PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c4n7vB_

Fold library id	PDB Header	Molecule	Title
c4n7vB_	PDB header: cell cycle	Chain: B: PDB Molecule: serine/threonine-protein kinase plk4;	PDBTitle: crystal structure of human plk4 cryptic polo box (cpb) in complex with2 a cep152 n-terminal fragment

Links to external resources
Added to library: Sat Jul 5 08:23:50 2014

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence T L R S I T S P L V A H R L K P I R Q K T K K A V V S I L D S E E V C V E L V K E Y A S Q E Y V K E V L Q I S S D G N T I T I Y Y P N G G R

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
G G G G S
T T
S S
T T S
T T
T T S S
G G G G T

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence G F P L A D R P P S P T D N I S R Y S F D N L P E K Y W R K Y Q Y A S R F V Q L V R S K S P K I T Y F T R Y A K C I L M E N S P G A D F E V

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S
S
S T T
S S S S S T T T T S
S S
S S
S S

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence W F Y D G V K I H K T E D F I Q V I E K T G K S Y T L K S E S E V N S L K E E I K M Y M D H A N E G H R I C L A L E S I I S E E E R K T R S

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T S
S S
S S S
B
S S S G G G S
S
S

. . . . . . . . . 220 . .

Sequence A P F F P I I I G R K P

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S
S S

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	T	L	R	S	I	T	S	P	L	V	A	H	R	L	K	P	I	R	Q	K	T	K	K	A	V	V	S	I	L	D	S	E	E	V	C	V	E	L	V	K	E	Y	A	S	Q	E	Y	V	K	E	V	L	Q	I	S	S	D	G	N	T	I	T	I	Y	Y	P	N	G	G	R
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)		G	G	G	G	S						T	T									S	S							T	T	S											T	T												T	T	S	S							G	G	G	G	T
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	G	F	P	L	A	D	R	P	P	S	P	T	D	N	I	S	R	Y	S	F	D	N	L	P	E	K	Y	W	R	K	Y	Q	Y	A	S	R	F	V	Q	L	V	R	S	K	S	P	K	I	T	Y	F	T	R	Y	A	K	C	I	L	M	E	N	S	P	G	A	D	F	E	V
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)						S	S						S							S	T	T			S	S	S	S	S	T	T												T	T	S								S	S							S	S		S	S
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	W	F	Y	D	G	V	K	I	H	K	T	E	D	F	I	Q	V	I	E	K	T	G	K	S	Y	T	L	K	S	E	S	E	V	N	S	L	K	E	E	I	K	M	Y	M	D	H	A	N	E	G	H	R	I	C	L	A	L	E	S	I	I	S	E	E	E	R	K	T	R	S
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			T	T	S							S	S							S	S	S			B					S	S	S	G	G	G	S																																S		S
	.	.	.	.	.	.	.	.	.	220	.	.
Sequence	A	P	F	F	P	I	I	I	G	R	K	P
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	S				S				S