PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c4hsyA_

Fold library id	PDB Header	Molecule	Title
c4hsyA_	PDB header: oxidoreductase	Chain: A: PDB Molecule: ketoreductase siam;	PDBTitle: crystal structure of ketoreductase siam from streptomyces sp. a7248

Links to external resources
Added to library: Sat Nov 9 09:26:31 2013

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence A L S G K V A L V T G G S R G L G R A M A L R L A R D G A A V A I V Y V S D D S S A K E T Q G E I E R L G G T A R S Y R C D V S D A E Q V T

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S T
S S T T T S S
T
S S

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence R C V K A V T A D L G P V D I L V N N A G I I R D G L A A S I K D E D Y D A V M N T N L K G A F L F I K A C Y F G F I R K R S G S I I N I S

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T
S
S
B
T T S
T T

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence S V S G V F G S A G Q A N Y A S A K A G L I G L T K S I A K E L A E R N V R C N A V A P G L I A T D K R L D P V P M R R F G R P D E V A G L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T B S G G G T
S B
T T T T
T T
B
T T

. . . . . . . . . 220 . . . . . . . . . 230 . . . . .

Sequence V A F L A G D E S S Y I T G Q V V C V D G G M A M

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S S T T T T
S
S S S T T

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	A	L	S	G	K	V	A	L	V	T	G	G	S	R	G	L	G	R	A	M	A	L	R	L	A	R	D	G	A	A	V	A	I	V	Y	V	S	D	D	S	S	A	K	E	T	Q	G	E	I	E	R	L	G	G	T	A	R	S	Y	R	C	D	V	S	D	A	E	Q	V	T
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)				S							T		S	S	T												T	T								S	S																T										S	S
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	R	C	V	K	A	V	T	A	D	L	G	P	V	D	I	L	V	N	N	A	G	I	I	R	D	G	L	A	A	S	I	K	D	E	D	Y	D	A	V	M	N	T	N	L	K	G	A	F	L	F	I	K	A	C	Y	F	G	F	I	R	K	R	S	G	S	I	I	N	I	S
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)										T		S		S												B		T	T	S														T																		T
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	S	V	S	G	V	F	G	S	A	G	Q	A	N	Y	A	S	A	K	A	G	L	I	G	L	T	K	S	I	A	K	E	L	A	E	R	N	V	R	C	N	A	V	A	P	G	L	I	A	T	D	K	R	L	D	P	V	P	M	R	R	F	G	R	P	D	E	V	A	G	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)									T	T	B																					S	G	G	G	T										S	B					T	T	T	T		T	T				B						T	T
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.
Sequence	V	A	F	L	A	G	D	E	S	S	Y	I	T	G	Q	V	V	C	V	D	G	G	M	A	M
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)						S	S	T	T	T	T			S						S	S	S	T	T