PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c4or2A_

Fold library id	PDB Header	Molecule	Title
c4or2A_	PDB header: signaling protein	Chain: A: PDB Molecule: soluble cytochrome b562, metabotropic glutamate receptor 1;	PDBTitle: human class c g protein-coupled metabotropic glutamate receptor 1 in2 complex with a negative allosteric modulator

Links to external resources
Added to library: Sat Mar 22 08:18:25 2014

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence D L E D N W E T L N D N L K V I E K A D N A A Q V K D A L T K M R A A A L D A Q K A T P P K L E D K S P D S P E M K D F R H G F D I L V G Q

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T
S S S S
G G G T T S
T T S

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence I D D A L K L A N E G K V K E A Q A A A E Q L K T T R N A Y I Q K Y L I P V R Y L E W S N I E S I I A I A F S C L G I L V T L F V T L I F V

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T
T G G G T S
T T S

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence L Y R D T P V V K S S S R E L C Y I I L A G I F L G Y V C P F T L I A K P T T T S C Y L Q R L L V G L S S A M C Y S A L V T K T N R I A R I

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T S S S S S
S

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240 . . . . . . . . . 250 . . . . . . . . . 260 . . . . . . . . . 270 . . . . . . . . . 280

Sequence L A R K P R F M S A W A Q V I I A S I L I S V Q L T L V V T L I I M E P P M P I L S Y P S I K E V Y L I C N T S N L G V V A P L G Y N G L L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S
S S
S S S

. . . . . . . . . 290 . . . . . . . . . 300 . . . . . . . . . 310 . . . . . . . . . 320 . . . . . . . . . 330 . . . . . . . . . 340 . . . . . . . . . 350

Sequence I M S C T Y Y A F K T R N V P A N F N E A K Y I A F T M Y T T C I I W L A F V P I Y F G S N Y K I I T T C F A V S L S V T V A L G C M F T P

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T T
S S

. . . . . . . . . 360

Sequence K M Y I I I A K P E

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

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Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	D	L	E	D	N	W	E	T	L	N	D	N	L	K	V	I	E	K	A	D	N	A	A	Q	V	K	D	A	L	T	K	M	R	A	A	A	L	D	A	Q	K	A	T	P	P	K	L	E	D	K	S	P	D	S	P	E	M	K	D	F	R	H	G	F	D	I	L	V	G	Q
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																		T			S	S																			S	S			G	G	G	T	T	S		T	T	S
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	I	D	D	A	L	K	L	A	N	E	G	K	V	K	E	A	Q	A	A	A	E	Q	L	K	T	T	R	N	A	Y	I	Q	K	Y	L	I	P	V	R	Y	L	E	W	S	N	I	E	S	I	I	A	I	A	F	S	C	L	G	I	L	V	T	L	F	V	T	L	I	F	V
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)											T																				T	G	G	G	T	S							T	T	S
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	L	Y	R	D	T	P	V	V	K	S	S	S	R	E	L	C	Y	I	I	L	A	G	I	F	L	G	Y	V	C	P	F	T	L	I	A	K	P	T	T	T	S	C	Y	L	Q	R	L	L	V	G	L	S	S	A	M	C	Y	S	A	L	V	T	K	T	N	R	I	A	R	I
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)		T	S	S	S					S	S																								S
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280
Sequence	L	A	R	K	P	R	F	M	S	A	W	A	Q	V	I	I	A	S	I	L	I	S	V	Q	L	T	L	V	V	T	L	I	I	M	E	P	P	M	P	I	L	S	Y	P	S	I	K	E	V	Y	L	I	C	N	T	S	N	L	G	V	V	A	P	L	G	Y	N	G	L	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)						S	S		S																										S										S	S	S
	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350
Sequence	I	M	S	C	T	Y	Y	A	F	K	T	R	N	V	P	A	N	F	N	E	A	K	Y	I	A	F	T	M	Y	T	T	C	I	I	W	L	A	F	V	P	I	Y	F	G	S	N	Y	K	I	I	T	T	C	F	A	V	S	L	S	V	T	V	A	L	G	C	M	F	T	P
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)											T	T	T																																S	S
	.	.	.	.	.	.	.	.	.	360
Sequence	K	M	Y	I	I	I	A	K	P	E
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)							T