PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.0

Fold library entry viewer: c4rhyC_

Fold library id	PDB Header	Molecule	Title
c4rhyC_	PDB header: transferase/transferase inhibitor	Chain: C: PDB Molecule: hypoxanthine-guanine phosphoribosyltransferase;	PDBTitle: crystal structures of mycobacterium tuberculosis 6-oxopurine2 phosphoribosyltransferase which is a potential target for drug3 development against this disease

Links to external resources
Added to library: Sat May 23 08:15:14 2015

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence E L Y P G D I K S V L L T A E Q I Q A R I A E L G E Q I G N D Y R E T T G Q D L L L I T V L K G A V L F V T D L A R A I P V P T Q F E F M A

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S T T T
T T T T S S S

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence V S S Y S G V V R I L K D L D R D I H G R D V L I V E D V V D S G L T L S W L S R N L T S R N P R S L R V C T L L R K P D A V H A N V E I A

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S
T T
S S S T T
S
G G G T T
S S
S

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . .

Sequence Y V G F D I P N D F V V G Y G L D Y D E R Y R D L S Y I G T L D P R V Y Q

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S
B T T B
B T T B S T T
S S
T T T T

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

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Please cite: The Phyre2 web portal for protein modeling, prediction and analysis

Kelley LA et al. Nature Protocols 10, 845-858 (2015) [paper] [Citation link]

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	E	L	Y	P	G	D	I	K	S	V	L	L	T	A	E	Q	I	Q	A	R	I	A	E	L	G	E	Q	I	G	N	D	Y	R	E	T	T	G	Q	D	L	L	L	I	T	V	L	K	G	A	V	L	F	V	T	D	L	A	R	A	I	P	V	P	T	Q	F	E	F	M	A
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			S	T	T	T																																								T	T	T	T											S	S	S
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	V	S	S	Y	S	G	V	V	R	I	L	K	D	L	D	R	D	I	H	G	R	D	V	L	I	V	E	D	V	V	D	S	G	L	T	L	S	W	L	S	R	N	L	T	S	R	N	P	R	S	L	R	V	C	T	L	L	R	K	P	D	A	V	H	A	N	V	E	I	A
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)															S	S			T	T											S	S	S												T	T			S											G	G	G	T	T		S	S			S
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.
Sequence	Y	V	G	F	D	I	P	N	D	F	V	V	G	Y	G	L	D	Y	D	E	R	Y	R	D	L	S	Y	I	G	T	L	D	P	R	V	Y	Q
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)								S					B	T	T	B		B	T	T	B	S	T	T		S	S						T	T	T	T