PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c4lrtC_

Fold library id	PDB Header	Molecule	Title
c4lrtC_	PDB header: lyase/oxidoreductase	Chain: C: PDB Molecule: 4-hydroxy-2-oxovalerate aldolase;	PDBTitle: crystal and solution structures of the bifunctional enzyme2 (aldolase/aldehyde dehydrogenase) from thermomonospora curvata,3 reveal a cofactor-binding domain motion during nad+ and coa4 accommodation whithin the shared cofactor-binding site

Links to external resources
Added to library: Sat Sep 7 08:26:23 2013

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence P R V R I T D S T L R D G S H A M A H Q F T E E Q V R A T V H A L D A A G V E V I E V S H G D G L G G S S F N Y G F S A V D E I D L V A A A

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T T T
T
S
T T
T T
B T T T B
S S

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence V D E A V N A K I A V L L L P G V G T V R D L K R A H D A G A S V A R I A T H C T E A D V S C Q H F A A A R E L G M E T V G F L M L A H R I

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S
B T T B
T
T T
G G G
T T
S G G G S

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence G P E E L A R Q A R I M V D A G A Q C V Y V V D S A G A L V L S D V Q A R V Q A L V R E I G H E A Q V G F H G H Q N L S L G V A N S V L A Y

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T
S
T T S
T T T T S
B
T T S

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240 . . . . . . . . . 250 . . . . . . . . . 260 . . . . . . . . . 270 . . . . . . . . . 280

Sequence Q N G A R Q I D G A L C A L G A G A G N S P T E I L A A T F E R L N I E T G V N V Q A A L A A A E E V V R P Y L P R L P W A D R A A I V Q G

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T
B G G G
S S T T
B
B T T
T T G G G
S S

. . . . . . . . . 290 . . . . . . . . . 300 . . . . . . . . . 310 . . . . . . . . . 320 . . . . . . . . . 330 . . . . .

Sequence Y A G V Y S S F L L H A E R A A E R Y G V P A H E I L Q R V G E A G Y V G G Q E D M I I D I A V Q L A E E R H

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T
T T T S
T
T T
T

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	P	R	V	R	I	T	D	S	T	L	R	D	G	S	H	A	M	A	H	Q	F	T	E	E	Q	V	R	A	T	V	H	A	L	D	A	A	G	V	E	V	I	E	V	S	H	G	D	G	L	G	G	S	S	F	N	Y	G	F	S	A	V	D	E	I	D	L	V	A	A	A
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)											T						T	T	T																		T							S		T	T		T	T			B	T	T	T	B			S	S
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	V	D	E	A	V	N	A	K	I	A	V	L	L	L	P	G	V	G	T	V	R	D	L	K	R	A	H	D	A	G	A	S	V	A	R	I	A	T	H	C	T	E	A	D	V	S	C	Q	H	F	A	A	A	R	E	L	G	M	E	T	V	G	F	L	M	L	A	H	R	I
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)					S	S									B	T	T	B												T										T	T		G	G	G											T	T									S	G	G	G	S
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	G	P	E	E	L	A	R	Q	A	R	I	M	V	D	A	G	A	Q	C	V	Y	V	V	D	S	A	G	A	L	V	L	S	D	V	Q	A	R	V	Q	A	L	V	R	E	I	G	H	E	A	Q	V	G	F	H	G	H	Q	N	L	S	L	G	V	A	N	S	V	L	A	Y
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																T		S							T	T	S				T															T	T	T	S							B		T	T	S
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280
Sequence	Q	N	G	A	R	Q	I	D	G	A	L	C	A	L	G	A	G	A	G	N	S	P	T	E	I	L	A	A	T	F	E	R	L	N	I	E	T	G	V	N	V	Q	A	A	L	A	A	A	E	E	V	V	R	P	Y	L	P	R	L	P	W	A	D	R	A	A	I	V	Q	G
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)		T	T							B	G	G	G		S	S	T	T		B		B											T	T																	T	T	G	G	G		S	S
	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.
Sequence	Y	A	G	V	Y	S	S	F	L	L	H	A	E	R	A	A	E	R	Y	G	V	P	A	H	E	I	L	Q	R	V	G	E	A	G	Y	V	G	G	Q	E	D	M	I	I	D	I	A	V	Q	L	A	E	E	R	H
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			T			T	T													T	S													T			T	T		T