PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.0

Fold library entry viewer: c4k5yC_

Fold library id	PDB Header	Molecule	Title
c4k5yC_	PDB header: membrane protein, receptor	Chain: C: PDB Molecule: corticotropin-releasing factor receptor 1, t4-lysozyme	PDBTitle: crystal structure of human corticotropin-releasing factor receptor 12 (crf1r) in complex with the antagonist cp-376395

Links to external resources
Added to library: Sat Jul 20 08:48:07 2013

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence H V A A I I N Y L G H C I S L V A L L V A F V L F L R A R S I R C L R N I I H A N L I A A F I L R N A T W F V V Q L T M S P E V H Q S N V G

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S G G G G S T T S S

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence W C R L V T A A Y N Y F H V T N F F W M F G E G C Y L H T A I V L T D R L R A W M F I C I G W G V P F P I I V A W A I G K L Y Y D N E K C W

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T
T T T T
G G G

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence A G K R P G V Y T D Y I Y Q G P M A L V L L I N F I F L F N I V R I L M T K L R A S T T S E T I Q A R K A V K A T L V L L P L L G I T Y M L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T
T T
T S S

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240 . . . . . . . .

Sequence A F V N P G E D E V S R V V F I Y F N A F L E S F Q G F F V S V F A C F L N

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S
S S S T

Download: PDB structure FASTA sequence
Hidden Markov model

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Please cite: The Phyre2 web portal for protein modeling, prediction and analysis

Kelley LA et al. Nature Protocols 10, 845-858 (2015) [paper] [Citation link]

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	H	V	A	A	I	I	N	Y	L	G	H	C	I	S	L	V	A	L	L	V	A	F	V	L	F	L	R	A	R	S	I	R	C	L	R	N	I	I	H	A	N	L	I	A	A	F	I	L	R	N	A	T	W	F	V	V	Q	L	T	M	S	P	E	V	H	Q	S	N	V	G
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																												S	G	G	G	G	S																										T	T	S						S
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	W	C	R	L	V	T	A	A	Y	N	Y	F	H	V	T	N	F	F	W	M	F	G	E	G	C	Y	L	H	T	A	I	V	L	T	D	R	L	R	A	W	M	F	I	C	I	G	W	G	V	P	F	P	I	I	V	A	W	A	I	G	K	L	Y	Y	D	N	E	K	C	W
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																																	T														T	T	T															T				G	G	G
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	A	G	K	R	P	G	V	Y	T	D	Y	I	Y	Q	G	P	M	A	L	V	L	L	I	N	F	I	F	L	F	N	I	V	R	I	L	M	T	K	L	R	A	S	T	T	S	E	T	I	Q	A	R	K	A	V	K	A	T	L	V	L	L	P	L	L	G	I	T	Y	M	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T				T	T				T																														S	S
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.
Sequence	A	F	V	N	P	G	E	D	E	V	S	R	V	V	F	I	Y	F	N	A	F	L	E	S	F	Q	G	F	F	V	S	V	F	A	C	F	L	N
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			S				S	S	S																T