PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c4opxD_

Fold library id	PDB Header	Molecule	Title
c4opxD_	PDB header: transferase/dna/transferase inhibitor	Chain: D: PDB Molecule: poly [adp-ribose] polymerase 1;	PDBTitle: structure of human parp-1 bound to a dna double strand break in2 complex with (2r)-5-fluoro-2-methyl-2,3-dihydro-1-benzofuran-7-3 carboxamide

Links to external resources
Added to library: Sat Jul 5 08:25:01 2014

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence D K L Y R V E Y A K S G R A S C K K C S E S I P K D S L R M A I M V Q S P M F D G K V P H W Y H F S C F W K V G H S I R H P D V E V D G F S

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S
S
T T
B
T T T
B
T T
S S S S S T T G G G T T T
S
T T T

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence E L R W D D Q Q K V K K T A E A S K K E K D K D S K L E K A L K A Q N D L I W N I K D E L K K V C S T N D L K E L L I F N K Q Q V P S G E S

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T S
T T
S S

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence A I L D R V A D G M V F G A L L P C E E C S G Q L V F K S D A Y Y C T G D V T A W T K C M V K T Q T P N R K E W V T P K E F R E I S Y L K K

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T
S S S
T T
S
S S S S S
S S
S
T T T T

. . . . . . . . . 220 . .

Sequence L K V K K Q D R I F P P

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	D	K	L	Y	R	V	E	Y	A	K	S	G	R	A	S	C	K	K	C	S	E	S	I	P	K	D	S	L	R	M	A	I	M	V	Q	S	P	M	F	D	G	K	V	P	H	W	Y	H	F	S	C	F	W	K	V	G	H	S	I	R	H	P	D	V	E	V	D	G	F	S
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			S							S		T	T		B		T	T	T			B			T	T											S	S	S	S	S								T	T	G	G	G	T	T	T				S								T	T	T
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	E	L	R	W	D	D	Q	Q	K	V	K	K	T	A	E	A	S	K	K	E	K	D	K	D	S	K	L	E	K	A	L	K	A	Q	N	D	L	I	W	N	I	K	D	E	L	K	K	V	C	S	T	N	D	L	K	E	L	L	I	F	N	K	Q	Q	V	P	S	G	E	S
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T	S																																																											T	T					S	S
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	A	I	L	D	R	V	A	D	G	M	V	F	G	A	L	L	P	C	E	E	C	S	G	Q	L	V	F	K	S	D	A	Y	Y	C	T	G	D	V	T	A	W	T	K	C	M	V	K	T	Q	T	P	N	R	K	E	W	V	T	P	K	E	F	R	E	I	S	Y	L	K	K
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)												T							S	S	S								T	T						S		S	S	S	S	S							S	S										S			T	T					T	T
	.	.	.	.	.	.	.	.	.	220	.	.
Sequence	L	K	V	K	K	Q	D	R	I	F	P	P
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T	T