PHYRE Protein Fold Recognition Server

Subscribe to Phyre at Google Groups

Email:

Visit Phyre at Google Groups

Protein Homology/analogY Recognition Engine V 2.0

Fold library entry viewer: c4uisB_

Fold library id	PDB Header	Molecule	Title
c4uisB_	PDB header: hydrolase	Chain: B: PDB Molecule: gamma-secretase;	PDBTitle: the cryoem structure of human gamma-secretase complex

Links to external resources
Added to library: Sat Jun 13 08:23:17 2015

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence X X X X X X X X X X X X H V I M L F V P V T L C M V V V V A T I X X X X X X X X X X X X X X X X X X X X X X X X X X X L L L F F F S F I Y L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence G E V F K T Y X X X X X X X X X X L I W N F G X X X X X X X X X X X X X R L Q Q A Y L I M I S A L M X X X X X X X X X X X X X X X X X X X X

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S
T

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence D X X X X X X X X X X X X X X X X X X X X D X X X X X X X X X X X X X X X X X X W N T T I A C F V A I L I G L C L T L L X X X X X X X X X X

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T
T
S S
S S

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240 .

Sequence X X X X X X X G L V F Y F A T D Y L V Q P F A D Q L A F H X X

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T S

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Close JSmol

Interactive 3D view in JSmol

Phyre is now FREE for commercial users!

All images and data generated by Phyre2 are free to use in any publication with acknowledgement
Accessibility Statement

Please cite: The Phyre2 web portal for protein modeling, prediction and analysis

Kelley LA et al. Nature Protocols 10, 845-858 (2015) [paper] [Citation link]

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

Disclaimer

Terms and Conditions

Structural Biology Group logo Imperial logo

BBSRC logo
Phyre2 is part of Genome3D

	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	X	X	X	X	X	X	X	X	X	X	X	X	H	V	I	M	L	F	V	P	V	T	L	C	M	V	V	V	V	A	T	I	X	X	X	X	X	X	X	X	X	X	X	X	X	X	X	X	X	X	X	X	X	X	X	X	X	X	X	L	L	L	F	F	F	S	F	I	Y	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																																	T
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	G	E	V	F	K	T	Y	X	X	X	X	X	X	X	X	X	X	L	I	W	N	F	G	X	X	X	X	X	X	X	X	X	X	X	X	X	R	L	Q	Q	A	Y	L	I	M	I	S	A	L	M	X	X	X	X	X	X	X	X	X	X	X	X	X	X	X	X	X	X	X	X
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																																			S																									T
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	D	X	X	X	X	X	X	X	X	X	X	X	X	X	X	X	X	X	X	X	X	D	X	X	X	X	X	X	X	X	X	X	X	X	X	X	X	X	X	X	W	N	T	T	I	A	C	F	V	A	I	L	I	G	L	C	L	T	L	L	X	X	X	X	X	X	X	X	X	X
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)															T				T																			S	S		S																							S
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.
Sequence	X	X	X	X	X	X	X	G	L	V	F	Y	F	A	T	D	Y	L	V	Q	P	F	A	D	Q	L	A	F	H	X	X
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																		T											S