PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c4wjgY_

Fold library id	PDB Header	Molecule	Title
c4wjgY_	PDB header: endocytosis	Chain: Y: PDB Molecule: haptoglobin-hemoglobin receptor;	PDBTitle: structure of t. brucei haptoglobin-hemoglobin receptor binding to2 human haptoglobin-hemoglobin

Links to external resources
Added to library: Sat Nov 29 08:12:28 2014

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence A E G L K T K D E V E K A C H L A Q Q L K E V S I T L G V I Y R T T E R H S V Q V E A H K T A I D K H A D A V S R A V E A L T R V D V A L Q

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S T T T T T

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence R L K E L G K A N D T K A V K I I E N I T S A R E N L A L F N N E T Q A V L T A R D H V H K H R A A A L Q G W S D A K E K G D A A A E D V W

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T T T T T S S
S T T T T S

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence V L L N A A K K G N G S A D V K A A A E K C S R Y S S S S T S E T E L Q K A I D A A A N V G G L S A H K S K Y G D V L N K F K L S N A S V G

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S T T S S
S T
S S
S S
S S
T T

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240 . . . . . . . . . 250 . . . . . . . . . 260 .

Sequence A V R D T S G R G G K H M E K V N N V A K L L K D A E V S L A A A A A E I E E V K N A H E T K A Q E E

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S G G G T T T T T T

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	A	E	G	L	K	T	K	D	E	V	E	K	A	C	H	L	A	Q	Q	L	K	E	V	S	I	T	L	G	V	I	Y	R	T	T	E	R	H	S	V	Q	V	E	A	H	K	T	A	I	D	K	H	A	D	A	V	S	R	A	V	E	A	L	T	R	V	D	V	A	L	Q
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)						S																												T																					T													T	T	T
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	R	L	K	E	L	G	K	A	N	D	T	K	A	V	K	I	I	E	N	I	T	S	A	R	E	N	L	A	L	F	N	N	E	T	Q	A	V	L	T	A	R	D	H	V	H	K	H	R	A	A	A	L	Q	G	W	S	D	A	K	E	K	G	D	A	A	A	E	D	V	W
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T	T	T	T	T	T	S	S			S	T	T	T	T					S
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	V	L	L	N	A	A	K	K	G	N	G	S	A	D	V	K	A	A	A	E	K	C	S	R	Y	S	S	S	S	T	S	E	T	E	L	Q	K	A	I	D	A	A	A	N	V	G	G	L	S	A	H	K	S	K	Y	G	D	V	L	N	K	F	K	L	S	N	A	S	V	G
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)						S	T	T	S	S			S								T			S	S		S	S																S	S		T	T
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.
Sequence	A	V	R	D	T	S	G	R	G	G	K	H	M	E	K	V	N	N	V	A	K	L	L	K	D	A	E	V	S	L	A	A	A	A	A	E	I	E	E	V	K	N	A	H	E	T	K	A	Q	E	E
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																										S									G	G	G	T	T	T	T								T	T