PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c4otpA_

Fold library id	PDB Header	Molecule	Title
c4otpA_	PDB header: transferase	Chain: A: PDB Molecule: serine/threonine-protein kinase rio1;	PDBTitle: crystal structure of the catalytic domain of the human riok1 atypical2 protein kinase in complex with adp/mg2+

Links to external resources
Added to library: Sat Jul 5 08:36:37 2014

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence D P R T R X I L F K X L T R G I I T E I N G C I S T G K E A N V Y H A S T A N G E S R A I K I Y K K T W A E K E X R N L I R L N T A E I P C

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T T T S S
S S
T T S
T T

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence P E P I M L R S H V L V X S F I G K D D X P A P L L K N V Q L S E S K A R E L Y L Q V I Q Y X R R X Y Q D A R L V H A D L S E F N X L Y H G

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T
T T
B G G G
T S
S S
S G G G T

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence G G V Y I I V S Q S V E H D H P H A L E F L R K D C A N V N D F F X R H S V A V X T V R E L F E F V T D P S I T H E N M D A Y L S K A X E I

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T
S
T T
T T T T S
S
T T S

. . . . . . . . . 220 . . . . . . . . . 230 . . . . .

Sequence A S Q R T K E E R S S Q D H V D E E V F K R A Y I

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	D	P	R	T	R	X	I	L	F	K	X	L	T	R	G	I	I	T	E	I	N	G	C	I	S	T	G	K	E	A	N	V	Y	H	A	S	T	A	N	G	E	S	R	A	I	K	I	Y	K	K	T	W	A	E	K	E	X	R	N	L	I	R	L	N	T	A	E	I	P	C
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)		T	T											T	T	S	S											S	S									T	T	S																										T	T
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	P	E	P	I	M	L	R	S	H	V	L	V	X	S	F	I	G	K	D	D	X	P	A	P	L	L	K	N	V	Q	L	S	E	S	K	A	R	E	L	Y	L	Q	V	I	Q	Y	X	R	R	X	Y	Q	D	A	R	L	V	H	A	D	L	S	E	F	N	X	L	Y	H	G
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)								T	T										T	T					B	G	G	G																									T	S					S	S		S	G	G	G					T
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	G	G	V	Y	I	I	V	S	Q	S	V	E	H	D	H	P	H	A	L	E	F	L	R	K	D	C	A	N	V	N	D	F	F	X	R	H	S	V	A	V	X	T	V	R	E	L	F	E	F	V	T	D	P	S	I	T	H	E	N	M	D	A	Y	L	S	K	A	X	E	I
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T								S				T	T		T	T																		T	T	S																S				T	T	S
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.
Sequence	A	S	Q	R	T	K	E	E	R	S	S	Q	D	H	V	D	E	E	V	F	K	R	A	Y	I
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)				S