PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c4i2yB_

Fold library id	PDB Header	Molecule	Title
c4i2yB_	PDB header: fluorescent protein	Chain: B: PDB Molecule: rgeco1;	PDBTitle: crystal structure of the genetically encoded calcium indicator rgeco1

Links to external resources
Added to library: Sat Jul 27 08:46:18 2013

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence R K W N K A G H A V R A I G R L S S P V V S E R M Y P E D G A L K S E I K K G L R L K D G G H Y A A E V K T T Y K A K K P V Q L P G A Y I V

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S
T T
T T S
S S
S

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence D I K L D I V S H N E D Y T I V E Q C E R A E G R H S A I I K E F M R F K V H M E G S V N G H E F E I E G E G E G R P Y E A F Q T A K L K V

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T S S
S
S S T T T T T T

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence T K G G P L P F A W D I L S P Q F S K A Y I K H P A D I P D Y F K L S F P E G F R W E R V M N F E D G G I I H V N Q D S S L Q D G V F I Y K

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S
S
S S
G G G T G G G
T T S
B
T T S
T T T T
T T S
T T

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240 . . . . . . . . . 250 . . . . . . . . . 260 . . . . . . . . . 270 . . . . . . . . . 280

Sequence V K L R G T N F P P D G P V M Q K K T M G W E A T R D Q L T E E Q I A E F K E A F S L F D K D G D G T I T T K E L G T V M R S L G Q N P T E

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T S T T T T T
B
T T
S S B
T T

. . . . . . . . . 290 . . . . . . . . . 300 . . . . . . . . . 310 . . . . . . . . . 320 . . . . . . . . . 330 . . . . . . . . . 340 . . . . . . . . . 350

Sequence A E L Q D M I N E V D A D G D G T F D F P E F L T M M A R K M N D T D S E E E I R E A F R V F D K D G N G Y I G A A E L R H V M T D L G E T

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T
S S
B B
T T
S S
T

. . . . . . . . . 360 . . . . . . . . . 370 . . . . . . . .

Sequence D E E V D E M I R V A D I D G D G Q V N Y E E F V Q M M

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S S S S

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	R	K	W	N	K	A	G	H	A	V	R	A	I	G	R	L	S	S	P	V	V	S	E	R	M	Y	P	E	D	G	A	L	K	S	E	I	K	K	G	L	R	L	K	D	G	G	H	Y	A	A	E	V	K	T	T	Y	K	A	K	K	P	V	Q	L	P	G	A	Y	I	V
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																		S											T	T													T	T	S														S	S							S
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	D	I	K	L	D	I	V	S	H	N	E	D	Y	T	I	V	E	Q	C	E	R	A	E	G	R	H	S	A	I	I	K	E	F	M	R	F	K	V	H	M	E	G	S	V	N	G	H	E	F	E	I	E	G	E	G	E	G	R	P	Y	E	A	F	Q	T	A	K	L	K	V
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)											T	T	S	S																S		S	S												T	T													T	T	T	T
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	T	K	G	G	P	L	P	F	A	W	D	I	L	S	P	Q	F	S	K	A	Y	I	K	H	P	A	D	I	P	D	Y	F	K	L	S	F	P	E	G	F	R	W	E	R	V	M	N	F	E	D	G	G	I	I	H	V	N	Q	D	S	S	L	Q	D	G	V	F	I	Y	K
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			S		S		S	S		G	G	G	T	G	G	G			T	T	S		B			T	T	S							T	T	T	T											T	T	S													T	T
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280
Sequence	V	K	L	R	G	T	N	F	P	P	D	G	P	V	M	Q	K	K	T	M	G	W	E	A	T	R	D	Q	L	T	E	E	Q	I	A	E	F	K	E	A	F	S	L	F	D	K	D	G	D	G	T	I	T	T	K	E	L	G	T	V	M	R	S	L	G	Q	N	P	T	E
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)										T	T	S	T	T	T	T	T									B																				T	T		S	S	B													T	T
	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350
Sequence	A	E	L	Q	D	M	I	N	E	V	D	A	D	G	D	G	T	F	D	F	P	E	F	L	T	M	M	A	R	K	M	N	D	T	D	S	E	E	E	I	R	E	A	F	R	V	F	D	K	D	G	N	G	Y	I	G	A	A	E	L	R	H	V	M	T	D	L	G	E	T
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)												T	T		S	S			B										B																				T	T		S	S															T
	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.
Sequence	D	E	E	V	D	E	M	I	R	V	A	D	I	D	G	D	G	Q	V	N	Y	E	E	F	V	Q	M	M
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)														S	S	S	S	S