PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c4wd7A_

Fold library id	PDB Header	Molecule	Title
c4wd7A_	PDB header: membrane protein	Chain: A: PDB Molecule: bestrophin domain protein;	PDBTitle: crystal structure of a bacterial bestrophin homolog from klebsiella2 pneumoniae by zn-sad phasing

Links to external resources
Added to library: Sat Oct 4 08:17:52 2014

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence S K I I F R L L L N V L M S I I A I I S Y Q W Y E Q L G I H L T V A P F S L L G I A I A I F L G F R N S A S Y S R F V E A R N L W G T V L I

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T G G G G T T T T

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence A E R T L V R Q L R N I L P A E H D A H R R I V S Y L V A F S W S L K H Q L R K T D P T A D L R R L L P E E R V T E I L A S S M P T N R I L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T
T
S
T S S S

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence L L A G N E I G Q L R E A G K L S D I T Y G L M D N K L D E L A H V L G G C E R L A T T P V P F A Y T L I L Q R T V Y L F C T L L P F A L V

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T S S
S

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240 . . . . . . . . . 250 . . . . . . . . . 260 . . . . . . . .

Sequence G D L H Y M T P F V S V F I S Y T F L S W D S L A E E L E D P F G T A A N D L P L N A M C N T I E R N L L D M T G Q

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) G G G S
T T S S S T T S
T T T

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	S	K	I	I	F	R	L	L	L	N	V	L	M	S	I	I	A	I	I	S	Y	Q	W	Y	E	Q	L	G	I	H	L	T	V	A	P	F	S	L	L	G	I	A	I	A	I	F	L	G	F	R	N	S	A	S	Y	S	R	F	V	E	A	R	N	L	W	G	T	V	L	I
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)		T																			G	G	G	G	T	T	T	T
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	A	E	R	T	L	V	R	Q	L	R	N	I	L	P	A	E	H	D	A	H	R	R	I	V	S	Y	L	V	A	F	S	W	S	L	K	H	Q	L	R	K	T	D	P	T	A	D	L	R	R	L	L	P	E	E	R	V	T	E	I	L	A	S	S	M	P	T	N	R	I	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)														T	T																									T											S										T	S	S	S
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	L	L	A	G	N	E	I	G	Q	L	R	E	A	G	K	L	S	D	I	T	Y	G	L	M	D	N	K	L	D	E	L	A	H	V	L	G	G	C	E	R	L	A	T	T	P	V	P	F	A	Y	T	L	I	L	Q	R	T	V	Y	L	F	C	T	L	L	P	F	A	L	V
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)													T	T	S	S																														S
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.
Sequence	G	D	L	H	Y	M	T	P	F	V	S	V	F	I	S	Y	T	F	L	S	W	D	S	L	A	E	E	L	E	D	P	F	G	T	A	A	N	D	L	P	L	N	A	M	C	N	T	I	E	R	N	L	L	D	M	T	G	Q
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)				G	G	G																							S		T	T	S	S	S	T	T	S																	T	T	T