PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c4hw9E_

Fold library id	PDB Header	Molecule	Title
c4hw9E_	PDB header: membrane protein	Chain: E: PDB Molecule: mechanosensitive channel mscs;	PDBTitle: crystal structure of helicobacter pylori mscs (closed state)

Links to external resources
Added to library: Sat Feb 16 08:47:32 2013

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence F G I I L I K A V I V F C I G F Y F S F F L R N K T M K L L S K K D E I L A N F V A Q V T F I L I L I I T T I I A L S T L G V Q T T S I I T

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T T T T
S S
T T T
T

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence V L G T V G I A V A L A L K D Y L S S I A G G I I L I I L H P F K K G D I I E I S G L E G K V E A L N F F N T S L R L H D G R L A V L P N R

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T
S
T T
T T
S S S S S S

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence S V A N S N I I N S N N T A C R R I E W V C G V G Y G S D I E L V H K T I K D V I D T M E K I D K N M P T F I G I T D F G S S S L N F T I R

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T S
B S T T S S
T T S
T T T
S S
S S S
S S S

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240 . . . . . . . . . 250 . . .

Sequence V W A K I E D G I F N V R S E L I E R I K N A L D A N H I E I P F N K L D I A I K N Q

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T T T T T

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	F	G	I	I	L	I	K	A	V	I	V	F	C	I	G	F	Y	F	S	F	F	L	R	N	K	T	M	K	L	L	S	K	K	D	E	I	L	A	N	F	V	A	Q	V	T	F	I	L	I	L	I	I	T	T	I	I	A	L	S	T	L	G	V	Q	T	T	S	I	I	T
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																						T	T	T	T					T		S	S																											T	T	T			T
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	V	L	G	T	V	G	I	A	V	A	L	A	L	K	D	Y	L	S	S	I	A	G	G	I	I	L	I	I	L	H	P	F	K	K	G	D	I	I	E	I	S	G	L	E	G	K	V	E	A	L	N	F	F	N	T	S	L	R	L	H	D	G	R	L	A	V	L	P	N	R
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)													T																T		S			T	T						T	T										S	S							S	S	S	S
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	S	V	A	N	S	N	I	I	N	S	N	N	T	A	C	R	R	I	E	W	V	C	G	V	G	Y	G	S	D	I	E	L	V	H	K	T	I	K	D	V	I	D	T	M	E	K	I	D	K	N	M	P	T	F	I	G	I	T	D	F	G	S	S	S	L	N	F	T	I	R
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			T	T	S				B	S	T	T	S	S												T	T	S		T	T												T		S	S			S	S	S											S	S	S
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.
Sequence	V	W	A	K	I	E	D	G	I	F	N	V	R	S	E	L	I	E	R	I	K	N	A	L	D	A	N	H	I	E	I	P	F	N	K	L	D	I	A	I	K	N	Q
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)									T	T															T	T	T	T