PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c4m6rA_

Fold library id	PDB Header	Molecule	Title
c4m6rA_	PDB header: lyase	Chain: A: PDB Molecule: methylthioribulose-1-phosphate dehydratase;	PDBTitle: structural and biochemical basis for the inhibition of cell death by2 apip, a methionine salvage enzyme

Links to external resources
Added to library: Sat Feb 1 08:21:49 2014

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence M D K E H P R Y L I P E L C K Q F Y H L G W V T G T G G G I S L K H G D E I Y I A P S G V Q K E R I Q P E D M F V C D I N E K D I S G P S P

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T S T S S G G G
T T
B T T S
G G G
G G G
T T S
S
G

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence S K K L K K S Q C T P L F M N A Y T M R G A G A V I H T H S K A A V M A T L L F P G R E F K I T H Q E M I K G I K K C T S G G Y Y R Y D D M

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) G G
B
T T
S
S
S S S
G G G G G
B
T T T
S B
T T S

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence L V V P I I E N T P E E K D L K D R M A H A M N E Y P D S C A V L V R R H G V Y V W G E T W E K A K T M C E C Y D Y L F D I A V S M K K V G

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S
S T T
S T T T S S T T

. . . . . . . . . 220 . . . .

Sequence L D P S Q L P V G E N G I V

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T S
S

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	M	D	K	E	H	P	R	Y	L	I	P	E	L	C	K	Q	F	Y	H	L	G	W	V	T	G	T	G	G	G	I	S	L	K	H	G	D	E	I	Y	I	A	P	S	G	V	Q	K	E	R	I	Q	P	E	D	M	F	V	C	D	I	N	E	K	D	I	S	G	P	S	P
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			T	T	S																T	S	S	G	G	G									T	T						B	T	T	S		G	G	G			G	G	G						T	T	S						S		G
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	S	K	K	L	K	K	S	Q	C	T	P	L	F	M	N	A	Y	T	M	R	G	A	G	A	V	I	H	T	H	S	K	A	A	V	M	A	T	L	L	F	P	G	R	E	F	K	I	T	H	Q	E	M	I	K	G	I	K	K	C	T	S	G	G	Y	Y	R	Y	D	D	M
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	G	G				B		T	T														S																	S		S	S						S		G	G	G	G	G		B		T	T	T		S	B			T	T	S
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	L	V	V	P	I	I	E	N	T	P	E	E	K	D	L	K	D	R	M	A	H	A	M	N	E	Y	P	D	S	C	A	V	L	V	R	R	H	G	V	Y	V	W	G	E	T	W	E	K	A	K	T	M	C	E	C	Y	D	Y	L	F	D	I	A	V	S	M	K	K	V	G
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)										S																S	T	T		S					T	T	T							S	S																								T	T
	.	.	.	.	.	.	.	.	.	220	.	.	.	.
Sequence	L	D	P	S	Q	L	P	V	G	E	N	G	I	V
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			T	T	S				S