PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c4gz1B_

Fold library id	PDB Header	Molecule	Title
c4gz1B_	PDB header: hydrolase/dna	Chain: B: PDB Molecule: tyrosyl-dna phosphodiesterase 2;	PDBTitle: mus musculus tdp2 reaction product (5'-phosphorylated dna)-mg2+2 complex at 1.5 angstroms resolution

Links to external resources
Added to library: Sat Nov 3 15:46:32 2012

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence T I S F I T W N I D G L D G C N L P E R A R G V C S C L A L Y S P D V V F L Q E V I P P Y C A Y L K K R A A S Y T I I T G N E E G Y F T A I

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T
T T
S
T T T S
S S S S

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence L L K K G R V K F K S Q E I I P F P N T K M M R N L L C V N V S L G G N E F C L M T S H L E S T R E H S A E R I R Q L K T V L G K M Q E A P

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T T
T T
S S
T T
B
S G G G S

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence D S T T V I F A G D T N L R D Q E V I K C G G L P D N V F D A W E F L G K P K H C Q Y T W D T K A N N N L R I P A A Y K H R F D R I F F R A

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T S
T
S
T T
T T
G G G S
S T T T
T T
S S

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240 . . . . . . . .

Sequence E E G H L I P Q S L D L V G L E K L D C G R F P S D H W G L L C T L N V V L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S T T T
S
T T S S
S
S B

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	T	I	S	F	I	T	W	N	I	D	G	L	D	G	C	N	L	P	E	R	A	R	G	V	C	S	C	L	A	L	Y	S	P	D	V	V	F	L	Q	E	V	I	P	P	Y	C	A	Y	L	K	K	R	A	A	S	Y	T	I	I	T	G	N	E	E	G	Y	F	T	A	I
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)											T	T			T	T																		S																			T	T	T						S		S	S	S	S
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	L	L	K	K	G	R	V	K	F	K	S	Q	E	I	I	P	F	P	N	T	K	M	M	R	N	L	L	C	V	N	V	S	L	G	G	N	E	F	C	L	M	T	S	H	L	E	S	T	R	E	H	S	A	E	R	I	R	Q	L	K	T	V	L	G	K	M	Q	E	A	P
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)				T	T	T												T	T		S	S												T	T									B				S	G	G	G																		S
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	D	S	T	T	V	I	F	A	G	D	T	N	L	R	D	Q	E	V	I	K	C	G	G	L	P	D	N	V	F	D	A	W	E	F	L	G	K	P	K	H	C	Q	Y	T	W	D	T	K	A	N	N	N	L	R	I	P	A	A	Y	K	H	R	F	D	R	I	F	F	R	A
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T	T	S																			T		S		T	T								T	T			G	G	G	S		S			T	T	T			T	T			S	S
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.
Sequence	E	E	G	H	L	I	P	Q	S	L	D	L	V	G	L	E	K	L	D	C	G	R	F	P	S	D	H	W	G	L	L	C	T	L	N	V	V	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	S	T	T	T												S			T	T	S	S		S		S	B