PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c4kp4B_

Fold library id	PDB Header	Molecule	Title
c4kp4B_	PDB header: transferase/signaling protein	Chain: B: PDB Molecule: osmolarity sensor protein envz, histidine kinase;	PDBTitle: deciphering cis-trans directionality and visualizing2 autophosphorylation in histidine kinases.

Links to external resources
Added to library: Sat Feb 15 09:15:11 2014

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence A D D R T L L M A G V S H D L R T P L T R I R A Y A E T I Y N S L G E L D L S T L K E L A E S I N K D I E E C N A I I E Q F I D Y L R T G Q

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T
T T T
T S

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence E M P M E M A D L N A V L G E V I A A E S G Y E R E I E T A L Y P G S I E V K M H P L S I K R A V A N M V V N A A R Y G N G W I K V S S G T

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S
S S S
S S
S S S

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence E P N R A W F Q V E D D G P G I A P E Q R K H L F Q P F V R G D S A R T I S G T G L G L A I V Q R I V D N H N G M L E L G T S E R G G L S I

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S S S
T T T T G G G S
S B
S S
S
S B
T T
T T S S

. . . . . . .

Sequence R A W L P V P

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	A	D	D	R	T	L	L	M	A	G	V	S	H	D	L	R	T	P	L	T	R	I	R	A	Y	A	E	T	I	Y	N	S	L	G	E	L	D	L	S	T	L	K	E	L	A	E	S	I	N	K	D	I	E	E	C	N	A	I	I	E	Q	F	I	D	Y	L	R	T	G	Q
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)															T																		T	T	T																																		T	S
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	E	M	P	M	E	M	A	D	L	N	A	V	L	G	E	V	I	A	A	E	S	G	Y	E	R	E	I	E	T	A	L	Y	P	G	S	I	E	V	K	M	H	P	L	S	I	K	R	A	V	A	N	M	V	V	N	A	A	R	Y	G	N	G	W	I	K	V	S	S	G	T
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																				S			S	S	S								S	S																										S	S	S
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	E	P	N	R	A	W	F	Q	V	E	D	D	G	P	G	I	A	P	E	Q	R	K	H	L	F	Q	P	F	V	R	G	D	S	A	R	T	I	S	G	T	G	L	G	L	A	I	V	Q	R	I	V	D	N	H	N	G	M	L	E	L	G	T	S	E	R	G	G	L	S	I
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)		S	S									S	S					T	T	T	T	G	G	G	S		S	B		S	S			S		S	B																	T	T									T	T	S	S
	.	.	.	.	.	.	.
Sequence	R	A	W	L	P	V	P
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)