PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c4ndkA_

Fold library id	PDB Header	Molecule	Title
c4ndkA_	PDB header: fluorescent protein, de novo protein	Chain: A: PDB Molecule: e23p-yfp, chimeric construct;	PDBTitle: crystal structure of a computational designed engrailed homeodomain2 variant fused with yfp

Links to external resources
Added to library: Sat Nov 8 08:21:41 2014

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence Q K K A L D L A F Y F D R R L T P E W R R Y L S Q R L G L N E E Q I E R W F R R K E Q Q I M V S K G E E L F T G V V P I L V E L D G D V N G

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T
S
T S S
T T

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence H K F S V S G E G E G D A T Y G K L T L K L I C T T G K L P V P F P T L V T T L L Q C F A R Y P D H M K Q H D F F K S A M P E G Y V Q E R T

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) G G G T T T S S
S S
G G G G T T T
G G G
B
G G G G G G
T T T T

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence I F F K D D G N Y K T R A E V K F E G D T L V N R I E L K G I D F K E D G N I L G H K L E Y N Y N S H N V Y I T A D K Q K N G I K A N F K I

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T S
T T S
T T S T T T T T
B
S
G G G T

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240 . . . . . . . . . 250 . . . . . . . . . 260 . . . . . . . . . 270 .

Sequence R H N I E D G G V Q L A D H Y Q Q N T P I G D G P V L L P D N H Y L S Y Q S K L S K D P N E K R D H M V L L E F V T A A G

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) B T T S
S S S S
S
T T
S S

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	Q	K	K	A	L	D	L	A	F	Y	F	D	R	R	L	T	P	E	W	R	R	Y	L	S	Q	R	L	G	L	N	E	E	Q	I	E	R	W	F	R	R	K	E	Q	Q	I	M	V	S	K	G	E	E	L	F	T	G	V	V	P	I	L	V	E	L	D	G	D	V	N	G
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			T																									S																										T	S	S													T	T
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	H	K	F	S	V	S	G	E	G	E	G	D	A	T	Y	G	K	L	T	L	K	L	I	C	T	T	G	K	L	P	V	P	F	P	T	L	V	T	T	L	L	Q	C	F	A	R	Y	P	D	H	M	K	Q	H	D	F	F	K	S	A	M	P	E	G	Y	V	Q	E	R	T
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)													G	G	G	T									T	T	S	S		S	S		G	G	G	G	T	T	T			G	G	G		B			G	G	G	G	G	G						T	T	T	T
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	I	F	F	K	D	D	G	N	Y	K	T	R	A	E	V	K	F	E	G	D	T	L	V	N	R	I	E	L	K	G	I	D	F	K	E	D	G	N	I	L	G	H	K	L	E	Y	N	Y	N	S	H	N	V	Y	I	T	A	D	K	Q	K	N	G	I	K	A	N	F	K	I
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)				T	T	S													T	T												S			T	T	S	T	T	T	T	T		B		S													G	G	G	T
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.
Sequence	R	H	N	I	E	D	G	G	V	Q	L	A	D	H	Y	Q	Q	N	T	P	I	G	D	G	P	V	L	L	P	D	N	H	Y	L	S	Y	Q	S	K	L	S	K	D	P	N	E	K	R	D	H	M	V	L	L	E	F	V	T	A	A	G
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)				B	T	T	S														S	S	S	S							S													T	T			S	S