V	S	P	D	C	C	A	L	I	R	R	C	L	A	P	K	P	S	S	R	P	S	L	E	E	I
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																								S	S		S			S							T						T	T	S												T		S	S	G	G	G	S
	.	.	.	.	.	.	.
Sequence	L	L	D	P	W	M	Q
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)		T	S			-